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New Phytol ; 233(3): 1074-1082, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34705271

RESUMO

Oomycete phytopathogens have adapted to colonise plants using effectors as their molecular weapons. Intracellular effectors, mostly proteins but also small ribonucleic acids, are delivered by the pathogens into the host cell cytoplasm where they interfere with normal plant physiology. The diverse host processes emerging as 'victims' of these 'specialised bullets' include gene transcription and RNA-mediated silencing, cell death, protein stability, protein secretion and autophagy. Some effector targets are directly involved in defence execution, while others participate in fundamental metabolisms whose alteration collaterally affects defences. Other effector targets are susceptibility factors (SFs), that is host components that make plants vulnerable to pathogens. SFs are mostly negative regulators of immunity, but some seem necessary to sustain or promote pathogen colonisation.


Assuntos
Interações Hospedeiro-Patógeno , Oomicetos , Interações Hospedeiro-Patógeno/fisiologia , Oomicetos/metabolismo , Doenças das Plantas , Imunidade Vegetal , Plantas/metabolismo , Transporte Proteico , Proteínas/metabolismo
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