Assuntos
COVID-19/diagnóstico , Doenças Labiais/diagnóstico , SARS-CoV-2/isolamento & purificação , Dermatopatias Vesiculobolhosas/diagnóstico , Trombose/diagnóstico , Biópsia , COVID-19/complicações , COVID-19/imunologia , COVID-19/virologia , Teste para COVID-19 , Dexametasona/uso terapêutico , Feminino , Humanos , Lábio/irrigação sanguínea , Lábio/imunologia , Lábio/patologia , Doenças Labiais/tratamento farmacológico , Doenças Labiais/imunologia , Doenças Labiais/patologia , Microvasos/patologia , Dermatopatias Vesiculobolhosas/tratamento farmacológico , Dermatopatias Vesiculobolhosas/imunologia , Dermatopatias Vesiculobolhosas/patologia , Glicoproteína da Espícula de Coronavírus/isolamento & purificação , Trombose/tratamento farmacológico , Trombose/imunologia , Trombose/patologia , Adulto JovemRESUMO
Objetivo: relatar um caso de paracoccidioidomicose (Pbmicose), diagnosticado pelo cirurgião-dentista, e o tratamento instituído a um morador de zona urbana. Relato de caso: paciente do sexo masculino, com 59 anos de idade, leucoderma, compareceu à clínica odontológica com lesão em boca há cerca de vinte dias e queixa de mobilidade dental na região anteroinferior. Durante a anamnese, constatou-se dificuldade respiratória, hipertensão controlada, tabagismo e etilismo crônico. No exame físico, foi observado aumento de volume do lábio inferior, linfadenopatia bilateral submandibular e lesões ulceradas com aspecto moriforme em mucosa bucal e gengiva inserida do elemento 31 ao 45. Foi realizada biópsia incisional na lesão com resultado positivo para Pbmicose. O paciente foi medicado com itraconazol e apresenta-se periodicamente para acompanhamento. Considerações finais: as lesões bucais dessa doença correspondem a úlceras crônicas e granulomatosas, semelhantes à lesão provocada pelo carcinoma epidermoide oral, assim, o cirurgião-dentista deve conhecer esta micose e considerá-la na elaboração do diagnóstico diferencial. (AU)
Objective: to report a case of paracoccidioidomycosis (Pbmycosis) diagnosed by the dentist, as well as the treatment applied to a resident of an urban area. Case report: male patient, 59 years old, white, referred to the dental clinic with a lesion in the mouth of around 20 days and complaint of tooth mobility in the anteroinferior region. The anamnesis showed respiratory distress, controlled hypertension, and chronic smoking and alcoholism. The physical examination showed increased volume of the lower lip, bilateral submandibular lymphadenopathy, moriform ulcerated lesions in the buccal mucosa, and gum insertion from tooth 31 to 45. An incisional biopsy was performed on the lesion with a positive result for Pbmycosis. The patient was treated with itraconazole and he shows up periodically for follow-up. Final considerations: the oral lesions of this disease correspond to chronic and granulomatous ulcers, similar to the lesion caused by the oral squamous cell carcinoma, thus, the dentist should understand this mycosis and consider it when producing the differential diagnosis. (AU)
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Paracoccidioidomicose/patologia , Doenças Labiais/patologia , Mucosa Bucal/patologia , Paracoccidioidomicose/tratamento farmacológico , Biópsia , Itraconazol/uso terapêutico , Antifúngicos/uso terapêuticoRESUMO
Juvenile xanthogranuloma is a rare non-Langerhans cell histiocytosis that usually occurs in the skin of children. Extracutaneous involvement is rare, and few cases affecting the oral cavity have been reported. The purpose of the present study was to report two cases of oral juvenile xanthogranuloma affecting the lower lip of a 14-year-old girl and the soft palate of a second 14-month-old girl, both present as yellowish papules. The lesions were surgically excised, and histological and immunohistochemical analysis showed a proliferation of non-Langerhans cells histiocytes and foamy cells, fulfilling the morphologic features of juvenile xanthogranuloma. The patients have been followed up, respectively, for 36 and 49 months with no signs of recurrence. Based on these results, juvenile xanthogranuloma should be included in the differential diagnosis of oral yellowish soft-tissue swellings in children and adolescents and should be managed through conservative surgical excision.
