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1.
Wilderness Environ Med ; 22(1): 7-14, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21377113

RESUMO

OBJECTIVE: The Lake Louise AMS Self-Report Score (LLSelf) is a commonly used, validated assessment of acute mountain sickness (AMS). We compared LLSelf and visual analog scales (VAS) to quantify AMS on Aconcagua (6962 m). METHODS: Prospective observational cohort study at Plaza de Mulas base camp (4365 m), Aconcagua Provincial Park, Argentina. Volunteers climbing in January 2009 were enrolled at base camp and ascended at their own pace. They completed the LLSelf, an overall VAS [VAS(o)], and 5 individual VAS [VAS(i)] corresponding to the items of the LLSelf when symptoms were maximal. Composite VAS [VAS(c)] was calculated as the sum of the 5 VAS(i). RESULTS: A total of 127 volunteers consented to the study. Response rate was 52.0%. AMS occurred in 77.3% of volunteers, while 48.5% developed severe AMS. Median (interquartile range, IQR) LLSelf was 4 (3-7). Median (IQR) VAS(o) was 36 mm (23-59). VAS(o) was linear and correlated with LLSelf: slope = 6.7 (95% CI: 4.4-9.0), intercept = 3.0 (95% CI: -10.0-16.1), ρ = 0.71, τ = 0.55, R(2) = 0.45, p < 0.001. Median (IQR) VAS(c) was 29 (13-44). VAS(c) was also linear and correlated with LLSelf: slope = 5.9 (95% CI: 4.9-6.9), intercept = -0.6 (95% CI: -6.3-5.1), ρ = 0.83, τ = 0.68, R(2) = 0.73, p < 0.001. The relationship between the 5 VAS(i) and LLSelf(i) was less significant and less linear than that between VAS(o), VAS(c), and LLSelf. CONCLUSIONS: While both VAS(o) and VAS(c) for assessment of AMS appear to be linear with respect to LLSelf, the amount of scatter within the VAS is considerable. The LLSelf remains the gold standard for the diagnosis of AMS.


Assuntos
Doença da Altitude/diagnóstico , Montanhismo , Doença Aguda , Adulto , Doença da Altitude/classificação , Argentina , Estudos de Coortes , Feminino , Humanos , Masculino , Medição da Dor , Estudos Prospectivos , Reprodutibilidade dos Testes , Autoavaliação (Psicologia) , Índice de Gravidade de Doença
2.
Expert Rev Neurother ; 7(3): 245-8, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17341172

RESUMO

A human being's exposure to altitude, and the consequent hypobarism, entails a complex series of adaptive mechanisms that depend on the rate of ascent and the altitude reached. When these mechanisms fail, so-called acute mountain sickness (AMS) results, with headache as its predominant symptom. It has been observed, nonetheless, that well-acclimated mountaineers may have headache without symptoms of AMS. We consider that high altitude and ensuing hypobarism bring about three possibilities of cephalalgia: the first is covered by the set of AMS clinical manifestations and is undoubtedly the most frequent; the second occurs independently of acute mountain sickness and is probably due exclusively to hypoxia; and the third includes altitude-triggered migraine or migraine-like episodes. These are neurogenic problems secondary to hypoxia caused by hypobarism and, in all events, have a common denominator: hypoxia and a fundamental white organ, the brain.


Assuntos
Doença da Altitude/diagnóstico , Doença da Altitude/fisiopatologia , Encéfalo/fisiopatologia , Transtornos da Cefaleia Secundários/diagnóstico , Transtornos da Cefaleia Secundários/fisiopatologia , Hipóxia Encefálica/diagnóstico , Hipóxia Encefálica/fisiopatologia , Doença da Altitude/classificação , Doença da Altitude/complicações , Transtornos da Cefaleia Secundários/classificação , Humanos , Hipóxia Encefálica/classificação , Hipóxia Encefálica/complicações
8.
Ginecol. & obstet ; 37(11): 43-50, 1991. tab, ilus
Artigo em Espanhol | LILACS, LIPECS | ID: lil-107151

RESUMO

Para el estudio de edad de menarquia y edad de menopausia en las grandes alturas de los Andes, se han estudiado 11 mujeres cuyo rango de edad fué de 38 a 62 años, de las cuales 49 mujeres habitan en las grandes alturas y 62 del nivel del mar como control. La edad de menarquia en la altura fué de 14.6 +/- 0.2 años, la edad de la menopausia de 45.3 +/- 0.7 años y el período reproductivo de 30.7 +/- 0.9 años; mientras que, a nivel del mar la edad de menarquia fué de 12.6 +/- 0.2 años, la edad de menopausia 48.2 +/- 0.7 años y el período reproductivo 35.4 +/- 0.9 años. En las grandes alturas hay un retraso en la edad de menarquia de 2.0 años, en la edad de menopausia en las grandes alturas hay un adelanto de 2.9 años y en el promedio de edad reproductiva en las grandes alturas hay un acortamiento de 4.8 años; sin embargo, la capacidad reproductiva en la altura no ha tenido ninguna alteración. La tasa de gestación en las grandes alturas fué 7.3 +/- 0.5 y a nivel del mar 2.8 +/- 0.4, lo que indica que la hipoxia de las grandes alturas no interfiere con la capacidad normal de reproducción


Assuntos
Menarca , Menopausa , Peru , Climatério , Doença da Altitude/classificação , Doença da Altitude/metabolismo , Doença da Altitude/patologia , Fertilidade , Hipóxia/complicações , Hipóxia/patologia , Reprodução
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