RESUMO
BACKGROUND: Lactobacillus is a genus of Gram-positive non-spore-forming rods usually found in the microbiota of the oral cavity, gastrointestinal tract, and female genitourinary tract. Also, they are commonly used in the food industry as supplements and probiotics. Lactobacilli are normally considered non-pathogenic to the human body, however, under certain circumstances such as immunosuppression, they can cause severe infections, with only a few cases of bacteremia, infective endocarditis, pneumonia, meningitis, and intra-abdominal infections reported. Among these presentations, a pyogenic liver abscess is rather rare. CASE PRESENTATION: We describe the case of a 59-year-old man with a history of diabetes mellitus and multiple abdominal surgeries with the latest being in 2014 presenting with bacteremia and multiple large pyogenic liver abscesses due to Lactobacillus gasseri, which did not appear to be related to the use of probiotics or immunosuppression. CONCLUSIONS: Given the high prevalence of diabetes mellitus and the increased use of probiotics, it is expected that in the future we will see an increase in infections caused by Lactobacilli. Medical management with antibiotics and percutaneous drainage were successful strategies for the treatment of this unusual case of pyogenic liver abscesses and bacteremia caused by Lactobacillus gasseri.
Assuntos
Bacteriemia/diagnóstico , Lactobacillus gasseri/isolamento & purificação , Abscesso Hepático Piogênico/diagnóstico , Antibacterianos/uso terapêutico , Bacteriemia/complicações , Bacteriemia/terapia , Complicações do Diabetes/diagnóstico , Complicações do Diabetes/terapia , Drenagem , Humanos , Lactobacillus gasseri/efeitos dos fármacos , Lactobacillus gasseri/patogenicidade , Abscesso Hepático Piogênico/complicações , Abscesso Hepático Piogênico/terapia , Masculino , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
RESUMEN Se presentó el caso clínico de un anciano de 79 años de edad con alcoholismo crónico y otras comorbilidades asociadas, ingresado por fiebre de tres días de evolución y sospecha de dengue en el Hospital Clínico Quirúrgico Docente "Dr. Ambrosio Grillo Portuondo", de la provincia Santiago de Cuba. Por consenso multidisciplinario se diagnosticó absceso hepático piógeno de los subsegmentos VII-VIII del hígado. Se realizó laparotomía de urgencia con drenaje de la colección purulenta. Presentó infección superficial del sitio operatorio, pero la evolución posoperatoria fue satisfactoria y se egresó curado 7 días después.
ABSTRACT The clinical case of a 79-year-old man with chronic alcoholism and other associated comorbidities presented, admitted with a fever of three days of evolution and suspected diagnosis of dengue at the Hospital Clínico Quirúrgico Docente "Dr. Ambrosio Grillo Portuondo", from Santiago de Cuba province. By multidisciplinary consensus, a pyogenic liver abscess of subsegments VII-VIII of the liver was diagnosed. An emergency laparotomy was performed with drainage of the purulent collection. He presented superficial infection of the surgical site, but the postoperative evolution was satisfactory and he was discharged cured 7 days later.
RESUMO Foi apresentado o caso clínico de um idoso de 79 anos com alcoolismo crónico e outras comorbidades associadas, internado por febre de três dias de evolução e suspeita de dengue no Hospital Clínico Quirúrgico Docente "Dr. Ambrosio Grillo Portuondo", da província de Santiago de Cuba. Por consenso multidisciplinar, foi diagnosticado um abscesso hepático piogênico dos subsegmentos VII-VIII do fígado. Foi realizada laparotomia de emergência com drenagem da coleção purulenta. Apresentou infecção superficial no sítio operatório, mas a evolução pós-operatória foi satisfatória e teve alta curado 7 dias após.