Assuntos
Doenças Labiais/patologia , Doenças da Boca/patologia , Palato Mole/patologia , Xantogranuloma Juvenil/patologia , Adolescente , Feminino , Humanos , Lactente , Doenças Labiais/cirurgia , Doenças da Boca/cirurgia , Palato Mole/cirurgia , Xantogranuloma Juvenil/cirurgiaRESUMO
The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability.
Assuntos
Neoplasias Labiais/patologia , Lábio/patologia , Adolescente , Adulto , Distribuição por Idade , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Biópsia , Brasil/epidemiologia , Criança , Pré-Escolar , Diagnóstico Bucal/métodos , Feminino , Humanos , Lactente , Doenças Labiais/epidemiologia , Doenças Labiais/patologia , Neoplasias Labiais/epidemiologia , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Estudos Retrospectivos , Sensibilidade e Especificidade , Distribuição por Sexo , Fatores Sexuais , Adulto JovemRESUMO
El síndrome de Laugier-Hunziker es un trastorno pigmentario adquirido poco frecuente, caracterizado por presentar lesiones hiperpigmentadas cutaneomucosas idiopáticas que pueden asociarse a melanoniquia longitudinal. A pesar de ser considerado una enfermedad benigna sin manifestaciones sistémicas ni potencial maligno, es clave realizar el diagnóstico diferencial con otros trastornos pigmentarios, en especial con el síndrome de Peutz-Jeghers. Se presenta aquí el caso de un paciente con este síndrome poco frecuente. (AU)
Laugier-Hunziker syndrome is a rare acquired pigmentary disorder that is characterized by idiopathic mucocutaneous pigmentation that may be associated with longitudinal melanonychia. Although this syndrome is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders, especially Peutz-Jeghers syndrome. We report the case of a patient with this unusual syndrome. (AU)
Assuntos
Humanos , Masculino , Idoso , Hiperpigmentação/diagnóstico , Doenças Labiais/diagnóstico , Dermatopatias/diagnóstico , Dermatopatias/patologia , Síndrome de Peutz-Jeghers/diagnóstico , Hiperpigmentação/patologia , Diagnóstico Diferencial , Doenças Labiais/patologia , Doenças da Boca/diagnóstico , Doenças da Boca/patologiaRESUMO
Abstract: The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability.
Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Adulto Jovem , Neoplasias Labiais/patologia , Lábio/patologia , Biópsia , Brasil/epidemiologia , Neoplasias Labiais/epidemiologia , Fatores Sexuais , Reprodutibilidade dos Testes , Estudos Retrospectivos , Sensibilidade e Especificidade , Fatores Etários , Distribuição por Sexo , Distribuição por Idade , Diagnóstico Bucal/métodos , Doenças Labiais/patologia , Doenças Labiais/epidemiologia , Pessoa de Meia-IdadeRESUMO
BACKGROUND: The oral mucosa in patients with epidermolysis bullosa (EB) can be affected with different lesions and degrees of severity. However, patterns of oral lesions in distinct types of EB are still unclear. OBJECTIVES: The purpose of this study was to determine the frequency and distribution of four types of lesions (erythema, erosion, atrophy, and blister) for each oral site and to calculate the interobserver reliability for each type of lesion in each site. METHODS: Ninety-two patients with different EB types were assessed independently by an oral medicine specialist and a dermatologist. The degree of agreement was calculated by the intraclass correlation coefficient (ICC). RESULTS: The most affected oral site was the tongue, with the most frequent lesion being erythema and atrophy [54(58.7%) patients] for the oral medicine specialist and erosion [54(58.7%) patients] for the dermatologist. Patients with recessive dystrophic EB-severe generalized (RDEB-sev gen) showed the highest mean of sites involved by each lesion for both oral medicine and dermatology. The interobserver reliability on the total of lesions was excellent on only 3 sites: lower lip (ICC: 0.89; 95%CI:0.83-0.92), hard palate (ICC:0.85; 95%CI:0.72-0.91), and tongue (ICC:0.89; 95%CI:0.84-0.92), whereas the interobserver reliability calculated for each single oral lesion showed a lower agreement. CONCLUSION: Total distribution of sites involved by four types of lesions was higher in RDEB-sev gen than in the rest of EB types, with a predominance of erythema followed by erosion. The agreement on the type of lesion was found to be poor-moderate for many oral sites.
