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Background: A heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC). Methods: A population-based case-control study was conducted. Children <18 years old, newly diagnosed with ALL and residents of GMC were included. Controls were patients without leukemia recruited from second-level public hospitals, frequency-matched by sex, age, and health institution with the cases. The residence address where the patients lived during the last year before diagnosis (cases) or the interview (controls) was used for geolocation. Kulldorff's spatial scan statistic was used to detect spatial clusters (SCs). Relative risks (RR), associated p-value and number of cases included for each cluster were obtained. Results: A total of 1054 cases with ALL were analyzed. Of these, 408 (38.7%) were distributed across eight SCs detected. A relative risk of 1.61 (p<0.0001) was observed for the main cluster. Similar results were noted for the remaining seven ones. Additionally, a proximity between SCs, electrical installations and petrochemical facilities was observed. Conclusions: The identification of SCs in certain regions of GMC suggest the possible role of environmental factors in the etiology of childhood ALL.

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BACKGROUND: The urban population health initiative was designed as a multidisciplinary, multisector programme to address cardiovascular (CV) disease, specifically hypertension and its underlying causes in the cities of Ulaanbaatar, Mongolia; Dakar, Senegal; and São Paulo, Brazil. This article aims to provide an overview of the history and dynamics of CV disease policy making in the three countries, to present the policy reform contributions of the initiative and its role in the policy agenda-setting framework/process in each country and to identify the enablers and challenges to the initiative for doing so. METHODS: A qualitative case study was conducted for each setting from November 2020 to January 2021, comprised of a document review, semi-structured in-depth interviews and unstructured interviews with stakeholders involved in the initiative. The literature review included documents from the initiative and the peer-reviewed and grey literature with a total of 188 documents screened. Interviews were conducted with 21 stakeholders. Data collection and thematic analysis was guided by (i) the Kingdon multiple streams conceptual framework with the main themes being CV disease problems, policy, politics and the role of policy entrepreneurs; and (ii) the study question inquiring on the role of the urban population health initiative at the CV disease policy level and enabling and challenging factors to advancing CV disease policy. Data were thematically analysed using the Framework Method. RESULTS: Each setting was characterized by a high hypertension and CV disease burden combined with an aware and proactive political environment. Policy outcomes attributed to the initiative were updating the guidelines and/or algorithms of care for hypertension and including revised physical and nutritional education in school curricula, in each city. Overall, the urban health initiative's effects in the policy arena, were most prominent in Mongolia and Senegal, where the team effectively acted as policy entrepreneur, promoting the solutions/policies in alignment with the most pressing local problems and in strong involvement with the political actors. The initiative was also involved in improving access to CV disease drugs at primary health levels. Its success was influenced by the local governance structures, the proximity of the initiative to the policy makers and the local needs. In Brazil, needs were expressed predominantly in the clinical practice. CONCLUSIONS: This multi-country experience shows that, although the policy and political environment plays its role in shaping initiatives, often the local priority needs are the driving force behind wider change.

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ABSTRACT PURPOSE To describe and analyze the healthiness of formal and informal food establishments in bus terminals of the metropolitan region of the state of Rio de Janeiro. METHOD An audit was conducted in 156 formal and 127 informal food establishments located in 14 bus terminals of the five most populous cities of the metropolitan region of Rio de Janeiro. Proportions of types of establishments and means (95%CI) of food availability indicators in formal and informal settings were calculated. For the formal setting, prices, proportions of accepted payment methods, days and hours of operation, and food categories with displayed advertising were described. RESULTS The healthiness of food establishments in bus terminals was low (less than 36%). On average, ultra-processed food subgroups were 250% more available for purchase than fresh or minimally processed food. Purchasing food at these places was convenient because several forms of payment were available, and the opening hours of the establishments followed the peaks of movement. In addition, 73.3% of the advertising referred to ultra-processed drinks, and the cost-benefit of buying ultra-processed food was better than fresh or minimally processed food. CONCLUSION The food environment of bus terminals in the metropolitan region of Rio de Janeiro promotes unhealthy eating. Regulatory public policies should focus on initiatives to limit the wide availability and advertising of ultra-processed food in spaces of great circulation of people.

RESUMO OBJETIVO Descrever e analisar a saudabilidade dos estabelecimentos com venda formal e informal de alimentos em terminais rodoviários da região metropolitana do Rio de Janeiro. MÉTODOS Realizou-se auditoria em 156 estabelecimentos formais e 127 pontos informais de venda de alimentos localizados em 14 terminais rodoviários das cinco cidades mais populosas da região metropolitana do Rio de Janeiro. Foram calculadas proporções de tipos de estabelecimentos e médias (IC95%) de indicadores de disponibilidade de alimentos nos ambientes formal e informal. Para o ambiente formal, foram descritos preços, proporções das formas de pagamento aceitas, dias e horários de funcionamento e categorias de alimentos com propaganda exposta. RESULTADOS A saudabilidade dos pontos de venda de alimentos nos terminais rodoviários era baixa (inferior a 36%). Em média, estavam disponíveis para compra 250% mais subgrupos de alimentos ultraprocessados do que in natura ou minimamente processados. Adquirir comida nesses locais era conveniente porque diversas formas de pagamento estavam disponíveis e os horários de funcionamento dos estabelecimentos acompanhavam os picos de movimentação. Além disso, 73,3% das propagandas se referiam a bebidas ultraprocessadas e o custo-benefício da compra de alimentos ultraprocessados era melhor que o de alimentos in natura ou minimamente processados. CONCLUSÃO O ambiente alimentar dos terminais rodoviários da região metropolitana do Rio de Janeiro promove uma alimentação não saudável. Políticas públicas de regulação devem se concentrar em iniciativas que limitem a ampla disponibilidade e publicidade de alimentos ultraprocessados nesses espaços de grande circulação de pessoas.

