RESUMO
BACKGROUND: Phuket Province is a major tourist destination with a migrant workforce accounting for 10% of its population. Despite governmental efforts to adjust health insurance policies, migrants face healthcare access challenges. This study examines the current healthcare access situation and factors associated with unmet needs among migrants in Phuket Province. METHODS: We used a cross-sectional mixed-methods approach, recruiting participants through snowball sampling from the Migrant Health Volunteer Network. Quantitative data were gathered using self-administered questionnaires, with unmet need defined as desired outpatient or recommended inpatient services not received at government hospitals. Multivariable logistic regression identified unmet need predictors, and we assessed the mediating effect of health insurance status. Qualitative data from three focus groups on healthcare access provided context and enriched the quantitative findings. RESULTS: This study includes 296 migrants mainly from Myanmar. The overall unmet need prevalence was 14.86%, mainly attributed to having undocumented status (34.09%), affordability issues (20.45%), and language barriers (18.18%). Working in the fishery industry significantly increased unmet needs risk (aOR 2.68, 95% CI 1.08-6.62). Undocumented status contributed a marginal total effect of 4.86 (95% CI 1.62-14.54), with a natural indirect effect through uninsured status of only 1.16 (95% CI 0.88-1.52). Focus group participants used various medical resources, with insured individuals preferring hospital care, but faced obstacles due to undocumented status and language barriers. CONCLUSION: Valid legal documents, including work permits and visas, are crucial for healthcare access. Attention to fishery industry practices is needed. We recommend stakeholder discussions to streamline the process of obtaining and maintaining these documents for migrant workers. These improvements could enhance health insurance acquisition and ultimately improve healthcare affordability for this population. These insights could be applied to migrant workers in other urban and suburban area of Thailand regarding access to government healthcare facilities.
Assuntos
Acessibilidade aos Serviços de Saúde , Necessidades e Demandas de Serviços de Saúde , Migrantes , Humanos , Estudos Transversais , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Feminino , Migrantes/estatística & dados numéricos , Tailândia , Masculino , Adulto , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Pessoa de Meia-Idade , Inquéritos e Questionários , Grupos Focais , Seguro Saúde/estatística & dados numéricos , Cobertura do Seguro/estatística & dados numéricosRESUMO
Hyperspectral imaging has emerged as a powerful tool for the non-destructive assessment of plant properties, including the quantification of phytochemical contents. Traditional methods for antioxidant analysis in holy basil (Ocimum tenuiflorum L.) are time-consuming, while hyperspectral imaging has the potential to rapidly observe holy basil. In this study, we employed hyperspectral imaging combined with machine learning techniques to determine the levels of total phenolic contents in Thai holy basil. Spectral data were acquired from 26 holy basil cultivars at different growth stages, and the total phenolic contents of the samples were measured. To extract the characteristics of the spectral data, we used 22 statistical features in both time and frequency domains. Relevant features were selected and combined with the corresponding total phenolic content values to develop a neural network model for classifying the phenolic content levels into 'low' and 'normal-to-high' categories. The neural network model demonstrated high performance, achieving an area under the receiver operating characteristic curve of 0.8113, highlighting its effectiveness in predicting phenolic content levels based on the spectral data. Comparative analysis with other machine learning techniques confirmed the superior performance of the neural network approach. Further investigation revealed that the model exhibited increased confidence in predicting the phenolic content levels of older holy basil samples. This study exhibits the potential of integrating hyperspectral imaging, feature extraction, and machine learning techniques for the rapid and non-destructive assessment of phenolic content levels in holy basil. The demonstrated effectiveness of this approach opens new possibilities for screening antioxidant properties in plants, facilitating efficient decision-making processes for researchers based on comprehensive spectral data.
Assuntos
Aprendizado de Máquina , Fenóis , Fenóis/análise , Redes Neurais de Computação , Ocimum basilicum/química , Imageamento Hiperespectral/métodos , Tailândia , Antioxidantes/análise , Análise de Dados , População do Sudeste AsiáticoRESUMO
Eastern Thailand and Rayong province face perennial drought and water scarcity due to natural characteristics of climate and geology. Therefore, increasing water surface by man-made reservoirs is one of the priorities in the regional development plan to provide water adequately for industrial purposes, domestic consumption, and agriculture. The large reservoir constructions may induce land use, land cover changes (LULCC), yet it also is expected to alleviate the drought harshness in the region. By delineating Landsat satellite images and spatial analysis, this study revealed the LULCC in Rayong from 1990 to 2020. The most prominent LULCC was surface water expansion, about 10.9% per year, yet the increase was the most substantial in the first decade rather than the last two decades. Vegetation expansion was observed, contributing to an increase in forests/plantations and intensified agriculture by 39.19% and 25.54%, respectively. The LULCC corresponded to a 3.64% increase in ecosystem service values (ESV), implying positive benefits from the LULCC. Vegetation drought conditions monitored by the vegetation health index (VHI) exhibited an improvement trend, especially in the eastern basins. The development of artificial reservoirs was proven to stimulate the expansion of intensive agriculture and vegetation drought mitigation with spatial heterogeneity, spreading mainly across areas of the basins rather than remote areas. The research findings inform the efficiency of the reservoirs and irrigation systems regarding the beneficial effects on drought mitigation and water scarcity for agricultural cultivation. They also provide spatial information on areas still hindered by water problems that should be addressed in future strategies.
