RESUMO
We describe the case of a 50-year-old woman with a history of SLE and APS that presented with a spontaneous subdural haematoma, prolonged aPTT, PT and INR and positive LA. The activity of the coagulation factors II, VIII, IX and XI was extremely low, and anti-prothrombin antibody IgG was positive. LAHS was established, with inhibition of the intrinsic pathway, as an acquired haemophilia. The patient received corticosteroids and cyclophosphamide as treatment. To the best of our knowledge, this is one of the few reports of spontaneous intracranial bleeding, an unusual and initial manifestation of LAHS in an adult patient.HighlightsLAHS is characterised by the presence of LA and hypoprothrombinaemia caused by anti-prothrombin antibodies.Prolonged aPTT and INR, and positive LA are important laboratory findings that help the suspicion of LAHS.Intracranial bleeding is an unusual manifestation of LAHS associated with low factor II activity.Corticosteroids are the first-line treatment of LAHS.The prognosis of LAHS is good with adequate treatment, with a reported mortality of 5%.
Assuntos
Síndrome Antifosfolipídica , Hipoprotrombinemias , Síndrome Antifosfolipídica/diagnóstico , Feminino , Hematoma Subdural/etiologia , Humanos , Hipoprotrombinemias/diagnóstico , Inibidor de Coagulação do Lúpus , Pessoa de Meia-IdadeRESUMO
Introducción: Las complicaciones intracraneanas de la otomastoiditis crónica supurada (OMCS) se ven cada vez con menor frecuencia gracias al diagnóstico precoz, acceso a imagenología y uso de antibióticos. La asociación de una OMCS con empiema extradural y hematoma subdural crónico es extremadamente infrecuente y y reportar un caso clinico es el objetivo de este reporte. Caso clínico: Paciente de 28 años, con historia de trauma craneano dos meses antes del ingreso. Consultó por otorrea fétida derecha de 45 días de evolución. Un mes previo a la consulta instala tumoración fluctuante en planos superficiales de región temporoparietal derecha que aumenta de tamaño y se hace dolorosa. Examen neurológico normal. Se realiza tomografía de cráneo que evidencia colección extradural y subdural, asociada a otomastoiditis. Se intervino en conjunto con ORL para evacuación del proceso supurado intracraneano y mastoidectomía, encontrándose en el intraoperatorio que la colección subdural no era infecciosa (empiema), sino que era un hematoma subdural crónico. La evolución fue buena siendo dado de alta asintomático. Reportamos esta asociación lesional muy poco frecuente, cuyo diagnóstico preoperatorio hubiera hecho variar la táctica neuroquirúrgica. Se discuten los hechos clínicos e imagenológicos que podrían haber llevado al diagnóstico correcto.
Introduction: Intracranial complications of chronic suppurative otomastoiditis (OMCS) are seen less and less frequently seen thanks to early diagnosis, access to imaging and access to antibiotics. The association of an OMCS with extradural empyema and chronic subdural hematoma is extremely infrequent. We report a clincal case of OMCS associated with a chronic subdural haematoma. Clinical case: A 28-year-old patient with a history of cranial trauma two months before admission, who consulted for a 46-day history of fetid otorrhea. One month prior to the consultation, he detected a fluctuating tumor in superficial planes of the right temporoparietal region that increased and became painful. He has a normal neurological examination. We performed a cranial CT and we detected an extradural and subdural collection, associated with otomastoiditis. A surgical intervention with a combined team was performed (Othologist and neurosurgeons). The aim of the surgery to evacuate the intracranial process and mastoidectomy. In the intraoperative period, we discovered that the subdural collection was not infectious but a chronic subdural hematoma. The evolution was good being discharged asymptomatic. We report a very rare association (OMCS with chronic subdural haematoma), whose preoperative diagnosis would have changed the neurosurgical tactic. Clinical and imaging facts that could have led to the correct diagnosis are discussed.
