RESUMO
ABSTRACT: Digital papillary adenocarcinoma is a malignant adnexal tumor with a predilection for acral sites. Hidradenoma is a benign solid and cystic sweat gland neoplasm with focal ductal and glandular differentiation and good outcomes. Hidradenomas can occur at acral sites and show papillary structures; for this reason, they are included in the differential diagnosis of digital papillary adenocarcinoma, and immunohistochemistry is a valuable tool in this scenario. We described a case of a 43-year-old man with an epithelial tumor showing papillary structures in the intermediate phalanx of the fourth finger. There was diffuse positivity for p63 and negativity for S100 protein, suggesting that this tumor was an acral hidradenoma with papillary structures.
Assuntos
Acrospiroma , Adenocarcinoma de Células Claras , Adenocarcinoma Papilar , Adenoma de Glândula Sudorípara , Neoplasias Ósseas , Neoplasias da Mama , Carcinoma de Apêndice Cutâneo , Neoplasias Cutâneas , Neoplasias das Glândulas Sudoríparas , Acrospiroma/diagnóstico , Acrospiroma/cirurgia , Adenocarcinoma Papilar/química , Adenocarcinoma Papilar/diagnóstico , Adenocarcinoma Papilar/cirurgia , Adenoma de Glândula Sudorípara/patologia , Adulto , Humanos , Imuno-Histoquímica , Masculino , Proteínas S100 , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/metabolismo , Neoplasias das Glândulas Sudoríparas/cirurgiaRESUMO
Background: Clear cell hidradenoma (acrospiroma) is adnexal tumors that arise from the distal excretory duct of eccrine sweat glands. It is generally defined in humanbeings. It presents solitary structure in firmness nodule. Most frequently are encountered in head, face, and upper extremities in humans. Hidradenomas are called generally by definition benign. Their malignant transformations and metastasis are seen very rarely. In veterinary literature database, the malignant form of tumor has been defined as an unique report in four dogs. They are extremely rare tumors in dogs. It is not documented within multiple tumor complex up to now.Case: In the case, three tumors were detected in a 9-year-old neutered female German shepherd dog. After clinical examination, a complete surgical resection of all masses was performed and masses were sent to Pathology for diagnosis. A mass on the right last rib was a 8x6 cm in diameters with severe ulceration. The mass had a hard texture, immobility and irregular borders. Other masses were localized on the back and left caudo-abdominal mammary lobe. Tumors on the back and the mammary lobe did not invade muscle layer, but the tumor on the last rib aggressively invaded surrounding tissue and were very difficult to remove surgically After macroscopy, all the masses were stained with hematoxylin-eosin (H&E), Mayers mucicarmine and Periodic Acid Shiff (PAS) stainings. In the first mass, there were multilobular epithelial islands between prominent fibrous septa from the upper to deep of dermis. The neoplastic cells were generally round or polyhedral in shape. Some of cytoplasms were eosinophilic at different degree. But cytoplasms were generally finely granular and vesicular or clear in appearance. Some cells had possible glycogen deposits. Nucleus was oval to round and had fine reticular chromatin and a distinct nucleolus.[...](AU)
Assuntos
Animais , Feminino , Cães , Acrospiroma/diagnóstico , Acrospiroma/cirurgia , Acrospiroma/veterinária , Neoplasias das Glândulas Sudoríparas/veterináriaRESUMO
Background: Clear cell hidradenoma (acrospiroma) is adnexal tumors that arise from the distal excretory duct of eccrine sweat glands. It is generally defined in humanbeings. It presents solitary structure in firmness nodule. Most frequently are encountered in head, face, and upper extremities in humans. Hidradenomas are called generally by definition benign. Their malignant transformations and metastasis are seen very rarely. In veterinary literature database, the malignant form of tumor has been defined as an unique report in four dogs. They are extremely rare tumors in dogs. It is not documented within multiple tumor complex up to now.Case: In the case, three tumors were detected in a 9-year-old neutered female German shepherd dog. After clinical examination, a complete surgical resection of all masses was performed and masses were sent to Pathology for diagnosis. A mass on the right last rib was a 8x6 cm in diameters with severe ulceration. The mass had a hard texture, immobility and irregular borders. Other masses were localized on the back and left caudo-abdominal mammary lobe. Tumors on the back and the mammary lobe did not invade muscle layer, but the tumor on the last rib aggressively invaded surrounding tissue and were very difficult to remove surgically After macroscopy, all the masses were stained with hematoxylin-eosin (H&E), Mayers mucicarmine and Periodic Acid Shiff (PAS) stainings. In the first mass, there were multilobular epithelial islands between prominent fibrous septa from the upper to deep of dermis. The neoplastic cells were generally round or polyhedral in shape. Some of cytoplasms were eosinophilic at different degree. But cytoplasms were generally finely granular and vesicular or clear in appearance. Some cells had possible glycogen deposits. Nucleus was oval to round and had fine reticular chromatin and a distinct nucleolus.[...]
