RESUMO
Congenital cutaneous pyogenic granuloma is a rare benign vascular tumor with clinical and histopathological features similar to infantile hemangioma. It usually presents as a red, pedunculated and highly friable papule. On histopathological analysis, one can see a capillary vessel proliferation with lobular pattern and endothelial proliferation. The differential diagnosis is based on negativity of glucose transporter 1 (GLUT1) immunochemistry studies. We report two infants with congenital pyogenic granuloma, one with a unique cutaneous lesion and the other with multiple lesions affecting both skin and mucosal surfaces. These two cases highlight the importance of the differential diagnosis based on the GLUT1 immunochemistry analysis considering the distinct treatments required to these infant vascular tumors.
Assuntos
Transportador de Glucose Tipo 1/metabolismo , Granuloma Piogênico , Proteínas de Neoplasias/metabolismo , Neoplasias Vasculares , Diagnóstico Diferencial , Feminino , Granuloma Piogênico/congênito , Granuloma Piogênico/diagnóstico , Granuloma Piogênico/metabolismo , Granuloma Piogênico/patologia , Humanos , Lactente , Recém-Nascido , Masculino , Neoplasias Vasculares/congênito , Neoplasias Vasculares/diagnóstico , Neoplasias Vasculares/metabolismo , Neoplasias Vasculares/patologiaRESUMO
Abstract: Rapidly involuting congenital hemangioma is a rare vascular tumor that generally has a good prognosis. The authors describe a case of a newborn girl with a left cervical vascular lesion. Image exams were performed, and the lesion slowly decreased, leaving redundant skin. Considering all of the findings, a final diagnosis of a rapidly involuting congenital hemangiomas was suspected.
Assuntos
Humanos , Feminino , Recém-Nascido , Neoplasias Vasculares/congênito , Neoplasias Vasculares/patologia , Hemangioma/congênito , Hemangioma/patologia , Remissão Espontânea , Pele/patologia , Fatores de Tempo , Imageamento por Ressonância Magnética , Ultrassonografia , Neoplasias Vasculares/diagnóstico por imagem , Hemangioma/diagnóstico por imagemRESUMO
Rapidly involuting congenital hemangioma is a rare vascular tumor that generally has a good prognosis. The authors describe a case of a newborn girl with a left cervical vascular lesion. Image exams were performed, and the lesion slowly decreased, leaving redundant skin. Considering all of the findings, a final diagnosis of a rapidly involuting congenital hemangiomas was suspected.