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Hypoglycemia is the most common metabolic alteration in the clinical routine of newborn dogs, acting as a predictor of mortality in these patients. The neonatal dog shows hepatic insufficiency and homeostatic mechanisms not yet fully developed, with limited glycogen reserves and limited capacity to perform glycogenolysis and gluconeogenesis. These physiological particularities make newborn dogs particularly susceptible to hypoglycemia when of fasting, even for short periods. Several maternal and neonatal factors may be related to a higher risk of developing hypoglycemia in neonates. This paper reviews glycemic homeostasis, the pathophysiology of neonatal hypoglycemia, the main causes involved and the diagnostic and therapeutic approaches to this condition.

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The aim of this study was to compare the safety and clinical efficacy of epidural levobupivacaine combined with fentanyl or sufentanil for bitches undergoing elective cesarean-section and the impact of these anesthetic protocols on neonatal viability. The anesthetic protocol consisted of intramuscular morphine (0.2 mg/kg), followed by an intravenous bolus of propofol, in a dose sufficient to allowed the puncture of the lumbosacral space. The dogs were randomly allocated to receive 0.5 % levobupivacaine plus fentanyl (2.5 µg/kg; LF: n = 9) or sufentanil (1 µg/kg; LS; n = 11). Maternal cardiorespiratory parameters were monitored at specific time points during surgery. Intraoperative propofol supplementation was based on the presence of head and/or thoracic limb movements. Neonatal reflex responses and the Apgar score (range 0-10 points) were assessed at 5 and 60 minutes after birth. Puppy mortality rate was recorded until 24 hours after birth. Data were analyzed using two-way ANOVA, Tukey's test, Wilcoxon signed rank test, and Fisher's exact test (P < 0.05). Intraoperatively, maternal cardiorespiratory variables and propofol requirements were similar between groups, with no detection of anesthetic complications. The puppy reflex responses did not differ between groups at any time point. The medians (range) of Apgar scores were lower (P = 0.016) in the LF [5 (1-9)] at 5 minutes in comparison with LS [6 (2-9)], while no intergroup differences were recorded at 60 minutes [LF = 8 (2-10); LS = 9 (6-10]. The total mortality rate was 4.1 %. In the LS group, no puppies died, while in the LF 8 % of the puppies died in the first 24 hours after birth (P = 0.11). Epidural levobupivacaine combined with fentanyl or sufentanil provided minimal maternal and neonatal adverse effects, but neither protocol enabled the performance of a C-section in 100 % of the French and English bulldogs, without propofol supplementation.

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Neonatal mortality in dogs reaches up to 40%. Due to the high rates, promptly detecting the causes and preventing newborns from dying are extremely important. Vitality evaluation, blood parameters, and the degree of meconium staining on the skin are valuable resources in canine perinatology. In this study, 435 puppies from 85 bitches close to parturition were recruited and divided into four quartiles according to the puppy's birth weight: Q1 (127-200 g) n = 110 puppies, Q2 (201-269 g) n = 108 puppies, Q3 (270-388 g) n = 108 puppies, and Q4 (389-464 g) n = 109 puppies. This experimental article aimed to report the effect of birth weight on the blood profile variables, the vitality of newborn puppies, and the meconium staining degree, integrating these three aspects. It was concluded that the weight of newborns was correlated with the degree of meconium staining, presenting more cases of severe meconium staining in the puppies of the highest birth weight group. The weight of the newborns was correlated with a higher number of stillbirths and alterations in the blood variables, showing the most severe cases of metabolic acidosis, hypoxia, and hypoglycemia in the puppies of the Q4 quartile. On the contrary, no statistically significant correlations were found between the weight of newborns and vitality. Nevertheless, the analysis of the results showed that the most vigorous puppies were found at Q1; however, at minute 60 after birth (AB), all the puppies in the four quartiles standardized their vitality scores.

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Hypothermia, a factor associated with neonatal mortality, can occur immediately after birth as a protective mechanism to prevent hypoxic damage in neonates, or to reduce the metabolic rate to improve the chances of survival in the first hours of life. The heat interchange through the superficial temperature of animals can be evaluated with infrared thermography (IRT). However, to date, there is no information on thermal windows in puppies. This study aimed to evaluate, with the use of IRT, the microcirculatory alterations in 8 different thermal windows identified at 7 different times in 289 newborn puppies assigned to different groups. Three thermograms were taken from four zones of each puppy: the facial, frontal, right lateral, and left lateral regions. Newborn puppies were grouped in 4 quartiles according to their weight: Q1 (126−226 g) n = 73, Q2 (227−330 g) n = 72, Q3 (331−387 g) n = 74, and Q4 (388−452 g) n = 70. A total of 8 thermal windows were considered at 7 evaluation times from Wet at birth until 24 h after birth (AB). Two-way mixed ANOVA within and between subjects' design for each thermal window (eight models) was performed. Results revealed a positive correlation between the puppy's weight and its ability to achieve thermostability in all the evaluated thermal windows. Statistically significant differences (p < 0.0001) between the 4 quartiles (Q1, Q2, Q3, and Q4) were found. The lowest temperatures were recorded when the pups were still wet and the highest at 24 h AB. Thermal windows with the highest temperatures were abdominal (34.234 ± 0.056 °C), thoracic (33.705 ± 0.049 °C), nasal (30.671 ± 0.110 °C), and upper left palpebral (34.066 ± 0.052 °C), while the lowest were thoracic limb brachial biceps (27.534 ± 0.051 °C), thoracic limb elbow (27.141 ± 0.049 °C), thoracic limb metacarpal (27.024 ± 0.062 °C), and femoral pelvic limb (27.654 ± 0.055 °C). Assessing the thermal response in newborn puppies can help identify drastic temperature reductions or deficient thermoregulatory compensation during the first hours of life, preventing the consequences of hypothermia.

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The thermal stability of newborns is an essential parameter that can be recorded to evaluate neonatal care. Knowing the thermal windows to evaluate and maintain a constant temperature helps significantly reduce neonatal mortality. This study aimed to assess the superficial temperature alterations in the distinct thermal windows of puppies with mothers of diverse weights and their repercussions. We evaluated the superficial temperature using infrared thermography at eight thermal windows and seven different times: when wet due to the fetal fluid immediately after birth until 24 h of life in newborn puppies from bitches divided into four bodyweight groups. The results revealed a positive correlation between the dam's weight and the ability to achieve thermostability in the newborn puppies in all the evaluated thermal windows. The time effect showed the lowest temperatures when the puppies were still wet, a gradual increase, and the highest temperature at 24 h after birth. The thermal windows with the highest temperatures were abdominal, thoracic, nasal, and upper left palpebral, and those with the lowest were the thoracic limb brachial biceps, thoracic limb elbow, metacarpal, and femoral pelvic limb. A significant increase in the temperatures in the thermal windows of the abdominal, thoracic, and upper left palpebral immediately after ingesting colostrum was observed. The weight of the dams is an important factor that positively intervenes in the thermoregulatory capacity of the puppies, especially when newborns are dry and have been passed 24 h after birth.

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In canines, size at birth is determined by the dam's weight, which would probably affect the newborn's viability due to litter size and birth order. Fetal hypoxia causes distress and acidemia. Identifying physiological blood alterations in the puppy during the first minute of life through the blood gas exchange of the umbilical cord could determine the puppy's risk of suffering asphyxiation during labor. This study aimed to evaluate the effect of the birth order and dam's size during spontaneous labor and the alterations during the first minute of life. The results indicate that the dam's size and the birth order have considerable physiological and metabolic effects in the puppies, mainly in birth order 1 (BO1) in small-size dogs, while in the medium size, the last puppy presented more alterations, probably because of a prolonged whelping which could have fostered hypoxic processes and death. Likewise, with large-size dogs, intrapartum asphyxiation processes were registered during the first minute of life in any birth order.

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The neonatal period in dogs remains associated with high mortality rates. Sepsis is the main cause of neonatal losses during the first three weeks of life. Additionally, failure in the clinical assessment and early diagnosis of sick newborns is still common, leading to inadequate care, which contributes to a high mortality rate. Thus, the objective of this study was to describe the incidence of sepsis in canine newborns, the clinical aspects involved, the main isolated bacterial agents and mortality rates to facilitate clinicians' early recognition of this condition. Of the 152 litters and 762 neonates evaluated, 14.8% (113/762) had sepsis or septic shock, and the mortality rate among affected puppies was 25.6% (29/113). Among the puppies with sepsis that died, early mortality (0-2 days of age) occurred in 69% (20/29) of affected neonates, and late mortality (3-30 days of age) occurred in 31% (9/29) of affected neonates. Significant differences (p < 0.0001) in clinical parameters (heart and respiratory rates, blood glucose, body temperature, peripheral oxygen saturation and reflexes) were noted among healthy neonates and neonates with sepsis and septic shock. The main and most relevant clinical signs were apathy, a reduced sucking reflex, diarrhea, the neonatal triad, failure to gain weight, bradycardia, dyspnea, cyanotic mucous membranes, body erythema, reduced peripheral oxygen saturation, cyanosis and tissue necrosis in the extremities. The mother may have been the main source of infection for 87.6% (99/113) of neonates with sepsis. Most infections were transmitted during pregnancy (68%, 77/113) in cases of neonatal sepsis. The major source of infection for neonates was the uterus, followed by breast milk and maternal oropharyngeal secretions. The most frequently isolated bacterial agent was Escherichia coli, accounting for 25.6% (29/113) of sepsis cases. The morbidity and mortality of neonatal sepsis in dogs is high. The clinical evaluation and diagnosis of sepsis in neonates differ from those in adult animals. Thus, knowledge of the neonatal particularities of sepsis is essential for proper clinical management and greater survival of these patients.

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Ao nascimento, a assistência neonatal é essencial, visto que filhotes podem apresentar depressão clínica, bradicardia, apneia persistente ou desconforto respiratório devido à hipóxia, decorrente de uma asfixia prolongada no útero ou durante o parto, necessitando de intervenção imediata. A equipe de recepção ao neonato precisa estar treinada para os procedimentos de reanimação neonatal, que devem ser realizados com enfoque em prover calor ao recém-nascido e no suporte ventilatório e circulatório, mantendo as vias aéreas patentes e uma adequada perfusão tecidual. O conhecimento das características fisiológicas neonatais e das etapas a serem seguidas no protocolo de reanimação, são cruciais para o sucesso da intervenção e maior sobrevivência neonatal.(AU)

At birth, neonatal assistance is essential, since puppies may experience clinical depression, bradycardia, persistent apnea or respiratory discomfort due to hypoxia, resulting from prolonged asphyxia in the uterus or during delivery, requiring immediate intervention. The team needs to be trained in neonatal resuscitation procedures, which must be performed with a focus on providing heat to the newborn and on ventilatory and circulatory support, maintaining patent airways and adequate tissue perfusion. Knowledge of the neonatal physiological characteristics and the steps to be followed in the resuscitation protocol are crucial for the success of the intervention and greater neonatal survival.(AU)

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This study aims to determine the effect of the weight of bitches on liveborn and stillbirth puppies from eutocic births, and physiological blood alterations during the first minute postpartum. A total of 52 female dogs were evaluated and distributed in four categories: C1 (4.0-8.0 kg, n = 19), C2 (8.1-16.0 kg, n = 16), C3 (16.1-32.0 kg, n = 11), and C4 (32.1-35.8 kg, n = 6). The dams produced 225 liveborn puppies and 47 were classified as stillbirth type II. Blood samples were taken from the umbilical vein to evaluate the concentration of gases, glucose, lactate, calcium, hematocrit levels, and blood pH. The liveborn puppies in C2, C3, and C4 had more evident physiological alterations (hypercapnia, acidosis) than those in C1 (p < 0.05). These signs indicate a process of transitory asphyxiation. The stillborn pups in all four categories had higher weights than their liveborn littermates. C3 and C4 had the highest mean weights (419.86 and 433.79 g, respectively) and mortality rates (C3 = 20.58%, C4 = 24.58%). Results suggest that if the weight of the bitch is >16.1 kg in eutocic births, there is a higher risk of intrapartum physiological alterations and death. The results of this study allowed us to identify that the weight of dams before birth determines the weight of the puppies at birth.

