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1.
Rev. Flum. Odontol. (Online) ; 3(68): 1-12, set-dez.2025. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1584956

RESUMO

Metástase é o crescimento de células cancerígenas em sítios distantes do órgão de onde se originaram, e a sua ocorrência indica um prognóstico ruim. Em cavidade oral são raras. Podem ocorrer nos tecidos moles, nos maxilares ou em ambos, e são de expressiva importância clínica, pois indicam um estágio disseminado de um câncer, e podem ser o único sintoma de uma malignidade subjacente ainda não diagnosticada. Desse modo, é essencial que o cirurgião-dentista esteja familiarizado com o aspecto clínico e achados radiográficos mais associados a essa patologia. O objetivo desta revisão narrativa de literatura é compilar os principais aspectos sobre as metástases orais para a atuação do clínico. A patogenia das metástases para a cavidade oral é complexa e não totalmente compreendida. Os sítios primários mais frequentes são o câncer de mama, para as metástases nos ossos maxilares; e o câncer de pulmão, para os depósitos nos tecidos moles orais. As regiões orais mais acometidas são a área posterior de mandíbula e a gengiva. As metástases em osso são mais prevalentes do que em tecidos moles. De maneira geral, os homens são mais acometidos, especialmente na quinta a sétima década de vida, e o aspecto clínico das metástases é variável, lembrando lesões inflamatórias ou hiperplásicas, mas com crescimento rápido. Os achados radiográficos são inespecíficos, e podem apresentar características como osso "roído por traças" e aumento irregular dos espaços da membrana periodontal. Conclui-se com essa revisão que é fundamental que o cirurgião-dentista conheça e inclua lesões metastáticas no diagnóstico diferencial das patologias orais, tendo em vista o seu grau elevado de relevância clínica.


Metastasis is the growth of cancer cells in sites distant from the organ from which they originated, and its occurrence indicates a poor prognosis. In the oral cavity they are rare. They can occur in the soft tissues, jaws or both, and are of significant clinical importance, as they indicate a disseminated stage of cancer, and may be the only symptom of an underlying malignancy that has not yet been diagnosed. Therefore, it is essential that the dental surgeon is familiar with the clinical aspect and radiographic findings most associated with this pathology. The aim of this narrative literature review is to compile the main aspects about oral metastases for the clinician's work. The pathogenesis of metastases to the oral cavity is complex and not fully understood. The most frequent primary sites are breast cancer, for metastases in the jaw bones; and lung cancer, for deposits in oral soft tissues. The most affected oral regions are the posterior area of the jaw and the gingival tissue. Metastases in bone are more prevalent than in soft tissues. In general, men are more affected, especially in the fifth to seventh decade of life, and the clinical appearance of metastases is variable, resembling inflammatory or hyperplastic lesions, but with rapid growth. Radiographic findings are nonspecific and may present characteristics such as "moth-eaten" bone and irregular increase in periodontal membrane spaces. This review concludes that it is essential for the dentist to know and include metastatic lesions in the differential diagnosis of oral pathologies, given their high degree of clinical relevance.


Assuntos
Patologia Bucal , Neoplasias Bucais , Diagnóstico Diferencial , Metástase Neoplásica
2.
Rev. Flum. Odontol. (Online) ; 1(66): 180-190, jan-abr.2025. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1570764

RESUMO

A osteonecrose dos maxilares induzida por medicamentos (MRONJ) caracteriza-se por exposição óssea ou osso que pode ser sondado através de fístula intra ou extraoral, em região maxilofacial, e que não cicatriza dentro de oito semanas. A MRONJ é uma condição rara e debilitante que pode causar dor, disfagia e odor desagradável na cavidade oral, afetando pacientes com histórico ou sob uso contínuo de terapia antirreabsortiva, isolada ou associada a imunomoduladores ou drogas antiangiogênicas, mas sem histórico de radioterapia nos maxilares. O objetivo desta revisão narrativa de literatura é compilar os principais aspectos sobre a etiopatogenia da MRONJ e as opções terapêuticas disponíveis. A etiologia da MRONJ é multifatorial, complexa, e não está totalmente compreendida, não havendo um tratamento definitivo, mas diversas modalidades terapêuticas que visam o controle da dor e da progressão da osteonecrose. Conclui-se com essa revisão que o entendimento da etiopatogenia da MRONJ pelo cirurgião-dentista lhe permite adotar medidas preventivas, bem como o conhecimento das modalidades terapêuticas disponíveis lhe possibilita oferecer o manejo adequado para seu paciente, conforme o estágio da doença.


