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1.
Clin Nutr ESPEN ; 63: 676-680, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39089653

RESUMO

BACKGROUND: COVID-19 is a systemic infection with a significant impact on nutrition risk and the hematopoietic system. The neutrophil-lymphocyte ratio (NLR) may have prognostic value in determining severe cases of COVID-19 and the urea-creatinine ratio (UCR) is currently being studied as a potential biomarker of catabolism associated with critical illness. The aim was to assess the association between the NLR, UCR and C-reactive protein (CRP) with nutritional risk in hospitalized patients with COVID-19. METHODS: This is a retrospective cross-sectional study that assessed 589 hospitalized patients with COVID-19, 18 years of age or older, of both sexes. Nutritional risk was assessed by Nutritional Risk Screening (NRS, 2002) and NLR by neutrophils divided by lymphocyte count. The UCR was calculated by the ratio between urea and creatinine and quantified by the calorimetric biochemical method and CRP by the immunoturbidimetric method. Differences between groups were applied by the Mann-Whitney U test and the automated binary regression test. RESULTS: Of the 589 patients, 87.4% were at nutritional risk. When evaluating patients admitted to the ICU, 91.9% were at nutritional risk. Patients with NRS ≥3 are older, with lower body mass and BMI, higher NLR and UCR and lower CRP values. However, 73% of patients admitted to the ward were at nutritional risk, and only age differed between groups, being higher in patients with NRS ≥3. Logistic regression showed a weak association between nutritional risk in NRS and UCR (Model 1) (OR = 0.96, 95%CI: 0.94-0.99, p = 0.003) and NRS with CRP (Model 1) (OR = 1.01, 95%CI: 1.00-1.02, p < 0.001) in patients in the ICU. On the other hand, the logistic regression in ward patients found association only for CRP in both models (Model 1, OR = 1.01, 95%CI: 1.00-1.01, p = 0.041) and (Model 2, OR = 1.01, 95%CI: 1.00-1.01, p = 0.031). CONCLUSION: We found a weak association between nutritional risk and UCR and CRP levels in patients admitted to the ICU, while in the ward patients the nutritional risk also had weak association with CRP.


Assuntos
Biomarcadores , Proteína C-Reativa , COVID-19 , Creatinina , Hospitalização , Estado Nutricional , SARS-CoV-2 , Ureia , Humanos , COVID-19/sangue , Masculino , Feminino , Estudos Transversais , Proteína C-Reativa/metabolismo , Proteína C-Reativa/análise , Pessoa de Meia-Idade , Idoso , Estudos Retrospectivos , Creatinina/sangue , Ureia/sangue , Biomarcadores/sangue , Avaliação Nutricional , Neutrófilos , Idoso de 80 Anos ou mais , Fatores de Risco , Adulto , Desnutrição/sangue
2.
Nutr Neurosci ; : 1-10, 2024 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-38848348

RESUMO

INTRODUCTION: Malnutrition risk (MR) in older adults with neurological disorders is high, but there is little evidence for validated screening tools in this group, as well as for the clinical and socioeconomic factors associated with a high MR. OBJECTIVES: To determine the association of MR using the Malnutrition Universal Screening Tool (MUST) with mortality and length of stay (LOS) in older adults with neurological diseases. Secondarily, the association of clinical, and socioeconomic factors with MR and clinical outcomes was sought. METHODS: A retrospective cohort study was carried out at a third-level neurological disease referral center in Mexico. All patients older than 60 years admitted from January 2017 to December 2018 were considered. MUST, clinical and socioeconomic factors were assessed at hospital admission. Outcomes were followed up to hospital discharge or a maximum of 6 months. RESULTS: A total of 765 patients were included, of whom 24.7% (n = 189) were at high risk. A high MR was independently associated with mortality (OR 3.09; 95% CI 1.60-5.98, p = .001) and LOS >14 days (OR 4.38; 95% CI 2.79-6.89, p = <.001). The only factors independently associated with high MR was economic dependence and unemployment. Patients with high MR and economic dependence (OR 4.0; 95% CI 1.34-11.99, p = .013) or unemployment (OR 3.43; 95% CI 1.17-10.06, p = .025) had the highest mortality. CONCLUSIONS: In hospitalized older adults with neurological diseases, high MR is independently associated with increased mortality and LOS. Economic dependence or unemployment are associated with worse clinical outcomes in patients with high MR.

