RESUMO
The aim of this study was to evaluate the effect of 1% sodium hypochlorite and five intracanals medications on Candida albicans harvested inside root canals. The contaminated canals were irrigated with sterile saline solution and then treated as follows: (i) filled with Calen paste (calcium hydroxide/ glycol polyethylene paste); (ii) filled with camphorated paramonochloro phenol (CPMC); (iii) filled with 2% iodine-iodate solution; (iv) filled with tricresol formalin; (v) filled with Calen and CPMC pastes; (vi) irrigation with 1% sodium hypochlorite and filled with no intracanal medication; and (vii) no intracanal medication was used. Canal access and the apical foramen were then sealed with Cavit and the roots were stored in a humid chamber at 37 +/- 1 degree C for 14 days. The canals were reinstrumented and irrigated with sterile saline solution. Sterile paper points were used to transfer the root canal contents to test tubes containing sterile saline solution. Part of the suspension was harvested in Sabouraud dextrose agar with chloramphenicol and incubated at 37 +/- 1 degree C for 48 h. CPMC was effective in 100% of the samples followed in decreasing order of effectiveness by calcium hydroxide with CPMC (70% effective), 1% sodium hypochlorite (70% effective) (p < 0.05), tricresol formalin (60% effective), 2% iodine-iodate solution (50% effective), calcium hydroxide paste (30% effective), and saline + no intracanal medication.
Assuntos
Anti-Infecciosos Locais/farmacologia , Candida albicans/efeitos dos fármacos , Cavidade Pulpar/microbiologia , Formaldeído/análogos & derivados , Irrigantes do Canal Radicular/farmacologia , Hipoclorito de Sódio/farmacologia , Hidróxido de Cálcio/farmacologia , Sulfato de Cálcio/farmacologia , Cânfora/farmacologia , Clorofenóis/farmacologia , Cresóis/farmacologia , Cimentos Dentários , Combinação de Medicamentos , Formaldeído/farmacologia , Humanos , Umidade , Iodatos/farmacologia , Compostos de Iodo/farmacologia , Polietilenoglicóis/farmacologia , Polivinil/farmacologia , Materiais Restauradores do Canal Radicular/farmacologia , Estatística como Assunto , Tensoativos/farmacologia , Temperatura , Óxido de Zinco/farmacologiaRESUMO
The mutans group of streptococci is considered to play a key role in the etiology of dental caries. We have evaluated the ability of different substances to prevent dental plaque formation without affecting Streptococcus sobrinus viability. Viable organisms were detected as CFU/mL in agar plates and bacterial adherence was assessed by dry weight. We studied 23 compounds and we demonstrated that phenyl salicylate, phenylmercuric nitrate and potassium iodate are more effective to inhibit adhesion without showing antibacterial activity.