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Introducción: la automedicación en salud bucal es una práctica censurada por la biomedicina; sin embargo, es una actividad frecuente que sintetiza la interacción de las personas con diferentes modelos de atención a la salud, en donde se materializa la trama estructural y simbólica del campo sanitario. El objetivo de este estudio fue comprender los saberes y prácticas sobre automedicación salud bucal en Bogotá. Métodos: investigación cualitativa con enfoque etnográfico. Se utilizaron herramientas como observación participante, entrevista etnográfica y diario de campo. Se eligieron siete familias de Bogotá a partir de una muestra tipológica ideal. Resultados: existen barreras de acceso a la atención odontológica que se incrementan a través de mecanismos de segregación que se relacionan con la estructura urbana de la ciudad, barreras que motivan la utilización de diversos medicamentos frente a las dolencias. La boca tiene diversos significados. Se reconoce la caries y sus efectos, y en su prevención se usan sedas, pastas, enjuagues y cepillos, elementos que proceden de la industria farmacéutica. El padecimiento más común es la odontalgia y para tratarla se utilizan principalmente analgésicos de origen farmacéutico. Conclusiones: la automedicación en salud bucal es un proceso consciente que realizan los sujetos desde sus propios razonamientos y recursos, con el propósito de prevenir y atender sus dolencias. Esta práctica se relaciona con las representaciones sociales sobre la boca, con el acceso a los servicios de atención odontológica, y con la disposición y obtención de insumos terapéuticos.

Introduction: self-medication in oral health is a practice censured by biomedicine; however, it is a frequent activity that synthesizes the interaction of people with different models of health care, where the structural and symbolic fabric of the health field materializes. The objective was to understand the knowledge and practices on oral health self-medication in Bogota. Methods: qualitative research with ethnographic approach. Tools such as participant observation, ethnographic interview and field diary were used. Seven families from Bogota were chosen from an ideal typological sample. Results: there are barriers to access to dental care that are increased through segregation mechanisms that are related to the urban structure of the city, barriers that motivate the use of various medications in the face of ailments. The mouth has diverse meanings. Caries and its effects are recognized, and in its prevention silks, pastes, rinses and brushes are used, elements that come from the pharmaceutical industry. The most common ailment is odontalgia, and analgesics of pharmaceutical origin are mainly used to treat it. Conclusions: self-medication in oral health is a conscious process carried out by the subjects from their own reasoning and resources, to prevent and treat their ailments. This practice is related to social representations about the mouth, to access to dental care services, and to the availability and obtaining of therapeutic supplies.

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Objectives: Rural residents are exposed to many risk factors for poor diet quality, such as low socioeconomic status and food insecurity. However, the differences between urban and rural residents regarding the association of fruit and vegetable consumption with cognitive performance have not been explored. The aim of this study was to investigate the association of fruit and vegetable consumption with cognitive performance in urban and rural areas in a nationally representative sample of Brazilian older adults. Methods: The sample included 9,412 adults aged 50 years or older from the Brazilian Longitudinal Study of Aging (Estudo Longitudinal da Saúde dos Idosos Brasileiros [ELSI]). The association between consumption of fruits and vegetables and cognitive performance was evaluated using linear regression. Results: In 8,158 participants (mean age 61.6 ± 9.3 years, 54% women, 44% White, and 15% from rural areas), the mean frequency of fruit and vegetable consumption was 2.0 ± 1.3 times a day. Higher intake of fruits and vegetables was associated with better memory (β = 0.031, 95%CI 0.014-0.049), verbal fluency (β = 0.030, 95%CI 0.004-0.056), and global cognition (β = 0.035, 95%CI 0.015-0.055) performance in urban, but not rural residents (p for interaction = 0.036). Conclusion: Higher frequency of fruit and vegetable intake was associated with better cognitive performance in urban, but not in rural areas in Brazil.

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Objective: To analyze the behavior of pesticide poisoning associated with lethality in rural and urban populations in Colombia from 2007 to 2017. Methodology: Retrospective observational study that included a descriptive cross-sectional study and an ecological design that analyzed aggregate measures of morbidity, mortality, and risk attributable to the population in rural and urban areas. In the cross-sectional study, the relative risk was estimated to measure the factors associated with lethality among intoxications using Poisson regression with logarithmic function. For the time series, the trends were established with simple linear regression, and the seasonal decomposition was performed using the multiplicative model. Autocorrelations were tested using the Box-Ljung statistic. Results: Between 2007-2017; 89 490 cases were reported. The Morbidity due to poisoning showed a higher proportion in the rural population 36.03 cases per 100 000; this indicator was three times higher than in urban areas (12.33 cases per 100 000). The mortality rates in rural and urban areas were 1.00 and 0.13 cases per 100 000, respectively. The relative risk of fatality in case of intoxication was associated with the intention of suicide in the rural population Relative Risk (RR): 5.9 (95% CI: 5.0-6.9). Conclusion: A higher proportion of lethality associated with these events occurred in populations living in rural areas and reporting cases of suicidal intent. In addition, morbidity and mortality due to pesticide poisoning had the highest proportion in rural areas and a growing trend over time.

