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1.
An. bras. dermatol ; An. bras. dermatol;95(3): 372-375, May-June 2020. graf
Artigo em Inglês | LILACS, Coleciona SUS | ID: biblio-1130880

RESUMO

Abstract Pseudomycetoma is an extremely rare deep mycosis, caused by dermatophytic fungi that penetrate the tissue from infected follicles of tinea capitis. Both clinically and histopathology are similar to eumycetoma, being distinguished through the isolation of the fungus, which in the case of pseudomycetoma can be Microsporum spp. or Trichophyton spp. genre. We present a 24-year-old man with an exuberant tumor in the occipital region with fistula, whose histopathological examination evidenced grains composed of hyaline hyphae and the culture for fungi isolated the agent Microsporum canis. Combined treatment of surgical excision followed by oral griseofulvin for two years was performed, with resolution of the condition.


Assuntos
Humanos , Masculino , Adulto Jovem , Dermatoses do Couro Cabeludo/microbiologia , Dermatomicoses/microbiologia , Micetoma/microbiologia , Microsporum/isolamento & purificação , Dermatoses do Couro Cabeludo/cirurgia , Dermatoses do Couro Cabeludo/patologia , Resultado do Tratamento , Dermatomicoses/cirurgia , Dermatomicoses/patologia , Imunocompetência , Micetoma/cirurgia , Micetoma/patologia
2.
An Bras Dermatol ; 95(3): 372-375, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32278631

RESUMO

Pseudomycetoma is an extremely rare deep mycosis, caused by dermatophytic fungi that penetrate the tissue from infected follicles of tinea capitis. Both clinically and histopathology are similar to eumycetoma, being distinguished through the isolation of the fungus, which in the case of pseudomycetoma can be Microsporum spp. or Trichophyton spp. genre. We present a 24-year-old man with an exuberant tumor in the occipital region with fistula, whose histopathological examination evidenced grains composed of hyaline hyphae and the culture for fungi isolated the agent Microsporum canis. Combined treatment of surgical excision followed by oral griseofulvin for two years was performed, with resolution of the condition.


Assuntos
Dermatomicoses/microbiologia , Microsporum/isolamento & purificação , Micetoma/microbiologia , Dermatoses do Couro Cabeludo/microbiologia , Dermatomicoses/patologia , Dermatomicoses/cirurgia , Humanos , Imunocompetência , Masculino , Micetoma/patologia , Micetoma/cirurgia , Dermatoses do Couro Cabeludo/patologia , Dermatoses do Couro Cabeludo/cirurgia , Resultado do Tratamento , Adulto Jovem
3.
J Am Podiatr Med Assoc ; 108(4): 334-339, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30156886

RESUMO

Mycetoma cases are predominantly found in tropical regions and are a rare finding in the United States. These masses that are fungal or bacterial in origin can result in significant destruction of soft tissue and bone. We present a case of a patient who emigrated from Mexico to Indianapolis. He presented with a soft-tissue mass that was excised and ultimately found to be a eumycetoma of the hallux of his left foot. Successful treatment included surgical resection in combination with postoperative terbinafine, which was pulse dosed to decrease its impact on hepatic function.


Assuntos
Dermatoses do Pé/diagnóstico , Micetoma/diagnóstico , Adulto , Antifúngicos/uso terapêutico , Terapia Combinada , Emigrantes e Imigrantes , Dermatoses do Pé/tratamento farmacológico , Dermatoses do Pé/microbiologia , Dermatoses do Pé/cirurgia , Hallux/patologia , Humanos , Indiana , Masculino , México/etnologia , Micetoma/tratamento farmacológico , Micetoma/cirurgia , Terbinafina/uso terapêutico
4.
Int J Dermatol ; 57(5): 580-582, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29399787

