RESUMO
Introducción: Las intervenciones quirúrgicas de hernias son uno de los procedimientos que más frecuente realizan los cirujanos. Objetivo: Caracterizar a los pacientes a los que les fue realizada la técnica quirúrgica de hernioplastia inguinal según la técnica de Jean Rives modificada. Métodos: Se realizó un estudio descriptivo retrospectivo de corte longitudinal en el Hospital Universitario Arnaldo Milián Castro de Santa Clara en el período de enero del 2011 a diciembre del 2021. El universo de trabajo estuvo representado por la población de pacientes con el diagnóstico de hernias inguinocrurales, a los cuales les fue efectuada dicha técnica quirúrgica. La muestra estuvo conformada por 194 pacientes. Resultados: Predominó el sexo masculino 103 (53,1 por ciento) y los pacientes mayores de 60 años 99 (51,0 por ciento). La localización más frecuente de la hernia fue la zona inguinal derecha 146 (75,3 por ciento) para ambos sexos, masculino 81 (41,8 por ciento) y femenino 65 (33,5 por ciento) respectivamente. Prevalecieron las hernias inguinales primarias 96 (49,5 por ciento), directas 70 (36,1 por ciento); en el sexo masculino preponderaron las indirectas 61 (31,4 por ciento). Predominaron las complicaciones posoperatorias en las cirugías de urgencias 10 (5,0 por ciento). El seroma 4 (2,0 por ciento), la orquitis 3 (1,5 por ciento) y la recidiva herniaria 3 (1,5 por ciento) fueron las complicaciones más comunes. Conclusiones: La técnica de hernioplastia inguinocrural de Jean Rives modificada es efectiva para los pacientes masculinos mayores de 60 años con hernias inguinales primarias, directas e indirectas. Las posibles complicaciones posoperatorias fueron en las intervenciones quirúrgicas de urgencia, donde el seroma y la orquitis fueron las más frecuentes. La recidiva tuvo una baja tasa con respecto a otros tipos de hernioplastias(AU)
Introduction: Hernia surgical interventions are one of the procedures most frequently performed by surgeons. Objective: To characterize the patients who underwent the surgical technique of inguinal hernioplasty based on the modified Jean Rives technique. Methods: A retrospective, descriptive and longitudinal study was carried out in Hospital Universitario Arnaldo Milián Castro, of Santa Clara City, central Cuba, in the period from January 2011 to December 2021. The study universe was represented by the population of patients diagnosed with inguinocrural hernias who underwent this surgical technique. The sample consisted of 194 patients. Results: There was a predominance of the male sex, accounting for 103 (53.1 percent); as well as of patients over 60 years of age, accounting for 99 (51.0 percent). The most frequent location of the hernia was the right inguinal area, represented by 146 cases (75.3 percent) for both sexes, accounting for 81 (41.8 percent) and 65 (33.5 percent) for males and females, respectively. Primary inguinal hernias predominated, represented by 96 cases (49.5 percent); as well as direct hernias, accounting for 70 cases (36.1 percent). In the male sex, indirect hernias predominated, accounting for 61 cases (31.4 percent). Postoperative complications predominated in emergency surgery, represented by 10 cases (5.0 percent). Seroma (4; 2.0 percent), orchitis (3; 1.5 percent) and hernia recurrence (3; 1.5 percent) were the most common complications. Conclusions: The modified Jean Rives inguinocrural hernioplasty technique is effective for male patients older than 60 years with primary, direct and indirect inguinal hernias. Potential postoperative complications occurred in emergency surgery, in which cases seroma and orchitis were the most frequent ones. Recurrence had a low rate compared to other types of hernioplasties(AU)
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Herniorrafia/métodos , Hérnia Inguinal/etiologia , Epidemiologia Descritiva , Estudos RetrospectivosRESUMO
Retroperitoneal lipomas are extremely rare with few cases reported so far in the literature. They can reach different sizes and present with a variety of symptoms. The differential diagnosis is mainly with well-differentiated liposarcoma (WDLPS). We present a 34-year-old woman with a retroperitoneal lipoma herniating through the inguinal canal into the proximal thigh. The patient underwent complete oncological resection using a Karakousis's abdominoinguinal incision. Retroperitoneal lipomas are a very rare condition and sometimes require resections technically challenging. MDM2 amplification is critical for its differential diagnosis with WDLPS.
Assuntos
Hérnia Inguinal/diagnóstico por imagem , Lipoma/diagnóstico por imagem , Neoplasias Retroperitoneais/diagnóstico por imagem , Adulto , Diagnóstico Diferencial , Feminino , Hérnia Inguinal/etiologia , Hérnia Inguinal/patologia , Hérnia Inguinal/cirurgia , Humanos , Lipoma/complicações , Lipoma/patologia , Lipoma/cirurgia , Lipossarcoma/diagnóstico , Neoplasias Retroperitoneais/complicações , Neoplasias Retroperitoneais/patologia , Neoplasias Retroperitoneais/cirurgia , Tomografia Computadorizada por Raios X , Carga TumoralRESUMO
BACKGROUND: Surgical management of an asymptomatic inguinal hernia is controversial but given that most of the patients will develop symptoms, the hernioplasty seems to be a reasonable option. We aimed to compare postoperative outcomes after transabdominal preperitoneal (TAPP) repair between patients with symptomatic bilateral hernia (SBH) and patients with one symptomatic hernia and an asymptomatic contralateral hernia (ACH). METHODS: A consecutive series of patients undergoing bilateral laparoscopic TAPP from July 2014 to June 2018 were included. Symptomatic hernia was defined as a groin bulge associated to pain and altered patient's daily activities. Patients were divided into two groups, those with SBH and those with one symptomatic hernia in whom an ACH was diagnosed by physical examination or ultrasound when clinical assessment was inconclusive. Demographics, operative, and postoperative outcomes were compared. Quality of life (QoL) was assessed before and after surgery in both groups. RESULTS: A total of 305 bilateral TAPP repairs were included; 102 (33, 4%) patients had SBH and 203 (66, 6%) had ACH. There were no significant differences between groups regarding age, gender, body mass index, active smoking, and comorbidities. Operative time (SBH: 125 vs. ACH: 132 min, p = 0.13) and overall 30-day morbidity were similar between groups (SBH: 14, 7% vs. ACH: 13, 8%, p = 0.82). After a mean follow-up of 30 (10-48) months, the recurrence rate was 1, 4% and 2, 2% in SBH and ACH, respectively (p = 0.53). QoL after surgery improved significantly and similarly in both groups. CONCLUSION: Bilateral laparoscopic TAPP in the setting of an asymptomatic hernia did not increase morbidity and had similar outcomes when compared to patients with bilateral symptoms. A comprehensive preoperative evaluation of the contralateral groin should be routinely performed, mainly by physical examination, and a bilateral repair may be proposed if an asymptomatic contralateral hernia is detected.
Assuntos
Hérnia Inguinal/cirurgia , Herniorrafia/métodos , Laparoscopia/métodos , Qualidade de Vida , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Assintomáticas , Comorbidade , Feminino , Virilha/cirurgia , Hérnia Inguinal/epidemiologia , Hérnia Inguinal/etiologia , Herniorrafia/efeitos adversos , Humanos , Laparoscopia/efeitos adversos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Recidiva , Resultado do Tratamento , Adulto JovemRESUMO
PURPOSE: Relying solely on in-person encounters to assess long-term outcomes of hernia repair leads to substantial loss of information and patients lost-to-follow-up, hindering research and quality improvement initiatives. We aimed to determine if inguinal hernia recurrences could be assessed using the Ventral Hernia Recurrence Inventory (VHRI), a previously existing patient-reported outcome (PRO) tool that can be administered through the telephone and has already been validated for diagnosing ventral hernia recurrence. METHODS: A prospective, multicentric comparative study was conducted. Adult patients from two centers (United States and Brazil) at least 1 year after open or minimally invasive inguinal hernia repair were asked to answer the questions of the VHRI in relation to their prior repair. A physical exam was then performed by a blinded surgeon. Testing characteristics and diagnostic performance of the PRO were calculated. Patients with suspected recurrences were preferentially recruited. RESULTS: 128 patients were enrolled after 175 repairs. All patients answered the VHRI and were further examined, where a recurrence was present in 32% of the repairs. Self-reported bulge and patient perception of a recurrence were highly sensitive (84-94%) and specific (93-94%) for the diagnosis of an inguinal hernia recurrence. Test performance was similar in the American and Brazilian populations despite several baseline differences in demographic and clinical characteristics. CONCLUSION: The VHRI can be used to assess long-term inguinal hernia recurrence and should be reestablished as the Hernia Recurrence Inventory (HRI). Its implementation in registries, quality improvement efforts, and research could contribute to improving long-term follow-up rates in hernia patients.
Assuntos
Hérnia Inguinal/etiologia , Hérnia Inguinal/cirurgia , Herniorrafia , Medidas de Resultados Relatados pelo Paciente , Adulto , Idoso , Brasil , Feminino , Seguimentos , Hérnia Inguinal/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Recidiva , Fatores de Risco , Estados UnidosRESUMO
Complete duplication of testicular veins is a rare phenomenon. However, a few cases of duplication of gonadal veins have been reported. Here, I report a case of unusual formation and termination of the right testicular vein in an adult male cadaver. Five veins arose from the pampinniform plexus and entered the abdomen through the deep inguinal ring. The most medial among the five was large (3 mm in diameter) and it continued as a testicular vein and opened into the right edge of the inferior vena cava, 1 cm above the union of the common iliac veins. The other four veins were about 1 mm in diameter and they united to form two veins in front of the lower part of the right psoas and iliacus muscles (about 2 cm above the deep inguinal ring) and the two veins united to form upper testicular vein, 4 cm above the deep inguinal ring. This testicular vein was 3 mm in diameter and it opened into the inferior vena cava, 4 cm above the union of common iliac veins. Having five veins at deep inguinal ring might increase the chances of varicocele and decrease the chances of indirect inguinal hernia.
La duplicación completa de las venas testiculares es un fenómeno raro. Sin embargo, se han reportado algunos casos de duplicación de venas gonadales. En el presente trabajo se informa un caso de formación y terminación inusual de la vena testicular derecha en un cadáver de un hombre adulto. Cinco venas surgieron del plexo pampiniforme y penetraron en el abdomen a través del anillo inguinal profundo. El más medial entre los cinco fue de gran tamaño (3 mm de diámetro) y continuó como una vena testicular y se abrió hacia el margen derecho de la vena cava inferior, 1 cm por encima de la unión de las venas ilíacas comunes. Las cuatro venas restantes eran de 1 mm de diámetro aproximadamente, y se unieron para formar dos venas frente a la parte inferior de los músculos psoas e ilíaco derechos (aproximadamente 2 cm por encima del anillo inguinal profundo). Se unieron dos venas para formar la vena testicular superior, la cual medía 3 mm de diámetro y se abría hacia la vena cava inferior, 4 cm por encima de la unión de las venas ilíacas comunes. Cinco venas en el anillo inguinal profundo podrían aumentar las posibilidades de varicocele y disminuir las posibilidades de una hernia inguinal indirecta.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Veias/anormalidades , Canal Inguinal/irrigação sanguínea , Testículo/irrigação sanguínea , Varicocele/etiologia , Veia Cava Inferior/anormalidades , Gônadas/irrigação sanguínea , Hérnia Inguinal/etiologiaAssuntos
Líquido Ascítico , Hérnia Inguinal/etiologia , Canal Inguinal , Falência Renal Crônica/terapia , Diálise Peritoneal Ambulatorial Contínua/efeitos adversos , Hidrocele Testicular/etiologia , Idoso , Hérnia Inguinal/diagnóstico , Hérnia Inguinal/cirurgia , Herniorrafia , Humanos , Masculino , Hidrocele Testicular/diagnóstico , Hidrocele Testicular/cirurgiaRESUMO
ABSTRACT Background: New findings point out that the mechanism of formation of the hernias can be related to the collagenous tissues, under activity of aggressive agents such as the tobacco, alcohol and diabetes. Aim: To analyze the collagen present in the cremaster muscle in patients with inguinal hernias, focusing the effect of tobacco, alcohol, and diabetes. Methods: Fifteen patients with inguinal hernia divided in three groups were studied: group I (n=5) was control; group II (n=5) were smokers and/or drinkers; and group III (n=5) had diabetes mellitus. All subjects were underwent to surgical repair of the inguinal hernias obeying the same pre, intra and postoperative conditions. During surgery, samples of the cremaster muscle were collected for analysis in polarized light microscopy, collagen morphometry and protein. Results: The area occupied by the connective tissue was higher in groups II and III (p<0.05). The collagen tissue occupied the majority of the samples analyzed in comparison to the area occupied by muscle cells. The content of total protein was higher in groups II and III compared to the control group (p<0.05). Conclusion: The tobacco, alcohol and diabetes cause a remodel the cremaster muscle, leading to a loss of support or structural change in this region, which may enhance the occurrences and damage related to inguinal hernias.
RESUMO Racional: Estudos recentes sinalizam que o mecanismo de formação das hérnias pode estar relacionado aos tecidos colagenosos, sob a ação de agentes agressores como o tabaco, o álcool e o diabete. Objetivo: Avaliar o colágeno presente no músculo cremaster em pacientes com hérnias inguinais enfocando o efeito do tabaco, álcool e diabete. Métodos: Foram estudados 15 pacientes com hérnias inguinais divididos em: grupo I (n=5) controles; grupo II (n=5) indivíduos fumantes e/ou etilistas; e grupo III (n=5) indivíduos que apresentavam diabete melito. Todos foram submetidos à correção cirúrgica das hérnias inguinais obedecendo às mesmas condições pré, intra e pós-operatórias. Durante o procedimento cirúrgico, amostras do músculo cremaster foram coletadas para análises em microscopia de luz polarizada, morfometria do colágeno e de proteínas. Resultados: A área ocupada por tecido conjuntivo foi maior nos grupos II e III (p<0,05). O tecido colágeno ocupou a maior parte das amostras analisadas, em comparação à área ocupada pelas células musculares. O conteúdo de proteínas totais foi maior nos grupos II e III, quando comparado com o grupo controle (p<0,05). Conclusão: O tabaco, o álcool e o diabete ocasionam remodelação no músculo cremaster, levando à perda de suporte ou alteração estrutural nesta região, podendo intensificar as ocorrências e os danos relacionados às hérnias inguinais.
Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Adulto Jovem , Consumo de Bebidas Alcoólicas/efeitos adversos , Fumar/efeitos adversos , Colágeno/análise , Músculos Abdominais/química , Complicações do Diabetes/etiologia , Hérnia Inguinal/etiologia , Consumo de Bebidas Alcoólicas/metabolismo , Fumar/metabolismo , Colágeno/biossíntese , Músculos Abdominais/metabolismo , Complicações do Diabetes/metabolismo , Hérnia Inguinal/metabolismoRESUMO
Background: New findings point out that the mechanism of formation of the hernias can be related to the collagenous tissues, under activity of aggressive agents such as the tobacco, alcohol and diabetes. Aim: To analyze the collagen present in the cremaster muscle in patients with inguinal hernias, focusing the effect of tobacco, alcohol, and diabetes. Methods: Fifteen patients with inguinal hernia divided in three groups were studied: group I (n=5) was control; group II (n=5) were smokers and/or drinkers; and group III (n=5) had diabetes mellitus. All subjects were underwent to surgical repair of the inguinal hernias obeying the same pre, intra and postoperative conditions. During surgery, samples of the cremaster muscle were collected for analysis in polarized light microscopy, collagen morphometry and protein. Results: The area occupied by the connective tissue was higher in groups II and III (p<0.05). The collagen tissue occupied the majority of the samples analyzed in comparison to the area occupied by muscle cells. The content of total protein was higher in groups II and III compared to the control group (p<0.05). Conclusion: The tobacco, alcohol and diabetes cause a remodel the cremaster muscle, leading to a loss of support or structural change in this region, which may enhance the occurrences and damage related to inguinal hernias.
Racional: Estudos recentes sinalizam que o mecanismo de formação das hérnias pode estar relacionado aos tecidos colagenosos, sob a ação de agentes agressores como o tabaco, o álcool e o diabete. Objetivo: Avaliar o colágeno presente no músculo cremaster em pacientes com hérnias inguinais enfocando o efeito do tabaco, álcool e diabete. Métodos: Foram estudados 15 pacientes com hérnias inguinais divididos em: grupo I (n=5) controles; grupo II (n=5) indivíduos fumantes e/ou etilistas; e grupo III (n=5) indivíduos que apresentavam diabete melito. Todos foram submetidos à correção cirúrgica das hérnias inguinais obedecendo às mesmas condições pré, intra e pós-operatórias. Durante o procedimento cirúrgico, amostras do músculo cremaster foram coletadas para análises em microscopia de luz polarizada, morfometria do colágeno e de proteínas. Resultados: A área ocupada por tecido conjuntivo foi maior nos grupos II e III (p<0,05). O tecido colágeno ocupou a maior parte das amostras analisadas, em comparação à área ocupada pelas células musculares. O conteúdo de proteínas totais foi maior nos grupos II e III, quando comparado com o grupo controle (p<0,05). Conclusão: O tabaco, o álcool e o diabete ocasionam remodelação no músculo cremaster, levando à perda de suporte ou alteração estrutural nesta região, podendo intensificar as ocorrências e os danos relacionados às hérnias inguinais.
Assuntos
Músculos Abdominais/química , Consumo de Bebidas Alcoólicas/efeitos adversos , Colágeno/análise , Complicações do Diabetes/etiologia , Hérnia Inguinal/etiologia , Fumar/efeitos adversos , Músculos Abdominais/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Consumo de Bebidas Alcoólicas/metabolismo , Colágeno/biossíntese , Complicações do Diabetes/metabolismo , Hérnia Inguinal/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Fumar/metabolismo , Adulto JovemRESUMO
Existe evidencia de asociación de alteraciones de la matriz colágena en sujetos con hernia inguinal (HI). El objetivo de este estudio fue determinar la existencia de alteraciones en la expresión de MMP2 y TIMP2 en sujetos con HI primaria. Estudio de casos y controles, realizado en los Servicios de Cirugía y de Urgencias del Hospital Regional de Temuco entre 2009-2010. Se incluyeron pacientes con HI primaria mayores de 15 años, sin restricción de género (casos), e Individuos sin hernias, mayores de 15 años, intervenidos por apendicitis aguda (controles). Se excluyeron portadores de condiciones predisponentes al desarrollo de hernias de pared abdominal. La variable resultado fue determinación de MMP2 y TIMP2 mediante inmunohitoquímica (IHQ). Otras variables de interés estudiadas fueron: hábito tabáquico, antecedente familiar de hernia, historia de estreñimiento, peso, estatura e índice de masa corporal (IMC). Se utilizó estadística descriptiva; analítica y modelos de regresión logística. Se estudiaron 21 casos y 20 controles. El 73 por ciento correspondió a hombres. La edad promedio fue 55,3+/-18,9 y 38,9+/-16,9 para casos y controles respectivamente. No se observaron diferencias estadísticamente significativas en las variables sexo, estatura, peso, IMC y hábito tabáquico entre casos y controles. Se verificaron diferencias significativas en las variables, antecedente familiar de hernia e historia de estreñimiento (más frecuentes en casos). La tinción IHQ de MMP2, fue mayor en los casos (53,4 por ciento vs. 40,0 por ciento; p=0,5068), y la de TIMP2, fue mayor en los controles (35,0 por ciento vs. 23,8 por ciento; p=0, 7333). El análisis multivariado descartó confundentes. Con la metodología utilizada no se verificó asociación entre alteración de los mecanismos de degradación del colágeno, manifestados en la expresión de MMP2 y TIMP2, con el desarrollo de HI primaria.
There is some evidence of association b collagen matrix alterations in patients with inguinal hernia (IH). The aim of this study was to determine the existence of alterations in the expression of MMP2 and TIMP2 in patients with primary IH. Case-control study conducted in the Department of Surgery and Emergency of Temuco Regional Hospital in 2009-2010 periods. We included subjects with primary IH over 15 years, without gender restriction (cases) and subjects without hernias, aged 15, underwent surgery for acute appendicitis (controls). Patients with conditions predisposing to the development of abdominal wall hernias were excluded. End point was determination of MMP2 and TIMP2 by Immunohistochemistry (IHC). Other studied variables were: smoking, family history of hernia, history of constipation, weight, height and body mass index (BMI). Descriptive statistics, analytical and logistic regression models were used. 21 cases and 20 controls were studied. 73 percent were men. The average age was 55.3+/-18.9 and 38.9+/-16.9 for cases and controls respectively. There were no statistically significant differences in the variables sex, height, weight, BMI and smoking between cases and controls. Significant difference was found in the variables, family history of hernia and history of constipation (more common in cases). IHC staining of MMP2 was higher in cases (53.4 percent vs. 40.0 percent, p=0.5068) and IHC of TIMP2 was higher in controls (35.0 percent vs. 23.8 percent, p=0.7333). Multivariate analysis discarded confounders. With the methodology used has not been tested association between alteration of mechanisms of collagen degradation, manifested in MMP2 and TIMP2 expression with primary IH development.
Assuntos
Feminino , Pessoa de Meia-Idade , Colágeno Tipo I/metabolismo , Hérnia Inguinal/enzimologia , /metabolismo , /metabolismo , Índice de Massa Corporal , Estudos de Casos e Controles , Hérnia Inguinal/etiologia , Imuno-Histoquímica , Modelos Logísticos , Pele/metabolismoRESUMO
BACKGROUND: traumatic hernias of the abdominal wall caused by handlebars are a rare type of hernia but with clinical and therapeutic connotations of great interest. CLINICAL CASES: we report 3 new cases, 1 case with diagnosis on admission and emergency treatment by open approach, and 2 with a diagnostic delay of 6 months and operated on a scheduled basis using totally extraperitoneal laparoscopy. We provide here an update. DISCUSSION: the diagnosis must be completed with a CT to rule out visceral lesions. Treatment depends on the severity of their presentation. In severe associated injuries or urgent situations surgery should be the norm. In mild cases without other injury laparoscopic surgery may be indicated. With this study, we hope to augment the knowledge on this kind of hernia, and leading to early diagnosis and treatment.
Assuntos
Traumatismos Abdominais/complicações , Ciclismo/lesões , Hérnia Inguinal/etiologia , Hérnia Ventral/etiologia , Ferimentos não Penetrantes/complicações , Acidentes por Quedas , Adolescente , Diagnóstico Tardio , Hérnia Inguinal/diagnóstico , Hérnia Inguinal/cirurgia , Hérnia Ventral/diagnóstico , Hérnia Ventral/cirurgia , Herniorrafia , Humanos , Masculino , Avaliação de Sintomas , Adulto JovemRESUMO
BACKGROUND: The aim of this study was to analyze the constituents of total and types I and III collagen fibers in the transversalis fascias of patients with indirect inguinal hernias, compared with samples removed from nonherniated cadavers. METHODS: Biopsy samples from 26 patients and 26 cadavers were analyzed. Hematoxylin-eosin and picrosirius staining techniques were used. The images obtained were analyzed using a video morphometric technique to determine the constituents of total collagen and types I and III collagen in the transversalis fascia. The picrosirius-stained tissues were submitted to observation under polarized-light microscopy. RESULTS: The results showed 17.3% less total collagen in patients with hernias compared with the control group (P < .01). Type I collagen in patients with indirect inguinal hernias was 23.7% less than the control group (P < .01), type III collagen was 6.4% less in the controls (P < .01). CONCLUSION: The lower percentages of total collagen and type I collagen in the transversalis fascias of patients with indirect inguinal hernias could be a factor in hernia formation.