Assuntos
Agricultura , Conservação dos Recursos Naturais , Secas , Monitoramento Ambiental , Tailândia , Agricultura/métodos , Conservação dos Recursos Naturais/métodos , Abastecimento de Água , Ecossistema , FlorestasRESUMO
This study systematically examines the patterns of milk yield (MY, kg), fat (FAT, %), and protein (PROT, %) in a diverse population of Thai multibreed dairy cattle, considering the tropical environment's impact on lactating cows. Using a dataset of 47,205 monthly test-day records from 4,440 first-lactation cows across 446 farms, we analyze variations and interrelationships through mathematical averaging and introduce the fat-to-protein ratio (FPR) to assess acidosis (FPR < 1.1) and ketosis (FPR > 1.5) risks during lactation. Pearson correlation analysis elucidated trait associations. The findings, aligned with established lactation norms, indicate peak production at 297 days in milk (DIM) for FAT (4.08%; SD = 0.96%), PROT (3.43%; SD = 0.47%), and 52 DIM for MY (18.09 kg; SD = 4.91 kg). Nadirs are observed at 72 DIM for FAT (3.27%; SD = 0.74%), 47 DIM for PROT (2.86%; SD = 0.36%), and 299 DIM for MY (9.05 kg; SD = 2.95 kg). FPR variations highlight acidosis (46.48%), normal (43.66%), and ketosis (9.86%), especially during early lactation (100 DIM). Significant negative correlations emerge between MY, FAT, and PROT (P < 0.05), while a positive correlation is identified between FAT and PROT (P < 0.01), with robust correlations during early lactation. This study contributes to understanding tailored nutritional strategies for dairy cows' holistic health and sustainability in tropical environments, guiding efficient production practices and mitigating health-related productivity impediments.
Assuntos
Lactação , Leite , Animais , Bovinos/fisiologia , Tailândia , Lactação/fisiologia , Feminino , Leite/química , Leite/metabolismo , Proteínas do Leite/análise , Gorduras/análise , Gorduras/metabolismo , Cetose/veterinária , Doenças dos Bovinos , Indústria de Laticínios , Acidose/veterinária , População do Sudeste AsiáticoRESUMO
BACKGROUND: Drowning remains a common cause of death among children. However, the epidemiology and impact of drowning in Thailand was underexplored. This study aimed to analyze the epidemiology and clinical outcomes of pediatric drowning in Thailand and to determine the factors associated with the need for intubation and mortality. METHODS: Data derived from the Thai healthcare delivery system for the period between 2015 and 2019 were used to examine the monthly admissions, mortality rates, length of hospital stay, and the number of patients who received endotracheal intubation. Multivariate logistic regression analysis was employed to identify the risk factors associated with the need for intubation and mortality. RESULTS: Of the 4,911, 58.8% were under six years old, 63.5% were male, and 31.2% were from the Northeastern region. The majority drowned during April, which is the summer season in Thailand. Among these patients, 28.8% required intubation, with the highest proportion found in the 6-<12 years age group (35.9%). The independent risk factors for intubation were metabolic acidosis (adjusted odd ratio [aOR] 9.74; 95% confidence interval [CI] 7.14-13.29; p < 0.001) and pulmonary edema (aOR 5.82; 95%CI 3.92-8.65; p < 0.001). The overall mortality rate due to drowning was 12.6%. Factors significantly associated with mortality included in-hospital cardiac arrest (aOR 4.43; 95%CI 2.78-7.06; p < 0.001), and the presence of drowning-related complications, particularly renal failure (aOR 7.13; 95%CI 3.93-12.94; p < 0.001). CONCLUSION: Drowning admissions and mortality were highest among male children under six years old, occurring mainly during the summer season. Significant factors associated with intubation requirement included metabolic acidosis and pulmonary edema. The mortality was significantly associated with in-hospital cardiac arrest and drowning-related complications, particularly renal failure. TRIAL REGISTRATION: This is an observational study, does not include any intervention, and has therefore not been registered.
Assuntos
Afogamento , Humanos , Tailândia/epidemiologia , Masculino , Feminino , Criança , Pré-Escolar , Afogamento/epidemiologia , Afogamento/mortalidade , Lactente , Fatores de Risco , Hospitalização/estatística & dados numéricos , Intubação Intratraqueal/estatística & dados numéricos , Adolescente , Mortalidade Hospitalar/tendências , Tempo de Internação/estatística & dados numéricos , Estudos Retrospectivos , População do Sudeste AsiáticoRESUMO
The distribution of farm locations and sizes is paramount to characterize patterns of disease spread. With some regions undergoing rapid intensification of livestock production, resulting in increased clustering of farms in peri-urban areas, measuring changes in the spatial distribution of farms is crucial to design effective interventions. However, those data are not available in many countries, their generation being resource-intensive. Here, we develop a farm distribution model (FDM), which allows the prediction of locations and sizes of poultry farms in countries with scarce data. The model combines (i) a Log-Gaussian Cox process model to simulate the farm distribution as a spatial Poisson point process, and (ii) a random forest model to simulate farm sizes (i.e. the number of animals per farm). Spatial predictors were used to calibrate the FDM on intensive broiler and layer farm distributions in Bangladesh, Gujarat (Indian state) and Thailand. The FDM yielded realistic farm distributions in terms of spatial clustering, farm locations and sizes, while providing insights on the factors influencing these distributions. Finally, we illustrate the relevance of modelling realistic farm distributions in the context of epidemic spread by simulating pathogen transmission on an array of spatial distributions of farms. We found that farm distributions generated from the FDM yielded spreading patterns consistent with simulations using observed data, while random point patterns underestimated the probability of large outbreaks. Indeed, spatial clustering increases vulnerability to epidemics, highlighting the need to account for it in epidemiological modelling studies. As the FDM maintains a realistic distribution of farm location and sizes, its use to inform mathematical models of disease transmission is particularly relevant for regions where these data are not available.