Objetivo: Analizar el comportamiento de las intoxicaciones por plaguicidas en poblaciones rurales y urbanas asociadas a la letalidad en Colombia durante 2007-2017. Metodología: Estudio observacional retrospectivo que incluyó: un estudio descriptivo transversal y un diseño ecológico que analizó medidas agregadas de morbilidad, mortalidad y riesgo atribuibles a la población en áreas rurales y urbanas. En el estudio transversal se estimó el riesgo relativo para medir los factores asociados a la letalidad entre las intoxicaciones mediante regresión de Poisson con función logarítmica. Para la serie de tiempo, las tendencias se establecieron con regresión lineal simple y la descomposición estacional se realizó mediante el modelo multiplicativo. Las autocorrelaciones se probaron mediante el estadístico Box-Ljung. Resultados: Entre 2007-2017; Se notificaron 89 490 casos. La Morbilidad por intoxicación presentó mayor proporción en la población rural 36,03 casos por 100 000; este indicador fue tres veces mayor que en las áreas urbanas (12,33 casos por 100 000). Las tasas de mortalidad en el área rural y urbana fueron de 1,00 y 0,13 casos por 100 000, respectivamente. El riesgo relativo de fatalidad en caso de intoxicación se asoció con la intención de suicidio en la población rural RR: 5,9 (IC 95%: 5,0-6,9). Conclusión: Una mayor proporción de letalidad asociada a estos eventos ocurrió en poblaciones que viven en áreas rurales y reportan casos de intención suicida. Además, la morbilidad y mortalidad por intoxicación por plaguicidas tuvo la mayor proporción en las zonas rurales y una tendencia creciente en el tiempo.

Objetivo: Analisar o comportamento das intoxicações por agrotóxicos em populações rurais e urbanas associadas à letalidade na Colômbia durante 2007-2017. Metodologia: Estudo observacional retrospectivo que incluiu: estudo transversal descritivo e delineamento ecológico que analisou medidas agregadas de morbidade, mortalidade e risco atribuíveis à população em áreas rurais e urbanas. No estudo transversal, o risco relativo foi estimado para medir os fatores associados à letalidade entre as intoxicações por meio da regressão de Poisson com função logarítmica. Para as séries temporais, as tendências foram estabelecidas com regressão linear simples e a decomposição sazonal foi realizada usando o modelo multiplicativo. As autocorrelações foram testadas usando a estatística Box-Ljung. Resultados: Entre 2007-2017; 89.490 casos foram notificados. A Morbidade por intoxicação apresentou maior proporção na população rural 36,03 casos por 100.000; este indicador foi três vezes superior ao das zonas urbanas (12,33 casos por 100 000). As taxas de mortalidade nas áreas rural e urbana foram de 1,00 e 0,13 casos por 100.000 habitantes, respectivamente. O risco relativo de fatalidade em caso de intoxicação associou-se à intenção de suicídio na população rural RR: 5,9 (IC 95%: 5,0-6,9). Conclusão: Maior proporção de letalidade associada a esses eventos ocorreu em populações residentes em áreas rurais e com relato de casos de intenção suicida. Além disso, a morbimortalidade por intoxicação por agrotóxicos teve maior proporção na zona rural e tendência crescente ao longo do tempo.

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Introducción: Anualmente se pierden 1,35 millones de vidas por causa de siniestros viales; su ocurrencia se ha relacionado, además de factores comportamentales, con desigualdades sociales. Objetivo: Analizar las desigualdades sociales urbano-rurales en la mortalidad por siniestros viales en Colombia para el periodo 1998-2019. Materiales y métodos: Estudio ecológico a partir del análisis de las tasas de mortalidad ajustadas de los grupos poblacionales urbanos y rurales estratificados por sexo. Se hicieron análisis con regresión de Joinpoint y se calcularon medidas de desigualdad simple absoluta y relativa. Resultados: Se registraron 139 323 muertes por siniestros viales, en Colombia la tasa de mortalidad por esta causa se ha venido reduciendo. En contraste con las áreas rurales, en las áreas urbanas esta reducción es más significativa. Existen desigualdades en la mortalidad entre las áreas urbanas y rurales que han venido estrechándose. No obstante, en el caso de hombres y mujeres ha venido incrementándose. Discusión: La reducción de la tasa de mortalidad por siniestros viales sugiere que las intervenciones en seguridad vial han sido efectivas. La mayor mortalidad en hombres puede explicarse a partir de factores comportamentales. Las desigualdades urbano-rurales pueden estar relacionadas con las dinámicas de desarrollo. Conclusiones: Se registra una reducción en la tasa de mortalidad por siniestros viales, la cual es más significativa en áreas urbanas. Existen desigualdades urbano-rurales en la mortalidad por esta causa. Las políticas de seguridad vial deben partir de un enfoque integrador vinculado con otras agendas políticas.

Introduction: Annually, 1,35 million lives are lost due to road accidents; their occurrence has been related, in addition to behavioral factors, to social inequalities. Objective: To analyze urban-rural social inequalities in mortality from traffic accidents in Colombia from 1998-2019. Methods and materials: Ecological study based on the analysis of standardized mortality rates adjusted for age and sex of urban and rural population groups stratified by sex. Joinpoint regression analyses were performed, and absolute and relative simple inequality measures were calculated. Results: There were 139.323 deaths from road accidents; in Colombia mortality rates from this cause has been decreasing. In urban areas, the reduction is more significant than in rural areas. Disparities in mortality between urban and rural areas have been narrowing, however, in the case of men and women, they have been increasing. Discussion: Reducing the mortality rate from road accidents suggests that road safety interventions have been effective. Behavioral factors can explain the higher mortality in men. Urban-rural inequalities can be related to development dynamics. Conclusions: There is a significant reduction in the mortality rate due to road accidents in urban areas. There are urban-rural inequalities in mortality from this cause. Road safety policies must be based on an integrative approach linked to other political agendas.

