RESUMO
BACKGROUND: Despite continuous performance improvements, especially in clinical contexts, a major challenge of Artificial Intelligence based Decision Support Systems (AI-DSS) remains their degree of epistemic opacity. The conditions of and the solutions for the justified use of the occasionally unexplainable technology in healthcare are an active field of research. In March 2024, the European Union agreed upon the Artificial Intelligence Act (AIA), requiring medical AI-DSS to be ad-hoc explainable or to use post-hoc explainability methods. The ethical debate does not seem to settle on this requirement yet. This systematic review aims to outline and categorize the positions and arguments in the ethical debate. METHODS: We conducted a literature search on PubMed, BASE, and Scopus for English-speaking scientific peer-reviewed publications from 2016 to 2024. The inclusion criterion was to give explicit requirements of explainability for AI-DSS in healthcare and reason for it. Non-domain-specific documents, as well as surveys, reviews, and meta-analyses were excluded. The ethical requirements for explainability outlined in the documents were qualitatively analyzed with respect to arguments for the requirement of explainability and the required level of explainability. RESULTS: The literature search resulted in 1662 documents; 44 documents were included in the review after eligibility screening of the remaining full texts. Our analysis showed that 17 records argue in favor of the requirement of explainable AI methods (xAI) or ad-hoc explainable models, providing 9 categories of arguments. The other 27 records argued against a general requirement, providing 11 categories of arguments. Also, we found that 14 works advocate the need for context-dependent levels of explainability, as opposed to 30 documents, arguing for context-independent, absolute standards. CONCLUSIONS: The systematic review of reasons shows no clear agreement on the requirement of post-hoc explainability methods or ad-hoc explainable models for AI-DSS in healthcare. The arguments found in the debate were referenced and responded to from different perspectives, demonstrating an interactive discourse. Policymakers and researchers should watch the development of the debate closely. Conversely, ethicists should be well informed by empirical and technical research, given the frequency of advancements in the field.
Assuntos
Inteligência Artificial , Atenção à Saúde , Humanos , Inteligência Artificial/ética , Atenção à Saúde/ética , Sistemas de Apoio a Decisões Clínicas/ética , União EuropeiaRESUMO
BACKGROUND AND METHODS: Competition regulation has a strong influence on the relative market power of firms. As such, competition regulation can complement industry-specific measures designed to address harms associated with excessive market power in harmful consumer product industries. This study aimed to examine, through a public health lens, assessments and decisions made by competition authorities in four jurisdictions (Australia, South Africa, the United States (US), and the European Union (EU)) involving three harmful consumer product industries (alcoholic beverages, soft drinks, tobacco). We analysed legal case documents, sourced from online public registers and dating back as far as the online records extended, using a narrative approach. Regulatory decisions and harms described by the authorities were inductively coded, focusing on the affected group(s) (e.g., consumers) and the nature of the harms (e.g., price increases) identified. RESULTS: We identified 359 cases published by competition authorities in Australia (n = 202), South Africa (n = 44), the US (n = 27), and the EU (n = 86). Most cases (n = 239) related to mergers and acquisitions (M&As). Competition authorities in Australia, the US, and the EU were found to make many decisions oriented towards increasing the affordability and accessibility of alcohol beverages, soft drinks, and tobacco products. Such decisions were very often made despite the presence of consumption-reduction public health policies. In comparison, South Africa's competition authorities routinely considered broader issues, including 'Black Economic Empowerment' and potential harms to workers. CONCLUSION: Many of the competition regulatory decisions assessed likely facilitated the concentration of market power in the industries we explored. Nevertheless, there appears to be potential for competition regulatory frameworks to play a more prominent role in promoting and protecting the public's health through tighter regulation of excessive market power in harmful consumer product industries.