Assuntos
Epidermólise Bolhosa/patologia , Doenças da Boca/patologia , Mucosa Bucal/patologia , Adolescente , Adulto , Atrofia , Vesícula/patologia , Criança , Pré-Escolar , Dermatologia , Epidermólise Bolhosa Distrófica/patologia , Eritema/patologia , Feminino , Humanos , Lactente , Doenças Labiais/patologia , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Medicina Bucal , Palato/patologia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Doenças da Língua/patologia , Adulto JovemRESUMO
Phyma is the last stage of rosacea and is due to chronic inflammation and edema. It can affect nose (rhinophyma), chin (gnatophyma), forehead (metophyma), ears (otophyma) and eyelids (blepharophyma). Rhinophyma is the most frequent location and there are few reports about gnatophyma. We report the case of a female patient, 41 years old, who had an infiltrated, erythematous, edematous plaque around the chin and lower lip for two years. Histopathology showed perivascular lymphocytic infiltrate, hypertrophied follicles and sebaceous glands, dilated vessels and fibrosis. She was treated with oral tetracycline, oral ivermectin and metronidazole cream with a satisfactory response. The clinical, histopathological and therapeutic response correlation confirmed the diagnosis of gnatophyma, a rare variant of phyma.
Assuntos
Dermatoses Faciais/patologia , Doenças Labiais/patologia , Rosácea/patologia , Adulto , Queixo , Feminino , HumanosRESUMO
Phyma is the last stage of rosacea and is due to chronic inflammation and edema. It can affect nose (rhinophyma), chin (gnatophyma), forehead (metophyma), ears (otophyma) and eyelids (blepharophyma). Rhinophyma is the most frequent location and there are few reports about gnatophyma. We report the case of a female patient, 41 years old, who had an infiltrated, erythematous, edematous plaque around the chin and lower lip for two years. Histopathology showed perivascular lymphocytic infiltrate, hypertrophied follicles and sebaceous glands, dilated vessels and fibrosis. She was treated with oral tetracycline, oral ivermectin and metronidazole cream with a satisfactory response. The clinical, histopathological and therapeutic response correlation confirmed the diagnosis of gnatophyma, a rare variant of phyma.
Fima é o estágio final da rosácea e ocorre devido ao edema e inflamação crônica. Pode acometer nariz (rinofima), mento (gnatofima), fronte (metofima), orelhas (otofima) e pálpebras (blefarofima). Rinofima é a localização mais encontrada e há raros relatos de gnatofima. Relataremos paciente feminina, 41 anos, que apresentava placa infiltrada, eritêmato-edematosa, em todo o mento e lábio inferior há dois anos. Histopatológico com infiltrado linfocitário perianexial e perivascular, folículos e glândulas sebáceas hipertrofiadas, vasos ectasiados e fibrose perianexial. Foi instituído tratamento com tetraciclina via oral, ivermectina via oral e metronidazol creme com resposta satisfatória. Através da correlação clínica, histopatológica e resposta terapêutica confirmou-se o diagnóstico da variante rara de fima, gnatofima.
Assuntos
Adulto , Feminino , Humanos , Dermatoses Faciais/patologia , Doenças Labiais/patologia , Rosácea/patologia , QueixoAssuntos
Adulto , Feminino , Humanos , Gravidez , Doenças da Boca/microbiologia , Úlceras Orais/microbiologia , Paracoccidioidomicose/patologia , Complicações Infecciosas na Gravidez/microbiologia , Doenças Labiais/microbiologia , Doenças Labiais/patologia , Doenças da Boca/patologia , Úlceras Orais/patologia , Complicações Infecciosas na Gravidez/patologiaAssuntos
Doenças da Boca/microbiologia , Úlceras Orais/microbiologia , Paracoccidioidomicose/patologia , Complicações Infecciosas na Gravidez/microbiologia , Adulto , Feminino , Humanos , Doenças Labiais/microbiologia , Doenças Labiais/patologia , Doenças da Boca/patologia , Úlceras Orais/patologia , Gravidez , Complicações Infecciosas na Gravidez/patologiaRESUMO
Orf virus is the etiological agent of contagious ecthyma, a severe exanthematic disease that affects small ruminants. Orf virus is zoonosis that is associated with occupational contact with infected animals in human disease. Clinically, contagious ecthyma is characterized by the appearance of vesicles, pustules, ulcers, and papillomatous proliferative lesions on the skin of the lips and nostrils. Here we describe a case of lethal cutaneous multifocal Orf virus infection in goats in the Amazon region of Brazil. Exanthematic lesions were collected and epidemiological and clinical data were obtained. Orf virus was detected using PCR amplification of the whole B2L, VIR, and VEGF open reading frame. Phylogenetic analysis revealed that this virus clustered together with the Orf virus samples isolated during classical contagious ecthyma. The present work is the first to report a severe proliferative Orf virus case in South America.