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Adaptation to extrauterine life brings about various changes, which initially are reflected in physiological alterations in the newborn puppy. Also, the newborn puppy's thermoregulating capacity is deficient, and many of the physiological processes for survival depend on this capacity. Severe modifications in body temperature can lead to hypothermia in a few hours. Hence, the first 24 to 72 h of life correspond to the highest risk time, in which the newborn can course with moderate to severe hypothermia because the shivering reflexes and vasoconstriction mechanisms are not yet developed in the newborn of this species. Temperature stabilization is reached up to the 18th day of age. However, the colostrum's adequate consumption could provide a high energy supply, contributing to a fast recovery of temperature and, consequently, to a high survival rate. This review aims to analyze the factors that affect thermoregulation of the newborn puppy, the physiological and behavioral responses, as well as to discuss the influence of the colostrum as an energy source and production of heat to face hypothermia, aside from discussing recent scientific findings of infrared thermography (IRT) used to assess the thermal response of the newborn puppy to cope with hypothermia.

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RESUMO

Adaptation to extrauterine life brings about various changes, which initially are reflected in physiological alterations in the newborn puppy. Also, the newborn puppy's thermoregulating capacity is deficient, and many of the physiological processes for survival depend on this capacity. Severe modifications in body temperature can lead to hypothermia in a few hours. Hence, the first 24 to 72 h of life correspond to the highest risk time, in which the newborn can course with moderate to severe hypothermia because the shivering reflexes and vasoconstriction mechanisms are not yet developed in the newborn of this species. Temperature stabilization is reached up to the 18th day of age. However, the colostrum's adequate consumption could provide a high energy supply, contributing to a fast recovery of temperature and, consequently, to a high survival rate. This review aims to analyze the factors that affect thermoregulation of the newborn puppy, the physiological and behavioral responses, as well as to discuss the influence of the colostrum as an energy source and production of heat to face hypothermia, aside from discussing recent scientific findings of infrared thermography (IRT) used to assess the thermal response of the newborn puppy to cope with hypothermia.(AU)

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For the past years, there is an increased interest for maternal behavior in human’s best friend – the dog. Indeed, studies show that the quality of mothering is not only important for the survival of the puppies during the first weeks of life, for the bonding process but recently it shows that it might have a long-lasting impact on the puppies’ future performance. However, how to define and measure maternal behavior? From the early studies to nowadays, the display of acts from the bitch right prior to parturition (preparation phase), and then continuously toward the puppies until weaning are the repertoire of actions that define maternal behavior. For the scientific community, maternal care is quantified as a principal component assessing attitudes that are easy to measure from the dam to the puppies such as: the time spent in contact, time and/or frequency of licking/grooming and time and position of nursing. Though, there is still a need to elucidate different aspects of maternal behavior in the dog, for example the effect of genetics, the impact of the emotional state of the bitch and the quality of maternal behavior, the role of hormones, the possibility to improve maternal behavior, there is some information to share. The idea is to give an overview of maternal behavior that permits veterinarians, breeders to identify and prevent problems to optimize the dog welfare.

