RESUMO
Heterobostrychus aequalis (Waterhouse, 1884) (Coleoptera: Bostrichidae) is considered a severe pest for wood and wood products in regions where it is established. In Brazil, so far, there are no records of its establishment. Therefore, this work reports the interception of this Bostrichidae in the Harbor of Rio de Janeiro, on pallet wood from India. It also defends the maintenance of this insect as an absent quarantine pest (A1), by the Ministry of Agriculture, Livestock and Supply. It also conducts a discussion that addresses the efficiency of wood treatments, usually used to prevent the spread of quarantine pests in environments where there is international transit of wood, demonstrating that they may not be efficient in this regard, especially for insect species that have the capacity to lay eggs on dry wood. In this context, it also suggests population monitoring, combined with inspections, as an aid measure for the early detection of this pest in an environment where there is international transit of wood.
Assuntos
Madeira/parasitologia , Besouros , Brometos/administração & dosagem , Controle de Pragas/métodos , Brasil , Saneamento de PortosRESUMO
Neisseria meningitidis bacterium is a Gram-negative diplococcus. Among their serogroups, the B is one of the main causes of invasive meningococcal disease. Newborns and children are particularly susceptible to this infection because of their immune systems that are still maturing and relatively inexperienced. Thus, further studies on the use of maternal immunization for protection against this disease are needed. The purpose of this study was to evaluate the potential immunogenic antigens from the outer membrane of N. meningitidis serogroup B in outbred mice and the influence of maternal immunization in the offspring, and analyze the adjuvant effect of bilayer fragments of dioctadecyldimethylamonium bromide (DODAB-BF) and hydroxide aluminium (alum) in enhancing antibodies production and transference to offspring. IgG and IgG1, IgG2a and IgG2b subclasses of antibodies in serum from immunized mice and controls were quantified and compared. Immunization by subcutaneous and intramuscular routes exhibited evidence of IgG, and both adjuvants promoted the production of IgG1 and IgG2b that were transferred to the offspring. These antibodies also showed specificity with the outer membrane vesicles from homologous strain and were capable to cross react with different strains. The use of DODAB-BF seems to enhance immune response on mothers and offspring and may have immunological advantages.
Assuntos
Adjuvantes Imunológicos/administração & dosagem , Anticorpos Antibacterianos/sangue , Vacinas Bacterianas/imunologia , Imunidade Materno-Adquirida , Meningite Meningocócica/prevenção & controle , Neisseria meningitidis Sorogrupo B/imunologia , Compostos de Amônio Quaternário/administração & dosagem , Compostos de Alúmen/administração & dosagem , Animais , Vacinas Bacterianas/administração & dosagem , Vacinas Bacterianas/isolamento & purificação , Brometos/administração & dosagem , Modelos Animais de Doenças , Imunização/métodos , Imunoglobulina G/sangue , Injeções Intramusculares , Injeções Subcutâneas , CamundongosRESUMO
The microvascularization of the thyroid gland in rats was studied in animals following ingestion of potassium bromide in various concentrations in drinking water (15, 50 or 100 mg/l) over a period of either 16 or 66 days. Accordingly, animals were divided into six study groups and one control group. Microvascularization was compared among the groups. The pattern of thyroidal follicle distribution within the blood vessels was evaluated by scanning electron microscopy. Animals that ingested potassium bromide presented an increased density and number of meshes in the capillary network of the follicle. The peripheral vessels showed flattening of the walls and in the central portion of the follicle, the distribution of the capillary network did not undergo any morphologic alteration.
Assuntos
Brometos/farmacologia , Microcirculação/ultraestrutura , Compostos de Potássio/farmacologia , Glândula Tireoide/irrigação sanguínea , Administração Oral , Animais , Brometos/administração & dosagem , Feminino , Microcirculação/efeitos dos fármacos , Microcirculação/fisiologia , Microscopia Eletrônica de Varredura , Modelos Animais , Compostos de Potássio/administração & dosagem , Ratos , Ratos Wistar , Glândula Tireoide/ultraestruturaRESUMO
La inducción de secuencia rápida en anestesia es una técnica que debe ser cuidadosamente desarrollada con especial atención a la posibilidad de aspiración del contenido gástrico e hipoxia, por lo que el tiempo en que se realice debe ser acordado al máximo. En el presente estudio controlado, se comparó tanto clínica como aceleromiográficamente las condiciones de intubación, el período de latencia para lograr un bloqueo neuromuscular del 80 por ciento y 100 por ciento medidos por la primera respuesta de un tren de cuatro estímulos de un grupo de pacientes (n=50) ASA I o II escogidos al azar a quienes se les administró rocuronio ó succinilcolina a dosis equipotentes. El tiempo para un bloqueo del 80 por ciento no mostró diferencias estadísticamente significativas (p>0,05), no así para el 100 por ciento del bloqueo, en donde fue menor para el grupo succinilcolina (p<0,05). En cuanto a las condiciones de intubación no se encontraron diferencias significativas. En conclusión, a pesar de las diferencias farmacodinámicas entre ambas drogas, el período de latencia y las condiciones de intubación fueron similares
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Succinilcolina/administração & dosagem , Brometos/administração & dosagem , Inalação , Sistema Digestório , Anestesia , Hipóxia , Sistema Nervoso , Fibras Musculares EsqueléticasRESUMO
Se estudio el efecto de inhalación de Terbutalina y Bromuro de Ipatropio, más Fenoterol, en el tratamiento de la Crisis Asmática, mediante la determinación del volúmen aspiratorio forzado en un (1) segundo pre y post-tratamiento en treinta (30) pacientes, con edades comprendidas entre 12 y 62 años. Se observó una respuesta favorable en el 83.3 por ciento, con una mejoría del 20 por ciento sobre el pico flujo de base. Solamente el 16.7 por ciento (5), no tuvo respuesta mayor del 15 por ciento, de los cuales dos (40 por ciento de estos últimos cinco pacientes) tuvieron efecto paradójico. La respuesta al tratamiento fue independiente de la edad, sexo, antecedentes previos, número de hospitalizaciones anteriores, así como de la clasificación clínica al momento de su ingreso. Concluimos que el uso de estos fármacos por vía inhalatoria, debe ser de elección en el tratamiento de pacientes con Crisis Asmatica.