Medication-related osteonecrosis of the jaw (MRONJ) is characterized by exposed bone or bone that can be probed through an intra or extraoral fistula, in the maxillofacial region, which does not heal within eight weeks. MRONJ is a rare and debilitating condition that can cause pain, dysphagia and unpleasant odor in the oral cavity, affecting patients with a history or continuous use of antiresorptive therapy, alone or associated with immunomodulators or antiangiogenic drugs, but without a history of radiotherapy to the jaws. The aim of this narrative literature review is to compile the main aspects about the etiopathogenesis of MRONJ and the available therapeutic options. The etiology of MRONJ is multifactorial, complex, and is not fully understood, with no definitive treatment, but several therapeutic modalities that aim to control pain and the progression of osteonecrosis. It is concluded from this review that the understanding of the etiopathogenesis of MRONJ by the dental surgeon allows him to adopt preventive measures, as well as the knowledge of the therapeutic modalities available allows him to offer the appropriate management for his patient, depending on the stage of the disease.


Assuntos
Osteonecrose , Patologia Bucal , Terapêutica , Osteonecrose da Arcada Osseodentária Associada a Difosfonatos , Ácido Zoledrônico , Arcada Osseodentária
3.
Artigo em Inglês | MEDLINE | ID: mdl-39327201

RESUMO

OBJECTIVES: To describe the historical evolution and dissemination of the Oral Medicine and Oral and Maxillofacial Pathology international societies and associations across the globe, and to provide insights into their significant contributions toward oral health promotion. STUDY DESIGN: This review was conducted in accordance with the JBI Scoping Review Methodology Group guidance. The reporting followed the Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR). RESULTS: Search strategy was applied to 5 databases (MEDLINE/PubMed, Scopus, Embase, Web of Science, Latin American and Caribbean Health Sciences (LILACS)) and grey literature (Google Scholar, Open Grey and ProQuest), as well as additional sources, such as organization websites. Eighty-nine sources were included in this review. Forty-six professional associations/societies were identified, of which 39 represented a country or geopolitical region, 2 represented continents, 2 represented multinational organizations and 3 multinational study groups. CONCLUSIONS: Documentation of the historical establishment and development of Oral Medicine and Oral and Maxillofacial Pathology organizations worldwide is limited and describing these processes remains challenging. Analysis of global data reveals heterogeneous development and distribution, resulting in disparities in accessibility and standardization. Further efforts toward oral health promotion should be implemented.


Assuntos
Medicina Bucal , Patologia Bucal , Humanos , História do Século XX , História do Século XXI , Sociedades Médicas/história , Saúde Global , Promoção da Saúde
4.
Rev. Flum. Odontol. (Online) ; 3(65): 166-174, set-dez.2024. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1567959

RESUMO

Introdução: A angina bolhosa hemorrágica (ABH) é uma condição rara caracterizada pelo surgimento súbito de bolhas de sangue nas mucosas orais e orofaringe. Objetivo: Este trabalho tem como propósito fornecer uma análise abrangente das características clínicas, etiológicas e histopatológicas da angina bolhosa hemorrágica, além de abordar métodos de diagnóstico e opções de tratamento. Materiais e métodos: Foi realizada uma busca por artigos científicos publicados de 2010 a 2023, nas bases de dados Scientific Electronic Library Online (SciELO), US National Library of Medicine (PubMed) e ScienceDirect. Foram coletados artigos em inglês e português utilizando as palavras-chave "angina bolhosa hemorrágica", "estomatite bolhosa hemorrágica benigna", "hemorrhagic bullous angina" e "benign hemorrhagic bullous stomatitis". Conclusão: A ABH é escassamente documentada na literatura, com muitos dados ausentes ou subnotificados. Embora seja uma condição benigna com rápida evolução espontânea, o procedimento diagnóstico deve ser rigoroso para descartar outras possíveis lesões.