Assuntos
Masculino , Idoso , Abscesso Hepático Piogênico/cirurgia , Abscesso Hepático Piogênico/diagnósticoRESUMO
INTRODUCTION: Liver abscess is a serious and an uncommon pediatric disease. OBJECTIVE AND METHOD: Description of 20 pediatric patients with liver abscess admitted in "Ricardo Gutierrez" Children's Hospital, a Tertiary Reference Center of Buenos Aires, between 2009 and 2015. RESULTS: The hospitalization rate was 35/100.000 admissions. Median age was 5 years old, male/female ratio 4/1. Five patients (25%) had predisposing factors. Median days at diagnosis were 12. FEATURES: Fever 100%, prolonged fever 60%, abdominal pain 50%. The majority had leukocytosis and elevated CRP (median 160 mg/L). Liver enzymes were elevated in only 40% of patients. Ultrasonography detected 90%. A single abscess was observed in 60%; localized at right hepatic lobe, 65%. Purulent material was positive in 12/17 (70%) and bacteremia was present in 3/20 (15%). Wide empirical antibiotic therapy was used. Treatment shift was needed in four patients. The median days of intravenous antibiotics were 30 and the median of total treatment were 53. Surgical procedures were performed in 13/20 (65%). CONCLUSION: Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) was the most frequent pathogen, especially in healthy children that associated skin or respiratory illness. Appropriate antibiotic treatment and eventual drainage allows good outcome without sequela or deaths.
Assuntos
Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/terapia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Abscesso Hepático Piogênico/microbiologia , Masculino , Estudos Retrospectivos , Fatores de RiscoRESUMO
Introduction: Liver abscess is a serious and an uncommon pediatric disease. Objective and Method: Description of 20 pediatric patients with liver abscess admitted in "Ricardo Gutierrez" Children’s Hospital, a Tertiary Reference Center of Buenos Aires, between 2009 and 2015. Results: The hospitalization rate was 35/100.000 admissions. Median age was 5 years old, male/female ratio 4/1. Five patients (25%) had predisposing factors. Median days at diagnosis were 12. Features: Fever 100%, prolonged fever 60%, abdominal pain 50%. The majority had leukocytosis and elevated CRP (median 160 mg/L). Liver enzymes were elevated in only 40% of patients. Ultrasonography detected 90%. A single abscess was observed in 60%; localized at right hepatic lobe, 65%. Purulent material was positive in 12/17 (70%) and bacteremia was present in 3/20 (15%). Wide empirical antibiotic therapy was used. Treatment shift was needed in four patients. The median days of intravenous antibiotics were 30 and the median of total treatment were 53. Surgical procedures were performed in 13/20 (65%). Conclusion: Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) was the most frequent pathogen, especially in healthy children that associated skin or respiratory illness. Appropriate antibiotic treatment and eventual drainage allows good outcome without sequela or deaths.
Resumen Introducción: El absceso hepático es una patología infrecuente en pediatría. Objetivo y Métodos: Describir las características de 20 pacientes ingresados entre 2009-2015 en el Hospital de Niños "R. Gutiérrez", Centro de Referencia de Nivel T erciario de Buenos Aires, Argentina con diagnóstico de absceso hepático. Resultados: La tasa de hospitalización fue 35/100.000 admisiones. La mediana de edad fue 5 años, relación masculino/femenino: 4/1. Cinco pacientes tuvieron factores predisponentes. La mediana de duración de la enfermedad al diagnóstico fue de 12 días. Todos los pacientes presentaron fiebre, 60% síndrome febril prolongado y 50% dolor abdominal. La mayoría tenía leucocitosis y PCR elevada (mediana 160 mg/L). Sólo 40% tuvo alteración de pruebas hepáticas. En 90% de los casos el diagnóstico se realizó por ecografía, 65% estaban localizados en el lóbulo derecho; 60% eran lesiones únicas. Hubo aislamiento microbiológico en 12/17 (70%) y en 3/20 (15%) de hemocultivos. Todos recibieron tratamiento antibacteriano empírico de amplio espectro. La mediana de tratamiento antibacteriano intravenoso fue 30 días y en total 53 días. Se realizó drenaje quirúrgico en 13 casos. Todos evolucionaron favorablemente. Conclusión: Staphylococcus aureus resistente a meticilina de la comunidad (SARM-AC) fue el patógeno predominante, especialmente en niños previamente sanos asociados a un foco cutáneo o respiratorio.
Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/terapia , Estudos Retrospectivos , Fatores de Risco , Abscesso Hepático Piogênico/microbiologiaRESUMO
BACKGROUND: In times of modern surgery, transplantation and percutaneous techniques, pyogenic liver abscess (PLA) has essentially become a problem of biliary or iatrogenic origin. In the current scenario, diagnostic approach, clinical behavior and therapeutic outcomes have not been profoundly studied. This study analyzes the clinical and microbiological features, diagnostic methods, therapeutic management and predictive factors for recurrence and mortality of first episodes of PLA. METHODS: A retrospective single-center study was conducted including 142 patients admitted to the Hospital Italiano de Buenos Aires, between 2005 and 2015 with first episodes of PLA. RESULTS: Prevailing identifiable causes were biliary diseases (47.9%) followed by non-biliary percutaneous procedures (NBIPLA, 15.5%). Seventeen patients (12%) were liver recipients. Eleven patients (7.8%) died and 18 patients (13.7%) had recurrence in the first year of follow up. The isolation of multiresistant organisms (p = 0.041) and a history of cholangitis (p < 0.001) were independent risk factors for recurrence. Mortality was associated with serum bilirubin >5 mg/dL (p = 0.022) and bilateral involvement (p = 0.014) in the multivariate analysis. CONCLUSION: NBPLA and PLA after transplantation may be increasing among the population of PLA in referral centers. History of cholangitis is a strong predictor for recurrence. Mortality is associated to hiperbilirrubinemia and anatomical distribution of the lesions.
Assuntos
Doença Iatrogênica , Abscesso Hepático Piogênico/mortalidade , Abscesso Hepático Piogênico/terapia , Transplante de Fígado/mortalidade , Adulto , Idoso , Argentina , Bilirrubina/sangue , Biomarcadores/sangue , Distribuição de Qui-Quadrado , Colangiopancreatografia por Ressonância Magnética , Colangite/complicações , Bases de Dados Factuais , Feminino , Humanos , Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/microbiologia , Transplante de Fígado/efeitos adversos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada Multidetectores , Análise Multivariada , Razão de Chances , Recidiva , Encaminhamento e Consulta , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Fatores de Tempo , Resultado do TratamentoRESUMO
Background: The pyogenic liver abscess has an incidence of 1.1/1,000 habitants. Mortality can reach 100%. The use of less invasive procedures diminish morbidity and hospital stay. Aim: Identify risk factors in patients who underwent percutaneous drainage guided by ultrasound as treatment. Method: Were analyzed 10 patients submitted to the method. Epidemiological characteristics, laboratory markers and imaging exams (ultrasound and CT) were evaluated. Results: The majority of the patients were men with mean age of 50 years old. Liver disease, alcoholism and biliary tract disease were the most common prodromes. Abdominal pain (90%), fever (70%) and jaundice (40%) were the most common clinical manifestations. Mortality of 20% was observed in this series. Hypoalbuminemia and days of hospitalization had a statistically significant positive association with death. Conclusion: The pyogenic liver abscess has subacute evolution which makes the diagnosis difficult. Image exams have high sensitivity in diagnosis, particularly computed tomography. Percutaneous drainage associated with antibiotic therapy is safe and effective therapeutic resource.
