RESUMO

Cystic endometrial hyperplasia (CEH)-pyometra syndrome is the most common uterine pathological condition reported in breeding bitches, however, their described effects on fertility are limited to uterine disorders and conception rates. As the preantral follicle population represents the available reserve of gametes recruited during the lifespan, the aim of this study was to evaluate the effects of CEH-pyometra syndrome on the: (i) preantral follicle morphology, (ii) developing follicle rates, and (iii) preantral follicle and stromal cell densities. Ovarian fragments from bitches subjected to elective or therapeutic ovariohysterectomy were allocated according to uterine diagnosis as follows: control (n = 7, clinically healthy), CEH-mucometra (n = 8, uterine lumen filled with a sterile mucus), and pyometra (n = 17, presence of a purulent mucus) groups. Overall, the control group had 3.4 and 4.1-fold higher probability (P < 0.0001) of the presence of normal preantral follicles compared with CEH-mucometra and pyometra groups, respectively. Moreover, ovarian fragments from the pyometra group showed an increase in the percentage of developing follicles (P < 0.05) compared to the control. Both CEH-mucometra and pyometra groups showed lower (P < 0.05) preantral follicle and stromal cell densities (P < 0.05) compared to the control. In summary, the CEH-pyometra syndrome decreased the percentage of morphologically normal follicles and enhanced the developing follicle rates. Additionally, a reduction of preantral follicle and stromal cell densities suggests that the inappropriate uterine environment induced by CEH-pyometra syndrome can lead to premature depletion of ovarian reserve.

Assuntos

RESUMO

Piometra é uma doença que afeta o útero de fêmeas causando infecção e inflamação com acúmulo de grande quantidade de exsudato purulento ou mucopurulento. Ocorre em todas as espécies domésticas, sendo mais comum em cadelas e vacas. Sua importância em cada espécie está relacionada ao número de casos e sua severidade, dentro de suas particularidades. O objetivo com esta revisão foi reunir estudos referentes à piometra em fêmeas domésticas, incluindo a epidemiologia, sinais clínicos, diagnóstico e tratamento nas principais espécies acometidas.

Pyometra is a disease that affects the uterus of females causing infection and inflammation with an accumulation of large amounts of purulent or mucopurulent exudate. It occurs in all domestic species, being more common in bitches and cows. Its importance in each species is related to the number of cases and its severity, within its particularities. The objective of this review was to gather studies referring to pyometra in domestic females, including epidemiology, clinical signs, diagnosis, and treatment in the main species affected.

La piometra es una enfermedad que afecta el útero de las hembras causando infección e inflamación com acumulación de grandes cantidades de exudado purulento o mucopurulento. Ocurre en todas las espécies domésticas, siendo más frecuente en perras y vacas. Su importancia en cada especie está relacionada con el número de casos y su severidad, dentro de sus particularidades. El objetivo de esta revisión fue reunir estudios sobre piometra en hembras domésticas, incluyendo epidemiología, signos clínicos, diagnóstico y tratamiento en las principales especies afectadas.

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RESUMO

The pathologies that affect the reproductive systems are occurring more frequently in veterinarymedicine, because diseases are multifactorial, so may be regional variations in the incidence of certainreproductive abnormalities. This work was conducted a survey of breeding occurrences in domestic cats, theyparticipated in the Department of Animal husbandry (SRA) of the Veterinary Hospital, located at UniversidadeFederal Rural da Amazônia (UFRA). In the period of 1 March 2013 to 2015, 18 December was 472 catsparticipated in the metropolitan area of Bethlehem, they being 432 females and 40 males, which was related tothe factors of race, gender, and age. Most of the animals were stray animals and adult age group, mostlyfemales affected in different reproductive organs, with disease in the uterus and ovaries and occurrence as rarecases of cystic Dysplasia, puerperal metritis, stump pyometra, ovarian cancer and endometrial polyps. Inaddition, there was interest in animals to seek prenatal diagnosis of pregnancy of animals.

Assuntos

RESUMO

The pathologies that affect the reproductive systems are occurring more frequently in veterinarymedicine, because diseases are multifactorial, so may be regional variations in the incidence of certainreproductive abnormalities. This work was conducted a survey of breeding occurrences in domestic cats, theyparticipated in the Department of Animal husbandry (SRA) of the Veterinary Hospital, located at UniversidadeFederal Rural da Amazônia (UFRA). In the period of 1 March 2013 to 2015, 18 December was 472 catsparticipated in the metropolitan area of Bethlehem, they being 432 females and 40 males, which was related tothe factors of race, gender, and age. Most of the animals were stray animals and adult age group, mostlyfemales affected in different reproductive organs, with disease in the uterus and ovaries and occurrence as rarecases of cystic Dysplasia, puerperal metritis, stump pyometra, ovarian cancer and endometrial polyps. Inaddition, there was interest in animals to seek prenatal diagnosis of pregnancy of animals.(AU)