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OBJECTIVES: Rural residents are exposed to many risk factors for poor diet quality, such as low socioeconomic status and food insecurity. However, the differences between urban and rural residents regarding the association of fruit and vegetable consumption with cognitive performance have not been explored. The aim of this study was to investigate the association of fruit and vegetable consumption with cognitive performance in urban and rural areas in a nationally representative sample of Brazilian older adults. METHODS: The sample included 9,412 adults aged 50 years or older from the Brazilian Longitudinal Study of Aging (Estudo Longitudinal da Saúde dos Idosos Brasileiros [ELSI]). The association between consumption of fruits and vegetables and cognitive performance was evaluated using linear regression. RESULTS: In 8,158 participants (mean age 61.6 ± 9.3 years, 54% women, 44% White, and 15% from rural areas), the mean frequency of fruit and vegetable consumption was 2.0 ± 1.3 times a day. Higher intake of fruits and vegetables was associated with better memory (ß = 0.031, 95%CI 0.014-0.049), verbal fluency (ß = 0.030, 95%CI 0.004-0.056), and global cognition (ß = 0.035, 95%CI 0.015-0.055) performance in urban, but not rural residents (p for interaction = 0.036). CONCLUSIONS: Higher frequency of fruit and vegetable intake was associated with better cognitive performance in urban, but not in rural areas in Brazil.

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Abstract Background Genetic variants play a pathophysiological role in headaches, especially in migraine. The Mennonite group (MG) has been geographically and genetically isolated throughout its history, harboring a distinctive distribution of diseases. Objective To determine the characteristics of headaches in a group with direct Mennonite ancestry contrasting with other urban community members (control group [CG]). Methods Subjects with headaches were asked to complete a questionnaire covering: the type of headache, presence of aura, frequency and duration of attacks, pain location and severity, analgesic consumption, premonitory and postdromic manifestations, Depressive Thoughts Scale, Epworth Sleepiness Scale (ESS), General Anxiety Disorder-7, Patient Health Questionnaire-9 (PHQ-9), Migraine Disability Assessment, and Composite Autonomic System Score. Results We included 103 participants (CG: 45, Mennonite group [MG]: 58). Migraine was the most common headache (CG: 91.1%; MG: 81.0%; p = 0.172), followed by tension-type headache (CG: 8.9%; MG: 15.5%; p = 0.381). Aura was identified by 44.4% and 39.7% in the CG and MG, respectively (p = 0.689). The groups differed only concerning the frequency of retro-orbital pain (CG: 55.6%; MG: 32.8%; p = 0.027), PHQ-9 (CG: median 7, range 0 to 22; MG: median 5, range 0 to 19; p = 0.031) and ESS (CG: median 0, range 0 to 270; MG: median 0, range 0 to 108; p = 0.048) scores. Conclusion There were no major differences in the prevalence and clinical characterization of headaches between the MG and the CG. However, the latter showed more diffuse pain, sleepiness, and depressive symptoms. Specific genetic or epigenetic variants in Mennonite descendants might account for these differences.

Resumo Antecedentes Variantes genéticas desempenham um papel fisiopatológico nas cefaleias, especialmente na migrânea. O grupo menonita (GM) tem estado geográfica e geneticamente isolado ao longo de sua história, abrigando uma distribuição distinta de doenças. Objetivo Determinar as características das cefaleias em um grupo com ascendência menonita direta, comparando-as com as de outros membros da comunidade urbana (grupo controle [GC]). Métodos Participantes com cefaleia foram convidados a preencher um questionário abrangendo: tipo de cefaleia; presença de aura; frequência e duração dos ataques; localização e gravidade da dor; consumo de analgésicos; manifestações premonitórias e posdrômicas; Escala de Pensamentos Depressivos; Escala de Sonolência de Epworth (ESS); Transtorno de Ansiedade Geral-7 (GAD-7); Questionário de Saúde do Paciente-9 (PHQ-9); Avaliação de Incapacidade da Migrânea (MIDAS) e Escore do Sistema Autônomo Composto (COMPASS-31). Resultados Incluímos 103 participantes (GC: 45, GM: 58). A migrânea foi a cefaleia mais frequente (GC: 91,1%; GM: 81,0%; p = 0,172), seguida pela cefaleia tensional (GC: 8,9%; GM: 15,5%; p = 0,381). Aura foi identificada por 44,4% e 39,7% nos GC e GM, respectivamente (p = 0,689). Os grupos diferiram apenas com relação à frequência de dor retro-orbitária (GC: 55,6%; GM: 32,8%; p = 0,027), PHQ-9 (GC: mediana 7, amplitude 0 a 22; GM: mediana 5, amplitude 0 a 19; p = 0,031) e ESS (GC: mediana 0, amplitude 0 a 270; GM: mediana 0, amplitude 0 a 108; p = 0,048). Conclusão Não houve diferenças significativas na prevalência e caracterização clínica das cefaleias nos GM e GC. Entretanto, o último grupo mostrou mais dor difusa, sonolência e sintomas depressivos. Variantes genéticas ou epigenéticas específicas em descendentes de menonitas podem justificar tais diferenças.