RESUMO

BACKGROUND: Actinomycetoma caused by Nocardia usually responds well to antibiotics. Emerging species of Nocardia, such as N. wallacei, can be a therapeutic challenge. AIMS: Confirm the therapeutic effectivity of linezolid in multidrug resistant Nocardia Wallacei actinomycetoma. MATERIALS AND METHODS: We evaluated the medical management of an 18-year-old man with multidrug resistant actinomycetoma of the left leg caused by N. transvalensis complex treated 17 years ago with linezolid 1200 mg a day. This bacteria was recently reclassified as Nocardia Wallacei by specific molecular biology technique. RESULTS: The infection was cured after 3 months of treatment; the patient remained asymptomatic for the past 17 years. No adverse effects were found. DISCUSSION: Frequently, strains of N. transvalensis complex have aminoglycoside resistance; in this case, we highlight the effectiveness of linezolid for the successful medical management of multidrug resistant actinomycetoma. CONCLUSION: Linezolid can be an alternative for the treatment of multidrug resistant Nocardia Wallacei.


Assuntos
Antibacterianos/uso terapêutico , Micetoma/diagnóstico , Micetoma/tratamento farmacológico , Nocardiose/tratamento farmacológico , Nocardia/efeitos dos fármacos , Adolescente , Amputação Cirúrgica/métodos , Biópsia por Agulha , Progressão da Doença , Resistência a Múltiplos Medicamentos , Seguimentos , Humanos , Imuno-Histoquímica , Extremidade Inferior/fisiopatologia , Masculino , México , Testes de Sensibilidade Microbiana , Micetoma/microbiologia , Micetoma/cirurgia , Nocardia/isolamento & purificação , Nocardiose/diagnóstico , Fatores de Tempo , Resultado do Tratamento
6.
Rev. Asoc. Méd. Argent ; 127(1): 30-33, mar. 2014. ilus
Artigo em Espanhol | LILACS | ID: lil-753344

RESUMO

Presentamos el primer caso de pie de madura publicado en Argentina y realizamos una breve actualización de su diagnóstico y terapéutica.


We presented the first case of feet of Madura published in Argentine. We did a review of diagnostic and treatment.


Assuntos
Humanos , Masculino , Adulto Jovem , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Micetoma/diagnóstico , Micetoma/etiologia , Micetoma/terapia , Antibacterianos/uso terapêutico , Argentina , Diagnóstico Diferencial , Micetoma/cirurgia
7.
Clin Dermatol ; 30(4): 389-96, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22682186

RESUMO

Eumycetoma is caused by different fungi. Madurella mycetomatis, Madurella grisae, and Scedosporium apiospermum are the most common causative agents. This disease is more frequent on the lower extremities but can also be present in other areas. The diagnosis is made by direct microscopic examination and histologic study, which should show hyphae and vesicles characteristic of the fungi. Etiologic identification of the species of the fungus is sometimes difficult by culture and biopsy specimen; in these cases, molecular techniques can help to identify the infecting organism. Treatment has been with amphotericin B, which is now seldom used due to its side effects and limited success. The best therapeutic choice is surgical removal of the lesion, followed by medical treatment. This includes antifungals such as the azoles, ketoconazole and itraconazole; in resistant cases, posaconazole and voriconazole are currently recommended. In particular, the combination of terbinafine and itraconazole can elicit a good result in some cases.


Assuntos
Antifúngicos/uso terapêutico , Micetoma/tratamento farmacológico , Farmacorresistência Fúngica Múltipla/efeitos dos fármacos , Humanos , Micetoma/etiologia , Micetoma/cirurgia
8.
Int. arch. otorhinolaryngol. (Impr.) ; 16(2): 286-290, abr.-jun. 2012. ilus, tab
Artigo em Português | LILACS | ID: lil-641641

RESUMO

Introdução: Bola fúngica dos seios paranasais é uma infecção não invasiva que se caracteriza por sua cronicidade, sendo a maioria relacionada com tratamento endodôntico prévio. Acomete principalmente o seio maxilar, embora todos os seios possam ser envolvidos. O principal agente etiológico é o Aspergillus spp. A tomografia computadorizada, devido às apresentações radiológicas características, sugere o diagnóstico que é realizado definitivamente através de análises histopatológicas. O tratamento padrão-ouro é a cirurgia sinusal endoscópica com antrostomia meatal média. Objetivo: Relatar dois casos de bola fúngica dos seios paranasais e ressaltar aspectos importantes desta patologia. Relato dos Casos: Caso 1) Paciente do sexo feminino, 78 anos, apresentou-se com queixas de dor facial há 6 meses e história prévia de tratamento endodôntico. Ao exame físico constatou-se a presença de secreção purulenta em meato médio esquerdo. O Raio X apresentou velamento completo do seio maxilar esquerdo, enquanto a tomografia computadorizada mostrou lesão calcificada neste local. Realizou-se sinusotomia que evoluiu bem. Caso 2) Paciente do sexo feminino, 70 anos, procurou atendimento por história de sinusites de repetição. Ao exame físico não se percebeu nenhuma particularidade. A tomografia computadorizada, assim como a ressonância magnética, detectou espessamento da parede mucosa do seio maxilar esquerdo, além de uma massa calcificada. Realizou-se a mesma sequência de tratamento e a paciente também evoluiu bem. Considerações finais: A infecção fúngica deve ser considerada nos pacientes que se apresentam com sinusite crônica, que não respondem ao uso de antibióticos e que possuem história de manipulação endodôntica...


Introduction: Fungal ball of the sinuses is a not invasive infection that if characterizes for its chronicity, being the majority related with previous endodontic treatment. Affect mainly the breasts to maxillary; even so all the breasts can be involved. The main etiological agent is the Aspergillus spp. The computed tomography, had to characteristic the radiological presentations, suggests the diagnosis that is carried through definitively through histopathological analyses. The treatment standard-gold is the sinus surgery with average meatal antrostomy. Objective: Reporting two cases of fungal ball of the sinuses and to stand out important aspects of this pathology. Story of the Cases: Case 1) Patient of the feminine sex, 78 years old, presented itself with complaints of face pain has 6 months and previous history of endodontic treatment. To the physical examination it was evidenced purulent secretion presence in left average meatus. Ray X presented complete veiling of the breasts to maxillary left, while the computed tomography showed injury calcified in this place. Sinusotomy was become fulfilled that evolved well. Case 2) Patient of the feminine sex, 70 years old, looked attendance for history of sinusitis of repetition. To the physical examination no particularity was not perceived. The computed tomography, as well as the magnetic resonance, detected thickening of the mucous wall of the breasts to maxillary left, beyond a calcified mass. It was become fulfilled same sequence of treatment and the patient also evolved well. Final Considerations: The fungal infection must be considered in the patients who if present with chronic sinusitis, that they do not answer to the antibiotic use and that they possess history of endodontic manipulation...


Assuntos
Humanos , Feminino , Idoso , Aspergillus/patogenicidade , Micoses , Literatura de Revisão como Assunto , Seios Paranasais/fisiopatologia , Seios Paranasais/microbiologia , Sinusite Maxilar/cirurgia , Sinusite Maxilar/etiologia , Sinusite Maxilar/terapia , Tomografia Computadorizada por Raios X , Imageamento por Ressonância Magnética , Micetoma/cirurgia , Micetoma/fisiopatologia , Micetoma/terapia
12.
Rev Chilena Infectol ; 26(5): 453-6, 2009 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-19915757

RESUMO

Scedosporium species can cause colonization, superficial and deep localized infection or systemic disease, especially in immunocompromised hosts. We report a case of localized infection due to Scedosporium apiospermum in a 47 year old woman, with previous nasal surgery. She consulted for recurrent mucopurulent post-nasal discharge not responding to antibiotics. Computed tomography showed opacification of right maxillary sinus. Surgery was performed to removed abnormal tissue from sinus; biopsy revealed chronic sinusitis with aggregate of tightly packed hyphae suggestive of filamentous fungi. The microbiology fungal culture reported Scedosporium apiospermum.