Assuntos
Feminino , Animais , Cães , Acrospiroma/cirurgia , Acrospiroma/diagnóstico , Acrospiroma/veterinária , Neoplasias das Glândulas Sudoríparas/veterináriaRESUMO
We bring two cases of hidradenoma papilliferum, rare injury. We describe the clinical, histopathological and a review of the available literature on the condition.
Assuntos
Acrospiroma/patologia , Neoplasias Vulvares/patologia , Acrospiroma/diagnóstico , Acrospiroma/etnologia , Acrospiroma/cirurgia , Adulto , Distribuição por Idade , Glândulas Apócrinas/patologia , Diagnóstico Diferencial , Cisto Epidérmico/diagnóstico , Feminino , Neoplasias dos Genitais Masculinos/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição por Sexo , Doenças da Vulva/diagnóstico , Neoplasias Vulvares/diagnóstico , Neoplasias Vulvares/etnologia , Neoplasias Vulvares/cirurgiaAssuntos
Humanos , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/patologia , Umbigo/patologia , Acrospiroma/diagnóstico , Acrospiroma/patologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Umbigo/cirurgia , Acrospiroma/cirurgia , Diagnóstico DiferencialRESUMO
Reportamos el caso de un espiroadenoma ecrino en una paciente de 90 años de edad, que empezó un año antes de la consulta con una lesión en el párpado. Se trata de un tumor benigno de la glándulas sudoríparas que es raro en el párpado. Al principio pensamos en otro tumor, como el carcinoma sebáceo, por su rápido crecimiento. La posibilidad de un tumor de glándulas sudoríparas debiera considerarse en el diagnóstico de tumores palpebrales.
We report a case of an eccrine spiradenoma in a 90 years old woman, who began a year before with the lesion on the eyelid. It is a begin sweat gland tumor, that is rare on the eyelid. At the beginning we thougth in an other tumor, like sebaceous carcinoma for its quick growth. The possibility of sweat gland tumor should be kept in mind in the diagnosis of eyelid tumours.
Assuntos
Humanos , Feminino , Idoso de 80 Anos ou mais , Acrospiroma/cirurgia , Neoplasias Palpebrais/diagnóstico , Acrospiroma/patologia , Acrospiroma/ultraestruturaRESUMO
Los tumores malignos cutáneos tienen como primera elección la extirpación quirúrgica; es necesario determinar márgenes adecuados para cada tipo de lesión, con la finalidad de evitar recidivas y a la vez conservar el máximo de tejido sano permitido. Para ello existe consenso internacional, basados en la experiencia de cirujanos dermatólogos y en trabajos de investigación clínica sobre cuáles son los márgenes apropiados a cada tumor. Se realiza una revisión de la literatura, obteniendo los márgenes quirúrgicos para las principales neoplasias malignas de piel.
Assuntos
Humanos , Acrospiroma/cirurgia , Carcinoma de Célula de Merkel , Cirurgia de Mohs , Histiocitoma Fibroso Benigno/cirurgia , Melanoma/cirurgia , Recidiva Local de Neoplasia , Neoplasia de Células Basais , Neoplasias CutâneasRESUMO
Eccrine porocarcinoma is a rare tumor of eccrine sweat ducts of the skin. We report a case successfully treated surgically. These tumors hardly have a typical clinical appearance but is easily recognizable histologically. Three morfological variants can be identified: a benign, a premalignant or dysplastic, and an invasive, malignant form. Symptoms such as bleeding, pain and itching are sugestive of a possible malignant transformation. Primary treatment is wide surgical excision. The value of adjunctive therapy has not been proved. Our report and review of the literature illustrate the natural history and pathological finding of this disease