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Pentatrichomonas hominis and Tritrichomonas foetus (cat genotype) have been commonly identified as intestinal trichomonads in both dogs and cats. Although P. hominis is considered as non-pathogenic protozoa in many kinds of mammals, it has the potential for zoonotic transmission. T. foetus has been recognized as the emerging causative agent of diarrhea in cats without the risk of zoonotic transmission. As pet shops are the major source of young companion animals, the present study discusses the molecular prevalence of P. hominis and T. foetus from 544 pet shop puppies and 409 kittens. The results suggest that the prevalence of P. hominis (puppies: 7.0%; kittens: 0.5%) and T. foetus (puppies: 0%; kittens: 2.4%) in pet shop young animals are low. In addition, the infections of P. hominis and T. foetus are not always associated with the clinical signs (soft or diarrhea feces).(AU)

Pentatrichomonas hominis e Tritrichomonas foetus (genótipo de gato) têm sido comumente identificados como trichomonas intestinais em cães e gatos. Apesar de P. hominis ser considerado como protozoário não patogênico em muitos tipos de mamíferos, tem potencial para transmissão zoonótica. Enquanto o T. fetus foi reconhecido como o agente causador emergente de diarreia em gatos sem o risco de transmissão zoonótica. Devido às lojas de animais serem as principais fontes de filhotes de animais domésticos, o presente estudo discute a prevalência molecular e/ou o potencial zoonótico de P. hominis e T. foetus em 544 filhotes de cachorro e 409 gatos de pet shop. Os resultados sugerem que a prevalência de P. hominis (cães: 7,0%; gatos: 0,5%) e T. foetus (cães: 0%; gatos: 2,4%) em animais jovens de pet shop é baixa. Além disso, as infecções de P. hominis e T. foetus nem sempre estão associadas aos sinais clínicos (fezes moles ou diarreia).(AU)

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Abstract Pentatrichomonas hominis and Tritrichomonas foetus (cat genotype) have been commonly identified as intestinal trichomonads in both dogs and cats. Although P. hominis is considered as non-pathogenic protozoa in many kinds of mammals, it has the potential for zoonotic transmission. T. foetus has been recognized as the emerging causative agent of diarrhea in cats without the risk of zoonotic transmission. As pet shops are the major source of young companion animals, the present study discusses the molecular prevalence of P. hominis and T. foetus from 544 pet shop puppies and 409 kittens. The results suggest that the prevalence of P. hominis (puppies: 7.0%; kittens: 0.5%) and T. foetus (puppies: 0%; kittens: 2.4%) in pet shop young animals are low. In addition, the infections of P. hominis and T. foetus are not always associated with the clinical signs (soft or diarrhea feces).

Resumo Pentatrichomonas hominis e Tritrichomonas foetus (genótipo de gato) têm sido comumente identificados como trichomonas intestinais em cães e gatos. Apesar de P. hominis ser considerado como protozoário não patogênico em muitos tipos de mamíferos, tem potencial para transmissão zoonótica. Enquanto o T. fetus foi reconhecido como o agente causador emergente de diarreia em gatos sem o risco de transmissão zoonótica. Devido às lojas de animais serem as principais fontes de filhotes de animais domésticos, o presente estudo discute a prevalência molecular e/ou o potencial zoonótico de P. hominis e T. foetus em 544 filhotes de cachorro e 409 gatos de "pet shop". Os resultados sugerem que a prevalência de P. hominis (cães: 7,0%; gatos: 0,5%) e T. foetus (cães: 0%; gatos: 2,4%) em animais jovens de "pet shop" é baixa. Além disso, as infecções de P. hominis e T. foetus nem sempre estão associadas aos sinais clínicos (fezes moles ou diarreia).

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Mammalian parental care, in most of the cases, is given by the female, who provides food, warmth, and protection. In domestic dogs, maternal behaviour shown by the dam mainly consists of contact, nursing, grooming/licking, play, punishment, thermoregulation, and motion. Peer-reviewed literature published between 1952 and 2018 was retrieved from CAB Abstracts, PubMed, ISI Web of Knowledge, Scopus and book chapters. Keywords for this search included the following terms: behaviour, bonding, altricial, precocial, offspring, maternal, whelping, nursing, domestic dogs, female dog, aggression, puppies, anogenital licking. In this review, we reported and discussed scientific information about maternal behaviour in domestic bitches, comparing altricial vs precocial species; the importance of the bonding, grooming/licking and nursing, and their impacts on puppies' behaviour; altered maternal behaviours such as aggression, cannibalism, rejection, and also the relation between hormones and maternal care behaviours. We concluded that the level of interactions between the dam and the puppies influences the physiological, cognitive and behavioural development of the litter, and the main hormones in the bitch for inducing maternal care behaviours are estradiol, oxytocin, prolactin and progesterone.

