RESUMO

Paradoxical reactions have never been described in patients with paracoccidioidomycosis or other deep endemic mycoses out of the context of human immunodeficiency virus infection. We describe 2 patients with an acute form of paracoccidioidomycosis who presented with a worsening of their clinical manifestations while on appropriate antifungal treatment. These manifestations were severe and required adjunct corticosteroid therapy.

Assuntos

Corticosteroides/uso terapêutico , Antifúngicos/efeitos adversos , Antifúngicos/uso terapêutico , Fatores Imunológicos/uso terapêutico , Granulomatose Linfomatoide/induzido quimicamente , Paracoccidioidomicose/complicações , Paracoccidioidomicose/tratamento farmacológico , Adolescente , Criança , Histocitoquímica , Humanos , Imuno-Histoquímica , Linfonodos/patologia , Granulomatose Linfomatoide/patologia , Masculino , Microscopia , Pescoço/patologia , Pele/patologia