Introduction: Bullous hemorrhagic angina (ABH) is a rare condition characterized by the sudden appearance of blood blisters on the oral mucosa and oropharynx. Objective: This work aims to provide a comprehensive analysis of the clinical, etiological and histopathological characteristics of hemorrhagic bullous angina, in addition to addressing diagnostic methods and treatment options. Materials and methods: A search was carried out for scientific articles published between 2010 and 2023, in the Scientific Electronic Library Online (SciELO), US National Library of Medicine (PubMed) and ScienceDirect databases. Articles were found in English and Portuguese using the keywords "hemorrhagic bullous angina", "benign herrhagic bullous stomatitis", "hemorrhagic bullous angina" and "benign herrhagic bullous stomatitis". Conclusion: ABH is scarcely documented in the literature, with many data missing or underreported. Although it is a benign condition with rapid spontaneous evolution, the diagnostic procedure must be rigorous to rule out other possible lesions.


Assuntos
Patologia Bucal , Sangue , Úlceras Orais/diagnóstico , Mucosa Bucal
5.
J Hist Dent ; 72(2): 115-131, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39180731

RESUMO

Pierre Fauchard, considered the father of dentistry, contributed to the development of different fields of dentistry that we know today. However, the contribution of this important individual to the fields of oral medicine and oral and maxillofacial pathology is unknown. This study aimed to identify Pierre Fauchard's contribution to these areas of dentistry. We focused on "Le Chirurgien Dentiste, or Traité des Dents" in both French and English, looking for information about the oral diseases diagnosed and treated by Fauchard. Information on patient history, disease description, treatment applied, and clinical follow-up was collected. A contemporary analysis of the diseases was performed, and the collected data were systematized, reported, and analyzed descriptively, according to the current literature on the addressed topics. Information on conditions such as scurvy, parulides, epulides, oral ulcers, dentoalveolar abscesses, dental alterations, and post-exodontia incidents were elucidated. Findings indicated that Pierre Fauchard described, diagnosed, and treated different soft and hard tissue diseases of great interest to the fields of oral medicine and oral and maxillofacial pathology.


Assuntos
Medicina Bucal , Patologia Bucal , Medicina Bucal/história , França , História do Século XIX , Patologia Bucal/história , Humanos , Doenças da Boca/história , História da Odontologia , História do Século XX
6.
Med Oral Patol Oral Cir Bucal ; 29(5): e698-e703, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39088714

RESUMO

BACKGROUND: Brazilian Oral Pathology (OP) and Oral Medicine (OM) have gained significant international recognition. However, no study has yet evaluated the impact of citations in scientific publications. Therefore, this study aimed to analyze the impact of citations from Brazilian researchers in OP and OM over the last two decades. MATERIAL AND METHODS: This was a cross-sectional study involving 50 researchers linked to postgraduate programs in OP/OM. Data collected from each professional's Lattes curriculum included gender, academic affiliation, the corporate category of the institution, and location. The number of papers published and citations received between 2004 to 2013 and 2014 to 2023 was also collected from the Web of Science database. RESULTS: Most researchers were male (56%) and from public institutions (90%), mainly in the Southeast region (60%). Over two decades, they collectively published 8,033 scientific articles, with significant growth (p<0.001) from to 2004-2013 to 2014-2023. While the average citations per researcher did not differ significantly between 2004-2013 and 2014-2023 (p=0.538), there was a notable 67.67% increase in citations in the last decade. CONCLUSIONS: Brazilian researchers in the areas of OP and OM have demonstrated a significant academic impact over the past two decades, with a marked increase in publications and citations over the last ten years. This highlights the contribution of Brazilians to the global scientific community in these areas.