Assuntos
Competição Econômica , União Europeia , Humanos , África do Sul , Estados Unidos , Austrália , Bebidas Alcoólicas , Bebidas Gaseificadas , Indústria do Tabaco/legislação & jurisprudência , Saúde Pública/legislação & jurisprudência , Tomada de Decisões , Análise DocumentalRESUMO
Misinformation surrounding crises poses a significant challenge for public institutions. Understanding the relative effectiveness of different types of interventions to counter misinformation, and which segments of the population are most and least receptive to them, is crucial. We conducted a preregistered online experiment involving 5228 participants from Germany, Greece, Ireland, and Poland. Participants were exposed to misinformation on climate change or COVID-19. In addition, they were pre-emptively exposed to a prebunk, warning them of commonly used misleading strategies, before encountering the misinformation, or were exposed to a debunking intervention afterwards. The source of the intervention (i.e. the European Commission) was either revealed or not. The findings show that both interventions change four variables reflecting vulnerability to misinformation in the expected direction in almost all cases, with debunks being slightly more effective than prebunks. Revealing the source of the interventions did not significantly impact their overall effectiveness. One case of undesirable effect heterogeneity was observed: debunks with revealed sources were less effective in decreasing the credibility of misinformation for people with low levels of trust in the European Union (as elicited in a post-experimental questionnaire). While our results mostly suggest that the European Commission, and possibly other public institutions, can confidently debunk and prebunk misinformation regardless of the trust level of the recipients, further evidence on this is needed.
Assuntos
COVID-19 , Comunicação , União Europeia , Confiança , Humanos , COVID-19/epidemiologia , COVID-19/prevenção & controle , Masculino , Feminino , Adulto , Polônia , Alemanha , Mudança Climática , Grécia , Inquéritos e Questionários , Irlanda , SARS-CoV-2 , Pessoa de Meia-Idade , Adulto JovemRESUMO
BACKGROUND: Cell and gene therapy products (CGTPs) often receive accelerated approvals, lacking comprehensive long-term safety and efficacy data, which can raise significant safety concerns. This research aims to study the post-marketing surveillance (PMS) of CGTPs in the European Union (EU), the United States (US), Japan, South Korea, and China, to offer insights for the development of a secure and standardized post-marketing regulatory framework for CGTPs. METHODS: Related regulations and the implementation effect of PMS for approved CGTPs were studied searching PubMed, CNKI, and the official websites of the European Medicines Agency, the US Food and Drug Administration, Japan's Pharmaceuticals and Medical Device Agency, South Korea's Ministry of Food and Drug Safety, and the National Medical Products Administration of China. RESULTS: Compared to those in China, the guidelines of PMS for CGTPs in the EU, the US, Japan, and South Korea was more comprehensive. Notably, the EU had dedicated regulations and supporting guidelines of PMS. Of the 26 CGTPs approved in the EU, 88% were under additional monitoring, 38% received conditional marketing authorization, and 12% were authorized under exceptional circumstances, with 77% designated as orphan drugs. The US had released 34 guidelines specifically for CGTPs which, forming the foundation of post-marketing risk management. Among the 27 CGTPs approved in the US, 22% were required to perform risk evaluation and mitigation strategies, 37% added black box warnings in the package inserts, 63% mandated to post-marketing requirements, and 15% subject to post-marketing commitments. In Japan, stringent supervision measures encompassing all-case surveillance (79%) and re-examination (53%) were applied to the 19 approved CGTPs, with 21% approved through conditional and time-limited approval. The PMS for CGTPs in South Korea, mainly included PSUR, re-examination, and re-evaluation. China had introduced several relevant regulations, which consisted of general statements and lacked detailed guidance. CONCLUSIONS: This study demonstrates that the regulatory policies of PMS for CGTPs in the EU, the US, Japan, and South Korea were comprehensive. The implementation of PMS for CGTPs in the EU, the US, and Japan was well developed. This knowledge holds valuable insights for China's future learning and development in this field.