Assuntos
Fazendas , Gado , Doenças das Aves Domésticas , Aves Domésticas , Animais , Fazendas/estatística & dados numéricos , Doenças das Aves Domésticas/epidemiologia , Doenças das Aves Domésticas/transmissão , Criação de Animais Domésticos/métodos , Criação de Animais Domésticos/estatística & dados numéricos , Galinhas , Análise Espacial , Tailândia/epidemiologia , Biologia Computacional , Bangladesh/epidemiologia , Simulação por Computador , Modelos EstatísticosRESUMO
BACKGROUND: Radiofrequency ablation (RFA) is a common secondary treatment recommended for facet joint-related chronic low back pain (CLBP). However, Thailand still lacks sufficient evidence of RFA's cost-effectiveness to support the decision to fund it. OBJECTIVE: To conduct a comparative economic evaluation of RFA and conservative treatment for CLBP patients over 16-month and 28-month time horizons in Thailand. STUDY DESIGN: A full economic evaluation encompassing measurements of both health utilities and health costs. SETTING: Data were collected from 3 university hospitals in Bangkok, Thailand: King Chulalongkorn Memorial Hospital, Siriraj Hospital, and Ramathibodi Hospital. METHODS: The cost-utility analysis, which used the Markov model, was developed according to the Thai health technology assessment guidelines and compared RFA and the best supportive care from the societal perspective. In the study, the population consisted of patients who had endured low back pain for more than 3 months despite receiving conservative treatment. The results were presented as an incremental cost-effective ratio (ICER) in Thai Baht (THB)/quality-adjusted life year (QALY). Scenario and sensitivity analyses were conducted. RESULTS: RFA was not cost-effective in Thailand when compared to conservative treatment, with a cost-effectiveness (CE) ratio of I$13,652 at all time horizons. The ICER of RFA was I$99,267 and I$52,380/QALY for the 16- and 28-month time horizons, respectively. In a scenario analysis in which RFA was repeated at 28 months and followed up to 52 months, the ICER was reduced to I$43,451. One-way sensitivity analysis showed that the ICER was most sensitive to the changes in utility parameters, the cost of RFA, and opportunity cost in the no-pain state. LIMITATIONS: The study uses primary data to derive the utility value and determine the costs. However, the limitation includes a relatively small sample size and a short follow-up time for parameter inputs. CONCLUSION: This study, the first economic evaluation of RFA for CLBP in Asia, showed that RFA was not cost-effective in Thailand. Price negotiation is recommended to make the intervention more cost-effective before it is included in the benefit package.
Assuntos
Análise Custo-Benefício , Dor Lombar , Anos de Vida Ajustados por Qualidade de Vida , Articulação Zigapofisária , Humanos , Dor Lombar/economia , Dor Lombar/cirurgia , Dor Lombar/terapia , Tailândia , Articulação Zigapofisária/cirurgia , Ablação por Radiofrequência/economia , Ablação por Radiofrequência/métodos , Feminino , Masculino , Pessoa de Meia-Idade , Dor Crônica/economia , Dor Crônica/terapiaRESUMO
Japanese encephalitis (JE) is a significant public health concern in Asia, particularly in children, where vaccination plays a crucial role in prevention. In this study, we investigated the immunogenicity and safety of two different live-attenuated JE vaccines used as primary and booster doses. Fifty healthy participants aged 1-3 years, who were primed with the chimeric JE vaccine IMOJEV® a year earlier, received a booster dose of the SA14-14-2 JE vaccine CD.JEVAX®. To evaluate the immune response, JE-neutralizing antibody titers were assessed on day 0 (pre-booster), day 30, and annually from 1 to 5 years post-booster using the 50% plaque reduction neutralization test (JEPRNT50). The assessment revealed strong immunogenicity 30 d post-booster, with a geometric mean titer of 2092.4 [95% confidence interval (CI): 1473.9-2970.5] and a seroprotection rate of 100%, which gradually decreased to 97.5% at 5 years post-booster. No severe adverse events were observed. The most common reaction within 7 d of vaccination was fever (20%; 95% CI: 10.7-32.3). These results indicate that a booster dose of CD.JEVAX® elicits a strong immune response in children previously vaccinated with IMOJEV® while maintaining a good safety profile, thus supporting the interchangeability of these two live-attenuated JE vaccines. Registered at www.thaiclinicaltrials.org (TCTR ID: TCTR20221102003), our study suggests that CD.JEVAX® can be a viable option for booster vaccination in JE prevention programs, potentially enhancing vaccine flexibility and accessibility.
Assuntos
Anticorpos Neutralizantes , Anticorpos Antivirais , Encefalite Japonesa , Imunização Secundária , Vacinas contra Encefalite Japonesa , Vacinas Atenuadas , Humanos , Vacinas contra Encefalite Japonesa/imunologia , Vacinas contra Encefalite Japonesa/administração & dosagem , Vacinas contra Encefalite Japonesa/efeitos adversos , Masculino , Feminino , Encefalite Japonesa/prevenção & controle , Encefalite Japonesa/imunologia , Pré-Escolar , Imunização Secundária/métodos , Lactente , Anticorpos Antivirais/sangue , Tailândia , Anticorpos Neutralizantes/sangue , Vacinas Atenuadas/imunologia , Vacinas Atenuadas/administração & dosagem , Vacinas Atenuadas/efeitos adversos , Testes de Neutralização , Imunogenicidade da Vacina , População do Sudeste AsiáticoRESUMO
This study aimed to investigate the occurrence of larval trematode infections in bithyniid snails across five provinces in southern Thailand. A total of 1,413 Bithynia siamensis snails were collected between October 2021 and October 2022 using handpicking and scooping methods. Among these, 844 were identified as B. s. siamensis and 569 as B. s. goniomphalos. The snail samples were examined for parasitic infections in the laboratory using shedding and crushing methods. Among the 27 sampling sites, snails from 6 sites were infected with various trematode species (infection rate: 4.95%, 70/1,413). Evaluation of the morphological and internal organ characteristics of the cercariae allowed for the categorization of the trematodes into five species of trematodes (belonging to four families). The identified species included Echinochasmus pelecani (family: Echinostomatidae), Echinostoma revolutum (family: Echinostomatidae), Haematoloechus similis (family: Haematoloechidae), Loxogenoides bicolor (family Lecithodendriidae), and Stictodora tridactyla (family: Heterophyidae), and the infection rates for these species were 3.26% (46/1,413), 0.35% (5/1,413), 0.42% (6/1,413), 0.78% (11/1,413), and 0.14% (2/1,413), respectively. The cercariae from the identified trematode species were studied for DNA analysis. The phylogenetic lineage reveals relationships among the species, confirming the morphological distinctions.
Assuntos
Caramujos , Trematódeos , Animais , Tailândia/epidemiologia , Trematódeos/classificação , Trematódeos/isolamento & purificação , Trematódeos/genética , Trematódeos/anatomia & histologia , Caramujos/parasitologia , Prevalência , Filogenia , Cercárias/classificação , Cercárias/isolamento & purificação , Infecções por Trematódeos/epidemiologia , Infecções por Trematódeos/parasitologia , Infecções por Trematódeos/veterináriaRESUMO
BACKGROUND: The COVID-19 pandemic disrupted routine health care and antenatal and birth services globally. The Shoklo Malaria Research Unit (SMRU) based at the Thailand-Myanmar border provides cross border antenatal care (ANC) and birth services to marginalised pregnant women. The border between the countries entered lockdown in March 2020 preventing cross-border access for women from Myanmar to Thailand. SMRU adapted by opening a new clinic during the COVID-19 pandemic in Myanmar. This study explored the impact of the COVID-19 pandemic and response on access to ANC and pregnancy outcomes for marginalised pregnant women in the border regions between Thailand and Myanmar. METHODS: A retrospective review of medical records of all pregnancies delivered or followed at antenatal clinics of the SMRU from 2017 to the end of 2022. Logistic regression was done to compare the odds of maternal and neonatal outcomes between women who delivered pre-COVID (2017-2019) and women who delivered in the COVID-19 pandemic (2020-2022), grouped by reported country of residence: Thailand or Myanmar. RESULTS: Between 2017 and the end of 2022, there were 13,865 (5,576 resident in Thailand and 8,276 in Myanmar) marginalised pregnant women who followed ANC or gave birth at SMRU clinics. Outcomes of pregnancy were known for 9,748 women with an EGA ≥ 28 weeks. Unknown outcome of pregnancy among women living in Thailand did not increase during the pandemic. However, there was a high (60%) but transient increase in unknown outcome of pregnancy for women with Myanmar residence in March 2020 following border closure and decreasing back to the baseline of 20-30% after establishment of a new clinic. Non-literate women were more likely to have an unknown outcome during the pandemic. There was no statistically significant increase in known stillbirths or maternal deaths during the COVID pandemic in this population but homebirth was over represented in maternal and perinatal mortality. CONCLUSION: Decreasing barriers to healthcare for marginalised pregnant women on the Thailand-Myanmar border by establishment of a new clinic was possible in response to sudden border closure during the COVID-19 pandemic and most likely preventing an increase in maternal and perinatal mortality.
Assuntos
COVID-19 , Resultado da Gravidez , Cuidado Pré-Natal , Humanos , Feminino , Gravidez , COVID-19/epidemiologia , COVID-19/prevenção & controle , Mianmar/epidemiologia , Tailândia/epidemiologia , Estudos Retrospectivos , Adulto , Cuidado Pré-Natal/estatística & dados numéricos , Resultado da Gravidez/epidemiologia , Recém-Nascido , SARS-CoV-2 , Adulto Jovem , Acessibilidade aos Serviços de Saúde/estatística & dados numéricosRESUMO
This study investigated the effects of age and sex on carcass and meat characteristics of one of Thailand's major indigenous chicken breeds, the white-tailed yellow native chicken (NC). A total of 120 one-day-old NC (60 males and 60 females) were raised, and harvested at either 16, 20 or 24 weeks. The results showed that body, carcass, breast and fillet weights did not differ (P > 0.05) between 16- and 20-week-old NC, but were lower (P < 0.05) than those of 24-week-old NC. Male NC had higher (P < 0.05) body, carcass, wing, back and thigh weights than female NC. Neither sex nor age affected muscle pH, sarcomere length, redness and yellowness, guanosine monophosphate, and hypoxanthine. The interaction between age and sex was significant (P < 0.05) for %dressing, %leg, L*, C14:1, C18:1n9 and C20:4n6. Shear force was lower in 16-week-old NC (P < 0.05). The 24-week-old NC had lower (P < 0.05) C13:0, C16:0, C18:0, C18:2n6t, C20:4n6, C22:6n-3, intramuscular fat and inosine 5'-monophosphate levels and higher (P < 0.05) C18:2n6c, C18:3n-3 and C20:3n-6 levels than the 16- and 20-week-old NC. Male NC had higher (P < 0.05) C13:0-, C14:0-, C18:2n6t-, C20:3n-6- and lower inosine levels than female NC. In conclusion, these data highlight age- and sex-specific differences in carcass and meat quality of NC and provide relevant information to support consumer-oriented decisions on the production, processing and nutritional value of NC.
Assuntos
Galinhas , Ácidos Graxos , Carne , Animais , Masculino , Feminino , Galinhas/crescimento & desenvolvimento , Galinhas/fisiologia , Carne/análise , Fatores Sexuais , Fatores Etários , Ácidos Graxos/análise , Tailândia , Ribonucleotídeos/análise , Músculo Esquelético/químicaRESUMO
BACKGROUND: Sleep-disordered breathing (SDB) and allergic rhinitis (AR) are common problems that can lead to worsening quality of life (QOL) in children with these conditions. There is scarce evidence on the QOL of children with SDB outside of the hospital setting with inconsistent evidence on the association of AR and QOL concerning the SDB in children. Thus, the primary objective of this study is to determine the QOL concerning the SDB of elementary school students by using OSA-18. We also aim to provide the relationship of allergic rhinitis to the QOL. METHODS: A cross-sectional study was conducted on all elementary school students, aged 6-12 years, from 10 elementary schools. The QOL of all participants was evaluated by the Thai version of the caregiver-administered OSA-18 questionnaire. The simple and multiple linear regression models were used to determine the effect of allergic rhinitis on the OSA-18 total scores. RESULTS: A total of 3,053 children were included in the final analysis, 50.1% male. At least a moderate impact on QOL from SDB was observed in 9.4% of the population. Children with AR had significantly higher mean total OSA- 18 scores than the children without AR (47.5 ± 15.0 VS 38.5 ± 13.1, p < 0.001). After the adjustment for age, gender, body mass index, household income, and history of asthma, the point estimate of the adjusted beta regression coefficient on the OSA-18 total score in children with AR was 7.82 (95% CI: 6.00-9.65, p < 0.001). Significant associations were observed between AR and all domains except for emotional distress. CONCLUSIONS: A substantial number of elementary school children had at least a moderate impact on the QOL from SDB, especially those with AR. Thus, effective screening of SDB in children with AR should be done to improve the QOL of these children.
Assuntos
Qualidade de Vida , Rinite Alérgica , Síndromes da Apneia do Sono , Estudantes , Humanos , Masculino , Feminino , Criança , Tailândia/epidemiologia , Rinite Alérgica/epidemiologia , Síndromes da Apneia do Sono/epidemiologia , Síndromes da Apneia do Sono/psicologia , Estudos Transversais , Inquéritos e Questionários , Estudantes/psicologia , Instituições AcadêmicasRESUMO
AIMS: This study aims to compare the trends in the quality of hospital care for WHO's three disease groups pre-, during, and post-COVID-19 pandemic peak in Thailand. METHODS: The study utilized existing hospital admission data from the Thai Health Information Portal (THIP) database, covering the period from 2017 to 2022. We categorized WHO's three disease groups: poverty-related, noncommunicable, and injury groups using the International Classification of Diseases (ICD)-10 of initial admission of patients, and we analyzed three major outcomes: prolonged (≥ 90th percentile) length of stay (LOS), hospital mortality, and readmission pre-, during, and post-COVID-19 pandemic peak. Relative weight (RW) of hospital reimbursements was used as a surrogate measure of the severity of the diseases. RESULTS: The average prolonged LOS of patients with poverty disease pre-, during, and post-COVID-19 pandemic peak were 7.1%, 10.8%, 9.05%, respectively. Respective hospital mortality rates were 5.02%, 6.22%, 6.05% and readmission were 6.98/1,000, 6.16/1,000, 5.43/1,000, respectively. For non-communicable diseases, the respective proportions in the prolonged LOS were 9.0%, 9.12%, and 7.58%, with respective hospital mortality being 10.65%, 8.86%, 6.62%, and readmissions were 17.79/1,000, 13.94/1,000, 13.19/1,000, respectively. The respective prolonged LOS for injuries were 8.75%, 8.55%, 8.25%. Meanwhile, respective hospital mortality were 4.95%, 4.05%, 3.20%, and readmissions were 1.99/1,000, 1.60/1,000, 1.48/1,000, respectively. The RW analysis reveals diverse impacts on resource utilization and costs. Most poverty-related and noncommunicable diseases indicate increased resource requirements and associated costs, except for HIV/AIDS and diabetes mellitus, showing mixed trends. In injuries, road traffic accidents consistently decrease resource needs and costs, but suicide cases show mixed trends. CONCLUSIONS: COVID-19 had a more serious impact, especially prolonged LOS and hospital mortality for poverty-related diseases more than noncommunicable diseases and injuries.
Assuntos
COVID-19 , Mortalidade Hospitalar , Tempo de Internação , Doenças não Transmissíveis , Readmissão do Paciente , Pobreza , Humanos , COVID-19/mortalidade , COVID-19/epidemiologia , COVID-19/economia , Tailândia/epidemiologia , Doenças não Transmissíveis/mortalidade , Doenças não Transmissíveis/epidemiologia , Doenças não Transmissíveis/economia , Readmissão do Paciente/estatística & dados numéricos , Mortalidade Hospitalar/tendências , Masculino , Feminino , Ferimentos e Lesões/mortalidade , Ferimentos e Lesões/economia , Ferimentos e Lesões/epidemiologia , Pessoa de Meia-Idade , Adulto , Idoso , SARS-CoV-2 , PandemiasRESUMO
BACKGROUND: Black flies are among the most medically and veterinary important insects, as adult females of certain species are the sole vector of Onchocerca volvulus. Here, a new black fly species belonging to the subgenus Asiosimulium Takaoka & Choochote, 2005, is described and formally named as Simulium (Asiosimulium) kittipati sp. nov. METHODS: Pupae and larvae of black flies were collected from available substrates in the stream from central Thailand. Pupae were individually separated in plastic tubes and maintained until adult flies emerged. The emerged adult flies associated with their pupal exuviae and cocoon as well as mature larvae preserved in 85% ethanol were used to describe the new species based on an integrated approach of morphological examination and molecular analysis of the COI gene. RESULTS: The new species is characterized in the female by the medium-long sensory vesicle with a medium-sized opening apically, scutum with three faint longitudinal vittae, and the ellipsoidal spermatheca; in the male by the number of upper-eye (large) facets in 20 vertical columns and 21 horizontal rows, hind basitarsus slender, nearly parallel-sided, and median sclerite much wider and upturned apically; in the pupa by the head and thoracic integument densely covered with tiny tubercles, and the pupal gill of arborescent type with 28-30 filaments; and in the larva by the postgenal cleft deep, nearly reaching the posterior margin of the hypostoma, and dark pigmented sheath of the subesophageal ganglion. The DNA barcode successfully differentiated the new species from its congeners with an interspecific genetic divergence of 1.74-18.72%, confirming the morphological identification that the species is a new member of the subgenus Asiosimulium. Phylogenetic analyses also indicated that the new species is genetically closely related to Simulium phurueaense Tangkawanit, Wongpakam & Pramual, 2018, further supporting its morphological classification. CONCLUSIONS: This is the ninth species assigned to the subgenus Asiosimulium within the genus Simulium Latreille, 1802. Taxonomic notes and identification keys are given to distinguish this new species from the eight known species members in its same subgenus. Additionally, a distribution map of all species members in this subgenus occurring in Thailand and other countries is provided.