Assuntos
Imunocompetência , Micetoma/microbiologia , Rinite/microbiologia , Scedosporium/isolamento & purificação , Sinusite/microbiologia , Doença Crônica , Feminino , Humanos , Pessoa de Meia-Idade , Micetoma/diagnóstico , Micetoma/cirurgia , Rinite/diagnóstico , Rinite/cirurgia , Sinusite/diagnóstico , Sinusite/cirurgia
13.
Rev. chil. infectol ; Rev. chil. infectol;26(5): 453-456, oct. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-532138

RESUMO

Scedosporium species can cause colonization, superficial and deep localized infection or systemic disease, espe-cially in irnmunocompromised hosts. We report a case of localized infection due to Scedosporium apiospermum in a 47 year oíd woman, with previous nasal surgery. She consulted for recurrent mucopurulent post-nasal discharge not responding to antibiotics. Computed tomography showed opacification of right maxillary sinus. Surgery was performed to removed abnormal tissue from sinus; biopsy revealed chronic sinusitis with aggregate of tightly packed hyphae suggestive of filamentous fungi. The microbiology fungal culture reported Scedosporium apiospermum.


Las infecciones por Scedosporium sp pueden traducirse en colonización, infecciones localizadas superficiales y profundas, o enfermedad diseminada. Presentamos un caso clínico de infección rinosinusal por Scedosporium apiospermum en una paciente de 47 años, con antecedente de cirugía por cuerpo extraño en la fosa nasal derecha. Consultó por descarga posterior muco-purulenta y recurrente, sin respuesta a tratamiento antibacteriano. Las imágenes de cavidades paranasales mostraron opacidad del seno maxilar derecho. Se realizó cirugía de remoción de contenido sinusal cuyo estudio histológico reveló sinusitis crónica erosiva, colonias de hongos con morfología sugerente de hongo filamentoso y desarrollo de S. apiospermum en el cultivo.


Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Imunocompetência , Micetoma/microbiologia , Rinite/microbiologia , Scedosporium/isolamento & purificação , Sinusite/microbiologia , Doença Crônica , Micetoma/diagnóstico , Micetoma/cirurgia , Rinite/diagnóstico , Rinite/cirurgia , Sinusite/diagnóstico , Sinusite/cirurgia
14.
Int J Dermatol ; 48(4): 401-3, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19335427

RESUMO

We report a 21-year-old farmer with a 4-year history of a nodular plaque with fistulas and induration of adjacent skin. The lesion had been treated surgically at another hospital, but recurred 2 years later. Black, charcoal-like grains were observed draining through the fistulas. A biopsy specimen showed brown grains with filaments in an abscess surrounded by macrophages, giant cells, and lymphocytes. Culture demonstrated small white colonies of Madurella mycetomatis. The patient was treated with itraconazole for 6 months, followed by surgery. TNP was initiated in the immediate post-operative period, and copious granulation tissue was observed within 1 week. Autologous skin grafting was performed, and itraconazole was continued for an additional 3 months. Although necrosis of the graft ensued, the functional result was acceptable. The patient appeared free of disease at 18 months of follow-up. Eumycotic mycetoma is an infectious and inflammatory process that occurs after traumatic inoculation of fungi through the skin. Surgery is the treatment of choice, but successful reconstruction may be challenging and recurrence is common. Topical negative pressure (TNP) promotes the formation of granulation tissue, which facilitates closure of deep wounds and chronic ulcers. This case illustrates that eumycotic mycetoma is difficult to treat. Whether TNP contributed to the successful outcome cannot be proven but, given the generally poor response of eumycetoma to therapy, we suggest that the role of TNP in the management of this disease merits attention.


Assuntos
Antifúngicos/administração & dosagem , Itraconazol/administração & dosagem , Madurella , Micetoma/tratamento farmacológico , Micetoma/cirurgia , Tratamento de Ferimentos com Pressão Negativa , Terapia Combinada , Humanos , Masculino , Micetoma/patologia , Adulto Jovem
16.
Rev Argent Microbiol ; 38(1): 13-8, 2006.
Artigo em Espanhol | MEDLINE | ID: mdl-16784127