Assuntos
Bibliometria , Medicina Bucal , Patologia Bucal , Brasil , Estudos Transversais , Patologia Bucal/estatística & dados numéricos , Humanos , Editoração/estatística & dados numéricos , Fatores de Tempo , Masculino , Feminino , Pesquisadores/estatística & dados numéricos
7.
J. Oral Diagn ; 9Jul. 2024. tab, ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1571113

RESUMO

Objectives: The aim of this study was to characterize the main characteristics of this disease in relation to diagnosis, clinical aspects, progression and treatment as well as correlating them with remission time. Material and Methods: A systematic search was performed following the guidelines given by PRISMA and the Joanna Briggs Institute. PubMed, Web of Science and Scopus were the databases used. Results: The final analysis resulted in 108 articles with 173 clinical cases. The longest remission time for signs and symptoms (>7 weeks) was registered among male patients (p = 0.02) and outside the oral cavity; however no significant correlation was observed (p>0.05). A high risk of bias was the most common rating among the articles analyzed (55%); followed by moderate (27%) and low (18%). The lack of standardization in clinical case report descriptions made it difficult to gain a thorough knowledge of the essential characteristics of the NS patho-logical processes. Conclusion: It is recommended that publications follow the standards recommended by the literature; in addition, studies using advanced technologies to better understand NS's pathological path are recommended so as to propose effective treatments for this disease. (AU)


Assuntos
Humanos , Glândulas Salivares , Sialometaplasia Necrosante , Odontologia Baseada em Evidências , Patologia Bucal , Diagnóstico
8.
J. Oral Diagn ; 9: e20240233, Jul. 2024. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1571517

RESUMO

Basal cell carcinoma (BCC) is the most common skin cancer, but oral involvement is extremely rare. Here, we showed a case of a 71-year-old Caucasian male patient presenting an asymptomatic submucosal nodule in the left buccal mucosa on the same side of a previous BCC skin lesion. Intraoral examination revealed a circumscribed sessile and fibrous mass covered by normal mucosa. An incisional biopsy was performed. Microscopically, the lesion showed uniform, ovoid, dark-staining basaloid cells with medium-sized nuclei and little cytoplasm arranged in islands and strands, invading the underlying connective tissue. These islands demonstrated palisading of the peripheral cells and occasionally central areas with epidermoid differentiation. The final diagnosis was nodular basal cell carcinoma. Although uncommon, recurrent BCC may occur in the oral cavity. (AU)


Assuntos
Humanos , Masculino , Idoso , Recidiva , Carcinoma Basocelular , Patologia Bucal , Cirurgia Bucal
9.
J. Oral Diagn ; 9: e252, Jul. 2024. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1585088

RESUMO

Leishmaniasis and leprosy comprise the group of granulomatous diseases. Although both diseases have a known occurrence in Brazil, their concurrent presence is rare, and few cases have been reported in the literature. We report the case of a 46-year-old male patient co-infected with leprosy and mucosal leishmaniasis. Examination revealed an ulcerated lesion on the nose and a lesion with a granulomatous surface on the palate, in addition to spots on the arms and legs. Histopathological analysis of the oral cavity specimen was suggestive of mucosal leishmaniasis, although no amastigotes were identified. A new biopsy was taken to collect material for PCR and the remaining was subjected to hematoxylin-eosin (H&E) staining. Finally, the diagnosis for Leishmania braziliensis was positive. A skin biopsy suggested the diagnosis of leprosy on the right leg and left knee by Fite-Faraco staining (Ziehl-Neelsen). The results obtained indicated simultaneous infection with M. leprae and L. braziliensis. After diagnosis, the patient was treated for co-infection and has been under follow-up for 2 years without signs of recurrence. The diagnosis of leishmaniasis/leprosy co-infection is challenging because of the broad clinical spectrum. Few cases have been reported in the literature and the dentist may play an important role in its detection. (AU)


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Leishmaniose , Hanseníase , Patologia Bucal , Relatos de Casos , Coinfecção
10.
Rev. Nav. Odontol. On Line ; 51(2): [50-56], 31/06/2024.
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-1578555

