Altitude effect on sleep quality and serum melatonin levels in Chilean mining workers / Efecto de la Altitud en la calidad de sueño y niveles séricos de melatonina en trabajadores mineros en Chile
J. health med. sci. (Print)
; 6(2): 161-167, abr.-jun. 2020. ilus
Article
en En
| LILACS
| ID: biblio-1391052
Biblioteca responsable:
CL1.1
ABSTRACT
High altitude (HA) mining operations are a very important business in Chile, but reduced availability of oxygen affects the sleep quality, increasing the risk of accidents. An important regulator of sleep-wake cycle is the hormone Melatonin, produced by pineal gland as a sleep inductor. The aim of this study is to evaluate the effect of high altitude (4,500 m) on the quality of sleep of workers undergoing to Chronic Intermittent Hypobaric Hypoxia (CIHH) using self-reported surveys of sleepiness and sleep quality, measurement of sleep apnea (using nocturnal oximetry) and serum levels of melatonin. The Desaturation index (ID4) results revealed higher HA scores compared to sea level (SL). Regarding melatonin levels, the results show that it is increased in HA versus SL and this increase would be related to oxygen saturation during sleep. These data link sleep quality in HA to its melatonin levels, suggesting that melatonin may be a potential biomarker for sleep quality.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Mal de Altura
/
Mineros
/
Calidad del Sueño
/
Melatonina
Límite:
Humans
/
Male
País/Región como asunto:
America do sul
/
Chile
Idioma:
En
Revista:
J. health med. sci. (Print)
Asunto de la revista:
Medicina
Año:
2020
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile