RESUMO
Waste collectors collect, transport, and process the garbage produced by people living in the city. Nowadays, this activity requires special attention due to the environmental impact of garbage and its potential consequences on human health. The aim of this study was to evaluate potential cytotoxic and mutagenic effects of garbage collection on waste collectors. For this purpose, a total of 47 male waste collectors aged from 24 to 53 years were included in the experimental group. A total of 30 men matched by age were used as the control group. Cytotoxicity and mutagenicity were analyzed by micronucleus test in buccal mucosaI cells. No statistically significant difference (p>0.05) in the frequency of micronuclei was detected in the waste collectors when compared to controls. Nevertheless, higher frequencies of karyolysis and pyknosis (p<0.05) were detected in buccal mucosaI cells from waste collectors when compared to matched controls. Taken together, our results indicate that waste collectors comprise an at-risk group as a result of increased cytotoxicity apparent from buccal mucosa cells.
Assuntos
Análise Citogenética/métodos , Monitoramento Ambiental/métodos , Mucosa Bucal/metabolismo , Saúde Ocupacional/estatística & dados numéricos , Resíduos Sólidos/análise , Adulto , Núcleo Celular/efeitos dos fármacos , Núcleo Celular/genética , Sobrevivência Celular/efeitos dos fármacos , Substâncias Perigosas/análise , Substâncias Perigosas/farmacologia , Humanos , Masculino , Micronúcleos com Defeito Cromossômico/efeitos dos fármacos , Testes para Micronúcleos/métodos , Pessoa de Meia-Idade , Mucosa Bucal/citologia , Exposição Ocupacional/análise , Saúde Ocupacional/normas , Adulto JovemRESUMO
O Programa Nacional de Capacitaçäo Técnico-Científica compreende 220 fichas toxicológicas contendo identificaçäo da substância; sua utilizaçäo; propriedades físicas e químicas; recipientes de estocagem; métodos de detecçäo e de determinaçäo no ar; riscos físicos e orgânicos; patologia; toxicologia; recomendaçöes; manipulaçäo; ponto de vista médico e bibliografias