Multidrug-resistant tuberculosis at the National Hospital, Abuja, Nigeria
Afr. j. respir. Med
; 4(1): 22-23, 2008.
Article
en En
| AIM
| ID: biblio-1257893
Biblioteca responsable:
CG1.1
ABSTRACT
Five hundred (500) cases of pulmonary tuberculosis (TB) were seen at the Chest Clinic of the National Hospital; Abuja; Nigeria over a 2-year period (2004-2005). The diagnosis and management of multidrug-resistant (MDR) TB were studied as part of DOTS-Plus Directly Observed Treatment Short-course (DOTS) programmes that add components for MDR-TB diagnosis; management; and treatment. The cases of pulmonary TB that showed mycobacterium resistance to rifampicin and isoniazid (MDR-TB) using the Lowenstein Jensen (solid medium) slope at the National Hospital and later using BACTEC 460 available at Zankli Medical Center at Abuja; were treated with the standard WHO recommended regimen for MDR-TB and the outcomes were studied. Twenty cases (4) of MDRTB were recorded; all 20 were also HIV-positive. One (8) died and 19 (95) were apparently cured at the end of therapy. This is the first report of MDR-TB and DOTS-Plus in Nigeria. There is an urgent need to study the MDR-TB pattern in Nigeria as extensive resistant TB (XDR-TB) has now been reported which is even worse prognostically than MDR-TB
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Base de datos:
AIM
Asunto principal:
Tuberculosis Pulmonar
/
Tuberculosis Resistente a Múltiples Medicamentos
/
Terapia por Observación Directa
/
Nigeria
Tipo de estudio:
Prognostic_studies
País/Región como asunto:
Africa
Idioma:
En
Revista:
Afr. j. respir. Med
Año:
2008
Tipo del documento:
Article