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OBJECTIVE: To assess the association between residence place, socioeconomic conditions and oral health-related quality of life (OHRQoL) among schoolchildren from southern Brazil. METHODS: Participants were 9-14-year-old schoolchildren from rural and urban municipal schools from Rosário do Sul, Brazil. The Child Perceptions Questionnaire (CPQ11-14) was used to assess OHRQoL. A structured questionnaire collected data on sociodemographic condition (family income), residence place (urban or rural), use of dental services, and behavioral variables. Clinical oral examination recorded the presence of missing teeth and the gingival bleeding index. Multilevel Poisson regression analysis with a hierarchical approach assessed the association between predictors and CPQ11-14 scores. Rate ratios (RR) and 95% confidence intervals (CI) were estimated. RESULTS: A total of 373 schoolchildren were included (rural area=122; urban area=251), with a mean CPQ11-14 score of 11.83, ranging from 0 to 42. Low-income schoolchildren living in rural areas had 15% higher CPQ11-14 scores than high-income schoolchildren living in urban areas. In urban areas, family income predicted OHRQoL, with low-income schoolchildren having 9% higher CPQ11-14 scores than high-income children. In rural areas, schoolchildren with low household income had 19% higher CPQ11-14 scores than high-income children. CONCLUSION: Schoolchildren from low-income families had a poorer OHRQoL irrespective of their area of residence (rural or urban). The association between family income and OHRQoL was more pronounced among children living in rural areas.

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BACKGROUND: In 2021, WHO notes that globally, 32% of annual deaths worldwide are due to cardiovascular causes, which have been attributed to excessive sodium intake, and therefore recommends a reduction in salt intake to less than 5 g/day. Ecuador does not have data on sodium consumption in the population. Hence, this study sought to determine the association between sodium consumption and sociodemographic variables in subjects living in urban areas of Ecuador. OBJECTIVES: Determine the main dietary sources of sodium in subjects living in urban areas of the Coast and Highlands of Ecuador, and the association between sodium intake and sociodemographic variables such as: sex, region, marital status, socio-economic and educational level of this population. METHODS: Sodium intake was studied in 800 subjects of both sexes aged 15 to 65 years living in urban areas in Ecuador, originating from the Latin American Nutrition and Health Study (ELANS) between 2014 and 2015. Data were obtained through two 24-hour recalls, and were accessed according to sex, region, age, marital status, socio-economic and educational levels. RESULTS: The mean sodium intake was 4900 mg/day (SD ± 1188.32 mg/day), and both sexes exceeded the recommendations. Adjusting for energy intake, sodium consumption is higher in participants aged 50-65 years, from low socio-economic status and with basic education level. A positive relationship was found between sodium and energy intake. Around 48% of the sodium sources included the spices, condiments and herbs group. Within this group, salt itself constitutes 99% of sodium sources. CONCLUSIONS: The Ecuadorian population consumes more than double the sodium recommendations, which vary according to gender and age. The first source of sodium is salt itself, which is part of spices and condiments food group. This data is important to formulate public health policies and interventions in Ecuador, especially in the population at risk.

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Objective: Identify mechanisms reported in primary health care (PHC) interventions in rural and marginal urban populations from 1997 to 2019. Methods: A scoping review was used to identify the literature. The literature search was conducted using the Medline (PubMed and Ovid), Global Health, Embase, Web of Science, Scopus, and Lilacs databases. Inclusion criteria considered literature on primary intervention and observational studies using qualitative, quantitative, or mixed methods. Articles in English, Portuguese, and Spanish published from 1997 to 2019 were included. Rayyan QCRI was used for definitive document selection; sources of information from gray literature or research in progress were excluded. Results: At the individual level, three groups of mechanisms were identified: levels of relationships between interventions and subjects, transformations that can occur in individuals, and reciprocal relationships. At the institutional level, mechanisms were related to temporality, money, power relations, trust relations, the health system, expectations, and administrative conditions. Conclusions: Individual mechanisms are similar in different contexts. Institutional mechanisms are susceptible to variations in context and are expressed in terms of temporality, economic resources, power and trust relations, the health system, expectations, and administrative conditions.

Objetivo: Identificar os mecanismos relatados nas intervenções de atenção primária à saúde (APS) em populações rurais e urbanas periféricas entre 1997 e 2019. Métodos: Foi utilizado o método de revisão sistemática exploratória para identificar a literatura. A busca bibliográfica foi feita nas bases de dados Medline (Pubmed e Ovid), Global Health, Embase, Web of Science, Scopus e Lilacs. A inclusão da literatura considerou estudos de intervenção primária, observacionais, com metodologias qualitativas, quantitativas ou mistas. Foram incluídos artigos em inglês, português e espanhol publicados entre 1997 e 2019. Para a seleção dos documentos definitivos foi utilizado o Rayyan QCRI e foram excluídas fontes de informação da literatura cinzenta ou de pesquisas em andamento. Resultados: No nível individual, foram identificados três grupos de mecanismos: níveis de relações entre as intervenções e os sujeitos, transformações que podem ocorrer nos indivíduos e relações recíprocas. No nível institucional, se relacionaram a temporalidade, dinheiro, relações de poder, relações de confiança, sistema de saúde, expectativas e condições administrativas. Conclusões: Os mecanismos individuais são semelhantes nos diferentes contextos. Os mecanismos institucionais são suscetíveis à variação do contexto e estão representados na temporalidade, nos recursos econômicos, nas relações de poder e confiança, no sistema de saúde, nas expectativas e nas condições administrativas.