Assuntos
Doenças das Cabras/epidemiologia , Cabras/virologia , Vírus do Orf/isolamento & purificação , Vírus do Orf/patogenicidade , Dermatopatias Infecciosas/veterinária , Sequência de Aminoácidos , Animais , Brasil/epidemiologia , Ectima Contagioso/epidemiologia , Ectima Contagioso/patologia , Ectima Contagioso/virologia , Genes Virais , Doenças das Cabras/patologia , Doenças das Cabras/virologia , Doenças Labiais/epidemiologia , Doenças Labiais/patologia , Doenças Labiais/veterinária , Doenças Labiais/virologia , Dados de Sequência Molecular , Vírus do Orf/classificação , Vírus do Orf/genética , Filogenia , Alinhamento de Sequência , Dermatopatias Infecciosas/epidemiologia , Dermatopatias Infecciosas/virologiaRESUMO
BACKGROUND: Amyloidosis is associated with or caused by amyloid deposition. These fibrillar proteins may be deposited extracellularly causing tissue damage or impairment. OBJECTIVES: The aim of the study was to retrospectively review pathology archives in two oral diagnostic centers for cases fulfilling criteria of amyloidosis and to differentiate AA and AL types of amyloidosis. METHODS: The clinicopathological features, alkaline Congo red staining, with and without pretreatment with potassium permanganate, and immunohistochemical (IHC) staining with anti-AA, anti-kappa (κ), and anti-lambda (λ) light chain antibodies were carried out and analyzed. RESULTS: The search identified 14 cases. Ten patients were women and four were men, with a mean age of 58 years. Eleven patients had systemic involvement by amyloidosis (associated either with multiple myeloma or plasma cell dyscrasia/monoclonal gammopathies), while three presented the localized type, one of them associated with plasmacytoma. All cases showed positivity for κ or λ light chains (AL-amyloid) and presented resistance to the potassium permanganate pretreatment. CONCLUSIONS: Our results show that the head and neck region is preferentially affected by systemic AL-amyloidosis, usually associated with plasma cell dyscrasia. Interestingly, two cases affected by inflammatory rheumatic diseases presented AL-amyloid deposition. Moreover, even after pretreatment with potassium permanganate, which was helpful in highlighting the presence of AL-amyloid, in agreement with the IHC findings, clinical classifications should be carefully made in systemic amyloidosis.
