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Fluid overload: clinical outcomes in pediatric intensive care unit
Gomes, Romina Aparecida dos Santos; Azevedo, Lorena Ferreira; Simões, Bruna Pessanha Cerqueira; Detomi, Letícia Silva; Rodrigues, Karla Emília de Sá; Rodrigues, Adriana Teixeira; Melo, Maria do Carmo Barros de; Fonseca, Jaisson Gustavo da.
Afiliación
  • Gomes, Romina Aparecida dos Santos; Universidade Federal de Minas Gerais. Faculdade de Medicina. Belo Horizonte. BR
  • Azevedo, Lorena Ferreira; Universidade Federal de Minas Gerais. Hospital das Clínicas. Belo Horizonte. BR
  • Simões, Bruna Pessanha Cerqueira; Universidade Federal de Minas Gerais. Hospital das Clínicas. Belo Horizonte. BR
  • Detomi, Letícia Silva; Universidade Federal de Minas Gerais. Hospital das Clínicas. Belo Horizonte. BR
  • Rodrigues, Karla Emília de Sá; Universidade Federal de Minas Gerais. Faculdade de Medicina. Belo Horizonte. BR
  • Rodrigues, Adriana Teixeira; Universidade Federal de Minas Gerais. Faculdade de Medicina. Belo Horizonte. BR
  • Melo, Maria do Carmo Barros de; Universidade Federal de Minas Gerais. Faculdade de Medicina. Belo Horizonte. BR
  • Fonseca, Jaisson Gustavo da; Universidade Federal de Minas Gerais. Hospital das Clínicas. Belo Horizonte. BR
J. pediatr. (Rio J.) ; J. pediatr. (Rio J.);99(3): 241-246, May-June 2023. tab
Article en En | LILACS-Express | LILACS | ID: biblio-1440471
Biblioteca responsable: BR1.1
ABSTRACT
Abstract Objective The aim of this study was to analyze the effects of fluid overload related to mechanical ventilation, renal replacement therapy, and evolution to discharge or death in critically ill children. Methods A retrospective study in a Pediatric Intensive Care Unit for two years. Patients who required invasive ventilatory support and vasopressor and/or inotropic medications were considered critically ill. Results 70 patients were included. The mean age was 6.8 ± 6 years. There was a tolerable increase in fluid overload during hospitalization, with a median of 2.45% on the first day, 5.10% on the third day, and 8.39% on the tenth day. The median fluid overload on the third day among those patients in pressure support ventilation mode was 4.80% while the median of those who remained on controlled ventilation was 8.45% (p = 0.039). Statistical significance was observed in the correlations between fluid overload measurements on the first, third, and tenth days of hospitalization and the beginning of renal replacement therapy (p = 0.049) and between renal replacement therapy and death (p = 0.01). The median fluid overload was 7.50% in patients who died versus 4.90% in those who did not die on the third day of hospitalization (p = 0.064). There was no statistically significant association between death and the variables sex or age. Conclusions The fluid overload on the third day of hospitalization proved to be a determinant for the clinical outcomes of weaning from mechanical ventilation, initiation of renal replacement therapy, discharge from the intensive care unit, or death among these children.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J. pediatr. (Rio J.) Asunto de la revista: PEDIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J. pediatr. (Rio J.) Asunto de la revista: PEDIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil