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Clin Neuropharmacol ; 22(3): 176-9, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10367183

RESUMO

We present the case of a 72-year-old woman with a history of a bipolar mood disorder chronically treated with lithium. Upon having the dose increased, she developed an acute confusional state accompanied by blepharospasm (BS) and apraxia of eyelid opening. Gait instability with frequent falls, pyramid tract signs, and postural tremor in both hands were also evident. On withdrawing lithium, symptoms remitted within 2 weeks. This patient illustrates that BS and apraxia of eyelid opening may be triggered by lithium overdose. Our case warrants the inclusion of lithium in the list of drugs liable to induce such movement disorders.


Assuntos
Antimaníacos/intoxicação , Apraxias/induzido quimicamente , Blefarospasmo/induzido quimicamente , Cloreto de Lítio/intoxicação , Idoso , Antimaníacos/sangue , Transtorno Bipolar/sangue , Transtorno Bipolar/tratamento farmacológico , Pálpebras/efeitos dos fármacos , Pálpebras/fisiopatologia , Feminino , Humanos , Cloreto de Lítio/sangue
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