3.
Int J Hematol Oncol Stem Cell Res ; 18(2): 147-155, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38868803

RESUMO

Background: Hematological cancer patients are prone to the development of sarcopenia and impaired nutritional and functional status. SARC-CalF is a screening tool for the risk of sarcopenia that has shown good results in this population. This study aimed to identify the risk of sarcopenia by SARC-CalF and to verify its association with nutritional status and Hand Grip Strength (HGS) in patients with hematological cancer. Materials and Methods: Adult patients, of both sexes, with hematological cancer, and in outpatient care participated in the study. We measured the Hand Grip Strength of the Dominant Hand (HGSD) and the Adductor Pollicis Muscle Thickness of the Dominant Hand (APMTD). Moreover, we applied the Patient-Generated Subjective Global Assessment (PG-SGA) and SARC-CalF. Data were analyzed with SPSS® software, 22.0, with a significance level of 5.0%. Results: Fifty-one patients aged an average of 60.4 ± 15.1 years were evaluated. Of those, 58.8% were elderly, 51% female, and 80.4% declared themselves non-white. The predominant diagnosis was Mature B Lymphoid Cell Neoplasia (37.7%), and 60.8% of the patients had a diagnosis time of ≤ 3 years. PG-SGA revealed that 35.3% of the patients were malnourished; APMTD and HGSD revealed that 60.8% and 25.5% had reduced muscle strength, respectively. SARC-CalF exposed that 39.2% of the patients were at risk for sarcopenia. Significant associations were found between SARC-CalF and diagnosis time ≤ 3 years (p = 0.039), PG-SGA (p = 0.020), APMTD (p = 0.039) and HGSD (p = 0.002). After binary logistic regression adjusted for age and sex, the reduced HGSD remained associated with the risk of sarcopenia. Conclusion: SARC-CalF identified a risk of sarcopenia in 39.2% of patients. The reduced HGSD was associated with the risk of sarcopenia.

4.
J Clin Med ; 13(5)2024 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-38592073

RESUMO

Background: Malnutrition is an underdiagnosed condition that negatively affects the clinical outcomes of patients, being associated with an increased risk of adverse events, increased hospital stay, and higher mortality. Therefore, nutritional assessment is a required and necessary process in patient care. The objective of this study was to identify the factors associated with nutritional risk by applying the Malnutrition Universal Screening Tool (MUST) scale in a population of critically ill patients. Methods: This was an observational, analytical, and retrospective study. Sociodemographic, clinical, hematological, and biochemical variables and their relationship with nutritional risk and mortality were analyzed. Results: Of 630 patients, the leading cause of admission was pathologies of the circulatory and respiratory system (50%); 28.4% were at high nutritional risk; and mortality was 11.6% and associated with nutritional risk, hemoglobin, and plasma urea nitrogen. Conclusions: The presence of gastrointestinal symptoms and the type of nutritional support received during hospitalization could increase the likelihood of presenting a medium/high nutritional risk, while polycythemia reduced this probability. An associative model was found to determine nutritional risk with an adequate specificity and diagnostic validity index.

5.
Geriatr Gerontol Int ; 24(3): 312-318, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38323744

RESUMO

OBJECTIVES: The prognostic value of hematological markers has not been extensively explored in the geriatric population, particularly in the presence of the frailty phenotype among hospitalized individuals. Therefore, our study aimed to assess the influence of the frailty phenotype in hospitalized geriatric individuals on hematological markers and their impact on short- and long-term outcomes. METHODS: This is a secondary analysis of a prospective cohort study. This study involved hospitalized individuals who were followed during their hospitalization and for nearly 2 years after discharge. At baseline, Fried's frailty phenotype was assessed, as well as hematological markers, including neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, neutrophil-monocyte ratio, platelet-lymphocyte ratio, systemic inflammation index, prognostic nutritional index, geriatric nutritional risk index (GNRI), and C-reactive protein-albumin ratio. The phase angle derived from bioelectrical impedance analysis was likewise considered a prognostic biomarker. Our main outcomes were hospital length of stay and mortality during follow-up. RESULTS: Frailty occurred in 43.2% of the population. Individuals with the frailty phenotype exhibited worse hematological markers and lower phase angle values. Low GNRI and elevated C-reactive protein-albumin ratio values were independently associated with mortality (hazard ratio = 6.88, 95% confidence interval 2.0-23.6; hazard ratio = 2.2, 95% confidence interval 1.1-4.4). Only higher values of the systemic inflammation index were independently associated with prolonged hospital stays. CONCLUSION: Hematological markers may serve as a feasible tool for prognostic assessment. Individuals with the frailty phenotype and low GNRI represented a worst-case scenario. Geriatr Gerontol Int 2024; 24: 312-318.