RESUMO

O melanoma oral é uma neoplasia maligna de melanócitos, caracterizada por um comportamento agressivo e prognóstico extremamente reservado. Melanomas na cavidade oral são raros e geralmente são diagnosticados em estágio avançado, reduzindo a sobrevida dos pacientes. O objetivo desta revisão narrativa de literatura é compilar os aspectos essenciais do melanoma oral e demais pigmentações para orientar o diagnóstico precoce pelo cirurgião-dentista. Realizou-se uma pesquisa nas bases de dados Pubmed, Embase, Lilacs e Cochrane. O melanoma oral apresenta-se como uma mácula ou nódulo, de coloração castanha ou preta, podendo demonstrar variações na cor e até mesmo despigmentações. Ele tem predileção pelo palato e pela gengiva maxilar, usualmente é assintomático, e aparenta acometer ligeiramente mais o sexo masculino, especialmente entre a 4ª e 7ª décadas de vida. Apesar de possuir características clínicas similares com o melanoma cutâneo, são consideradas variantes distintas. O cirurgião-dentista deve conhecer as principais características clínicas do melanoma oral e demais pigmentações da cavidade oral a fim de realizar o diagnóstico precoce da neoplasia e conduzir o caso adequadamente.


Oral melanoma is a malignant neoplasm of melanocytes, characterized by aggressive behavior and an extremely poor prognosis. Melanomas in the oral cavity are rare and are usually diagnosed at an advanced stage, reducing patient survival. The aim of this narrative literature review is to compile the essential aspects of oral melanoma and other pigmentations to guide early diagnosis by the dentist. Comprehensive searches were conducted in the PubMed, Embase, Lilacs, and Cochrane databases. Oral melanoma typically presents as a macule or nodule, brown or black in color, and may show variations in color and even depigmentation. It has a predilection for the palate and maxillary gingiva, is usually asymptomatic, and affects slightly more males, especially between the 4th and 7th decades of life. Although they share similar clinical characteristics with cutaneous melanoma, they are considered distinct variants. Dentists must be aware of the main clinical characteristics of oral melanoma and other pigmentations of the oral cavity to make an early diagnosis of the neoplasm and manage the case appropriately.


Assuntos
Humanos , Patologia Bucal , Diagnóstico , Melanoma , Neoplasias
11.
Med Oral Patol Oral Cir Bucal ; 29(4): e527-e532, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38615252

RESUMO

BACKGROUND: Oral Pathology (OP) and Oral Medicine (OM) are specialties in dentistry whose main objective is the diagnosis and treatment of oral and maxillofacial diseases, and aspects related to the academic training of professionals and fields of practice are distinct and heterogeneous around the world. This study aimed to evaluate professional training and areas of activity in OP and OM in Latin American countries. MATERIAL AND METHODS: A questionnaire was sent to 11 countries, with a professional in each country responsible for answering it. The questionnaire had 21 questions related to the process of professional training, areas of practice, the existence of scientific events in each country, and also collected demographic and population information. RESULTS: OP and OM are practiced in all the countries studied, but the specialty is not recognized in all of them. Brazil was the first to recognize both as a specialty. Postgraduate programs designed to train specialists are available in various countries. Two countries offer residency programs, 6 countries provide specialization courses, 6 offer master's programs, and 3 have doctoral programs. Brazil boasts the highest number of undergraduate courses (n=412), while Uruguay has the lowest (n=2). Professional societies representing the specialty exist in ten countries. Brazil has the highest number of OP and OM specialists (n=422 and 1,072), while Paraguay has the smallest number (n=1 and 3). CONCLUSIONS: Although both specialties are widely practiced around the globe, professional training, the number of dentists trained and the fields of professional practice are very different between the countries studied.


Assuntos
Medicina Bucal , Patologia Bucal , América Latina , Medicina Bucal/educação , Patologia Bucal/educação , Humanos , Autorrelato
14.
Oral Dis ; 30(4): 2150-2157, 2024 05.
Artigo em Inglês | MEDLINE | ID: mdl-37265065

