RESUMO

The activation of the renin-angiotensin-aldosterone cascade is a mechanism that generates high blood pressure. The structure has been identified and can be blocked through specific enzymatic pathways or receptors. We have a diversity of medications that act on this system. It is useful to develop the skill in clinical practice for selecting a drug from a wide variety. Renin-angiotensin system inhibitors share many pharmacological and pharmacokinetic characteristics but not all them are equivalent. Knowledge based on scientific evidence allows the clinician to choose the ideal drug for each patient.

Assuntos

Angiotensinas/antagonistas & inibidores , Antagonistas de Receptores de Mineralocorticoides , Sistema Renina-Angiotensina/efeitos dos fármacos , Renina/antagonistas & inibidores , Antagonistas de Receptores de Angiotensina/antagonistas & inibidores , Inibidores da Enzima Conversora de Angiotensina/farmacologia , Humanos , Hipertensão/tratamento farmacológico , Antagonistas de Receptores de Mineralocorticoides/uso terapêutico