Assuntos
União Europeia , Terapia Genética , Vigilância de Produtos Comercializados , China , Estados Unidos , Humanos , Japão , Terapia Genética/legislação & jurisprudência , República da Coreia , Terapia Baseada em Transplante de Células e Tecidos/métodosRESUMO
BACKGROUND: The European Health Data Space (EHDS) regulation has been proposed to harmonize health data processing. Given its parallels with the Act on Secondary Use of Health and Social Data (Secondary Use Act) implemented in Finland in 2020, this study examines the consequences of heightened privacy constraints on registry-based medical research. METHODS: We collected study permit counts approved by university hospitals in Finland in 2014-2023 and the data authority Findata in 2020â2023. The changes in the study permit counts were analysed before and after the implementation of the General Data Protection Regulation (GDPR) and the Secondary Use Act. By fitting a linear regression model, we estimated the deficit in study counts following the Secondary Use Act. RESULTS: Between 2020 and 2023, a median of 5.5% fewer data permits were approved annually by Finnish university hospitals. On the basis of linear regression modelling, we estimated a reduction of 46.9% in new data permits nationally in 2023 compared with the expected count. Similar changes were neither observed after the implementation of the GDPR nor in permit counts of other medical research types, confirming that the deficit was caused by the Secondary Use Act. CONCLUSIONS: This study highlights concerns related to data privacy laws for registry-based medical research and future patient care.
Assuntos
Pesquisa Biomédica , Confidencialidade , Sistema de Registros , Humanos , Finlândia , Segurança Computacional , Hospitais Universitários , Europa (Continente) , Privacidade , União EuropeiaRESUMO
The mycotoxin deoxynivalenol (DON) is frequently present in cereals at low levels, resulting in its occurrence in food and feed. DON has been proven to alter the immune response and induce inflammation in all species, with pigs exhibiting heightened sensitivity and exposure. However, no study has yet evaluated the effects of exposure to DON at the recommended levels in pig feed. In two separate trials, piglets were subjected to control feed or feed contaminated with a low level of purified DON (0.83 mg/kg feed in trial 1 and 0.85 mg/kg feed in trial 2) for either three weeks (trial 1) or two weeks (trial 2). Additionally, a group of animals exposed to 2.85 mg/kg feed of DON was included as a positive control in Trial 1. The impact of DON on porcine tissues (intestine, liver, and spleen) was evaluated through histological and qPCR analyses of immune-related genes. Additionally, biochemical analyses and acute-phase proteins were examined in plasma samples. Lesions were identified in the intestine (jejunum and ileum), the liver, and the spleen of pigs receiving diets contaminated with low and high concentrations of DON. The low level of DON also resulted in impaired expression of genes associated with intestinal barrier integrity, intestinal immune responses, and liver function. In conclusion, the results of the two trials demonstrate the impact of DON exposure even at doses below the recommended level of 0.9 mg/kg feed set by the European Union. This suggests that the current recommended level should be reconsidered to ensure the optimal health and well-being of pigs.
Assuntos
Ração Animal , União Europeia , Inflamação , Fígado , Tricotecenos , Tricotecenos/toxicidade , Animais , Suínos , Inflamação/induzido quimicamente , Fígado/efeitos dos fármacos , Fígado/metabolismo , Fígado/patologia , Contaminação de Alimentos/análise , Baço/efeitos dos fármacos , Baço/metabolismo , Baço/patologiaRESUMO
Technological and scientific innovations in the area of gene and cell therapies, so-called advanced therapy medicinal products (ATMPs), have contributed to the steep increase in treatment options for patients with rare diseases. They offer opportunities to address the underlying genetic defect by gene addition, i.e., the delivery of the gene of interest to the target cells, or by genome editing approaches through direct repair of disease-causing mutations. This paper outlines clinical evidence requirements in the context of marketing authorisations for rare diseases. Two out of fifteen gene therapies that have been approved in the European Union since 2018 are used as case studies: Libmeldy (atidarsagen autotemcel) for the treatment of patients with metachromatic leukodystrophy, and Roctavian (valoctocogen roxaparvovec) for the treatment of patients with haemophilia A. Special aspects of the evaluation of single-arm trials with small sample size and requirements with regard to the isolation and causal attribution of the treatment effect are discussed. The role of clinical data obtained under everyday conditions (real world data) to support the generation of evidence in the pre- and post authorisation phase is critically examined. Furthermore, the paper outlines aspects related to conditional versus standard marketing authorisations as well as aspects related to registry-based non-interventional studies in the context of market and patient access to urgently needed drugs.
