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Fatal sclerosing mesenteritis: a 7-year-old male autopsy case report
Celis Pinto, Juan Carlos; Hernández Peláez, Lucía; Mendoza Pacas, Guillermo; Mayordomo Colunga, Juan; Balbín, Milagros; Pitiot, Ana; Torres-Rivas, Héctor-Enrique; Blanco Lorenzo, Verónica.
Afiliación
  • Celis Pinto, Juan Carlos; Hospital Universitario Central de Asturias. Pathology Department. Oviedo. ES
  • Hernández Peláez, Lucía; Hospital Universitario Central de Asturias. Pediatric Department. Oviedo. ES
  • Mendoza Pacas, Guillermo; Hospital Universitario Central de Asturias. Pathology Department. Oviedo. ES
  • Mayordomo Colunga, Juan; Hospital Universitario Central de Asturias. Pediatric Intesive Care Unit. Oviedo. ES
  • Balbín, Milagros; Hospital Universitario Central de Asturias. Medicine Laboratory. Oviedo. ES
  • Pitiot, Ana; Hospital Universitario Central de Asturias. Medicine Laboratory. Oviedo. ES
  • Torres-Rivas, Héctor-Enrique; Hospital Universitario Central de Asturias. Pathology Department. Oviedo. ES
  • Blanco Lorenzo, Verónica; Hospital Universitario Central de Asturias. Pathology Department. Oviedo. ES
Autops. Case Rep ; 13: e2023434, 2023. graf
Article en En | LILACS-Express | LILACS | ID: biblio-1439480
Biblioteca responsable: BR1.1
ABSTRACT
ABSTRACT Sclerosing Mesenteritis (SM) is a rare diagnosis, particularly in pediatric patients, and is typically non-fatal when appropriately treated. Although molecular and immunohistochemical alterations have been described, no pathognomonic signature has been identified for this entity. This report presents a case of a seven-year-old boy who suffered sudden cardiorespiratory arrest. Upon autopsy, he was found to have multicentric SM on the upper mesentery, which led to bowel wall thinning and abdominal bleeding with bacterial translocation. We performed comprehensive morphological, immunohistochemical, and molecular analyses. SM is an atypical disorder with diverse clinical manifestations, including a rare but potentially fatal course. Early diagnosis is critical, given its potential severity. To our knowledge, this is the first case report of pediatric mortality linked to SM. Our findings emphasize the importance of increased awareness and early detection of SM in pediatric patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Tipo de estudio: Prognostic_studies / Screening_studies Idioma: En Revista: Autops. Case Rep Asunto de la revista: Anatomia / Patologia Cl¡nica / Patologia Legal Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Brasil
Texto completo
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Imprimir
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Tipo de estudio: Prognostic_studies / Screening_studies Idioma: En Revista: Autops. Case Rep Asunto de la revista: Anatomia / Patologia Cl¡nica / Patologia Legal Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Brasil