Assuntos
Fragilidade , Desnutrição , Humanos , Idoso , Prognóstico , Estado Nutricional , Estudos Prospectivos , Proteína C-Reativa , Avaliação Nutricional , Inflamação/diagnóstico , Avaliação Geriátrica , Fatores de Risco , Desnutrição/epidemiologia
6.
An. Fac. Cienc. Méd. (Asunción) ; 56(3): 40-50, 20231201.
Artigo em Espanhol | LILACS | ID: biblio-1519368

RESUMO

El perfil nutricional de los pacientes ostomizados adquiere especial atención debido a las condiciones que podrían predisponer a una malnutrición. El objetivo del estudio fue determinar el perfil nutricional de pacientes ostomizados que reciben atención ambulatoria en el Hospital General del Segundo Departamento de San Pedro-Paraguay - Corea, en el año 2022, se realizó un estudio observacional de corte transversal. Los datos obtenidos fueron cargados en una planilla electrónica Microsoft-Excel, para el análisis se utilizó estadística descriptiva. Para describir el estado nutricional de los pacientes se emplearon indicadores antropométricos y el Screening de Riesgo Nutricional (NRS-2002), aplicados mediante entrevista y evaluación clínica nutricional. El estudio tuvo una duración global de 9 meses, fueron incluidos 20 pacientes ostomizados atendidos en el Programa Nacional de Atención Integral al Paciente Ostomizado provisto por el Hospital General Paraguay-Corea que cumplieron con los criterios de inclusión. Se respetaron los principios éticos de investigación. El grupo etario más representativo fue el de 41 a 64 años o más, seguido del grupo etario de 20 a 40 años; mayor proporción de sexo masculino, procedencia rural. El tipo de ostomía más frecuente fue colostomía terminal seguido de colostomía laterales; enfermedad de base más frecuente fue el de tipo oncológico, seguida de obstrucción intestinal, trauma y por último fistulas y enfermedad diverticular. En conclusión, la apreciación global del estado nutricional evaluada mediante la herramienta NRS-2002 indicó que el perfil nutricional de los pacientes ostomizados presenta riesgo de malnutrición en todos los casos evaluados.


The nutritional profile of ostomized patients acquires special attention due to the conditions that could predispose to malnutrition. The objective of the study was to determine the nutritional profile of ostomized patients who receive outpatient care at the General Hospital of the Second Department of San Pedro-Paraguay Korea, in the year 2022, an observational study of a cross-section was conducted. The data obtained were loaded in an electronic form Microsoft-Excel, for the analysis was used descriptive statistics. To describe the nutritional status of patients, anthropometric indicators and nutritional risk screening (NRS-2002) were used, applied through nutritional clinical interview and evaluation. The study had a global duration of 9 months, 20 ostomized patients were included in the National Program for Comprehensive Care of the Ostomized Patient provided by the General Paraguay-Corea Hospital that complied with the inclusion criteria. Ethical research principles were respected. The most representative age group was 41 to 64 years or more, followed by the age group from 20 to 40 years; Greater proportion of male sex, rural origin. The most frequent type of ostomy was terminal colostomy followed by lateral colostomy; The most frequent base disease was the oncological type, followed by intestinal obstruction, trauma and finally fistulas and diverticular disease. In conclusion, the global appreciation of the nutritional status evaluated by the NRS-2002 tool indicated that the nutritional profile of ostomized patients has a risk of malnutrition in all cases evaluated.


Assuntos
Ciências da Nutrição/estatística & dados numéricos , Estomia
7.
Nutr Res ; 120: 1-19, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37871448

RESUMO

Nutritional risk screening is fundamental to prevent undesirable outcomes in heart failure (HF). Current reviews of nutritional screening tools encompass both hospitalized and outpatient settings, which may not be suitable because of different clinical manifestations. We hypothesize that multidimensional tools would better identify prognosis of decompensated patients because the tools assess more than isolated aspects. This systematic review aims to explore the association of multidimensional nutritional risk screening tools and prognosis in patients hospitalized with decompensated HF. Five databases were searched for studies that assessed nutritional risk through multidimensional screening tools and its association with prognosis in adults hospitalized with decompensated HF. The 95% confidence interval and relative risk were computed using a random-effects model. Inverse variance method was used. Thirty-eight studies were included. Most studies demonstrated higher nutritional risk was significantly associated with worse prognosis. Quantitative analysis identified higher nutritional risk by using the Mini Nutritional Assessment Short Form (MNA-SF), Controlling Nutritional Status, Geriatric Nutritional Risk Index, and Prognostic Nutritional Index to be associated with all-cause mortality. The MNA-SF demonstrated greater magnitude of association with all-cause mortality in older subjects (relative risk, 4.85; 95% confidence interval, 2.0-11.75). Higher nutritional risk was associated with poor prognosis and higher mortality in patients hospitalized with decompensated HF, especially when screened by MNA-SF. Tools were not directly compared. That might reinforce the importance of evaluating multiple aspects when screening hospitalized HF patients once symptoms associated with decompensation frequently mask the underlying nutritional status and risk. PROSPERO registration number (CRD42021256271).