Assuntos
Terapia Baseada em Transplante de Células e Tecidos , União Europeia , Terapia Genética , Doenças Raras , Doenças Raras/terapia , Doenças Raras/genética , Terapia Genética/legislação & jurisprudência , Humanos , Marketing de Serviços de Saúde/legislação & jurisprudência , Europa (Continente) , Medicina Baseada em EvidênciasRESUMO
Background: Public tenders are vital for a country's GDP and citizens' quality of life, enabling public administration to achieve various goals. Developing and developed countries allocate over 10% of their GDP to public procurement. This highlights the significant societal support public tenders can provide, making it important to consider how they can further benefit society. Policy and implications: Public procurement can achieve policy objectives and benefit society by selecting tenders based on criteria beyond price, such as economic advantage and social benefits. This approach, endorsed by EU directives since 2014, encourages innovation and socially responsible practices. Contracting authorities in the EU can use social, environmental, and qualitative criteria to determine the most advantageous offers.Poland's Public Procurement Law (PPL) allows contract award criteria based on quality and price, including social aspects. Contracting authorities can specify criteria like employing marginalized groups, though these criteria often face scrutiny and legal challenges. Non-price criteria aim to enhance competition and achieve social, environmental, and economic goals. Recommendations: EU and Polish laws permit and encourage using social aspects as contract award criteria in public procurement. However, contracting authorities must analyze priorities, risk balancing, time constraints, and departmental coordination to effectively implement these criteria. This approach can improve the social situation and support specific groups. Conclusions: Public procurement significantly influences a country's economy and quality of life, with EU and Polish laws allowing social criteria in contract awards. Directive 2014/24/EU supports tenders based on economic and social benefits. Poland's PPL aligns with this, emphasizing marginalized group employment. Effective implementation fosters job creation, social integration, and improved living standards.
Assuntos
União Europeia , Polônia , Humanos , Contratos/legislação & jurisprudênciaRESUMO
The EU AI Act, the first comprehensive regulation of AI, came into effect in August. Here, we provide an overview of the provisions that apply to the field of neurotechnology with respect to research and development and neuroscience practice and discuss some implications for the future.
Assuntos
Inteligência Artificial , União Europeia , Neurociências , Neurociências/legislação & jurisprudência , HumanosRESUMO
Fossil and mineral raw materials cause unintended and detrimental environmental and social impacts via extraction, production and combustion processes. In this study, we analyse how consumer demand in the European Union (EU) drives environmental and social impacts in mining sectors worldwide. We employ multi-regional input-output analysis to quantify positive (i.e., income, female and male employment) and negative (greenhouse gas emissions, accidents at work, and modern slavery) impacts of raw materials. We trace these environmental and social impacts across the EU's trading partners to identify sectoral and regional hotspots of international spillovers embodied in the EU's consumer demand. We estimate that the EU's consumption is associated with significant spillover impacts primarily in Central Asia, Asia Pacific, and Africa. We contextualise these results within a three-pillar framework to highlight the importance of a comprehensive and partnership-based approach to curbing environmental and social spillovers embodied in the EU's consumption of raw materials. Specifically, we highlight three potential practical policy strategies: leveraging EU domestic instruments and regulations, strengthening the Green Deal and SDG diplomacy and financing, and promoting responsible consumption, recycling and innovation. Our results underline the need for further reforms in mining industries and trade policies to reduce adverse social and environmental impacts.
