RESUMO

Free radicals have been hypothesized to play a key role in the evolution of periventricular leukomalacia, although direct evidence of oxidative injury in the human infant is lacking. This case report is the first to demonstrate a marked elevation in the levels of lipid and protein oxidative products in the cerebrospinal fluid during the evolution of periventricular leukomalacia in a premature infant with meningitis.

Assuntos

Recém-Nascido Prematuro , Leucomalácia Periventricular/líquido cefalorraquidiano , Peroxidação de Lipídeos , Meningites Bacterianas/líquido cefalorraquidiano , Estresse Oxidativo , Biomarcadores , Feminino , Humanos , Recém-Nascido , Leucomalácia Periventricular/microbiologia , Leucomalácia Periventricular/patologia , Imageamento por Ressonância Magnética , Meningites Bacterianas/complicações