RESUMO

OBJECTIVE: To identify the teaching-learning process characteristics of Oral Pathology and Medicine (OP&M) related to oral potentially malignant disorders (OPMDs) and oral cancer (OC), in the dental schools' curricula in Mexico, to analyze the approach given to this topic worldwide, and to provide the possible solution strategies. MATERIALS AND METHODS: Questionnaires were sent to OP&M deans and professors from public Mexican Universities to explore the curriculum and academic profile of the dental schools. The recommendations gathered from a workshop with expert professors on the challenges in OPMD/OC teaching were reported. RESULTS: Twenty-two dental schools participated (22 deans, 30 professors). The most widely used strategies were clinical-case resolving (86%) and presentations (73%). Although 77.3% of the programs included maxillofacial lesions, only 40.9% contemplated OPMD/OC. Only 45% of the programs developed community activities for early OC detection. The workshop recommendations were (i) multidisciplinary approach to OPMD/OC teaching, involving OP&M professors in other dental and nondental courses; (ii) implementation of the most effective teaching techniques (currently, problem-based learning and clinical-case presentation) in OP&M curricula; (iii) education of OP&M professors on teaching-learning processes. CONCLUSIONS: These recommendations from the Mexican context, integrated with similar experiences from other countries could contribute to develop a unique, internationally acknowledged OP&M curriculum.


Assuntos
Currículo , Educação em Odontologia , Neoplasias Bucais , Patologia Bucal , Faculdades de Odontologia , México , Humanos , Patologia Bucal/educação , Inquéritos e Questionários , Lesões Pré-Cancerosas
15.
Arq. odontol ; 60: 93-101, 2024. ilus, tab
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1571230

RESUMO

Aim: The aim of this study was to draw a stomatological profile of elderly patients treated at the Stomatology Service of a referral hospital in the city of Belo Horizonte, Minas Gerais ­ Brazil.Methods: Information was collected on the diagnostic hypotheses and definitive diagnoses of the elderly (aged 60 to 98 years) treated at the service, from September 2014 to December 2017. Results: Medical records of 1388 patients were evaluated, and 281 different diagnostic hypotheses were found. For males, there was a higher prevalence in both diagnostic and definitive diagnoses for benign and malignant epithelial neoplasms; In females, there was a higher prevalence, also in the hypotheses and diagnostic definitions, of inflammatory fibrous hyperplasia, related to the use of removable prostheses. Conclusion: Thus, this study evidenced the importance of knowledge about the main alterations that affect the oral cavity of elderly patients, which allows better attention to this population, besides being a pioneering stomatological study in hospital units.


Assuntos
Patologia Bucal , Saúde Pública , Saúde do Idoso , Medicina Bucal , Odontologia Geriátrica
16.
Braz Oral Res ; 37: e126, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38126470

RESUMO

This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil's Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.


Assuntos
Neoplasias de Cabeça e Pescoço , Neoplasias Orofaríngeas , Masculino , Humanos , Pessoa de Meia-Idade , Brasil/epidemiologia , Patologia Bucal , Estudos Transversais , Neoplasias Orofaríngeas/diagnóstico , Neoplasias Orofaríngeas/epidemiologia , Carcinoma de Células Escamosas de Cabeça e Pescoço
17.
J Hist Dent ; 71(3): 194-200, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38039110

RESUMO

Oral and maxillofacial pathology, the branch of dentistry concerning clinical and histopathological diagnosis of pathologies of the oral and maxillofacial region, started to develop in Colombia in the mid- 19th century. Since 1950s, dedicated dental clinicians from different dental schools played an important role in its inception and subsequent development. The first significant wave of progress occurred in the 1970s with the appearance of the first formally trained oral pathologists. It was sometime in the late 1980s and early 1990s that dentists Ines Velez and Benjamin Herazo had separate initiatives and created the first oral pathology postgraduate programs in Bogotá. It was in the late 80's and early 90's that dentists Ines Velez and Benjamin Herazo had their own initiatives and created the first oral pathology postgraduate programs in the city of Bogotá. A concomitant of their achievements was the establishment of the first on-site oral pathology biopsies units and registers at Colegio Odontãlogico Colombiano, Pontificia Universidad Javeriana and Escuela Colombiana de Medicina dental schools. The programs have trained many dentists in the field over the years and two of them remain active and fully accredited. The past and present contributions and leaderships of some academic figures and graduates have allowed a steady evolution of the specialty nationwide. Currently, the ability to manage and overcome educational and professional challenges is necessary to advance the growth of this specialty in this country.


