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Einstein (Sao Paulo) ; 13(2): 338-9, 2015.
Artigo em Inglês, Português | MEDLINE | ID: mdl-26154556

RESUMO

Clostridium difficile is the major etiological agent of pseudomembranous colitis and is found in up to 20% of adult inpatients. The recommended treatment is antibiotic therapy with metronidazole and/or vancomycin. However, the recurrence rate may reach up to 25% and it increases in each episode. The newest alternative to treat diarrhea due to recurrent Clostridium difficile is fecal microbiota transplantation. The procedure was performed in 12 patients, with a 6-month follow-up on 10 of them. Of the ten cases, bacterial recurrence was diagnosed in only one patient, after a course of antibiotic to treat urinary tract infection, without presenting with diarrhea. The particularity of our study, besides being an unprecedented event in South America, is the way to perform the infusion of fecal microbiota by enteroscopy.


Assuntos
Clostridioides difficile , Diarreia/terapia , Endoscópios Gastrointestinais/normas , Enterocolite Pseudomembranosa/terapia , Fezes/microbiologia , Microbiota , Idoso de 80 Anos ou mais , Diarreia/microbiologia , Enterocolite Pseudomembranosa/microbiologia , Humanos , Masculino , Recidiva , Transplante Homólogo/métodos , Resultado do Tratamento
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