Your browser doesn't support javascript.
loading
Drug-eluting stents vs bare metal stents for the treatment of large coronary vessels
Quizhpe, Arturo R; Feres, Fausto; Costa, José de Ribamar; Abizaid, Alexandre; Maldonado, Galo; Costa, Ricardo; Abizaid, Andrea; Cano, Manuel; Moreira, Adriana; Staico, Rodolfo; Mattos, Luiz Alberto; Tanajura, Luiz Fernando; Chaves, Aurea J; Centemero, Marinella; Sousa, Amanda MR; Sousa, J Eduardo.
Afiliación
  • Quizhpe, Arturo R; Instituto Dante Pazzanese de Cardiologia. BR
  • Feres, Fausto; Instituto Dante Pazzanese de Cardiologia. BR
  • Costa, José de Ribamar; Instituto Dante Pazzanese de Cardiologia. BR
  • Abizaid, Alexandre; Instituto Dante Pazzanese de Cardiologia. BR
  • Maldonado, Galo; Instituto Dante Pazzanese de Cardiologia. BR
  • Costa, Ricardo; Instituto Dante Pazzanese de Cardiologia. BR
  • Abizaid, Andrea; Instituto Dante Pazzanese de Cardiologia. BR
  • Cano, Manuel; Hospital do Coração. BR
  • Moreira, Adriana; Hospital do Coração. BR
  • Staico, Rodolfo; Instituto Dante Pazzanese de Cardiologia. BR
  • Mattos, Luiz Alberto; Instituto Dante Pazzanese de Cardiologia. BR
  • Tanajura, Luiz Fernando; Instituto Dante Pazzanese de Cardiologia. BR
  • Chaves, Aurea J; Instituto Dante Pazzanese de Cardiologia. BR
  • Centemero, Marinella; Instituto Dante Pazzanese de Cardiologia. BR
  • Sousa, Amanda MR; Instituto Dante Pazzanese de Cardiologia. BR
  • Sousa, J Eduardo; Instituto Dante Pazzanese de Cardiologia. BR
Am. heart j ; 154(02): 373-378, aug 2007. ilus
Article en En | SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1059466
Biblioteca responsable: BR79.1
Ubicación: BR79.1
ABSTRACT

BACKGROUND:

Lately drug-eluting stents (DES) have dramatically reduced restenosis rates and need for repeat revascularization in a wide subset of lesion and patients. However, their benefit for the treatment of large vessels (> 3.0 mm) has yet to be established.

OBJECTIVE:

We investigated whether DES are superior to bare metal stents (BMS) in terms of clinical outcomes for the treatment of large coronary vessels.

METHODS:

This study assessed the long-term outcomes (cardiac death, acute myocardial infarction, and need for repeat intervention in the treated vessel) of patients treated with either a DES (Cypher and Taxus) or a BMS of > or = 3.5 mm in diameter. A total of 250 consecutive patients who underwent DES implantation were clinically followed for 1 year and compared to 250 patients who were treated with BMS. Interventions in the setting of acute ST elevation myocardial infarction and treatment of bypass grafts were excluded.

RESULTS:

Cypher was the DES deployed in 70.8% of cases. Most of the enrolled patients were men (78%) with single vessel disease (65.6%). The left anterior descending artery was the culprit vessel in 34.2% of cases. Bare metal stent and DES cohorts had equivalent interpolated reference vessel diameter (3.19 +/- 0.3 mm for BMS vs 3.18 +/- 0.2 for DES; P = .1). Lesion was significantly longer in the group treated with DES (13.4 +/- 5.1 mm for BMS group vs 14.3 +/- 3.5 for DES; P = .0018). After 1 year of clinical follow-up, 95.2% of patients treated with DES and 91.2% of the patients who received BMS were free of major events (P = .2). A trend toward higher target-lesion revascularization was noticed in the group treated with BMS (4.8% vs 1.6%; P = .07).

CONCLUSION:

Percutaneous treatment of large coronary vessels carries a low risk of clinical events irrespective of the type of stent used.
Asunto(s)
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
Colección: 06-national / BR Base de datos: SES-SP / SESSP-IDPCPROD Asunto principal: Angioplastia Coronaria con Balón / Stents / Paclitaxel / Isquemia Miocárdica / Sirolimus / Estenosis Coronaria / Inmunosupresores Idioma: En Revista: Am. heart j Año: 2007 Tipo del documento: Article
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
Colección: 06-national / BR Base de datos: SES-SP / SESSP-IDPCPROD Asunto principal: Angioplastia Coronaria con Balón / Stents / Paclitaxel / Isquemia Miocárdica / Sirolimus / Estenosis Coronaria / Inmunosupresores Idioma: En Revista: Am. heart j Año: 2007 Tipo del documento: Article