RESUMO
AIM: To evaluate the microbial colonization in different dentition phases on individuals from 0 to 18 years of age belonging to families with a history of periodontitis compared to descendants of periodontally healthy parents. MATERIALS AND METHODS: The offspring of subjects with periodontitis ('Perio' group) and the offspring of periodontally healthy subjects ('Healthy' group), matched for gender and age, were included in this cross-sectional study and divided according to the dentition phase: pre-dentate, primary, mixed and permanent. The patients were clinically assessed, and their saliva was collected. DNA was extracted, and V1-V3 and V4-V5 regions of the 16S rRNA gene were sequenced. RESULTS: Fifty children of parents with periodontitis and 50 from healthy parents were included in the study and divided according to the dentition phase: pre-dentate (n = 5/group), primary dentition (n = 15/group), mixed dentition (n = 15/group) and permanent dentition (n = 15/group) in each group. The microbiome composition was different between dentitions for both groups. Children of the Perio group presented a microbial diversity different from that of the Healthy group in mixed and permanent dentitions. The more intense shift in the community occurred between primary and mixed dentition in the Perio group, while the transition between mixed and permanent dentition was the period with greater changes in the microbiome for the Healthy group. Furthermore, a pathogen-rich environment-higher prevalence and abundance of periodontitis-associated species such as Prevotella spp., Selenomonas spp., Leptotrichia spp., Filifactor alocis, Prevotella intermedia, Treponema denticola and Tannerella forsythia- was observed in the Perio group. CONCLUSIONS: The parents' periodontal status significantly affects the microbiome composition of their offspring from an early age. The mixed dentition was the phase associated with establishing a dysbiotic and pathogen-rich microbiome in descendants of parents with periodontitis.
Assuntos
Microbiota , Periodontite , Criança , Humanos , RNA Ribossômico 16S/genética , Estudos Transversais , Microbiota/genética , Pais , DisbioseRESUMO
Se realizó un estudio epidemiológico descriptivo transversal de la dentición permanente en la provincia de Santa Clara desde el año 2005 al año 2009, con el objetivo de determinar el orden de emergencia de la dentición permanente. El universo fue de 45 724 infantes de ambos sexos entre los 4 y 14 años de edad. La muestra fue de 1 769 individuos. Se hallaron los percentiles de emergencia y a partir del percentil 50 se estableció el orden. Se compararon los dientes para cada grupo eruptivo y se estudió la simetría. Se estableció el orden de emergencia. Hubo diferencias para el orden entre los sexos, hemiarcadas y con las tablas de otros autores. Los dientes más simétricos fueron los incisivos y los primeros molares. Se concluyó que no siempre los dientes inferiores brotaron antes que sus homólogos superiores, los incisivos y primeros molares son los más simétricos en el brote. El primer diente permanente en emerger fue el incisivo central inferior o el primer molar inferior. Lo más frecuente fue que los caninos superiores e inferiores brotaran después que las primeras bicúspides(AU)
A cross-sectional, descriptive and epidemiologic study was conducted of the permanent dentition of children from Santa Clara municipality from 2005 to 2009 to determine the emergence order of permanent dentition. Universe included 45 724 infants of both sexes aged between 4 and 14. Sample included 1 769 subjects. There were emergence percentiles and from the 50 percentile the order was established. The teeth for each eruptive group were compared and symmetry was studied, establishing the emergence order. There were order differences between both sexes, hemiarcades and with the tables from other authors. The more symmetric teeth were the incisives and the first molars. We conclude that not always the lower teeth erupt before the upper ones, the incisives and first molars are the more symmetric in eruption. The first erupted permanent tooth may be the lower central incisive or the first lower molar. The more frequent situation is that the upper and lower canines erupt after the first bicuspids(AU)
Assuntos
Humanos , Masculino , Feminino , Criança , Arco Dental/fisiologia , Dentição Permanente , Erupção Dentária , Epidemiologia Descritiva , Estudos TransversaisRESUMO
Se realizó un estudio epidemiológico descriptivo transversal en Santa Clara desde el año 2005 al año 2009, con el objetivo de determinar la cronología de emergencia de la dentición permanente en niños y niñas del municipio Santa Clara y establecer las diferencias con relación a los valores ofrecidos para otras poblaciones. El universo fue de 45 724 infantes de ambos sexos entre los 4 y los 14 años de edad, con una muestra de 1 769 individuos. Se obtuvieron los valores medios y se estableció la cronología a partir del 50 percentil. Se compararon los promedios de erupción obtenidos con los ofrecidos por otros autores. Se determinó la edad de emergencia de los dientes permanentes en la muestra estudiada. Hubo adelanto cronológico en: incisivos, caninos superiores, primeros molares inferiores y segundos bicúspides inferiores, retardo para segundos bicúspides superiores y caninos inferiores en relación con los autores seleccionados para la comparación. La cronología de emergencia obtenida difiere de los valores ofrecidos para otras poblaciones. La mayor coincidencia resultó con valores de Logan y Kronfeld. La cronología de emergencia difiere entre los sexos(AU)
A cross-sectional, descriptive and epidemiologic study was conducted of permanent dentition of children from Santa Clara municipality between 2005 and 2009. To determine the permanent dentition emergence chronology in children (boys and girls) from the Santa Clara municipality and to establish the differences in relation to values offered by other populations. The universe included 45 724 infants of both sexes aged between 4 and 14 with a sample of 1 769 subjects. Mean values were obtained establishing the chronology from the 50 percentile comparing the obtained eruption averages with that offered by other authors. The age of permanent teeth emergence was determined in study sample. There was a chronologic advance in: incisors, upper canines, first lower molars and second lower bicuspids, and retard for the second upper bicuspids and the canines in relation to authors selected for comparison. The emergence chronology achieved differs from the values offered by other populations. The great coincidence was in the case of Logan and Kronfeld values. The above chronology differs between sexes(AU)
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Arco Dental , Dentição Permanente , Erupção Dentária , Epidemiologia Descritiva , Estudos TransversaisRESUMO
Squirrel monkeys, colony-born from Bolivian parents, were studied to establish the sequences and timing of eruption for deciduous and permanent teeth. Infants were born with a naked gingiva, and in only one monkey was di1 present at birth. The eruption of the lower deciduous teeth preceded their upper counterparts with the exception of di2, dc, and dpm2. No significant differences were found between the right and left quadrants of the mandible and maxilla. No significant sexual differences were found in the age of eruption. By the age of 14 weeks, all deciduous teeth had erupted. The sequence of eruption of the replacement teeth was different from that of milk teeth. The differences lie in the delayed eruption of canine teeth and in the inverted sequence, from the back to the front, of the premolar series. Significant sexual differences were found in total eruption (TE) for PM3 and I2 (P < 0.05) and highly significant differences (P < 0.01) in TE and initial eruption (IE) for C1, females being more precocious than males. The age at which monkeys completed dental eruption was highly variable, 103-119 weeks for males and 89-112 weeks for females. Differences were found when our results were compared with those of Long and Cooper [1968] for Colombian squirrel monkeys.