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Comparison of the international normalized ratio levels obtainedby portable coagulometer and laboratory in a clinic specializing inoral anticoagulation
Meneghelo, Z M; Barroso, C M Q; Liporace, I L; CORA, A P.
Afiliación
  • Meneghelo, Z M; Instituto Dante Pazzanese deCardiologia. São Paulo. BR
  • Barroso, C M Q; Instituto Dante Pazzanese deCardiologia. São Paulo. BR
  • Liporace, I L; Instituto Dante Pazzanese deCardiologia. São Paulo. BR
  • CORA, A P; Instituto Dante Pazzanese deCardiologia. São Paulo. BR
Int. j. lab. hematol ; 37: 536-543, 2015. ilus
Article en En | SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1063569
Biblioteca responsable: BR79.1
Ubicación: BR79.1
ABSTRACT
Therapy with Vitamin K antagonists (VKA) is effectivein reducing thromboembolic events in various diseases. There arelimitations however, which limit clinical handling and maintainingINR within therapeutic range. Studies have shown that portable coagulometers,when compared to laboratory tests, are more practicaland provide better patient adherence and involvement towardtreatment which results in better INR control. This study aimed toevaluate laboratory obtained INR results compared to two differentportable coagulometers.

Methods:

A prospective study which monitored 1009 patients usingVKA in the Anticoagulation Clinic at the Institute Dante Pazzaneseof Cardiology in S~ao Paulo between July and September 2012.Patient INR values were obtained by the laboratory through venipunctureand then compared to INR values obtained by capillarypuncture from two different portable coagulometers.

Results:

Overall, 1009 patients were included in the study; amongthese, 520 (51.5%) are male with average age of 59.6 years (13–91). The more common indications were atrial fibrillation (49.9%)and mechanical prosthesis (33.7%). The correlation coefficient wasof 0.95 with and 0.88 with INRatio PT Monitor compared to laboratory.In patients with INR 3.0) the correlation was 0.80 with CoaguChek XSPlus and 0.54 with INRatio PT Monitor ...
Asunto(s)
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Colección: 06-national / BR Base de datos: SES-SP / SESSP-IDPCPROD Asunto principal: Inhibidor de Coagulación del Lupus / Relación Normalizada Internacional Tipo de estudio: Observational_studies Idioma: En Revista: Int. j. lab. hematol Año: 2015 Tipo del documento: Article
Buscar en Google
Colección: 06-national / BR Base de datos: SES-SP / SESSP-IDPCPROD Asunto principal: Inhibidor de Coagulación del Lupus / Relación Normalizada Internacional Tipo de estudio: Observational_studies Idioma: En Revista: Int. j. lab. hematol Año: 2015 Tipo del documento: Article