Assuntos
Medicina , Patologia Bucal , Colômbia
18.
Int J Mol Sci ; 24(18)2023 Sep 21.
Artigo em Inglês | MEDLINE | ID: mdl-37762664

RESUMO

In this narrative review, we aim to point out the close relationship between mpox virus (MPXV) infection and the role of saliva as a diagnostic tool for mpox, considering the current molecular approach and in the perspective of OMICs application. The MPXV uses the host cell's rough endoplasmic reticulum, ribosomes, and cytoplasmic proteins to replicate its genome and synthesize virions for cellular exit. The presence of oral mucosa lesions associated with mpox infection is one of the first signs of infection; however, current diagnostic tools find it difficult to detect the virus before the rashes begin. MPXV transmission occurs through direct contact with an infected lesion and infected body fluids, including saliva, presenting a potential use of this fluid for diagnostic purposes. Currently available diagnostic tests for MPXV detection are performed either by real-time quantitative PCR (RT-qPCR) or ELISA, which presents several limitations since they are invasive tests. Despite current clinical trials with restricted sample size, MPXV DNA was detected in saliva with a sensitivity of 85%-100%. In this context, the application of transcriptomics, metabolomics, lipidomics, or proteomics analyses coupled with saliva can identify novel disease biomarkers. Thus, it is important to note that the identification and quantification of salivary DNA, RNA, lipid, protein, and metabolite can provide novel non-invasive biomarkers through the use of OMICs platforms aiding in the early detection and diagnosis of MPXV infection. Untargeted mass spectrometry (MS)-based proteomics reveals that some proteins also expressed in saliva were detected with greater expression differences in blood plasma when comparing mpox patients and healthy subjects, suggesting a promising alternative to be applied in screening or diagnostic platforms for mpox salivary diagnostics coupled to OMICs.


Assuntos
Líquidos Corporais , Doenças Transmissíveis , Humanos , Patologia Bucal , Saliva
19.
Med Oral Patol Oral Cir Bucal ; 28(6): e588-e595, 2023 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-37471299

RESUMO

BACKGROUND: With the COVID-19 pandemic, there was a need to adopt online teaching methods in a generalized and sudden way, a situation that led to unprecedented changes in the routine of post-graduate students and research development. This study aimed to analyze the evaluation of remote teaching by graduates of master's degrees and advisors in master's programs in the Oral Pathology and Oral Medicine who needed to adapt to a remote teaching methodology in the pandemic. MATERIAL AND METHODS: This quantitative study evaluated the remote teaching in the perception of master's graduates and advisors from postgraduate programs in Oral Pathology and Oral Medicine. Data were collected through an online Google forms® questionnaire. RESULTS: Participated in the study 14 master graduates and 14 master's advisors. Master graduates evaluated that the professors had a good performance (p=0.001), that the duration of the classes was adequate (p=0.015), that the interaction with professors was satisfactory (p=0.007), that they had good interaction with the advisor (p=0.001), that they were satisfied with the remote guidance process (p=0.038) and that face-to-face practical activities were missed (p=0.002). Master's advisors reported satisfaction with remote teaching, good adaptation (p=0.018) and motivation for remote teaching (p=0.016), they evaluated that students were cooperative in activities (p=0.019) and that face-to-face practical activities were missed (p=0.002). CONCLUSIONS: Despite the difficulties, remote teaching proved to be an effective alternative to face-to-face teaching.


Assuntos
COVID-19 , Pandemias , Humanos , Brasil , Patologia Bucal , Inquéritos e Questionários
20.
J Oral Pathol Med ; 52(6): 564-566, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37364136

RESUMO

BACKGROUND: Systematic reviews (SRs) have become a popular approach for evidence-based practice, being considered a lens through which evidence is viewed and applied. However, several published studies have been identified as scoping reviews rather than SRs. This methodological error can negatively impact clinical decision-making or new research conceptualization. AIM: This letter focuses on the increasing number of SRs in oral pathology and medicine, highlighting the most frequent methodological mistakes. RESULTS: We providing general guidance to help researchers conceptualize better their SRs and for the critical evaluation of SRs by scientific journal reviewers. CONCLUSION: Clinicians, pathologists, and reviewers, must ensure the quality of the published information.


Assuntos
Patologia Bucal , Publicações , Humanos , Revisões Sistemáticas como Assunto , Medicina Baseada em Evidências
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