Racional: O abscesso hepático piogênico tem incidência de 1,1 por 1.000 habitantes com mortalidade podendo chegar a 100%. O uso de recursos menos invasivos diminuem morbimortalidade e tempo de internação hospitalar. Objetivo: Identificar fatores de risco no abscesso hepático piogênico tratado por drenagem percutânea guiada por ultrassom. Método: Total de 10 pacientes foram submetidos ao procedimento. Foram avaliadas características epidemiológicas, marcadores laboratoriais exames de imagem (ultrassom e tomografia). Resultados: Na amostra houve predominância do sexo masculino, com média de idade de 50 anos. Hepatopatia, etilismo e doença da via biliar foram os pródromos mais frequentes. Dor abdominal (90%), febre (70%) e icterícia (40%) foram manifestações clínicas mais comuns. Houve mortalidade de 20% nesta série. Hipoalbuminemia e dias de internação hospitalar tiveram associação positiva com óbito estatisticamente significante. Conclusão: O abscesso hepático piogênico tem evolução subaguda o que dificulta o diagnóstico. Exames de imagem têm sensibilidade alta na propedêutica diagnóstica, notadamente a tomografia computadorizada. A drenagem percutânea, associada à antibioticoterapia, mostrou ser recurso terapêutico seguro e eficaz.
Assuntos
Drenagem/métodos , Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/cirurgia , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Cirurgia Assistida por Computador , Ultrassonografia , Adulto JovemRESUMO
ABSTRACT Background: The pyogenic liver abscess has an incidence of 1.1/1,000 habitants. Mortality can reach 100%. The use of less invasive procedures diminish morbidity and hospital stay. Aim: Identify risk factors in patients who underwent percutaneous drainage guided by ultrasound as treatment. Method: Were analyzed 10 patients submitted to the method. Epidemiological characteristics, laboratory markers and imaging exams (ultrasound and CT) were evaluated. Results: The majority of the patients were men with mean age of 50 years old. Liver disease, alcoholism and biliary tract disease were the most common prodromes. Abdominal pain (90%), fever (70%) and jaundice (40%) were the most common clinical manifestations. Mortality of 20% was observed in this series. Hypoalbuminemia and days of hospitalization had a statistically significant positive association with death. Conclusion: The pyogenic liver abscess has subacute evolution which makes the diagnosis difficult. Image exams have high sensitivity in diagnosis, particularly computed tomography. Percutaneous drainage associated with antibiotic therapy is safe and effective therapeutic resource.
RESUMO Racional: O abscesso hepático piogênico tem incidência de 1,1 por 1.000 habitantes com mortalidade podendo chegar a 100%. O uso de recursos menos invasivos diminuem morbimortalidade e tempo de internação hospitalar. Objetivo: Identificar fatores de risco no abscesso hepático piogênico tratado por drenagem percutânea guiada por ultrassom. Método: Total de 10 pacientes foram submetidos ao procedimento. Foram avaliadas características epidemiológicas, marcadores laboratoriais exames de imagem (ultrassom e tomografia). Resultados: Na amostra houve predominância do sexo masculino, com média de idade de 50 anos. Hepatopatia, etilismo e doença da via biliar foram os pródromos mais frequentes. Dor abdominal (90%), febre (70%) e icterícia (40%) foram manifestações clínicas mais comuns. Houve mortalidade de 20% nesta série. Hipoalbuminemia e dias de internação hospitalar tiveram associação positiva com óbito estatisticamente significante. Conclusão: O abscesso hepático piogênico tem evolução subaguda o que dificulta o diagnóstico. Exames de imagem têm sensibilidade alta na propedêutica diagnóstica, notadamente a tomografia computadorizada. A drenagem percutânea, associada à antibioticoterapia, mostrou ser recurso terapêutico seguro e eficaz.
Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Drenagem/métodos , Abscesso Hepático Piogênico/cirurgia , Abscesso Hepático Piogênico/diagnóstico , Estudos Prospectivos , Ultrassonografia , Cirurgia Assistida por ComputadorRESUMO
Spontaneous endoluminal drainage of a pyogenic liver abscess is a rare phenomenon. Similarly, there are only a few cases in the English literature describing hepatic abscesses as an unusual complication of sickle cell anaemia. Having these two phenomena occurring in the same patient is truly a rarity. We describe a case of a 45-year-old man with homozygous sickle cell anaemia who presented to our institution with a pyogenic liver abscess. He had spontaneous drainage of the abscess after spontaneous fistulisation, with the stomach obviating the need for percutaneous drainage.