Assuntos
Otite Média Supurativa , Hematoma Subdural Crônico , EmpiemaRESUMO
ABSTRACTBACKGROUND AND OBJECTIVES: Only few reports in literature have pointed out to the possibility of a cranial subdural haematoma formation associated with dural puncture during spinal or epidural analgesia. We herein describe such a rare case who was diagnosed to have acute subdural haematoma after combined spinal-epidural anaesthesia used in labour.CASE REPORT: A 34-year-old, primigravid women with a gestation of 38 weeks underwent caesarean section under combined spinal-epidural anaesthesia and gave birth to a healthy boy. Thirty-two hours after delivery, her moderate headache progressed to a severe headache associated with nausea and vomiting and later was more complicated with a generalized tonic-clonic seizure and ensuing lethargy. Computed tomography of the brain demonstrated a right-sided fronto-temporo-parietal acute subdural haematoma with diffuse cerebral oedema. She underwent urgent FTP craniotomy and evacuation of the haematoma. Early postoperative cranial computed tomography showed a clean operative site. Eight days after subdural haematoma surgery, she became lethargic again, and this time cranial computed tomography disclosed an extradural haematoma under the bone flap for which she had to undergo surgery again. Two days later, she was discharged home with Karnofsky performance score of 90/100. At follow-up exam, she was neurologically intact and her cranial computed tomography and magnetic resonance were normal.CONCLUSIONS: As conclusion, with the use of this combined spinal-epidural anaesthesia, it should be kept in mind that headache does not always mean low pressure headache associated with spinal anaesthesia and that a catastrophic complication of subdural haematoma may also occur.
RESUMOJUSTIFICATIVA E OBJETIVOS: Apenas alguns relatos na literatura mencionaram a possibilidade de formação de hematoma subdural craniano associada à punção durante a raquianestesia ou anestesia epidural. O presente relato descreve um caso tão raro que foi diagnosticado como hematoma subdural agudo após anestesia combinada raqui-peridural usada em parto.RELATO DE CASO: Paciente primípara, 34 anos, com 38 semanas de gestação, submetida à cesariana sob anestesia combinada raqui-peridural, deu à luz um menino saudável. Após 32 horas do parto, a dor de cabeça moderada da paciente progrediu para dor de cabeça intensa associada a náusea e vômito e se complicou subsequentemente com crise convulsiva generalizada tônico-clônica e consequente letargia. Tomografia computadorizada do cérebro revelou hematoma subdural agudo do lado direito em região frontotemporoparietal (FTP) com edema cerebral difuso. A paciente foi submetida à craniotomia FTP de urgência e evacuação do hematoma. Tomografia computadorizada do crânio no pós-operatório precoce mostrou um sítio operatório limpo. Oito dias após a cirurgia do hematoma subdural, a paciente voltou a ficar letárgica e, dessa vez, a tomografia computadorizada revelou um hematoma extradural sob o retalho ósseo que exigiu outra cirurgia. Dois dias depois, a paciente recebeu alta hospitalar com classificação de desempenho Karnofsky de 90/100. Ao exame de acompanhamento, a paciente apresentou-se neurologicamente intacta e sua tomografia computadorizada e ressonância magnética estavam normais.CONCLUSÃO: Ao usar a anestesia combinada raqui-peridural deve-se ter em mente que dor de cabeça nem sempre significa dor de cabeça hipotensiva associada à raquianestesia e que uma complicação catastrófica de hematoma subdural também pode ocorrer.
