Your browser doesn't support javascript.
loading
Comparison of Oncostatin M in Patients with Chronic Periodontitis with and without Diabetes
Kolluri, Amulya; Gopalkrishna, Pratibha; Josyula, Venkat Rao; Gatta, Aditya Kiran; Chakravarthy, Kalyana Pentapati.
Afiliación
  • Kolluri, Amulya; Manipal Academy of Higher Education. Manipal College of Dental Sciences. Department of Periodontology. Manipal. IN
  • Gopalkrishna, Pratibha; Manipal Academy of Higher Education. Manipal College of Dental Sciences. Department of Periodontology. Manipal. IN
  • Josyula, Venkat Rao; Manipal Academy of Higher Education. Manipal College of Pharmaceutical Sciences. Department of Pharmaceutical Biotechnology. Manipal. IN
  • Gatta, Aditya Kiran; Manipal Academy of Higher Education. Manipal College of Pharmaceutical Sciences. Department of Pharmaceutical Biotechnology. Manipal. IN
  • Chakravarthy, Kalyana Pentapati; Manipal Academy of Higher Education. Manipal College of Dental Sciences. Department of Public Health Dentistry. Manipal. IN
Pesqui. bras. odontopediatria clín. integr ; 22: e210136, 2022. tab
Article en En | LILACS, BBO | ID: biblio-1365223
Biblioteca responsable: BR1264.1
ABSTRACT
Abstract

Objective:

To compare the Oncostatin M (OSM) concentrations in tissues of patients with chronic periodontitis with and without diabetes. Material and

Methods:

Sixty-four subjects visiting the dental outpatient department were categorized as "healthy" (Group 1), "periodontitis" (Group 2), and "diabetes with periodontitis" (Group 3) groups. The clinical oral examination included assessment of plaque, gingivitis, probing depth, clinical attachment level. Blood glucose was assessed for group 3 patients. OSM concentration in the tissues was assessed using ELISA in all groups.

Results:

The mean OSM was 0.02 ± 0.04 pg/mg in the healthy group, 0.12 ± 0.09 pg/mg in the chronic periodontitis group and 0.13 ± 0.10 pg/mg in the diabetes-periodontitis group. A significantly higher mean OSM was seen in Group 2 and Group 3 than Group 1. The amount of OSM positively correlated with probing depth and clinical attachment level.

Conclusion:

Periodontal disease causes a rise in Oncostatin M, independent of the diabetic status. Expression of OSM in the gingival tissues can serve as an inflammatory marker.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Índice de Placa Dental / Citocinas / Diabetes Mellitus / Oncostatina M / Periodontitis Crónica Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Brasil
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Índice de Placa Dental / Citocinas / Diabetes Mellitus / Oncostatina M / Periodontitis Crónica Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Brasil