RESUMO
The quantification of angiogenesis and metalloproteinases may be useful in cholesteatoma behavior assessment as markers of its aggressiveness. The objective of this study is to compare markers CD31, MMP2 and MMP9 in pediatric and adult patients. This study is based on cross-sectional studies of pediatric (
Assuntos
Colesteatoma da Orelha Média/diagnóstico , Adolescente , Adulto , Fatores Etários , Criança , Colesteatoma da Orelha Média/patologia , Colesteatoma da Orelha Média/cirurgia , Tecido Conjuntivo/patologia , Estudos Transversais , Orelha Média/irrigação sanguínea , Orelha Média/patologia , Orelha Média/cirurgia , Epitélio/patologia , Matriz Extracelular/patologia , Feminino , Humanos , Masculino , Metaloproteinase 2 da Matriz/análise , Metaloproteinase 9 da Matriz/análise , Pessoa de Meia-Idade , Neovascularização Patológica/diagnóstico , Neovascularização Patológica/patologia , Otite Média/diagnóstico , Otite Média/patologia , Molécula-1 de Adesão Celular Endotelial a Plaquetas/análise , Prognóstico , Adulto JovemRESUMO
Most investigators consider the caroticotympanic artery to be a normal branch of the petrous portion of the internal carotid artery, although some authors disagree. The present study was conducted on forty human temporal bones removed from adult cadavers of both sexes. Twenty pieces were injected and dissected under a surgical microscope, 10 pieces were injected and submitted to corrosion, and 10 were injected and diaphanized in order to observe the frequency of the caroticotympanic artery in the petrous portion of the internal carotid artery. The caroticotympanic artery was not observed in any of the pieces submitted to microdissection and was observed in only 1 of the pieces (10%) submitted to corrosion and also in 1 of the diaphanized pieces (10%). In both cases, only one artery was present. Based on the present results showing that the rate of occurrence of the caroticotympanic artery was very low by the three techniques utilized (microdissection 0%; corrosion 10%; diaphanization 10%), it is possible to conclude that, anatomically, the artery should be considered as a variation and not as a normal branch of the petrous portion of the internal carotid artery, in agreement with most literature reports.
Assuntos
Artéria Carótida Interna/anatomia & histologia , Orelha Média/anatomia & histologia , Orelha Média/irrigação sanguínea , Osso Petroso/anatomia & histologia , Osso Petroso/irrigação sanguínea , Artéria Carótida Interna/anormalidades , Feminino , Humanos , MasculinoRESUMO
A case of permanent pulsatile tinnitus of the left ear in a patient with hypertriglyceridemia is reported. The combined radiological study with computed tomography, magnetic resonance imaging, and digital angiography excluded a glomus tumor and revealed an enlarged, high-position jugular bulb with slow blood flow. Causes of pulsatile tinnitus are discussed. We conclude that imaging techniques play a major role in the diagnosis of head and neck vascular abnormalities.