Assuntos
Amiloidose/patologia , Doenças da Boca/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Amiloide/análise , Amiloidose/complicações , Corantes , Vermelho Congo , Face , Feminino , Seguimentos , Humanos , Cadeias kappa de Imunoglobulina/análise , Cadeias lambda de Imunoglobulina/análise , Indicadores e Reagentes , Doenças Labiais/patologia , Masculino , Pessoa de Meia-Idade , Gamopatia Monoclonal de Significância Indeterminada/complicações , Mieloma Múltiplo/complicações , Pescoço/patologia , Palato/patologia , Paraproteinemias/complicações , Permanganato de Potássio , Estudos Retrospectivos , Proteína Amiloide A Sérica/análise , Doenças da Língua/patologiaRESUMO
OBJECTIVE: To evaluate the clinicopathologic features of pediatric mucoceles diagnosed in two public institutions in Brazil during an 18-year period. METHOD AND MATERIALS: Clinical data (age, sex, history of trauma, location, and size) of 138 cases of mucoceles in children 0 to 16 years of age were obtained from medical records. The lesions were classified as mucus extravasation phenomenon and mucus retention phenomenon, depending on the presence of epithelial lining in the microscopic analysis. RESULTS: Mucoceles made up 24.5% of the oral pediatric lesions diagnosed in the period of study. Age at diagnosis ranged from 0.4 to 16.0 years, with a mean age of 10.8 years. Of the total of mucoceles, 87 were observed in females and 51 in males. The lower lip was the most commonly affected site, and a history of trauma was related by 87% of the patients. Histologically, 96.4% of mucoceles were diagnosed as mucus extravasation phenomenon. Cases of mucus retention phenomenon were relatively more common in the floor of the mouth, since one in three lesions in this location belonged to this histologic type. Regarding lesions in the lower lip, only 2.65% were diagnosed as mucus retention phenomenon. CONCLUSION: Trauma is the main etiologic factor involved in the development of mucoceles in children. The mucus extravasation phenomenon is the most common histologic type in this age group. Although rare, the retention type seems to be more common in lesions on the floor of the mouth.
Assuntos
Mucocele/patologia , Doenças das Glândulas Salivares/patologia , Adolescente , Criança , Pré-Escolar , Traumatismos Faciais/complicações , Feminino , Humanos , Lactente , Doenças Labiais/patologia , Masculino , Soalho Bucal/patologia , Mucocele/etiologia , Estudos Retrospectivos , Glândulas Salivares Menores/patologiaRESUMO
Antimalarial drugs, like chloroquine, may produce hyperpigmentation of the oral mucosa, affecting most commonly the palate. Its pathogenesis is not clear; an increased production of melanin is currently believed to be the cause of this oral manifestation. The purpose of this study was to report a case of atypical oral mucosal hyperpigmentation secondary to antimalarial therapy. A 66-year-old, dark skinned woman was evaluated for oral pigmentation. The patient had a history of chloroquine therapy, and presented a diffuse blue-gray pigmentation in the hard palate and, mainly, in the lower lip. Diagnostic hypothesis were of physiologic pigmentation, drug-induced pigmentation, pigmentation associated with systemic diseases, smoker's melanosis and post-inflammatory pigmentation. Incisional biopsy was conducted and histopathological examination revealed lichenoid dermatitis and pigment incontinence. Fontana-Masson staining was positive for melanin, but Perl's iron staining was negative. The histopathological diagnosis was consistent with melanin incontinence related to drug-induced lichenoid reaction secondary to chloroquine therapy. Adequate correlation of clinical and microscopic aspects was essential for the definitive diagnosis, especially in atypical cases. This diagnosis is of great relevance for the patient, since the oral manifestation might be an early sign of ocular complications due to antimalarial therapy. Therefore, the identification of these oral manifestations indicates regular evaluations by an ophtalmologist, preventing greater complications of antimalarial therapy for the patient.
Assuntos
Antimaláricos/efeitos adversos , Cloroquina/efeitos adversos , Erupções Liquenoides/induzido quimicamente , Doenças Labiais/induzido quimicamente , Idoso , Feminino , Humanos , Erupções Liquenoides/patologia , Doenças Labiais/patologiaRESUMO
Jorge Lobo's Disease (JLD) is a chronic granulomatous cutaneous mycosis caused by Lacazia loboi. The most typical lesions are keloid-like growths preferentially located on limbs and ears. To the best of the authors' knowledge, only one labial case has previously been reported. We describe the case of a man who presented with a left-sided papulonodular lesion of 10 years' duration on the vermillion border of the upper lip. A successful surgical resection of the lesion was performed and there was no recurrence in eight years of follow-up.
Assuntos
Doenças Labiais/microbiologia , Lobomicose/patologia , Seguimentos , Humanos , Doenças Labiais/patologia , Doenças Labiais/cirurgia , Lobomicose/cirurgia , Masculino , Pessoa de Meia-IdadeRESUMO
Doença de Jorge Lobo (DJL) é infecção granulomatosa cutânea crônica produzida pelo fungo Lacazia loboi, cujas lesões mais típicas têm aspecto queloidiano, com localizações preferenciais em membros e orelhas. As lesões restringem-se à pele, havendo apenas uma referência, do conhecimento dos autores, à localização em semimucosa labial. Apresenta-se caso de doença de Jorge Lobo em paciente masculino, com lesão papulonodular no vermelhão do lábio superior, à esquerda, de dez anos de evolução, exitosamente submetida a tratamento cirúrgico, sem recidiva após oito anos.