RESUMO

This work presents clinical, microbiological and outcome data collected from 76 patients with mycetomas at the Muñiz Hospital from 1989 to 2004. Forty-nine patients were male and 27 female; the mean age was 43.4 years. The majority of the patients acquired the infection in Argentina: the most affected provinces were Santiago del Estero with 31 cases, and Chaco with 11; 8 cases came from other countries (Bolivia 6 and Paraguay 2). The mean evolution of the disease was 9.2 years. The most frequently observed sites were: feet 63 cases, ankles 3, and knees 2. Forty-eight patients had bone lesions and 5, adenomegalies. The following etiological agents were identified: Madurella grisea 29 cases, Actinomadura madurae 26, Scedosporium apiospermum 5, Nocardia brasiliensis 5, Acremonium spp. 4 (Acremonium falciforme 2, Acremonium kiliense 1, Acremonium recifei 1), Madurella mycetomatis 3, Fusarium solani 2, Nocardia asteroides 1 and Streptomyces somaliensis 1. The main drugs used in the treatments were ketoconazole and itraconazole for maduromycotic mycetomas, and cotrimoxazole associated with ciprofloxacin or amikacin for actinomycetic mycetoma. Six patients had to undergo amputation, 25 cases achieved complete clinical remission and 34 showed remarkable improvement.


Assuntos
Infecções por Actinomycetales/epidemiologia , Micetoma/epidemiologia , Actinomycetales/isolamento & purificação , Infecções por Actinomycetales/tratamento farmacológico , Infecções por Actinomycetales/microbiologia , Infecções por Actinomycetales/cirurgia , Adolescente , Adulto , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/epidemiologia , Doenças dos Trabalhadores Agrícolas/microbiologia , Doenças dos Trabalhadores Agrícolas/cirurgia , Amputação Cirúrgica , Antibacterianos/uso terapêutico , Antifúngicos/uso terapêutico , Argentina/epidemiologia , Terapia Combinada , Feminino , Dermatoses do Pé/tratamento farmacológico , Dermatoses do Pé/epidemiologia , Dermatoses do Pé/microbiologia , Dermatoses do Pé/cirurgia , Fusarium , Humanos , Madurella/efeitos dos fármacos , Madurella/isolamento & purificação , Masculino , Pessoa de Meia-Idade , Fungos Mitospóricos/isolamento & purificação , Micetoma/tratamento farmacológico , Micetoma/microbiologia , Micetoma/cirurgia , Nocardiose/tratamento farmacológico , Nocardiose/epidemiologia , Nocardiose/microbiologia , Nocardiose/cirurgia , Osteíte/tratamento farmacológico , Osteíte/etiologia , Osteíte/microbiologia , Osteíte/cirurgia , Indução de Remissão , Estudos Retrospectivos , Resultado do Tratamento
17.
Rev. argent. microbiol ; Rev. argent. microbiol;38(1): 13-18, ene.-mar. 2006. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-634513

RESUMO

Se presentan las características clínicas, microbiológicas y los resultados del tratamiento de 76 casos de micetomas observados en el período 1989-2004 en el Hospital Muñiz. Cuarenta y nueve fueron varones y 27 mujeres, con una edad promedio de 43,4 años. La mayor parte de los pacientes adquirió la infección en nuestro país, las provincias más afectadas fueron Santiago del Estero con 31 casos y el Chaco con 11; 8 enfermos procedían del exterior, 6 de Bolivia y 2 de Paraguay. El promedio de evolución de la enfermedad fue de 9,2 años. Las localizaciones más comunes fueron las de los miembros inferiores: pies 63, tobillos 3 y rodillas 2. Se comprobó compromiso óseo en 48 casos y adenomegalias en 5. Fueron identificados los siguientes agentes causales: Madurella grisea 29 casos, Actinomadura madurae 26, Scedosporium apiospermum 5, Nocardia brasiliensis 5, Acremoniun spp. 4 (Acremonium falciforme 2, Acremonium kiliense 1 y Acremonium recifei 1), Madurella mycetomatis 3, Fusarium solani 2, Nocardia asteroides y Streptomyces somaliensis 1 caso cada uno. Los tratamientos más frecuentemente utilizados fueron ketoconazol o itraconazol en los micetomas maduromicósicos y la asociación de cotrimoxazol con ciprofloxacina o amicacina en los micetomas actinomicéticos. La amputación del miembro afectado se realizó en 6 casos, 25 pacientes alcanzaron la remisión clínica completa y 34 presentaron mejorías importantes.


