RESUMO
Salvador Zubirán submitted his thesis for his MD degree in 1923. This thesis falls within the context of the new Mexican physiological medicine and denotes the visionary character of its author. Zubirán appears here as the introducer in Mexico of the physiopharmacological approach in autonomic nervous system disorders.
Assuntos
Doenças do Sistema Nervoso Autônomo/história , Neurologia/história , Sistema Nervoso Parassimpático/fisiologia , Dissertações Acadêmicas como Assunto/história , Adrenérgicos/história , Adrenérgicos/uso terapêutico , Animais , Doenças do Sistema Nervoso Autônomo/classificação , Doenças do Sistema Nervoso Autônomo/diagnóstico , Doenças do Sistema Nervoso Autônomo/fisiopatologia , Colinérgicos/história , Colinérgicos/uso terapêutico , História do Século XIX , História do Século XX , Humanos , México , Modelos Neurológicos , Sistema Nervoso Parassimpático/efeitos dos fármacos , Vagotomia/efeitos adversos , Vagotomia/história , Nervo Vago/fisiologiaRESUMO
The author reviews the treatment of duodenal ulcer from its beginnings with gastroenterostomy one hundred years ago. He points out that treatment has changed as it was better understood that hypersecretion of acid was an important ulcerogenic factor. The Sippy regime, with diet and alkali to neutralize acid, and the resection and vagotomy were introduced. He discusses some aspects of the history of these therapies in Panama and points out the importance of the introduction of H2 receptors blocker and other drugs still under investigation.