Assuntos

RESUMO

The endothelial pyometra is a disease that affects more frequently reproductively active adult females. Characterized by inflammation and accumulation of exudate in the uterine cavity, generally associated with bacterial infections. The present study aimed to evaluate the resistance profile of Escherichia coli isolates from 42 female dogs diagnosed with pyometra, seen at the Department of Small Animal Surgery, Hospital of Veterinary Medicine, Federal University of Bahia. To perform the bacteriological analysis, a sample of the contents of the uterus was obtained immediately after surgery of ovariosalpingohisterectomy therapy (OSH) and sent to the laboratory. Microbiological analysis showed a predominance of the bacterium Escherichia coli in 40.5% (15/37). Strains of Escherichia coli isolates showed higher rates of resistance to antimicrobial erythromycin (93.3 %), azithromycin (80 %), ampicillin, amoxicillin, and cephalothin (40% each). This study reinforces the need to perform the microbiological examination for epidemiological purposes and the correct therapeutic application, thereby avoiding the indiscriminate use of antimicrobials and the potential emergence of multidrug-resistant  strains.

A piometra é uma enfermidade endotelial que acomete com mais frequência as fêmeas adultas         e ativas reprodutivamente. Caracteriza-se por inflamação e acúmulo de exsudato na  cavidade uterina que geralmente está associada a infecções bacterianas. O presente estudo objetivou avaliar   o perfil de resistência de isolados de Escherichia coli a partir do conteúdo uterino de 42 fêmeas caninas, atendidas no Setor de Cirurgia de Pequenos Animais do Hospital de Medicina Veterinária da Universidade Federal da Bahia, com diagnóstico de piometra. Para a realização da análise bacteriológica, uma amostra do conteúdo uterino foi obtida imediatamente após o ato cirúrgico de ovariosalpingohisterectomia terapêutica (OSH) e encaminhada  para  o  laboratório.  Após  análise microbiológica observou-se uma predominância da bactéria Escherichia coli em 40,5% (15/37). As cepas de Escherichia coli isoladas apresentaram os maiores índices de resistência aos antimicrobianos eritromicina (93,3%), azitromicina (80%), ampicilina, amoxacilina e cefalotina (40% cada). Tal estudo reforça a necessidade da realização do exame microbiológico com finalidade epidemiológica e correta aplicação terapêutica, evitando, com isso, a utilização indiscriminada de antimicrobianos e potencial surgimento de estirpes   multirresistentes.

Assuntos

RESUMO

The endothelial pyometra is a disease that affects more frequently reproductively active adult females. Characterized by inflammation and accumulation of exudate in the uterine cavity, generally associated with bacterial infections. The present study aimed to evaluate the resistance profile of Escherichia coli isolates from 42 female dogs diagnosed with pyometra, seen at the Department of Small Animal Surgery, Hospital of Veterinary Medicine, Federal University of Bahia. To perform the bacteriological analysis, a sample of the contents of the uterus was obtained immediately after surgery of ovariosalpingohisterectomy therapy (OSH) and sent to the laboratory. Microbiological analysis showed a predominance of the bacterium Escherichia coli in 40.5% (15/37). Strains of Escherichia coli isolates showed higher rates of resistance to antimicrobial erythromycin (93.3 %), azithromycin (80 %), ampicillin, amoxicillin, and cephalothin (40% each). This study reinforces the need to perform the microbiological examination for epidemiological purposes and the correct therapeutic application, thereby avoiding the indiscriminate use of antimicrobials and the potential emergence of multidrug-resistant  strains. (AU)

A piometra é uma enfermidade endotelial que acomete com mais frequência as fêmeas adultas         e ativas reprodutivamente. Caracteriza-se por inflamação e acúmulo de exsudato na  cavidade uterina que geralmente está associada a infecções bacterianas. O presente estudo objetivou avaliar   o perfil de resistência de isolados de Escherichia coli a partir do conteúdo uterino de 42 fêmeas caninas, atendidas no Setor de Cirurgia de Pequenos Animais do Hospital de Medicina Veterinária da Universidade Federal da Bahia, com diagnóstico de piometra. Para a realização da análise bacteriológica, uma amostra do conteúdo uterino foi obtida imediatamente após o ato cirúrgico de ovariosalpingohisterectomia terapêutica (OSH) e encaminhada  para  o  laboratório.  Após  análise microbiológica observou-se uma predominância da bactéria Escherichia coli em 40,5% (15/37). As cepas de Escherichia coli isoladas apresentaram os maiores índices de resistência aos antimicrobianos eritromicina (93,3%), azitromicina (80%), ampicilina, amoxacilina e cefalotina (40% cada). Tal estudo reforça a necessidade da realização do exame microbiológico com finalidade epidemiológica e correta aplicação terapêutica, evitando, com isso, a utilização indiscriminada de antimicrobianos e potencial surgimento de estirpes   multirresistentes. (AU)

