RESUMO
An experiment was carried out to evaluate the effect of an herbal choline feed plant additive on the productive parameters and blood metabolites of finishing lambs. Forty male Hampshire × Suffolk lambs (initial body weight of 30.36±3.75 kg) were assigned according to a completely randomized design. Treatments consisted of dietary inclusion of the herbal additive BioCholine at 0, 3, 6, and 9 g/kg dry matter for 56 days. A linear response for herbal choline dose was observed for daily gain, final body weight, feed conversion, blood glucose, and blood phosphatidylcholine as herbal choline level was increased in the diet. Total protein, globulins, and low-density lipoproteins showed a quadratic effect, and there were no effects on intake, Longissimus dorsi area, back fat, blood cholesterol, triglycerides, high-density lipoproteins, or albumins. The inclusion of the herbal choline feed plant additive improved daily gain and feed efficiency of finishing lambs. The choline feed plant additive is a source that can be used to meet choline requirements in small ruminants, as demonstrated by blood phosphatidylcholine and lamb performance.(AU)
Assuntos
Animais , Masculino , Ovinos/fisiologia , Aditivos Alimentares/efeitos adversos , Ração Animal/análise , Fitoterapia/métodos , Fosfatidilcolinas/efeitos adversos , Fosfolipídeos/efeitos adversosRESUMO
BACKGROUND: The lower third of the face and neck have distinct changes that occur with aging: the lost of the perfect jaw line due to laxicity of skin and fat deposits associated with "turkey neck." Theses changes can be globally and drastically addressed with traditional rhytidectomy, however patients increasingly seek less invasive procedures. Injections with Lipostabil Endovena-a mixture of phosphatidylcholine and deoxycholate, a bile salt-have been used to reduce unwanted, accumulated fat. Recent in vivo investigations indicate that phosphatidylcholine and deoxycholate cause adipocyte lysis, an inflammatory processes and fibrosis. These reactions lead to skin retraction. OBJECTIVE: This paper reports the author's experience treating aging neck using Lipostabil Endovena. RESULTS: Laxity of the skin improved in all patients. A marked reduction in double chins was noted and the jaw line was reconstructed. Adverse effects, including transient burning, erythema and local swelling were present in all patients, but resolved themselves without intervention. CONCLUSION: The author's clinical experience supports the conclusion that Lipostabil Endovena treats subcutaneous fat tissue and that fibrosis after the inflammatory process retracts the skin, tightening the injected area and improving the aging neck.
Assuntos
Técnicas Cosméticas , Fosfatidilcolinas/administração & dosagem , Envelhecimento da Pele/efeitos dos fármacos , Gordura Subcutânea/efeitos dos fármacos , Adulto , Queixo , Técnicas Cosméticas/efeitos adversos , Feminino , Seguimentos , Humanos , Arcada Osseodentária , Masculino , Pessoa de Meia-Idade , Pescoço , Fosfatidilcolinas/efeitos adversos , Rejuvenescimento , Resultado do TratamentoRESUMO
Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases. Recently, it has also been used in the treatment of localized fat deposits. We report on the authors' clinical experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat deposits, showing the clinical response and side-effects. Volunteers received phosphatidylcholine injections in several areas of localized fat deposits, with a minimum interval of one week and mean interval of 15 days between applications. Laboratory tests were performed during the period of the drug use. Clinical results reflect that phosphatidylcholine was efficacious in reducing the fatty pads in the treated areas, with few side effects. From the authors' point of view, the off-label use of phosphatidylcholine in the treatment of fatty pads and small areas of localized fat is safe, low cost, and effective.