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The FCV-19S was the first instrument designed to assess the severity of fear related to COVID-19 and has already been validated in many languages. The objective of this study was to evaluate the homogeneity and construct validity of the 5-item version of the FCV19S, using an online questionnaire in 599 people. The participants' age ranged from 18 to 65 years. Age, gender, marital status, educational level, employment status, and socioeconomic status were analyzed. In the evaluation process we assessed interitem correlation, item rest-correlation, confirmatory factor analysis: Root Mean Square Error of Approximation, Comparative Fix Index, Tucker-Lewis Index; internal consistency (Cronbach's alpha, McDonald's omega), and the Rasch model was assessed for learning more about the psychometric properties of the scale, which allows a detailed knowledge of the strengths and weaknesses of a scale. The FCV-5S has adequate psychometric indicators from the perspective of the Classical Theory of Items. The major limitations were using a self-reported measure and having a convenience sample not necessarily representative of the general population of Argentina.

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ABSTRACT Background: The American cutaneous leishmaniasis (ACL) is expanding in peri-urban environments. Methods: An entomological survey was conducted in the area of the occurrence of an autochthonous urban case of ACL. Sandflies and a parasitological slide of the human case were submitted for molecular diagnosis. Results: Nyssomyia whitmani and Ny. antunesi were the most frequently collected species. Ny. whitmani and Bichromomyia flaviscutellata were positive for Leishmania guyanensis and L. lainsoni, respectively. The human case tested positive for L. lainsoni. Conclusions: Sandflies and Leishmania parasites present in urban forest may occur frequently in nearby domiciliary environments; thus, these areas must be monitored.

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Abstract This article aims to identify the prevalence of and factors associated with dynapenic abdominal obesity (DAO) in older adults in a city in the northern region of Brazil. A cross-sectional study was conducted with 382 community-dwelling older adults in Macapa, Amapa, Brazil. Socioeconomic, clinical, and health information were collected using a structured form. DAO was defined as a combination of dynapenia (handgrip strength of < 26 kgf for men and < 16 kgf for women) and abdominal obesity (abdominal circumference > 102 cm for men and > 88 cm for women). Descriptive and inferential analyses were performed using chi-squared tests, Student's t-tests, and a Poisson regression. The prevalence of DAO was 10.73%. In the preliminary bivariate analysis, the variables of age range, marital status, number of diseases, functional disability for basic and instrumental activities of daily living, gait speed, and level of physical activity met the established criterion. The final model indicated that only gait speed was a predictor of DAO in older adults. DAO affects nearly 11% of community-dwelling older adults from northern Brazil; gait speed was a predictor of DAO and could be a useful tool for managing and monitoring this population's health.

Resumo O objetivo deste artigo é identificar a prevalência e os fatores associados à obesidade abdominal dinapênica (OAD) em idosos de uma cidade da região Norte do Brasil. Estudo transversal realizado com 382 idosos comunitários residentes em Macapá, Amapá, Brasil. As informações socioeconômicas, clínicas e de saúde foram coletadas por meio de um formulário estruturado. A OAD foi definida pela combinação de dinapenia (força de preensão manual < 26 kgf para homens e < 16 kgf para mulheres) e obesidade abdominal (circunferência abdominal > 102 cm para homens e > 88 cm para mulheres). As análises descritivas e inferenciais foram realizadas utilizando os testes qui-quadrado, t de Student e regressão de Poisson. A prevalência de OAD foi de 10,73%. Na análise bivariada preliminar, as variáveis faixa etária, estado conjugal, número de doenças, incapacidade funcional para atividades básicas e instrumentais de vida diária, velocidade da marcha e nível de atividade física atenderam ao critério estabelecido. O modelo final indicou que apenas a velocidade da marcha foi um preditor para a OAD em idosos. A OAD afeta quase 11% dos idosos residentes nessa comunidade do Norte do Brasil; e a velocidade de marcha é um preditor que pode ser uma ferramenta útil para gerenciar e monitorar a saúde desta população.

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RESUMEN Objetivo. Identificar los mecanismos reportados en intervenciones de atención primaria en salud (APS) en poblaciones rurales y urbanas marginales entre los años 1997 y 2019. Métodos. Se utilizó el método de revisión sistemática exploratoria para identificar la literatura. La búsqueda de literatura fue realizada en las bases de datos Medline (Pubmed y Ovid), Global health, Embase, Web of science, Scopus y Lilacs. La inclusión de literatura consideró estudios de intervención primaria, observacionales con metodologías cualitativas, cuantitativas o mixtas. Se incluyeron artículos en inglés, portugués y español publicados entre 1997 y 2019. Para la selección de documentos definitivos se utilizó Rayyan QCRI, se excluyeron fuentes de información de literatura gris o investigación en progreso. Resultados. A nivel individual se identificaron tres grupos de mecanismos: niveles de relaciones entre las intervenciones y los sujetos, transformaciones que pueden generar en los individuos y las relaciones recíprocas. A nivel institucional se relacionaron con la temporalidad, el dinero, relaciones de poder, relaciones de confianza, el sistema de salud, las expectativas y las condiciones administrativas. Conclusiones. Los mecanismos individuales son similares en los diferentes contextos, los mecanismos institucionales son susceptibles a la variación del contexto, se representan en la temporalidad, recursos económicos, relaciones de poder y de confianza, el sistema de salud, las expectativas y condiciones administrativas.