Assuntos
Anemia Falciforme/complicações , Fístula do Sistema Digestório/etiologia , Fístula Gástrica/etiologia , Abscesso Hepático Piogênico/etiologia , Adulto , Candida albicans/isolamento & purificação , Humanos , Abscesso Hepático Piogênico/diagnóstico , MasculinoRESUMO
Even though Gemella morbillorum infection (GMI) is rare in humans, it may nevertheless, cause endocarditis, meningitis, brain abscess, pleural empyema, nephritis, mediastinitis, and--occasionally--liver abscess. We are describing the case of a 64-years-old Caucasian male admitted with fever and abdominal pain. Laboratory parameters revealed inflammation signs, and instrumental examinations showed the presence of diverticula in the ascending colon. Abdominal ultrasound (US) and computer tomography (CT) showed two focal lesions in the right liver lobe. One had the characteristics of a simple cyst; the second was hypoechoic with a low density area, possibly containing necrotic material. US-guided needle biopsy was found negative for neoplastic cells, showing purulent infiltrate. Pus culture was found positive for GMI. Systemic antibiotic therapy coupled with repeated US-guided needle aspiration, induced the resolution of the hepatic abscess. Few cases have been reported of hepatic abscess caused by GMI in immunocompetent non-cirrhotic subjects.
A pesar de que la infección por Gemella morbillorum (GMI por el término en inglés) es poco común en seres humanos, puede causar endocarditis, meningitis, absceso cerebral, empiema pleural, nefritis, mediastinitis y en ocasiones, absceso hepático. Describimos el caso de un hombre caucásico de 64 años que ingresó con fiebre y dolor abdominal. Los parámetros de laboratorio revelaron signos de inflamación y los exámenes mostraron la presencia de divertículos en el colon ascendente. La ecografía abdominal (US) y la tomografía computarizada (CT) mostró dos lesiones focales en el lóbulo hepático derecho. Una presentó las características de un quiste simple; la segunda fue hipoecóica con una zona de baja densidad, que posiblemente contenía material necrótico. Biopsia con aguja guiada por US dio un resultado negativo para células neoplásicas, mostrando infiltrado purulento. Cultivo de pus fue encontrado positivo para GMI. Una terapia con antibióticos sistémicos, junto con aspiración repetida con aguja guiada por US indujo a la resolución del absceso hepático. Pocos casos se han reportado de absceso hepático causado por GMI en sujetos inmunocompetentes no cirróticos.
Assuntos
Gemella/isolamento & purificação , Infecções por Bactérias Gram-Positivas/terapia , Abscesso Hepático Piogênico/terapia , Antibacterianos/uso terapêutico , Biópsia por Agulha Fina , Infecções por Bactérias Gram-Positivas/diagnóstico , Infecções por Bactérias Gram-Positivas/microbiologia , Humanos , Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/microbiologia , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X , Ultrassonografia de IntervençãoRESUMO
Even though Gemella morbillorum infection (GMI) is rare in humans, it may, nevertheless, cause endocarditis, meningitis, brain abscess, pleural empyema, nephritis, mediastinitis, and - occasionally - liver abscess. We are describing the case of a 64-year-old Caucasian male admitted with fever and abdominal pain. Laboratory parameters revealed inflammation signs, and instrumental examinations showed the presence of diverticula in the ascending colon. Abdominal ultrasound (US) and computer tomography (CT) showed two focal lesions in the right liver lobe. One had the characteristics of a simple cyst; the second was hypoechoic with a low density area, possibly containing necrotic material. US-guided needle biopsy was found negative for neoplastic cells, showing purulent infiltrate. Pus culture was found positive for GMI. Systemic antibiotic therapy, coupled with repeated US-guided needle aspiration, induced the resolution of the hepatic abscess. Few cases have been reported of hepatic abscess caused by GMI in immunocompetent non-cirrhotic subjects.