Assuntos
União Europeia , Minerais , Carbono/análise , Fósseis , Reciclagem , Mineração , Meio AmbienteRESUMO
This study examines the spillover of pollution among the 26 European Union (EU) countries from 1995 to 2020. In order to quantify pollution spillovers among the countries, we estimated the Environmental Kuznets Curve (EKC) using spatial econometric methods. Our research is unique in that it investigates ecological footprint spillovers for EU countries. This study also considers the direct and indirect effects of renewable and fossil energy consumption and globalization on environmental degradation in EU countries. The empirical results favor the validity of the EKC hypothesis. Our results support the presence of positive and significant ecological footprint spillovers among EU countries. Our spatial estimates also reveal the significant spillover impact of explanatory variables on the ecological footprint. The ecological footprint of the local country is declining owing to the consumption of renewable energy in neighboring countries. Furthermore, the fossil energy consumption of the local and neighboring countries has a positive impact on the ecological footprint. Evidence obtained from our spatial estimates provides useful insights to policymakers in developing appropriate environmental policies to combat climate change.
Assuntos
União Europeia , Combustíveis Fósseis , Energia Renovável , Mudança Climática , Poluição AmbientalRESUMO
The circular economy has been identified as a critical keyword for achieving the Sustainable Development Goals. Nevertheless, there is a lack of in-depth empirical literature on the impact mechanisms of the circular economy (CE) and economic growth (GDP) in mitigating e-waste generation (waste electrical and electronic equipment - WEEE). Given Europe's leading position in e-waste generation per capita, the study aims to scrutinize the interplay between CE, GDP, and WEEE for 2010-2020. The research applies advanced econometric methods, primarily centered around the system generalized method of moment and dynamic panel threshold. It was noteworthy that different CE indicators exhibited varying effects on WEEE through the econometric analysis. Therefore, the research uniquely utilized the entropy weight method to compute a holistic composite index for the circular economy (CEI) and gained some interesting findings. Firstly, CEI significantly reduced WEEE, while GDP drove its increase. However, an overly developed CEI of 0.7616 counteracted its beneficial effect. Secondly, the synergy of CEI*GDP engendered the circular economy rebound effect, diminishing environmental benefits. Thirdly, in the circular context, the environmental Kuznets curve was validated, showcasing an inverted U-shaped pattern. Finally, the study found CEI to have different threshold effects, with thresholds of 0.2161 to inhibit WEEE, 0.2114 to avert the circular economy rebound effect, and 0.2360 to leverage GDP in reducing WEEE. These outcomes give insights to policymakers in designing sound policies targeting circular economy development and decoupling e-waste generation from economic growth towards the United Nations' SDGs.
Assuntos
Desenvolvimento Econômico , Resíduo Eletrônico , União Europeia , Desenvolvimento Sustentável , Europa (Continente)RESUMO
Life expectancy is one of the primary population health indicators and in turn increases in life expectancy indicate improvements in population health and human welfare. Therefore, one of the ultimate goals of the countries is to increase the life expectancy. This article studies the effect of education and income inequalities, ICT indicators, CO2 emissions, and real GDP per capita on life expectancy in the new EU members for the period of 2010-2022 by employing fixed effects regression. The coefficients of panel regression uncover that education and income inequalities and CO2 emissions negatively impact life expectancy, but ICT indicators of internet usage and mobile cellular subscriptions and real GDP per capita positively affects the life expectancy. The findings of the panel regression analysis indicate that public policies to decrease the inequalities in education and income will make a contribution to life expectancy.