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Canine congenital malformations are structural or functional abnormalities of organs present at birth that possibly interfere with the viability of newborns, thus contributing to neonatal mortality. This study evaluated and described the incidence of congenital malformations in neonatal dogs and determined the mortality rates among those affected. Of the 178 litters and 803 newborns included in the study, 24.7% (44/178) of the litters presented neonates with congenital malformations. The total rate of neonates that presented malformations was 6.7% (64/803). The total mortality rate in newborns with congenital defects was 5.4% (44/803), representing 68.7% (44/64) of the deaths observed among those affected. The early (0-2 days old) and late (3-30 days old) mortality rates among the affected neonates were 61.4% (27/44) and 38.6% (17/44), respectively. In total, 27 malformations were recorded, and the most common congenital defects were cleft palate 2.8% (23/803) and hydrocephaly 1.5% (12/803), either alone or associated with other malformations. The malformations were recorded in 15 breeds: Pug, Miniature Pinscher, Rottweiler, Pitbull, French Bulldog, English Bulldog, Dachshund, Labrador Retriever, Lhasa Apso, Poodle, German Spitz, Yorkshire Terrier, Shih-tzu, Brazilian Terrier and mixed breed. One case of exposure to a teratogenic agent was reported, but no maternal exposure to teratogens during gestation was reported with the other litters. The occurrence of congenital defects may be related to genetic factors since the highest incidence of malformations (84.4%) was observed in purebred dogs.

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BACKGROUND: The dog, Canis familiaris, a domestic animal that maintains close contact with humans and other animals, is considered as a potential source of zoonotic parasites. The current study aimed to determine the frequency of helminth eggs in feces of puppies of dog living in urban or rural environments of Mexico City between spring and summer of 2013. METHODS: Stool samples (n=180) were analyzed by sedimentation with formalin-ether. Samples were collected from puppies living in the urban zone (n=90; stray animals) or in the rural environment (n=90; stray animals, animals with owner and animals confined to a canine control center). RESULTS: Eggs of Toxocara canis (41%), Ancylostoma caninum (8%) and Dipylidium caninum (3%) were found in the rural environment but none in the urban zone. A frequency of 19% of Toxocara eggs was found in the canine control center, while, in stray puppies, the frequency was of 12% and 10% in animals with owner. Eggs of Toxocara were found in 33% samples of puppies with history of antiparasitic treatment. CONCLUSION: This study supports the observation of helminth population reduction in urban environments. Further studies are needed to identify the factors that affect the development and transmission of helminth eggs in urban environments.

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Celulite juvenil ou linfadenite granulomatosa estério é uma dermatose incomum que acomete filhotes principalmente das raças Labrador Retrievier, Golden Retrievier, Teckel, Beagle e Pointer. A fisiopatologia ainda é desconhecida, porém sugere-se participação de estímulo antigênico vacinal. Os sinais clínicos incluem edema, pápulas, pústulas, alopecia e crostas principalmente em região facial. O diagnóstico é fundamentado na resenha, sinais clínicos, citologia e/ou histopatologia cutânea. O tratamento baseia-se na utilização de medicações imunossupressoras por um longo período. O prognóstico é bom se o diagnóstico e tratamento forem precoces. O objetivo deste trabalho é relatar um caso atendido no Hospital Veterinário da Faculdade de Medicina Veterinária de Araçatuba - UNESP, em um canino, filhote, sem raça definida apresentando sinais clínicos compatíveis com celulite juvenil.(AU)