A pesar de que la infección por Gemella morbillorum (GMI, por el término en inglés) es poco común en seres humanos, puede causar endocarditis, meningitis, absceso cerebral, empiema pleural, nefritis, mediastinitis y en ocasiones, absceso hepático. Describimos el caso de un hombre caucásico de 64 años que ingresó con fiebre y dolor abdominal. Los parámetros de laboratorio revelaron signos de inflamación y los exámenes mostraron la presencia de divertículos en el colon ascendente. La ecografía abdominal (US) y la tomografía computarizada (CT) mostró dos lesiones focales en el lóbulo hepático derecho. Una presentó las características de un quiste simple; la segunda fue hipoecóica con una zona de baja densidad, que posiblemente contenía material necrótico. Biopsia con aguja guiada por US dio un resultado negativo para células neoplásicas, mostrando infiltrado purulento. Cultivo de pus fue encontrado positivo para GMI. Una terapia con antibióticos sistémicos, junto con aspiración repetida con aguja guiada por US indujo a la resolución del absceso hepático. Pocos casos se han reportado de absceso hepático causado por GMI en sujetos inmunocompetentes no cirróticos.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Gemella/isolamento & purificação , Infecções por Bactérias Gram-Positivas/terapia , Abscesso Hepático Piogênico/terapia , Antibacterianos/uso terapêutico , Biópsia por Agulha Fina , Infecções por Bactérias Gram-Positivas/diagnóstico , Infecções por Bactérias Gram-Positivas/microbiologia , Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/microbiologia , Tomografia Computadorizada por Raios X , Ultrassonografia de IntervençãoRESUMO
Reporte de casos:Se recolectaron los datos de las historias clínicas del HUV de 14 niños menores de 15 años de edad con diagnóstico de primera vez de AH con presencia de la triada clínica diagnostica y confirmados ecográficamente. Se analizaron variables como edad, género, procedencia, signos y síntomas, tiempo de evolución, y paraclínicos de diagnóstico al igual que manejo instaurado; encontrándose edad 8,7 años, con diagnóstico de primera vez, 7 masculinos, 11 procedentes del Valle del Cauca, con un tiempo de evolución entre 2 y 30 días (11,2 días) y una estancia hospitalaria entre 6 y 90 días (21,7 días). Otros síntomas incluyeron vómito en 8/14, anorexia y diarrea en 3/14, tos en 2/14 y cefalea y astenia en 1/10. Presentaron desnutrición aguda 3/7, crónica 3/7 y global 5/7. En 13/14 ecografías abdominales se encontraron AH localizados del lado derecho, siendo únicos en 11/13. Otros paraclínicos evidenciaron: hipoalbuminemia en 5/6, incremento de la VES y PCR en 14/14 y alteración de las pruebas de funcionamiento hepático en 3/7. En 9/14 niños los cultivos del material de drenaje de colección identificaron E.coli, S. viridans, S. epidermidis y P. aureginosa. 2/6 presentaron amibas al examen de heces Conclusión:El AH se debe sospechar clínicamente ante la triada fiebre, hepatomegalia y dolor abdominal de predomino en hipocondrio derecho, corroborar su localización y tipo de presentación con una ecografía abdominal, apoyar su diagnóstico con algunos paraclínicos en sangre y heces, e iniciar su pronto y adecuado manejo médico con antiparasitarios y antibióticos siguiendo una adecuada evolución y así evi tar sus complicaciones que pueden ocasionar mayor morbimortalidad.
