The long-term impact of the leprosy post-exposure prophylaxis (LPEP) program on leprosy incidence: a modelling study
s.l; s.n; 2021. 14 p. tab, graf.
Non-conventional
en En
| SES-SP, HANSEN, CONASS, HANSENIASE, SESSP-ILSLPROD, SES-SP, SESSP-ILSLACERVO, SES-SP
| ID: biblio-1292662
Biblioteca responsable:
BR191.1
Ubicación: BR191.1; 9805/S
ABSTRACT
The Leprosy Post-Exposure Prophylaxis (LPEP) program explored the feasibility and impact of contact tracing and the provision of SDR to eligible contacts of newly diagnosed leprosy patients in states or districts of Brazil, India, Indonesia, Myanmar, Nepal, Sri Lanka and Tanzania. This study investigated the long-term impact of the LPEP program on the leprosy new case detection rate (NCDR). Our results show that LPEP could reduce the NCDR beyond the impact of the routine leprosy control programme and that many new cases could be prevented. The benefit of LPEP increases gradually over time. LPEP could accelerate the time of reaching predicted NCDR levels of 2040 under routine program by up to six years. Furthermore, we highlighted how the impact varies between countries due to differences in the number of contacts per index patient screened and differences in leprosy epidemiology and national control programme. Generally, including both household contacts and neighbours (> 20 contacts per index patient) would yield the highest impact.
Texto completo:
1
Colección:
06-national
/
BR
Base de datos:
CONASS
/
HANSEN
/
HANSENIASE
/
SES-SP
/
SESSP-ILSLACERVO
/
SESSP-ILSLPROD
Asunto principal:
Prevención Primaria
/
Trazado de Contacto
/
Profilaxis Posexposición
/
Lepra
Tipo de estudio:
Diagnostic_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
País/Región como asunto:
Africa
/
America do sul
/
Asia
/
Brasil
Idioma:
En
Año:
2021
Tipo del documento:
Non-conventional