Jorge Lobo's Disease (JLD) is a chronic granulomatous cutaneous mycosis caused by Lacazia loboi. The most typical lesions are keloid-like growths preferentially located on limbs and ears. To the best of the authors' knowledge, only one labial case has previously been reported. We describe the case of a man who presented with a left-sided papulonodular lesion of 10 years' duration on the vermillion border of the upper lip. A successful surgical resection of the lesion was performed and there was no recurrence in eight years of follow-up.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Doenças Labiais/microbiologia , Lobomicose/patologia , Seguimentos , Doenças Labiais/patologia , Doenças Labiais/cirurgia , Lobomicose/cirurgiaRESUMO
O mucocele é uma lesão comum da mucosa bucal, que resulta da ruptura de um ducto deotglândula salivar e consequente derramamento de mucina para o interior dos tecidos moles circunjacentes. Pode surgir em vários sítios da cavidade bucal sendo o lábio inferior região mais prevalente, contabilizando mais de 80% dos casos. Como forma de tratamento, pode ser realizada a exérese local, com a enucleação e remoção da glândula salivar, e ou tratada por eletrocirurgia, criocirurgia ou pela vaporização com laser de C02. O objetivo deste trabalho é apresentar uma revisão de literatura a respeito do mucocele, bem como um relato de caso clinico e a opção de tratamento escolhida.
The mucocele is a common injury of the oral mucosa, resulting from a ruptured salivarygland duct and consequent spillage of mucin into the interior of the surrounding soft tissues. Can arise in various sites of the oral cavity and the lower lip area was the most prevalent, accounting for more than 80% of cases. As a form of treatment can be performed local excision with enucleation and remova I of the salivary gland, and I or treated by electrosurgery, cryosurgery or laser vaporization of C02. The aim of this paper is to present a review of the literature regarding the mucocele and one case report and treatment option chosen.
Assuntos
Humanos , Masculino , Adulto Jovem , Doenças Labiais/patologia , Glândulas Salivares/anatomia & histologia , Mucocele/patologiaRESUMO
Hamartoma is a proliferation of normal tissues that are considered endogenous to the site of occurrence. In the head and neck region, hamartomas composed of other tissues different from blood and lymphatic vessels (hemangiomas and lymphangiomas) are very uncommon. We report an unusual case of upper lip angiomyolipomatous hamartoma in an 8-month-old patient. The patient underwent surgical treatment and the 1-year follow-up revealed no signs of recurrence. Angiomyolipomatous hamartoma is a very rare condition in the paediatric population group, especially in the head and neck region. It should be considered in the differential diagnosis of congenital lesions in childhood.
Assuntos
Angiomiolipoma/patologia , Hamartoma/patologia , Doenças Labiais/patologia , Neoplasias Labiais/patologia , Angiomiolipoma/cirurgia , Diagnóstico Diferencial , Hamartoma/cirurgia , Humanos , Lactente , Doenças Labiais/cirurgia , Neoplasias Labiais/cirurgia , Masculino , Resultado do TratamentoRESUMO
BACKGROUND: Actinic cheilitis (AC) is a premalignant condition intimately related to exposure of the lips to sun rays. AIM: The objective of this study was to evaluate the elastic and collagen fibers in the lamina propria of AC. The degree of epithelial atypia was correlated with the quantity of elastic and collagen fibers. MATERIALS AND METHODS: Fifty-one cases were investigated. One slide was stained with hematoxylin-eosin for the evaluation of atypia, the second was stained with Weigert's resorcin-fuchsin for the assessment of elastic fibers, and the third slide was stained with Mallory's trichrome for the analysis of collagen fibers. RESULTS: Ordinal logistic regression analysis revealed a significant correlation between the presence of atypia and collagen fibers (P<0.05). CONCLUSIONS: It was concluded that there seems to be a reduction in the quantity of collagen fibers in cases of moderate and severe atypia. No correlation was observed between the degradation of elastic system fibers and the grade of dysplasia.