Case Report:We collected data from medical records of HUVof 14 children under 15 years of age with first-time diagnosis of liver abscess in the presence of the clinical triad diagnosed and confirmed sonographically. We analyzed variables such as age, gender, signs and symptoms, evolution time, clinical and laboratory data for diagnosis as well as established management; finding age 8.7 years ofage with first time diagnosed, 7 male 11 from the Valle del Cauca, with a time between 2 and 30 days (13.5 days) and hospital stay between 6 and 90 days (21,7 days). Other symptoms included vomiting in 8 /14, anorexia and diarrhea in 3/14, cough in 3/14, and headache and asthenia in 1 / 10. Acute malnutrition showed 3 / 7, chronic 3 / 7, global 5 / 7. The abdominal ultrasounds were located AH on the right, being unique in 11/13. Other paraclinical showed: albumin in 5 / 6, increased ESR and CRP 14/14 and impaired liver function tests in 3 / 7. In 9 / 14 children's material culture collection identified drainage E. coli, S. viridans, S. epidermidis and P. aeruginosa. 3 / 6 presented amoebas to stool examination. Medical management lasted between 10 and 42 days (17.7 days) with antibiotics such as oxacillin, clindamycin, metronidazole, amikacin, ceftriaxone, cefotaxime, ampicillin-sulbactam, piperacillintazobactam, metronidazole being used in 13 / 14. 9 / 10 required surgical drainage guided by ultrasound.Conclusion:The AH should be suspected clinically with the triad fever, hepatomegaly and right upper quadrant abdominal pain, verify their location and type of presentation with an abdominal ultrasound, supporting some paraclinical diagnosis with blood and feces, and initiate a prompt and suitable worming and medical treatment with appropriate antibiotics following developments, thereby avoiding the complications that can lead to increased morbidity and mortality.
Assuntos
Masculino , Adolescente , Feminino , Lactente , Pré-Escolar , Criança , Abscesso Hepático Amebiano/classificação , Abscesso Hepático Amebiano/diagnóstico , Abscesso Hepático/classificação , Abscesso Hepático/diagnóstico , Amebíase , Abscesso Hepático Piogênico/classificação , Abscesso Hepático Piogênico/diagnósticoRESUMO
There are few studies reporting pyogenic liver abscess (PLA) caused by Streptococcus constellatus in the medical literature. S. constellatus is a comensal microorganism that belongs to the Streptococcus milleri's bacteria group and is not considered to be pathogenic for humans. We report the case of a 23-year-old man with a 15-days history of abdominal pain in the right flank followed by daily fever, chills, nausea, vomits, sialism and jaundice. Physical examination revealed moderate jaundice (2+/4+), abdominal distention, generalized pain and tender over the right flank with positive Blumberg's sign. Additionally, the liver was palpable 5 cm below the costal margin in the right midclavicular line. Abdominal Computerized Tomography showed multiple hypodense hepatic images suggestive of liver abscesses. The patient underwent surgical exploration of the abdomen through a sub-costal incision and, during operation ruptured abscess localized on the hepatic segment III was drained. Culture of the purulent material obtained at surgery yielded Streptococcus constellatus as the causative agent. Liver abscess is a potential life-threatening disease that must be treated as soon as possible with invasive approaches, if necessary, and bacteriological studies performed when possible, allowing isolation of causative agents and specific antibiotic therapy.
Assuntos
Abscesso Hepático Piogênico/diagnóstico , Abscesso Hepático Piogênico/microbiologia , Infecções Estreptocócicas/diagnóstico , Infecções Estreptocócicas/microbiologia , Streptococcus constellatus , Antibacterianos/uso terapêutico , Brasil , Terapia Combinada , Humanos , Fígado/diagnóstico por imagem , Fígado/microbiologia , Fígado/cirurgia , Abscesso Hepático Piogênico/terapia , Masculino , Infecções Estreptocócicas/terapia , Streptococcus constellatus/isolamento & purificação , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Adulto JovemRESUMO
Pyogenic liver abscess is still considered a medical challenge due to the seriousness of the clinical course, late diagnosis, and usually high mortality. Gas-forming liver abscess is not uncommon, the incidence among all pyogenic liver abscess is around 7 to 24 %, mostly in individuals in their sixth and seventh decades ,and with diabetes mellitus disease. The epidemiology of gas-forming liver abscess has been changing with a shift from young to older diabetic adults. A clinical case of a 71 year old diabetic female with gas-forming liver abscess is presented; we describe the clinical course and treatment is analyzed.