RESUMO
Abstract The penile localization of pigmented Bowen's disease has been rarely reported and has been mostly related to human papillomavirus infection. Early diagnosis and treatment are important to prevent progression to invasive squamous cell carcinoma. However, diagnosis can be challenging because it may be difficult to distinguish from melanoma, even using dermoscopy. Reflectance confocal microscopy may be useful in suggesting the bedside diagnosis before the histopathological confirmation. A case of penile pigmented Bowen's disease is described along with its dermoscopy and reflectance confocal microscopy findings and their correlation with histopathology.
Assuntos
Humanos , Neoplasias Cutâneas/diagnóstico por imagem , Doença de Bowen/diagnóstico por imagem , Microscopia Confocal , Dermoscopia , Diagnóstico DiferencialRESUMO
The penile localization of pigmented Bowen's disease has been rarely reported and has been mostly related to human papillomavirus infection. Early diagnosis and treatment are important to prevent progression to invasive squamous cell carcinoma. However, diagnosis can be challenging because it may be difficult to distinguish from melanoma, even using dermoscopy. Reflectance confocal microscopy may be useful in suggesting the bedside diagnosis before the histopathological confirmation. A case of penile pigmented Bowen's disease is described along with its dermoscopy and reflectance confocal microscopy findings and their correlation with histopathology.
Assuntos
Doença de Bowen , Neoplasias Cutâneas , Doença de Bowen/diagnóstico por imagem , Dermoscopia , Diagnóstico Diferencial , Humanos , Microscopia Confocal , Neoplasias Cutâneas/diagnóstico por imagemRESUMO
Abstract Porokeratosis is a disorder of epidermal keratinization characterized by the presence of annular hyperkeratotic plaques. Its etiopathogenesis is not yet fully understood, but a relationship with immunosuppression has been reported. Dermoscopic examination revealed a classic yellowish-white ring-like structure that resembled “volcanic crater contour” – the so-called cornoid lamella. We describe a case of porokeratosis in a female patient with chronic lymphedema, which was similar to Bowen’s disease due to the many glomerular vessels seen on clinical examination and dermoscopy.
Assuntos
Humanos , Feminino , Idoso , Doença de Bowen/patologia , Doença de Bowen/diagnóstico por imagem , Poroceratose/patologia , Poroceratose/diagnóstico por imagem , Dermoscopia/métodos , Doença Crônica , Diagnóstico Diferencial , Eritema/patologia , Eritema/diagnóstico por imagem , Linfedema/patologia , Linfedema/diagnóstico por imagemRESUMO
Porokeratosis is a disorder of epidermal keratinization characterized by the presence of annular hyperkeratotic plaques. Its etiopathogenesis is not yet fully understood, but a relationship with immunosuppression has been reported. Dermoscopic examination revealed a classic yellowish-white ring-like structure that resembled "volcanic crater contour" - the so-called cornoid lamella. We describe a case of porokeratosis in a female patient with chronic lymphedema, which was similar to Bowen's disease due to the many glomerular vessels seen on clinical examination and dermoscopy.
Assuntos
Doença de Bowen/diagnóstico por imagem , Doença de Bowen/patologia , Dermoscopia/métodos , Poroceratose/diagnóstico por imagem , Poroceratose/patologia , Idoso , Doença Crônica , Diagnóstico Diferencial , Eritema/diagnóstico por imagem , Eritema/patologia , Feminino , Humanos , Linfedema/diagnóstico por imagem , Linfedema/patologiaRESUMO
BACKGROUND: The ultrasound biomicroscopy (UBM) technique generates high-resolution echographic images using acoustic frequencies between 20 and 200 MHz. In dermatology, it enables non-invasive visualization of cutaneous structures. In this sense, several studies are being conducted for the measurement of cutaneous tumor sizes and for the evaluation of their response to therapeutic procedures. The present work was conducted to analyze the ability of UBM to identify diverse histological structures associated with cutaneous carcinomas ex vivo regarding the evaluation of the technique as a diagnostic tool that could, eventually, improve the patient's healthcare protocol. METHODS: Ex vivo human tissue samples, corresponding to basal cell carcinoma and squamous cell carcinoma cases, were studied. The ultrasonic system operated with a center frequency of 45MHz and the histological structures were identified by comparison with the light microscopy images. RESULTS: The histological components present in the tumors were identified by variations in the echogenicity level for several of the studied cases and particular characteristics were observed for the different tumor types. CONCLUSION: The possibility of differentiating the histological components associated with cutaneous carcinomas indicates the potential use of UBM for diagnostic applications. However, a larger number of specimens must be studied.