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Association of bone mineral density with chronic obstructive pulmonary disease in postmenopausal women
Xu, Rui; Zhang, Yuan; Chen, Xin-Chun; Li, Yu-Qing; Ma, Ling-Ling; Gong, Rui; Yang, Hong-Ni.
Afiliación
  • Xu, Rui; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Zhang, Yuan; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Chen, Xin-Chun; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Li, Yu-Qing; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Ma, Ling-Ling; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Gong, Rui; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
  • Yang, Hong-Ni; People’s Hospital of Xinjiang Uygur Autonomous Region. Gerontology Center. Urumqi. CN
Rev. invest. clín ; Rev. invest. clín;71(3): 204-210, May.-Jun. 2019. tab, graf
Article en En | LILACS | ID: biblio-1289688
Biblioteca responsable: BR1.1
ABSTRACT
Abstract Background Osteoporosis (OP) is common in patients with chronic obstructive pulmonary disease (COPD). The relationship between OP and COPD has been primarily studied in male patients, and few reports are available in postmenopausal women. Objective The purpose of this study was to investigate the association between bone mineral density (BMD) and COPD in postmenopausal women. Methods This cross-sectional study included 133 clinically stable female ex-smokers with confirmed COPD, and 31 age-matched “ex-smoker” female controls. We analyzed groups according to their airway obstruction category. BMD was measured on dual-energy X-ray absorptiometry images of the left femoral neck. Results Patients with COPD had lower T-scores and higher prevalence of osteopenia/OP than the control group. In the COPD group, the airway obstruction category was significantly associated with the T-score after adjustment for confounders. Multivariate logistic regression analysis showed COPD was an independent marker for increased risk of osteopenia/OP in postmenopausal women. Conclusions COPD and airway obstruction category were strongly related to BMD. Postmenopausal women with COPD, especially those with severe airway obstruction, had a higher prevalence rate and a higher risk of osteopenia and OP than female controls without COPD.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Densidad Ósea / Osteoporosis Posmenopáusica / Posmenopausia / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Aged / Female / Humans Idioma: En Revista: Rev. invest. clín Asunto de la revista: MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: México
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Densidad Ósea / Osteoporosis Posmenopáusica / Posmenopausia / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Aged / Female / Humans Idioma: En Revista: Rev. invest. clín Asunto de la revista: MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: México