RESUMO

BACKGROUND: A 31-year-old man who has suffered since age 3 from diffuse cutaneous leishmaniasis (DCL), a disease with profound physical and psychosocial repercussions and no effective treatment at present, was treated with miltefosine. METHODS: The patient was treated for 120 days, 100 mg/day for 1 week, then 150 mg/day subsequently. RESULTS: Lesions were free of parasites at 43 days, and no signs of infiltration were present at day 76. No adverse side effects were observed. CONCLUSIONS: The dramatic clinical effect of miltefosine in this patient appears to fully justify further evaluation of this experimental therapy in DCL.

Assuntos

Antiprotozoários/uso terapêutico , Leishmaniose Cutânea/tratamento farmacológico , Fosforilcolina/análogos & derivados , Adulto , Humanos , Masculino , Fosforilcolina/uso terapêutico , Resultado do Tratamento , Verrugas/parasitologia

Assuntos

Schistosoma , Verrugas/parasitologia , Adulto , Animais , Anti-Helmínticos/uso terapêutico , Colômbia , Feminino , Humanos , Praziquantel/uso terapêutico , Viagem , Verrugas/tratamento farmacológico , Verrugas/patologia