This work presents clinical, microbiological and outcome data collected from 76 patients with mycetomas at the Muñiz Hospital from 1989 to 2004. Forty-nine patients were male and 27 female; the mean age was 43.4 years. The majority of the patients acquired the infection in Argentina: the most affected provinces were Santiago del Estero with 31 cases, and Chaco with 11; 8 cases came from other countries (Bolivia 6 and Paraguay 2). The mean evolution of the disease was 9.2 years. The most frequently observed sites were: feet 63 cases, ankles 3, and knees 2. Forty-eight patients had bone lesions and 5, adenomegalies. The following etiological agents were identified: Madurella grisea 29 cases, Actinomadura madurae 26, Scedosporium apiospermum 5, Nocardia brasiliensis 5, Acremonium spp. 4 (Acremonium falciforme 2, Acremonium kiliense 1, Acremonium recifei 1), Madurella mycetomatis 3, Fusarium solani 2, Nocardia asteroides 1 and Streptomyces somaliensis 1. The main drugs used in the treatments were ketoconazole and itraconazole for maduromycotic mycetomas, and cotrimoxazole associated with ciprofloxacin or amikacin for actinomycetic mycetoma. Six patients had to undergo amputation, 25 cases achieved complete clinical remission and 34 showed remarkable improvement.


Assuntos
Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infecções por Actinomycetales/epidemiologia , Micetoma/epidemiologia , Amputação Cirúrgica , Infecções por Actinomycetales/tratamento farmacológico , Infecções por Actinomycetales/microbiologia , Infecções por Actinomycetales/cirurgia , Actinomycetales/isolamento & purificação , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/epidemiologia , Doenças dos Trabalhadores Agrícolas/microbiologia , Doenças dos Trabalhadores Agrícolas/cirurgia , Antibacterianos/uso terapêutico , Antifúngicos/uso terapêutico , Argentina/epidemiologia , Terapia Combinada , Fusarium , Dermatoses do Pé/tratamento farmacológico , Dermatoses do Pé/epidemiologia , Dermatoses do Pé/microbiologia , Dermatoses do Pé/cirurgia , Madurella/efeitos dos fármacos , Madurella/isolamento & purificação , Fungos Mitospóricos/isolamento & purificação , Micetoma/tratamento farmacológico , Micetoma/microbiologia , Micetoma/cirurgia , Nocardiose/tratamento farmacológico , Nocardiose/epidemiologia , Nocardiose/microbiologia , Nocardiose/cirurgia , Osteíte/tratamento farmacológico , Osteíte/etiologia , Osteíte/microbiologia , Osteíte/cirurgia , Indução de Remissão , Estudos Retrospectivos , Resultado do Tratamento
18.
Arch. argent. dermatol ; 55(2): 71-74, mar.-abr. 2005. ilus
Artigo em Espanhol | BINACIS | ID: bin-1443

RESUMO

Comunicamos un caso de micetoma causado por Actinomadura madurae con el hallazgo de los granos en la biopsia de piel y desarrollo del agente etiológico por cultivo del material obtenido por biopsia quirúrgica. Destacamos la utilidad de la resonancia magnética nuclear en la evaluación previa al acto quirúrgico, especialmente en cuanto al compromiso osteoarticular (AU)


Assuntos
Humanos , Pessoa de Meia-Idade , Feminino , Micetoma/diagnóstico , Infecções por Actinomycetales/diagnóstico , Micetoma/tratamento farmacológico , Micetoma/cirurgia , Imageamento por Ressonância Magnética , Infecções por Actinomycetales/tratamento farmacológico , Infecções por Actinomycetales/cirurgia
20.
Rev Inst Med Trop Sao Paulo ; 46(1): 43-6, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15057335

RESUMO

Four cases of respiratory tract intracavitary colonization (fungus ball) due to Scedosporium apiospermum (teleomorph, Pseudallescheria boydii) are reported. The need for a careful search for anneloconidia, in order to establish the etiologic diagnosis in the clinical specimen by microscopy, is emphasized.


Assuntos
Pneumopatias Fúngicas/microbiologia , Micetoma/diagnóstico , Scedosporium/isolamento & purificação , Adulto , Idoso , Feminino , Humanos , Pneumopatias Fúngicas/diagnóstico , Pneumopatias Fúngicas/cirurgia , Masculino , Pessoa de Meia-Idade , Micetoma/cirurgia
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