Assuntos
Escolaridade , Renda , Expectativa de Vida , Fatores Socioeconômicos , Expectativa de Vida/tendências , Humanos , Renda/estatística & dados numéricos , Masculino , Feminino , União Europeia/estatística & dados numéricos , Idoso , Pessoa de Meia-IdadeRESUMO
While more and more health-related data is being produced and published every day, few of it is being prepared in a way that would be beneficial for daily use outside the scientific realm. Interactive visualizations that can slice and condense enormous amounts of multi-dimensional data into easy-to-digest portions are a promising tool that has been under-utilized for health-related topics. Here we present two case studies for how interactive maps can be utilized to make raw health data accessible to different target audiences: i) the European Notifiable Diseases Interactive Geovisualization (ENDIG) which aims to communicate the implementation status of disease surveillance systems across the European Union to public health experts and decision makers, and ii) the Zoonotic Infection Risk in Twente-Achterhoek Map (ZIRTA map), which aims to communicate information about zoonotic diseases and their regional occurrence to general practitioners and other healthcare providers tasked with diagnosing infectious diseases on a daily basis. With these two examples, we demonstrate that relatively straight-forward interactive visualization approaches that are already widely used elsewhere can be of benefit for the realm of public health.
Assuntos
Zoonoses , Humanos , Zoonoses/epidemiologia , Animais , Análise Espaço-Temporal , Saúde Pública , Pessoal de Saúde , União Europeia , Mapeamento Geográfico , Vigilância da População/métodos , Disseminação de Informação , Sistemas de Informação GeográficaRESUMO
BackgroundInfluenza viruses can cause large seasonal epidemics with high healthcare impact and severity as they continually change their virological properties such as genetic makeup over time.AimWe aimed to monitor the characteristics of circulating influenza viruses over the 2022/23 influenza season in the EU/EEA countries. In addition, we wanted to compare how closely the circulating viruses resemble the viral components selected for seasonal influenza vaccines, and whether the circulating viruses had acquired resistance to commonly used antiviral drugs.MethodsWe performed a descriptive analysis of the influenza virus detections and characterisations reported by National Influenza Centres (NIC) from the 30 EU/EEA countries from week 40/2022 to week 39/2023 to The European Surveillance System (TESSy) as part of the Global Influenza Surveillance and Response System (GISRS).ResultsIn the EU/EEA countries, the 2022/23 influenza season was characterised by co-circulation of A(H1N1)pdm09, A(H3N2) and B/Victoria-lineage viruses. The genetic evolution of these viruses continued and clade 6B.1A.5a.2a of A(H1N1)pdm09, 3C.2a1b.2a.2b of A(H3N2) and V1A.3a.2 of B/Victoria viruses dominated. Influenza B/Yamagata-lineage viruses were not reported.DiscussionThe World Health Organization (WHO) vaccine composition recommendation for the northern hemisphere 2023/24 season reflects the European virus evolution, with a change of the A(H1N1)pdm09 component, while keeping the A(H3N2) and B/Victoria-lineage components unchanged.
Assuntos
Vírus da Influenza A Subtipo H1N1 , Vírus da Influenza A Subtipo H3N2 , Vírus da Influenza B , Vacinas contra Influenza , Influenza Humana , Estações do Ano , Influenza Humana/virologia , Influenza Humana/epidemiologia , Humanos , Vírus da Influenza A Subtipo H3N2/genética , Vírus da Influenza A Subtipo H3N2/isolamento & purificação , Vírus da Influenza A Subtipo H1N1/genética , Vírus da Influenza A Subtipo H1N1/isolamento & purificação , Vírus da Influenza B/genética , Vírus da Influenza B/isolamento & purificação , Europa (Continente)/epidemiologia , Vacinas contra Influenza/administração & dosagem , Vacinas contra Influenza/imunologia , Filogenia , Antivirais/uso terapêutico , Vigilância da População , Variação Genética , União EuropeiaRESUMO
This article investigates the pivotal role of non-hazardous waste landfills in achieving greenhouse gas (GHG) reduction objectives within the European Union (EU).1 This study leverages the experience of key stakeholders in the European landfilling, assesses the efficacy of 'best-in-class' landfill installations, evaluates their potential impact on GHG reduction, and offers concrete recommendations for operators and policymakers. 'Best-in-class' landfills exceed the commonly accepted best practices by implementing all the following practices: (1) an anticipated capture system during the operating phase, (2) prompt installation of the final cover and capture system, with use of an impermeable cover, (3) operated as bioreactor, keeping optimal humidity, (4) adequate maintenance and reporting, (5) recovery of captured gas and (6) treatment of residual methane emissions throughout the waste decomposition process. The main finding is that switching from the actual mix of practices to 'best in class' practices would reduce by ~21 MtCO2eq (-36%) the emissions due to the degradation of waste landfilled between 2024 and 2035, compared to the 'business-as-usual scenario', while also providing a renewable energy source, bringing potential avoided emissions and energy sovereignty. The findings underscore that in addition to implementing the organics diversion and waste reduction targets of the EU, adopting 'best-in class' landfill practices has the potential to bolster energy recovery, mitigate emissions and stimulate biomethane production, thereby advancing the EU environmental goals.
