RESUMO
Se describen diversos aspectos de la mononucleosis infecciosa: transmisión, etiología, anatomopatología,manifestaciones clínicas, diagnóstico, pronóstico, tratamiento y complicaciones posibles de esta enfermedad y se menciona la patogenicidad del Virus Epstein-Barr
Assuntos
Humanos , Herpesvirus Humano 4/patogenicidade , Mononucleose Infecciosa/transmissão , Mononucleose Infecciosa/etiologia , Mononucleose Infecciosa/fisiopatologia , Mononucleose Infecciosa/diagnóstico , Mononucleose Infecciosa/terapia , Sinais e Sintomas , Diagnóstico Diferencial , PrognósticoRESUMO
Se describen diversos aspectos de la mononucleosis infecciosa: transmisión, etiología, anatomopatología,manifestaciones clínicas, diagnóstico, pronóstico, tratamiento y complicaciones posibles de esta enfermedad y se menciona la patogenicidad del Virus Epstein-Barr
Assuntos
Humanos , Diagnóstico Diferencial , Herpesvirus Humano 4/patogenicidade , Mononucleose Infecciosa/diagnóstico , Mononucleose Infecciosa/etiologia , Mononucleose Infecciosa/fisiopatologia , Mononucleose Infecciosa/terapia , Mononucleose Infecciosa/transmissão , Prognóstico , Sinais e SintomasAssuntos
Herpesvirus Humano 4/isolamento & purificação , Mononucleose Infecciosa/diagnóstico , Linfonodos/microbiologia , Biópsia , Feminino , Humanos , Recém-Nascido , Mononucleose Infecciosa/microbiologia , Mononucleose Infecciosa/transmissão , Masculino , Gravidez , Complicações Infecciosas na Gravidez/imunologiaRESUMO
Intrafamilial transmission of Epstein-Barr virus infections was studied in 35 familial. After infectious mononucleosis was diagnosed in an index child, all siblings were tested for antibodies to EBV. Susceptible children were retested in four to eight weeks. In five families, a concurrent seroconversion was detected in an asymptomatic younger child. Two of 35 seronegative siblings developed clinical IM, confirmed serologically, during the study period. Overall, there evidence of spread in 7 (20%) of the 35 families. We conclude that there is significant intrafamilial transmission of IM. Our findings are compatible with an incubation period of four to six weeks.