Assuntos
Larva , Filogenia , Pupa , Simuliidae , Animais , Simuliidae/genética , Simuliidae/anatomia & histologia , Simuliidae/classificação , Tailândia , Feminino , Masculino , Pupa/anatomia & histologia , Pupa/genética , Pupa/classificação , Larva/anatomia & histologia , Larva/genética , Larva/classificação , Complexo IV da Cadeia de Transporte de Elétrons/genética , Insetos Vetores/anatomia & histologia , Insetos Vetores/genética , Insetos Vetores/classificaçãoRESUMO
BACKGROUND: Most real-world data on CGRP mAbs have been published from high-income countries such as the USA, Western countries, Japan, Korea, and Singapore. However, data from low- and middle-income countries in Southeast Asia is lacking. This is the first real-world study from Thailand to describe the efficacy of CGRP mAbs therapy in migraine patients and to analyze the response trends between episodic migraine and chronic migraine. METHODS: We conducted a single-center, real-world retrospective chart review study with an observation period of 6 months after CGRP mAbs initiation. We aim to compare treatment responses to CGRP mAbs between EM and CM patients. RESULTS: A total of 47 Thai patients were enrolled (median [IQR] age 37.2 [28.6-50.4] years; 85.1%F, 44.7% EM; 70.2% galcanezumab). There was no difference in baseline characteristics and migraine disability assessment (MIDAS) between EM and CM. The overall ≥ 30%, ≥ 50%, and ≥ 70% monthly migraine day reduction rates at 6 months were 89.0%, 71.6%, and 58.5% with higher responders in EM. There was a significant decrease in monthly headache days (MHDs) over time (adjusted ß = -0.42, p < 0.001) and a significant decrease in MIDAS score over time after the initiation of CGRP mAbs (adjusted ß = -1.12, p = 0.003). However, there were no differences between the two diagnoses. There was no significant decrease in the number of abortive medication pills used over time after the initiation of CGRP mAbs. CM had a significantly steeper trend compared to those with EM. CONCLUSION: The first real-world study in Thailand demonstrated that CGRP mAbs therapy had efficacy for migraine treatment, as evidenced by a reduction in MHDs, decreased disability, and reduced use of abortive medications. Additionally, the response pattern to CGRP mAbs therapy was similar between EM and CM in terms of MHDs reduction and MIDAS score improvement.
Assuntos
Transtornos de Enxaqueca , Humanos , Feminino , Masculino , Tailândia , Adulto , Pessoa de Meia-Idade , Transtornos de Enxaqueca/tratamento farmacológico , Estudos Retrospectivos , Anticorpos Monoclonais Humanizados/uso terapêutico , Anticorpos Monoclonais/uso terapêutico , Peptídeo Relacionado com Gene de Calcitonina/antagonistas & inibidores , Peptídeo Relacionado com Gene de Calcitonina/imunologia , Países em DesenvolvimentoRESUMO
BACKGROUND: Nutritional supplements for sports and exercise (NSSE) can facilitate the exogenous replenishment of the body. This study provides the first extensive overview of NSSE research through bibliometric and visual analyses. METHODS: We searched the Web of Science Core Collection database for literature related to "NSSE" from 1st January 2000 to 8th March 2024. A total of 1744 articles were included. CiteSpace, VOSviewer, and Bibliometrix R package software were used to analyze the data. RESULTS: Research in the NSSE can be divided into steady growth, exponential growth, fluctuating stage, and surge stages. The United States is the most active country in this field. In recent years, the leading countries have been Croatia, Colombia, Slovenia, Chile, Egypt, China, and Thailand. The Australian Institute of Sports is the top research institution in terms of number of publications. Burke, LM from Australia published the most articles. Research in this area has primarily been published in Nutrients in Switzerland. The study population mainly consisted of men, and postmenopausal women were the main focus of the female group. Coronary heart and cardiovascular diseases continue to dominate research. CONCLUSION: Research on the NSSE is developing rapidly, with an annual growth trend. Insulin resistance, sports nutrition, inflammation, alpha-linolenic acid, limb strength performance, female sex, and gut microbiota are the focus of the current research and trends for future research. Future research should focus on improving the scientific training system for athletes and quality of training and life for the general public.
Assuntos
Bibliometria , Suplementos Nutricionais , Exercício Físico , Esportes , Humanos , Esportes/estatística & dados numéricos , Masculino , Feminino , Saúde Global , Chile , Colômbia , Fenômenos Fisiológicos da Nutrição Esportiva , Croácia , TailândiaRESUMO
Objective: To investigate clusters of students' COVID-19 preventive behaviors and their associated factors. Methods: We surveyed undergraduate students using an online questionnaire at a regional university in southern Thailand, between April and June 2022. Statistical analyses included latent class analysis and multinomial regression analysis. Results: Three latent classes were identified: moderately consistent practitioner (7.5%), high compliance overall (48.9%), and good compliance with routine safeguards (43.6%). Females tended to have high compliance overall (RRR 2.46 95% CI 1.23-4.94), and higher academic performance was associated with high compliance overall and good routine safeguards. Perceived threats from COVID-19 were associated with good compliance with routine safeguards (RRR 4.21 95% CI 1.70-10.45). Benefits of actions and clear cues to action were associated with high overall compliance (RRR 5.24 95% CI 2.13-12.90). Students who perceived feasibility were more likely to be moderately consistent practitioners. Conclusion: The common clusters of the students' preventive behaviors were high compliance overall and good compliance with routine preventions. Female, academic performance, perceived threats, and perceived benefits and cues to action were associated with compliance.