Assuntos
União Europeia , Gases de Efeito Estufa , Instalações de Eliminação de Resíduos , Gases de Efeito Estufa/análise , Metano/análise , Gerenciamento de Resíduos/métodos , Eliminação de Resíduos/métodos , Poluição do Ar/prevenção & controle , Política Ambiental , Poluentes Atmosféricos/análiseRESUMO
Despite increasing contestations of agreed global commitments on sexual and reproductive health and rights (SRHR), our understanding of strategies of opposition in global health policymaking remains limited. This article explores the opposition to SRHR at the European level focusing on the decision-making institutions of the European Union (EU). The central research questions ask i) how SRHR opposition actors seek to influence EU institutions and ii) what challenges their actions pose for health policymaking at the EU level. Our empirical focus is based on the qualitative method of framework analysis, with data collected from multiple sources, including documentary data on European Parliamentary debates, Council conclusions of the European Union, reports of nongovernmental organisations, and key informant interviews. Our study is in line with observations on globally coordinated efforts to restrict access to SRH services. This is a challenge for specific forums and countries, but as well for European Union's wider internal and external policies. We present a toolbox of strategies and actors operational at the European Union level. Our findings on opposition to SRHR indicate that it can be seen as a political tool that is part of a broader anti-democratic movement. Understanding strategies of anti-SRHR opposition is important for health policymakers as it shapes debates and the achievement of universal health coverage (UHC).
Assuntos
Democracia , União Europeia , Pesquisa Qualitativa , Saúde Reprodutiva , Humanos , Política , Política de Saúde , Formulação de Políticas , Direitos Sexuais e ReprodutivosRESUMO
Cow-calf systems represent a significant research area in animal husbandry, with differences depending on the final product (meat or milk). This study aimed to apply text mining and topic analysis on literature describing cow-calf systems in European, American, and Brazilian beef and dairy sectors between 1998 and 2023. Additionally, cow-calf contact (CCC) literature data was manually extracted. Our findings revealed the presence of 11 research areas among literature on cow-calf systems, with different priorities identified in the beef and dairy sectors. Beef industry mainly focused on animal proficiency and nutrition, while dairy on animal welfare and CCC, which showed a growing trend as emerging research topic, mostly in the EU. Current debates around calf welfare and EU's planned animal welfare legislation revision appeared to be driving the increasing interest in this topic. Studies in the beef sector were mainly localized in Brazil, showing that research in different contexts and species is important for CCC implementation. Manual data extraction showed considerable variation in the retained CCC documents regarding sample size, type of contact, methods and CCC duration. Learning about the varied CCC approaches used in beef and dairy farms in different locations, concentrating on their strengths and weaknesses, will help to develop novel solutions to global challenges. Adopting validated and robust indicators would help scientists and policymakers to monitor the system's quality. To improve CCC feasibility, match consumer demands, and move towards One Welfare and One Health, future research should focus on a variety of situations to overcome the current shortcomings.