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RESUMO

O presente trabalho teve por objetivo descrever dois casos de piometra associado a leiomioma uterino. Foram atendidos no Hospital Veterinário das Faculdades Integradas de Ourinhos, dois casos de piometra associada ao leiomioma uterino. O primeiro foi de uma cadela sem raça definida (SRD), com sete anos de idade, pesando 8,5 Kg, com histórico de aumento de volume na região abdominal e o segundo caso foi uma cadela da raça Poodle, com 15 anos de idade, pesando 5,6 Kg, com histórico de tosse, inapetência, apatia, polidipsia e vômito há dois dias. Após a confirmação do diagnóstico, optou-se pelo tratamento cirúrgico para reversão do quadro em ambas as cadelas. No pós-operatório, foi prescrito enrofloxacina 5 mg/Kg, SID, por dez dias e meloxicam 0,1 mg/Kg, SID, por três dias, além do curativo tópico com iodo povidine. No retorno, ambas as cadelas apresentaram completa melhora clínica.

This study aimed to describe two cases of pyometra associated with uterine leiomyoma. Were seen at the Veterinary Hospital of Integrated Schools of the Ourinhos, two cases of pyometra associated with uterine leiomyoma. The first was a mixed breed bitch with seven years of age, weighing 8.5kg, with a history of swelling in the abdominal region and the second case was a Poodle breed bitch, with 15 years of age, weighing 5.6 kg, with a history of cough, anorexia, lethargy, polydipsia and vomiting for two days. After confirming the diagnosis, we opted for surgical treatment to reverse the state in both dogs. In the post-surgical, was prescribed enrofloxacin 5mg/Kg, once a day, for ten days and meloxicam 0.1mg/Kg, once a day for three days and topical povidone iodine. In return, both dogs had complete clinical improvement.

Assuntos

RESUMO

O presente trabalho teve por objetivo descrever dois casos de piometra associado a leiomioma uterino. Foram atendidos no Hospital Veterinário das Faculdades Integradas de Ourinhos, dois casos de piometra associada ao leiomioma uterino. O primeiro foi de uma cadela sem raça definida (SRD), com sete anos de idade, pesando 8,5 Kg, com histórico de aumento de volume na região abdominal e o segundo caso foi uma cadela da raça Poodle, com 15 anos de idade, pesando 5,6 Kg, com histórico de tosse, inapetência, apatia, polidipsia e vômito há dois dias. Após a confirmação do diagnóstico, optou-se pelo tratamento cirúrgico para reversão do quadro em ambas as cadelas. No pós-operatório, foi prescrito enrofloxacina 5 mg/Kg, SID, por dez dias e meloxicam 0,1 mg/Kg, SID, por três dias, além do curativo tópico com iodo povidine. No retorno, ambas as cadelas apresentaram completa melhora clínica.(AU)

This study aimed to describe two cases of pyometra associated with uterine leiomyoma. Were seen at the Veterinary Hospital of Integrated Schools of the Ourinhos, two cases of pyometra associated with uterine leiomyoma. The first was a mixed breed bitch with seven years of age, weighing 8.5kg, with a history of swelling in the abdominal region and the second case was a Poodle breed bitch, with 15 years of age, weighing 5.6 kg, with a history of cough, anorexia, lethargy, polydipsia and vomiting for two days. After confirming the diagnosis, we opted for surgical treatment to reverse the state in both dogs. In the post-surgical, was prescribed enrofloxacin 5mg/Kg, once a day, for ten days and meloxicam 0.1mg/Kg, once a day for three days and topical povidone iodine. In return, both dogs had complete clinical improvement.(AU)

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RESUMO

A case report patient with pyometra is infrequent. The aim of this communication is to present rare manifestations of it. A 65-year-old female with an ovarian cyst diagnosis was evaluated. She reported that since two years ago abdominal perimeter increased progressively. Physical exam revealed a 28 cm abdominal tumor. An ultrasound and a CT scan supported clinical diagnosis. LABORATORY TEST RESULTS: white cell count 7100/mm3, and CA-125: 214 U/mL. With a presumptive ovarian cancer diagnosis an exploratory laparotomy was carried out. OPERATIVE FINDINGS: a 26 cm uterus with atrophic ovaries. A total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. The histopathology test results revealed a massive coagulated pyometra. CONCLUSION: A giant pyometra is an exceptional event, and also it can increase CA-125 serum levels.

Assuntos