Assuntos
COVID-19 , Estudantes , Humanos , Tailândia , Feminino , Masculino , COVID-19/prevenção & controle , Estudantes/psicologia , Universidades , Adulto Jovem , Inquéritos e Questionários , SARS-CoV-2 , Adulto , Adolescente , Comportamentos Relacionados com a Saúde , Fidelidade a Diretrizes/estatística & dados numéricosRESUMO
Background: Coronavirus 2019 (COVID-19) causes lung tissue inflammation, affects mental health, and disturbs sleep and the musculoskeletal system. This study aimed to investigate the effects of COVID-19 on physical function and quality of life by comparing the body composition, physical fitness, sleep quality and quality of life between Thai young adults with and without post COVID-19 infection. Methods: A cross-sectional study was comprised of two matched groups (post COVID-19 group and non COVID-19 group) with 36 participants in each group. Data about body composition, physical fitness, sleep quality and quality of life were collected using the bioelectrical impedance analysis, the 1-min sit-to-stand test, the hand grip strength test, the Pittsburgh sleep quality questionnaire and the EuroQol-5D-5L, respectively. Independent samples T-test, Mann-Whitney U test and Chi-square test were used to compare between the two groups. Results: The changes in oxygen saturation and respiratory rate after the physical fitness test and the sleep quality analysis showed a statistically significant difference between the groups with and without post COVID-19 infection (p = 0.006, p = 0.003 and p = 0.003, respectively). However, quality of life and body composition were not significantly different between groups. Conclusions: COVID-19 influenced the changes in oxygen saturation and respiratory rate after the physical fitness test and the sleep quality analysis in young adults. The results should be utilized to facilitate physical rehabilitation for COVID-19-infected individuals following infection. Those who have not been infected with COVID-19 must be informed of self-protection measures to avoid contracting the virus.
Assuntos
Composição Corporal , COVID-19 , Aptidão Física , Qualidade de Vida , Qualidade do Sono , Humanos , COVID-19/psicologia , Estudos Transversais , Masculino , Feminino , Adulto Jovem , Aptidão Física/fisiologia , Adulto , SARS-CoV-2 , Tailândia , Inquéritos e QuestionáriosRESUMO
A novel bacterium, designated as strain LOR1-02T and isolated from a lichen sample collected from Kham Riang Subdistrict, Kantharawichai District, Maha Sarakham Province, Thailand, underwent thorough investigation utilizing a polyphasic taxonomic approach. Strain LOR1-02T demonstrated growth within a temperature range of 20-42 °C (optimal at 30 °C), pH range of 5.0-7.5 (optimal at pH 7.0), and tolerance to 4.0% (w/v) NaCl. Phylogenetic analysis revealed its close relation to Paracraurococcus ruber JCM 9931T, with a 16S rRNA gene sequence similarity of 97.16%, placing it within the genus Paracraurococcus. The approximate genome size of strain LOR1-02T was determined to be 8.6 Mb, with a G + C content of 70.9 mol%. Additionally, ANIb, ANIm, and AAI values between the whole genomes of strain LOR1-02T and type strains were calculated as 82.6-83.4%, 86.1-86.8%, and 81.4-82.2%, respectively, while the dDDH value was determined to be 26.3-28.5% (C.I. 24.0-31.0%). The predominant fatty acids detected were C18:1ω7c and/or C18:1ω6c, C16:0, and C18:12OH. The major ubiquinone identified was Q-10, and the polar lipids included phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine, diphosphatidylglycerol, along with unidentified phosphoaminolipid, lipids, and an amino lipid. Based on comprehensive phenotypic, chemotaxonomic, and genotypic characterization, it is concluded that strain LOR1-02T represents a novel species within the genus Paracraurococcus, for which the name Paracraurococcus lichenis sp. nov. is proposed. The type strain designation is LOR1-02T (= JCM 33121T = NBRC 112776T = TISTR 2503T).
Assuntos
Técnicas de Tipagem Bacteriana , Composição de Bases , DNA Bacteriano , Ácidos Graxos , Líquens , Filogenia , RNA Ribossômico 16S , RNA Ribossômico 16S/genética , Tailândia , Ácidos Graxos/análise , Ácidos Graxos/química , Líquens/microbiologia , DNA Bacteriano/genética , Análise de Sequência de DNA , Genoma Bacteriano , Ubiquinona/química , Ubiquinona/análise , Fosfolipídeos/análiseRESUMO
OBJECTIVES: The study aimed to evaluate the clinical crown length (CCL) among patients diagnosed with altered passive eruption (APE), the causes of a gummy smile, the prevalence of APE, and the correlation between parameters. MATERIALS AND METHODS: A total of 86 gummy smile patients (516 teeth) underwent clinical examination and assessment using cone-beam computed tomography (CBCT), photography, and intraoral scanning. RESULTS: Significantly shorter CCL and distance between the cementoenamel junction and bone crest (CEJ-BC) were observed among APE-affected teeth (p < 0.05). Among the patients, 56.1% of patients were diagnosed with APE, and most of them were affected by a combination of APE and hypermobile upper lip (HUL). Based on 183 APE-affected teeth, the prevalence of APE types and subtypes was as follows: APE1A (96; 19.3%), APE1B (78; 15.9%), APE2A (8; 1.6%), and APE2B (1; 0.2%). Positive correlations were found between keratinized gingival width (KGW) and bone thickness (BT), while negative correlations were observed between gingival thickness (GT) and BT. CONCLUSION: Shorter CCL and CEJ-BC were the highlighted features of APE. APE affected approximately half of the gummy smile patients, with most of them presenting with a combination of HUL. Almost teeth affected by APE were classified as Type I, with a nearly equal distribution between subtypes A and B. CLINICAL RELEVANCE: The clinical and radiographic features of APE contribute to a better understanding of this condition and facilitate the management of patients affected by APE. Approximately half of gummy smile patients will require multidisciplinary treatment.