Assuntos
Colágeno/análise , Fáscia/química , Hérnia Inguinal/patologia , Adulto , Fáscia/patologia , Hérnia Inguinal/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Adulto JovemAssuntos
Hérnia Inguinal/diagnóstico por imagem , Hérnia Inguinal/etiologia , Transplante de Rim/efeitos adversos , Transplante de Rim/diagnóstico por imagem , Obstrução Ureteral/diagnóstico por imagem , Obstrução Ureteral/etiologia , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , UltrassonografiaRESUMO
BACKGROUND: Inguinal hernia is the second most common surgical case in our field. The anatomical factors alone are not enough to explain the inguinal hernia. Studies show changes in the proportion and quantity of collagen fibers in the developing of inguinal hernia. The greater production of collagen type III compared to the type I could justify the thinning of the fascia transversalis and its weakness. AIM: To determine the quantitative and qualitative changes of collagen in the fascia transversalis in inguinal hernia patients and compare them to findings from corpses without inguinal hernia. METHOD: Prospective case-control study based on the biopsy of fascia transversalis of 27 patients and 24 corpses. The technique used was hematoxylin-eosin and picrosirius colorimetry. RESULTS: The medium percent area of collagen (types I + III) and collagen type I, in both groups, show no statistic difference. The quantity of collagen type III was greater in the patients. Patients classified with Nyhus IIIa presented greater quantity of collagen type III. CONCLUSION: There is no significant difference in the quantity of collagen in the fascia transversalis of patients compared to the controls. An increase in the quantity of collagen type III was found in patients with inguinal hernia and a greater quantity in those patients classified with Nyhus IIIa.
Assuntos
Colágeno/análise , Fáscia/química , Hérnia Inguinal/etiologia , Adulto , Idoso , Estudos de Casos e Controles , Fáscia/patologia , Hérnia Inguinal/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos ProspectivosRESUMO
BACKGROUND: Inguinal hernia is the second most common surgical case in our field. The anatomical factors alone are not enough to explain the inguinal hernia. Studies show changes in the proportion and quantity of collagen fibers in the developing of inguinal hernia. The greater production of collagen type III compared to the type I could justify the thinning of the fascia transversalis and its weakness. AIM: To determine the quantitative and qualitative changes of collagen in the fascia transversalis in inguinal hernia patients and compare them to findings from corpses without inguinal hernia. METHOD: Prospective case-control study based on the biopsy of fascia transversalis of 27 patients and 24 corpses. The technique used was hematoxylin-eosin and picrosirius colorimetry. RESULTS: The medium percent area of collagen (types I + III) and collagen type I, in both groups, show no statistic difference. The quantity of collagen type III was greater in the patients. Patients classified with Nyhus IIIa presented greater quantity of collagen type III. CONCLUSION: There is no significant difference in the quantity of collagen in the fascia transversalis of patients compared to the controls. An increase in the quantity of collagen type III was found in patients with inguinal hernia and a greater quantity in those patients classified with Nyhus IIIa.
RACIONAL: A hérnia inguinal é a segunda afecção cirúrgica mais comum em nosso meio. Os fatores anatômicos, isoladamente, não são suficientes para explicar a ocorrência das hérnias inguinais. Estudos apontam alterações na proporção e quantidade de fibras colágenas no desenvolvimento da hérnia inguinal. A maior produção de colágeno tipo III em relação ao tipo I poderia justificar o adelgaçamento da fascia transversalis e sua fraqueza. OBJETIVO: Determinar as alterações quantitativas e qualitativas de colágeno na fascia transversalis de doentes com hérnia inguinal e compará-las com achados em cadáveres sem hérnia inguinal. MÉTODOS: Estudo prospectivo caso-controle com análise de biopsia de fascia transversalis de 27 doentes e 24 cadáveres. Utilizou-se a técnica de coloração de hematoxilina-eosina e picrosirius. RESULTADOS: A área percentual média de colágeno (tipo I + tipo III) e colágeno tipo I, nos dois grupos, não apresentou diferença estatística. A quantidade de colágeno tipo III foi maior nos doentes. Doentes classificados com Nyhus IIIa apresentaram maior quantidade de colágeno tipo III. CONCLUSÃO: Não há diferença significativa na quantidade de colágeno em fascia transversalis de doentes comparados com controles. Foi encontrado aumento na quantidade de colágeno tipo III nos doentes com hérnia e em maior quantidade nos doentes classificados como Nyhus IIIa.