ABSTRACT Objective. Identify mechanisms reported in primary health care (PHC) interventions in rural and marginal urban populations from 1997 to 2019. Methods. A scoping review was used to identify the literature. The literature search was conducted using the Medline (PubMed and Ovid), Global Health, Embase, Web of Science, Scopus, and Lilacs databases. Inclusion criteria considered literature on primary intervention and observational studies using qualitative, quantitative, or mixed methods. Articles in English, Portuguese, and Spanish published from 1997 to 2019 were included. Rayyan QCRI was used for definitive document selection; sources of information from gray literature or research in progress were excluded. Results. At the individual level, three groups of mechanisms were identified: levels of relationships between interventions and subjects, transformations that can occur in individuals, and reciprocal relationships. At the institutional level, mechanisms were related to temporality, money, power relations, trust relations, the health system, expectations, and administrative conditions. Conclusions. Individual mechanisms are similar in different contexts. Institutional mechanisms are susceptible to variations in context and are expressed in terms of temporality, economic resources, power and trust relations, the health system, expectations, and administrative conditions.

RESUMO Objetivo. Identificar os mecanismos relatados nas intervenções de atenção primária à saúde (APS) em populações rurais e urbanas periféricas entre 1997 e 2019. Métodos. Foi utilizado o método de revisão sistemática exploratória para identificar a literatura. A busca bibliográfica foi feita nas bases de dados Medline (Pubmed e Ovid), Global Health, Embase, Web of Science, Scopus e Lilacs. A inclusão da literatura considerou estudos de intervenção primária, observacionais, com metodologias qualitativas, quantitativas ou mistas. Foram incluídos artigos em inglês, português e espanhol publicados entre 1997 e 2019. Para a seleção dos documentos definitivos foi utilizado o Rayyan QCRI e foram excluídas fontes de informação da literatura cinzenta ou de pesquisas em andamento. Resultados. No nível individual, foram identificados três grupos de mecanismos: níveis de relações entre as intervenções e os sujeitos, transformações que podem ocorrer nos indivíduos e relações recíprocas. No nível institucional, se relacionaram a temporalidade, dinheiro, relações de poder, relações de confiança, sistema de saúde, expectativas e condições administrativas. Conclusões. Os mecanismos individuais são semelhantes nos diferentes contextos. Os mecanismos institucionais são suscetíveis à variação do contexto e estão representados na temporalidade, nos recursos econômicos, nas relações de poder e confiança, no sistema de saúde, nas expectativas e nas condições administrativas.

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RESUMEN Introducción: una de las estrategias que se consideraron a la hora de hacer frente a los problemas de salud mental durante la pandemia de COVID-19 fue la utilización de la telepsiquiatría. Objetivo: determinar si la procedencia urbana o rural se asocia al desarrollo de trastornos depresivos en pacientes que consultan a través de telepsiquiatría en un Hospital de referencia de Paraguay. Metodología: estudio observacional, descriptivo de asociación cruzada, de corte transversal. Se realizó un muestreo no probabilístico, de casos consecutivos. Se utilizaron fichas electrónicas de pacientes tratados en el Servicio de Psiquiatría del Hospital de Clínicas de la Universidad Nacional de Asunción entre marzo y junio de 2021. Se aplicó estadística descriptiva para todas las variables. Para la comparación de grupos con variables cualitativas nominales se utilizó la prueba de Chi cuadrado, calculando el odds ratio según sexo y área de residencia, considerando una p˂0,05 como significativa. Se utilizó, además, la prueba T de Student para comparar una variable nominal con una variable cuantitativa. Resultados: se analizaron 907 fichas clínicas, encontrándose 92 pacientes con trastornos del espectro depresivo. Al analizar la asociación entre el ambiente rural y urbano con la presencia de un episodio depresivo, se encontró una asociación significativa entre el ambiente rural y el diagnóstico de un trastorno depresivo (OR=7,81, χ2=63,33, p<0,001). Conclusión: nuestros resultados no condicen con estudios previos relacionados al tema. Esto podría deberse, al menos en parte, al impacto que las condiciones sociales y económicas tienen en el desarrollo de trastornos mentales, como la depresión.

ABSTRACT Introduction: one of the strategies considered when dealing with mental health problems during the COVID-19 pandemic was the use of telepsychiatry. Objective: to determine whether urban or rural origin is associated with the development of depressive disorders in patients consulting through telepsychiatry in a referral hospital in Paraguay. Methodology: observational, descriptive of cross-association, and cross-sectional study. A non-probabilistic sampling of consecutive cases was carried out. Electronic records of patients treated at the Psychiatry Service of the "Hospital de Clínicas" of the "Universidad Nacional de Asunción" between March and June 2021 were used. Descriptive statistics were applied for all variables. For the comparison of groups with nominal qualitative variables, the Chi-square test was used, calculating the odds ratio according to sex and area of residence, considering a p˂0.05 as significant. Student's t-test was also used to compare a nominal variable with a quantitative variable. Results: 907 clinical records were analyzed, finding 92 patients with depressive spectrum disorders. When analyzing the association between rural and urban environment with the presence of a depressive episode, a significant association was found between rural environment and the diagnosis of a depressive disorder (OR=7.81, χ2=63.33, p<0.001). Conclusion: our results do not agree with previous studies related to the subject. This could be due, at least in part, to the impact that social and economic conditions have on the development of mental disorders, such as depression.

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Among the social effects of the COVID-19 pandemic, increased poverty, unemployment, and social inequality in Brazil have led to worsening health problems, especially in the poorest citizens. The purpose of this research was to discuss the potentialities and limitations of the work process in primary health care based on the Family Health Strategy. In order to do so, we conducted semi-structured interviews with four women living in an informal settlement in the interior of the state of São Paulo, Brazil, between January and February 2020. We found that the women experienced suffering in relation to issues such as housing precariousness, transience, social isolation, and silencing. The way in which primary health care is organized and professionals' work processes make it difficult for this population to access health services and for professionals to perceive their suffering. The findings of this research point to the need to reevaluate and improve the Family Health Strategy.

