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3.
Ginecol Obstet Mex ; 82(5): 314-24, 2014 May.
Artigo em Espanhol | MEDLINE | ID: mdl-24937947

RESUMO

BACKGROUND: To decrease maternal and fetal morbidity oftem is indicated the elective termination of pregnancy; when the cervix is unfavourable, it is possible to try to artificially reproduce these changes with exogenous prostaglandins. OBJECTIVES: Comparative evaluation of maternal and fetal results between patients in which cervical ripening is practiced with indication of premature rupture of membranes and those with prolonged pregnancy. MATERIAL AND METHOD: Historic cohorts study about pregnancies requiring cervical ripening, either for premature rupture of membranes or for gestational age > or = 41 weeks, in the "Miguel Servet" Hospital (Zaragoza, Spain), from 15/11/2005 to 15/05/2008. In all the cases dinoprostone (slow release vaginal system) was employed and the initial Bishop score was < 7. The main analysed outcomes were: intrapartum fetal heart monitoring characteristics, type of delivery, umbilical artery pH, Apgar score, hospitalization in neonatal unit requirement and time from cervical ripening start to delivery. RESULTS: Neonatal hospitalization was significantly more frequent in the ruptured membranes cohort (11.70% vs 2.33%); p = 0.001. This difference could be justified by gestational age (OR: 2,623. IC: 0.515-13.353. P = 0.246). It was observed more time cervical ripening - delivery in prolonged pregnancies cohort (25.96h vs 20.11h); p < 0.001. Umbilical cord medium pH was significantly superior in ruptured membranes group (7.25 vs 7.23); p = 0.017. No significant differences were observed in the rest of analyzed outcomes. CONCLUSIONS: Pregnancies electively ended for premature rupture of membranes are associated with a shorter time to delivery and a slightly superior umbilical cord pH than induced prolonged pregnancies. Neonatal hospitalization requirement is determined by gestational age but not by the rupture of the membranes. Cervical ripening in those patients has been demonstrated to be secure and effective.


Assuntos
Ruptura Prematura de Membranas Fetais/cirurgia , Trabalho de Parto Induzido , Gravidez Prolongada/cirurgia , Adulto , Protocolos Clínicos , Estudos de Coortes , Feminino , Humanos , Gravidez , Resultado da Gravidez
4.
Femina ; 36(7): 419-423, jul. 2008.
Artigo em Português | LILACS | ID: lil-508219

RESUMO

A ruptura prematura das membranas (RPM) é uma das principais complicações do período gestacional, sendo responsável por elevada taxa de morbimortalidade perinatal, principalmente quando ocorre em gestações precoces, no segundo trimestre e quando é acompanhada por oligoidrâmnio acentuado. Até o presente momento, não existe tratamento capaz de selar as membranas amnióticas. O manejo de casos de ruptura prematura das membranas espontânea no segundo trimestre muitas vezes consiste em indução do parto por causa do risco de infecção materna e baixa probabilidade de sobrevivência neonatal. A forma iatrogênica, apesar de ser menos freqüente, também é um problema, uma vez que procedimentos de amniocentese e fetoscopia estão sendo realizados com maior freqüência. Desta forma, são vários os esforços na tentativa de encontrar um tratamento para RPM, que diminua de forma significativa a alta incidência de mortalidade neonatal. O objetivo deste artigo é fazer uma revisão das técnicas experimentais que já foram utilizadas para o tratamento da ruptura prematura das membranas em gestações precoces.


The premature rupture of the membranes in the main complication of the pregnant period, being responsible for a high incidence of perinatal morbimortality, mainly when it happens in early pregnancy at the second trimester and it is associated with serious oligohydramnios. Until the present moment, there is no treatment to close the amniotic membranes. The treatment of the spontaneous premature rupture of the membranes in the second trimester pregnancy consist in, many time, induction of the labour because of the risk of maternal infection and the low probability of neonatal survival. The iatrogenic one, although less usual, it is a problem because procedures like amniocentesis and fetoscopy are developing with more frequency. So, efforts trying to find a way to treat the cause of the premature rupture of membranes to treat the cause of the premaure of membranes are being done in order to decrease the high incidence of the neonatal mortality. The objective of this article is to do a review of experimental techniques that had been already used for the treatment of the premature of the membranes in early pregnancy.


Assuntos
Feminino , Gravidez , Adesivo Tecidual de Fibrina/uso terapêutico , Corticosteroides/uso terapêutico , Oligo-Hidrâmnio/cirurgia , Segundo Trimestre da Gravidez , Ruptura Prematura de Membranas Fetais/cirurgia , Ruptura Prematura de Membranas Fetais/prevenção & controle , Ruptura Prematura de Membranas Fetais/terapia , Mortalidade Perinatal , Complicações na Gravidez
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