Assuntos
Humanos , Feminino , Gravidez , Adulto , Hematoma Subdural Agudo/etiologia , Anestesia Epidural/efeitos adversos , Anestesia Obstétrica/efeitos adversos , Raquianestesia/efeitos adversos , Hematoma Subdural Agudo/diagnóstico por imagemRESUMO
BACKGROUND AND OBJECTIVES: Only few reports in literature have pointed out to the possibility of a cranial subdural haematoma formation associated with dural puncture during spinal orepidural analgesia. We herein describe such a rare case who was diagnosed to have acute subdural haematoma after combined spinal-epidural anaesthesia used in labour. CASE REPORT: A 34-year-old, primigravid women with a gestation of 38 weeks underwent cae-sarean section under combined spinal-epidural anaesthesia and gave birth to a healthy boy. Thirty-two hours after delivery, her moderate headache progressed to a severe headache associated with nausea and vomiting and later was more complicated with a generalized tonic-clonic seizure and ensuing lethargy. Computed tomography of the brain demonstrated a right-sided fronto-temporo-parietal acute subdural haematoma with diffuse cerebral oedema. She under-went urgent FTP craniotomy and evacuation of the haematoma. Early postoperative cranial computed tomography showed a clean operative site. Eight days after subdural haematoma surgery, she became lethargic again, and this time cranial computed tomography disclosed anextradural haematoma under the bone flap for which she had to undergo surgery again. Two days later, she was discharged home with Karnofsky performance score of 90/100. At follow-up exam, she was neurologically intact and her cranial computed tomography and magnetic resonance were normal. CONCLUSIONS: As conclusion, with the use of this combined spinal-epidural anaesthesia, it should be kept in mind that headache does not always mean low pressure headache associated with spinal anaesthesia and that a catastrophic complication of subdural haematoma may also occur.
RESUMO
BACKGROUND AND OBJECTIVES: Only few reports in literature have pointed out to the possibility of a cranial subdural haematoma formation associated with dural puncture during spinal or epidural analgesia. We herein describe such a rare case who was diagnosed to have acute subdural haematoma after combined spinal-epidural anaesthesia used in labour. CASE REPORT: A 34-year-old, primigravid women with a gestation of 38 weeks underwent caesarean section under combined spinal-epidural anaesthesia and gave birth to a healthy boy. Thirty-two hours after delivery, her moderate headache progressed to a severe headache associated with nausea and vomiting and later was more complicated with a generalized tonic-clonic seizure and ensuing lethargy. Computed tomography of the brain demonstrated a right-sided fronto-temporo-parietal acute subdural haematoma with diffuse cerebral oedema. She underwent urgent FTP craniotomy and evacuation of the haematoma. Early postoperative cranial computed tomography showed a clean operative site. Eight days after subdural haematoma surgery, she became lethargic again, and this time cranial computed tomography disclosed an extradural haematoma under the bone flap for which she had to undergo surgery again. Two days later, she was discharged home with Karnofsky performance score of 90/100. At follow-up exam, she was neurologically intact and her cranial computed tomography and magnetic resonance were normal. CONCLUSIONS: As conclusion, with the use of this combined spinal-epidural anaesthesia, it should be kept in mind that headache does not always mean low pressure headache associated with spinal anaesthesia and that a catastrophic complication of subdural haematoma may also occur.
Assuntos
Anestesia Epidural/efeitos adversos , Anestesia Obstétrica/efeitos adversos , Raquianestesia/efeitos adversos , Hematoma Subdural Agudo/etiologia , Adulto , Feminino , Hematoma Subdural Agudo/diagnóstico por imagem , Humanos , GravidezRESUMO
El síndrome del niño sacudido (SNS) es una forma de abuso físico caracterizada por ciertos hallazgos clínicos entre los que se encuentran presencia de hematoma subdural o subaracnoideo, edema cerebral difuso, y hemorragias retinianas, en ausencia de otras muestras físicas de lesión traumática, los cuales se producen al sacudir fuertemente al niño tomado del tórax o las extremidades. La aceleración-desaceleracion producida por dicho movimiento constituye el mecanismo de lesión. El cuadro clínico se puede manifestar con hallazgos inespecíficos como vómitos, somnolencia, irritabilidad hasta signos como los mencionados anteriormente, estos niños suelen presentar secuelas a corto y largo plazo. En Costa Rica la legislación ampara al menor contra los maltratos y da al sistema de salud la labor de salvaguardar la integridad y vida del mismo.