Juvenile cellulitis or granulomatous sterile lymphadenitis is a rare skin disease that occurs mainly puppies of breeds Labrador Retrievier, Golden Retrievier, Dachshund, Beagle and Pointer. The pathophysiology is unknown but it is suggested participation of vaccine antigen stimulation. Clinical signs include edema, papules, pustules, alopecia and crusts especially in the facial region. Diagnosis is based on the review, clinical, cytology and/or skin histipatologia. Treatment is based on the use of steroids in high doses. The prognosis is good and the diagnosis and treatment is early. The objective of this study is to report a case treated at the veterinary hospital of UNESP - Araçatuba a canine, puppy mongrel showing clinical signs consistent with juvenile cellulitis.(AU)

La celulitis juvenil o granulomatosa estérillinfadenitis es una enfermedad rara de la piel que se produce principalmente cachorros de razas Labrador Retrievier, Golden Retrievier, Dachshund, Beagle y el puntero. La fisiopatología es desconocida, pero se sugiere la participación de la estimulación antígeno de la vacuna. Los signos clínicos incluyen edema, pápulas, pústulas, la alopecia y costras en especial em la región facial. El diagnóstico se basa en la revisión, clínica, citología y/o histipatologia piel. El tratamento se basa en el uso de esteroides en altas dosis. El pronóstico es bueno y el diagnóstico y el tratamiento es precoz. El objetivo de este trabajo es presentar un caso tratado en el Hospital Veterinario de la UNESP - Araçatuba un perro, mestizo perrito manifestado signos clínicos compatibles con celulitis juvenil.(AU)

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Celulite juvenil ou linfadenite granulomatosa estério é uma dermatose incomum que acomete filhotes principalmente das raças Labrador Retrievier, Golden Retrievier, Teckel, Beagle e Pointer. A fisiopatologia ainda é desconhecida, porém sugere-se participação de estímulo antigênico vacinal. Os sinais clínicos incluem edema, pápulas, pústulas, alopecia e crostas principalmente em região facial. O diagnóstico é fundamentado na resenha, sinais clínicos, citologia e/ou histopatologia cutânea. O tratamento baseia-se na utilização de medicações imunossupressoras por um longo período. O prognóstico é bom se o diagnóstico e tratamento forem precoces. O objetivo deste trabalho é relatar um caso atendido no Hospital Veterinário da Faculdade de Medicina Veterinária de Araçatuba - UNESP, em um canino, filhote, sem raça definida apresentando sinais clínicos compatíveis com celulite juvenil.

Juvenile cellulitis or granulomatous sterile lymphadenitis is a rare skin disease that occurs mainly puppies of breeds Labrador Retrievier, Golden Retrievier, Dachshund, Beagle and Pointer. The pathophysiology is unknown but it is suggested participation of vaccine antigen stimulation. Clinical signs include edema, papules, pustules, alopecia and crusts especially in the facial region. Diagnosis is based on the review, clinical, cytology and/or skin histipatologia. Treatment is based on the use of steroids in high doses. The prognosis is good and the diagnosis and treatment is early. The objective of this study is to report a case treated at the veterinary hospital of UNESP - Araçatuba a canine, puppy mongrel showing clinical signs consistent with juvenile cellulitis.

La celulitis juvenil o granulomatosa estérillinfadenitis es una enfermedad rara de la piel que se produce principalmente cachorros de razas Labrador Retrievier, Golden Retrievier, Dachshund, Beagle y el puntero. La fisiopatología es desconocida, pero se sugiere la participación de la estimulación antígeno de la vacuna. Los signos clínicos incluyen edema, pápulas, pústulas, la alopecia y costras en especial em la región facial. El diagnóstico se basa en la revisión, clínica, citología y/o histipatologia piel. El tratamento se basa en el uso de esteroides en altas dosis. El pronóstico es bueno y el diagnóstico y el tratamiento es precoz. El objetivo de este trabajo es presentar un caso tratado en el Hospital Veterinario de la UNESP - Araçatuba un perro, mestizo perrito manifestado signos clínicos compatibles con celulitis juvenil.

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