Entre los efectos sociales de la pandemia de COVID-19, el aumento de la pobreza, el desempleo y la desigualdad social en el país agravaron los problemas de salud, principalmente, de la población más pobre. Esta investigación buscó discutir potencialidades y limitaciones del proceso de trabajo en atención primaria de la salud, basado en la Estrategia de Salud Familiar. Para ello, entre enero y febrero de 2020, se realizaron entrevistas semiestructuradas a cuatro mujeres residentes de una ocupación urbana del interior del estado de São Paulo, Brasil. Se encontró que presentan sufrimiento relacionado con la precariedad de las viviendas, la provisoriedad, el aislamiento social y el silenciamiento. El modo en que se organiza la atención primaria de la salud y el proceso de trabajo de las y los profesionales dificulta tanto el acceso de una parte de la población a los servicios de salud, como la percepción de las y los profesionales sobre el sufrimiento de la población. Los resultados de la investigación indican la necesidad de una nueva evaluación y perfeccionamiento de la Estrategia de Salud Familiar.

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RESUMEN Introducción: los trastornos alimentarios y de la ingestión de alimentos están asociados con importantes efectos físicos y morbilidad psicosocial, así como con un impacto negativo en la calidad de vida de las personas. Objetivo: determinar la proporción de pacientes con riesgo de padecer algún trastorno alimentario y de la ingestión de alimentos en población general paraguaya. Metodología: estudio observacional, descriptivo de asociación cruzada, de corte transversal y temporalmente prospectivo. Una encuesta en línea fue difundida a nivel nacional a través de redes sociales (Facebook, Twitter, Instagram) y aplicaciones de mensajería (Whatsapp, Telegram). Se recabaron datos sociodemográficos y los participantes respondieron la Eating Disorder Examination Questionnaire (S-EDE-Q), en búsqueda de trastornos alimentarios. Se utilizó estadística descriptiva para todas las variables. Para buscar asociaciones se utilizaron la prueba t de Student y ANOVA, según sea apropiado. Para cuantificar los riesgos se utilizó Odds ratio. Resultados: participaron 375 personas, de las cuales el 70,9 % era del sexo femenino, con edad media de 31 ± 9 años. Se obtuvo una media de 2,09 ± 1,5 puntos en la Eating Disorder Examination Questionnaire (S-EDE-Q) y se encontró que 51 participantes tenían indicios de padecer algún tipo de trastorno alimentario. Conclusión: el 13,6 % de los participantes de esta investigación tiene indicios de padecer algún tipo de trastorno alimentario, las mujeres tienen 2,4 veces más chances de padecer un trastorno y existen una serie de factores que están asociados a un mayor riesgo en el desarrollo de algún tipo de trastorno alimentario.

ABSTRACT Introduction: feeding and eating disorders are associated with significant physical effects and psychosocial morbidity, as well as a negative impact on people's quality of life. Objective: to determine the proportion of patients at risk of suffering from a feeding and eating disorder in the general Paraguayan population. Methodology: observational, descriptive, cross-sectional study, of cross-association and temporally prospective. An online survey was disseminated nationwide through social media (Facebook, Twitter, Instagram) and messaging applications apps (WhatsApp, Telegram). Sociodemographic data were collected and the participants answered the Eating Disorder Examination Questionnaire (S-EDE-Q), in search of eating disorders. Descriptive statistics were used for all variables. Student's t test and ANOVA were used to look for associations, as appropriate. Odds ratio was used to quantify the risks. Results: 375 people participated, of which 70,9 % were female, with a mean age of 31 ± 9 years. A mean of 2,09 ± 1.5 points was obtained on the Eating Disorder Examination Questionnaire (S-EDE-Q) and it was found that 51 participants had signs of suffering from some type of eating disorder. Conclusion: 13,6 % of the participants in this research have signs of suffering from some type of eating disorder, women are 2.4 times more likely to suffer from an eating disorder and there are a series of factors that are associated with a greater risk for the development of some type of eating disorder.

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A pandemia pelo Sars-CoV2 impôs uma necessidade de reorganização do processo de trabalho das equipes de Saúde da Família, resultando em desafios ao acesso, ao manejo de condições crônicas e ao acompanhamento e monitoramento de pessoas infectadas pelo coronavírus. Este artigo descreve os usos e desafios das tecnologias chamada telefônica e WhatsApp Business em uma equipe de uma Clínica da Família em uma favela do Rio de Janeiro. Pode-se dizer que o uso foi uma experiência importante para conseguir ampliar o acesso e fortalecer vínculo, principalmente a pessoas vivendo com condições crônicas não transmissíveis e de saúde mental no cenário de restrição de acesso imposto pelo contexto da pandemia pelo Sars-CoV2.

The Sars-CoV2 pandemic imposed a need to reorganize the work process of the Family Health teams resulting in challenges to access, management of chronic conditions and monitoring of people infected with the coronavirus. This article describes the uses and challenges of technologies like telephone calls and Whatsapp business in a Family Clinic team in a Rio de Janeiro slum. It's possible to say that this use was an important experience to expand access and strengthen bonds, especially to people living with non-transmissible chronic and mental health conditions in a scenario of restricted access due to the context of the Sars-CoV2 pandemic.

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