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1.
Arq Bras Oftalmol ; 86(2): 145-150, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35417517

RESUMO

PURPOSE: To investigate ocular surface and meibomian glands in patients with treatment-naive acne vulgaris. METHODS: The Ocular Surface Disease Index (OSDI) questionnaire, invasive tear film breakup time, fluorescein staining of the ocular surface, and Schirmer II test were performed for all subjects. Total eyelid and meibomian gland secretion scores were assessed. Non-contact meibography was performed with the Sirius corneal topographic device. RESULTS: The right eyes of 35 patients with acne vulgaris and 35 healthy volunteers were included the study. While the OSDI and staining scores were significantly higher in the acne group than in the control group (p=0.01 and p=0.003, respectively), the invasive tear film breakup time and Schirmer measurements were significantly lower in the acne group (p=0.000 and p=0.003, respectively). The total eyelid and meibomian gland secretion scores were also higher in the acne group than in the control group (p=0.003 and p=0.000, respectively). On the morphological evaluation of the meibomian glands, the thickening, thinning, tortuosity, and presence of ghost areas were statistically significantly more common in the acne vulgaris group than in the control group (p=0.000, p=0.001, p=0.05, and p=0.006, respectively). The percentage of the meibomian gland loss area was significantly high in the acne vulgaris group on both upper and lower meibography. The meibomian gland loss area positively correlated with total eyelid and meibomian gland secretion scores. CONCLUSION: Acne vulgaris may have a predisposition to meibomian gland dysfunction and ocular surface damage. Early recognition of meibomian gland and ocular surface alterations seems important, especially in acne vulgaris cases for which oral isotretinoin treatment is planned.


Assuntos
Acne Vulgar , Síndromes do Olho Seco , Doenças Palpebrais , Disfunção da Glândula Tarsal , Humanos , Glândulas Tarsais/diagnóstico por imagem , Lágrimas , Acne Vulgar/diagnóstico por imagem , Acne Vulgar/tratamento farmacológico , Doenças Palpebrais/diagnóstico por imagem
2.
J Ultrasound Med ; 33(1): 93-102, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24371103

RESUMO

OBJECTIVES: The purpose of this study was to assess the sonographic morphology of the clinical and subclinical pathology of facial acne vulgaris. METHODS: We studied patients with facial acne vulgaris diagnosed by certified dermatologists, and using a standardized protocol for sonographic examinations, we sequentially described the sonographic pathomorphologic characteristics. Lesions of particular interest to the referring clinician were also analyzed separately. Additionally, acne involvement was staged clinically and sonographically (SOS-Acne) using morphologic definitions of the relevant lesions and predefined scoring systems for gradation of the severity of acne lesions. RESULTS: A total of 245 acne lesions in 20 consecutive patients were studied. Sonographic abnormalities consisted of pseudocysts, folliculitis, fistulas, and calcinosis. Most conditions were subclinical and mostly due to lesion extensions deep into the dermis and hypodermis (52% of pseudocysts and 68% of fistulas). The statistical concordance between acne severity scores assigned by two separate clinicians was strong (κ = 0.8020), but the corresponding sonographic scores generally showed more severe and clinically occult involvement. CONCLUSIONS: Facial acne vulgaris often involves deeper tissues, beyond the reach of the spatially restricted clinical examination; these subclinical conditions can be detected and defined with sonography. Additionally, acne vulgaris is amenable to sonographic scoring.


Assuntos
Acne Vulgar/diagnóstico por imagem , Dermatoses Faciais/diagnóstico por imagem , Pele/diagnóstico por imagem , Ultrassonografia Doppler em Cores/métodos , Algoritmos , Feminino , Humanos , Masculino , Variações Dependentes do Observador , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Adulto Jovem
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