The shaken baby syndrome (SBS) is a form of physical abuse characterized for some clinical findings including the presence of a subdural or subarachnoid haematoma, diffuse cerebral edema and retinal haemorrhages and absence of other physical signs of traumatic injury which are produced when the victim is held by the torso or the extremities and violently shaken. The acceleration - deceleration produced by the movement is thought to be the production mechanism of the injury. The clinical findings could be as unspecific as vomits, sleepiness, irritability or signs like the ones listed above, this children often presents short and long term complications. In Costa Rica the legislation protects the children against abuses and give the health system the responsibility of taking care of childrens integrity and life.
Assuntos
Humanos , Masculino , Feminino , Criança , Maus-Tratos Infantis , Hematoma Subdural , Hemorragia Retiniana , Síndrome do Bebê SacudidoRESUMO
El hematoma subdural crónico constituye una entidad nosológica frecuente en la práctica neuroquirúrgica, existiendo múltiples modalidades de tratamiento propuestas con resultados muy diversos. Se hizo una revisión de varios de los aspectos del tratamiento de estos pacientes para intentar formular recomendaciones generales de manejo de acuerdo a los trabajos científicos publicados y a la experiencia de los autores. Se plantea un tratamiento basado en la fisiopatología del hematoma subdural crónico y su correspondiente traducción imagenológica.
Chronic Subdural Haematoma is a frequent neurosurgical condition,with multple treatment modalities and diverse results. The authors have made a review of various aspects of treatmentin these patients aiming to establish general recommendations, based on the scientific publications and their own experience. The proposed treatment is based on the physiopatology of theChronic Subdural Haematoma and the images pattern.
Assuntos
Drenagem , Hematoma Subdural Crônico , Procedimentos Cirúrgicos OperatóriosRESUMO
El hematoma subdural crónico constituye una entidad nosológica frecuente en la práctica neuroquirúrgica, existiendo múltiples modalidades de tratamiento propuestas con resultados muy diversos. Se hizo una revisión de varios de los aspectos del tratamiento de estos pacientes para intentar formular recomendaciones generales de manejo de acuerdo a los trabajos científicos publicados y a la experiencia de los autores. Se plantea un tratamiento basado en la fisiopatología del hematoma subdural crónico y su correspondiente traducción imagenológica.(AU)
Chronic Subdural Haematoma is a frequent neurosurgical condition,with multple treatment modalities and diverse results. The authors have made a review of various aspects of treatmentin these patients aiming to establish general recommendations, based on the scientific publications and their own experience. The proposed treatment is based on the physiopatology of theChronic Subdural Haematoma and the images pattern.(AU)
Assuntos
Hematoma Subdural Crônico , Drenagem , Procedimentos Cirúrgicos OperatóriosRESUMO
El síndrome del niño sacudido es una de las formas más severas de maltrato infantil que ocurre principalmente en niños menores de un año. Por la vulnerabilidad de las víctimas y por las secuelas que puede producir, incluyendo la muerte, es necesario, en el abordaje clínico, tener presente la sospecha diagnóstica ante lesiones de explicación insatisfactoria por parte de los encargados del menor. Asimismo si se trata de un abordaje médico legal deben tenerse las consideraciones necesarias para documentar las lesiones, tanto en el paciente vivo, como en los casos de homicidio, para colaborar con la administración de justicia. Para ello se debe tratar de implementar una metodología homogénea para la realización de dichas pericias, tanto en la parte clínica como patológico forense. En este artículo se describe la forma habitual de presentación clínica del síndrome del niño sacudido y se expone una guía básica para la realización de autopsias medico legales en casos de muertes por esta causa.
The shaken baby syndrome is one of the most severe presentations of child abuse that is seen in children especially under the first year of age. The great vulnerability of this group of patients and the serious consequences that they may encounter in the future, including death, are enough reason to inquire, during the clinical approach, about the possibility that the patient being attended may be a victim of physical abuse. From a medico-legal evaluation, it is pertinent to document and describe thoroughly the physical lesions in the living patient and in cases of homicide, in order to contribute scientifically in the administration of justice. For that reason it is essential to follow a uniform methodology in the management of both the clinical and the forensic assessment. This article reviews the usual clinical presentation of the shaken baby syndrome and proposes a basic guide to evaluate the autopsies in cases of deaths originated by this cause.