Assuntos
Insuficiência Cardíaca , Desnutrição , Humanos , Idoso , Estado Nutricional , Avaliação Nutricional , Desnutrição/diagnóstico , Prognóstico
8.
Rev. chil. infectol ; Rev. chil. infectol;40(5): 472-480, oct. 2023. tab
Artigo em Espanhol | LILACS | ID: biblio-1521873

RESUMO

INTRODUCCIÓN: La introducción progresiva de vacunas contra SARS-CoV-2 a partir de 2021, priorizando grupos de mayor edad, podría implicar un cambio en el perfil de pacientes hospitalizados por COVID-19 en el tiempo. OBJETIVO: Comparar las características y evolución de pacientes adultos hospitalizados por COVID-19 en un período anterior en 2020 (PER1) y otro posterior al inicio de la vacunación masiva contra SARS-CoV-2 (PER2). PACIENTES Y MÉTODOS: Se registró edad, género, comorbilidades, complicaciones y evolución de los pacientes hospitalizados por COVID-19 en una clínica privada, en Santiago, Chile. Se calculó el puntaje de gravedad y riesgo nutricional. RESULTADOS: En PER2, los pacientes fueron de menor edad, pero con comorbilidades similares al PER1, excepto por mayor malnutrición por exceso. Los pacientes del PER2 no vacunados requirieron más ventilación mecánica (38,9 vs. 14,3%, p = 0,03) y evolucionaron más gravemente (puntaje 6) que aquellos adecuadamente inmunizados (puntaje 5, p = 0,048). Las variables que más predijeron mortalidad fueron edad > 60 años (OR 28.995) y presencia de riesgo nutricional (OR 5.246). DISCUSIÓN: El cambio en el perfil y evolución de los pacientes hospitalizados con COVID-19 está asociado con la secuencia de priorización de vacunas contra SARS-CoV-2, cuyo efecto redujo las hospitalizaciones y gravedad de COVID-19 en adultos mayores.


BACKGROUND: During the COVID-19 pandemic, the early prioritization of SARS-CoV-2 vaccines for older adults may have affected the characteristics of hospitalized COVID-19 patients over time. AIM: To compare the clinical characteristics and outcomes of adult patients admitted for COVID-19 before (PER1) and after (PER2) the initiation of mass vaccination for SARS-CoV-2. METHODS: Data on age, gender, comorbidities, complications, and outcomes of adult patients hospitalized for COVID-19 in a private clinic of Santiago, Chile, were collected. Scores for COVID-19 severity and nutritional risk were calculated. RESULTS: In PER2, patients were younger but had similar comorbidities, except for a higher prevalence of overweight and obesity compared to PER1. Unvaccinated COVID-19 patients in PER2 required more invasive ventilatory support (38.9% vs. 14.3%, p = 0.03) and had a higher severity score (six) than vaccinated patients (five, p = 0.048). The variables that best predicted mortality were age > 60 years (OR 28,995) and the presence of nutritional risk (OR 5,246). DISCUSSION: Changes in the profile and outcomes of hospitalized patients during the COVID-19 pandemic are associated with the prioritization of SARS-CoV-2 vaccines and their protective effect in reducing hospitalizations and disease severity in older adults.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Vacinas contra COVID-19/administração & dosagem , COVID-19/mortalidade , COVID-19/prevenção & controle , Índice de Gravidade de Doença , Comorbidade , Evolução Clínica , Estado Nutricional , Vacinação/estatística & dados numéricos , Medição de Risco , COVID-19/epidemiologia , Hospitalização/estatística & dados numéricos
9.
Br J Nutr ; 130(8): 1357-1365, 2023 10 28.
Artigo em Inglês | MEDLINE | ID: mdl-36797075

RESUMO

The American Society of Parenteral and Enteral Nutrition recommends nutritional risk (NR) screening in critically ill patients with Nutritional Risk Screening - 2002 (NRS-2002) ≥ 3 as NR and ≥ 5 as high NR. The present study evaluated the predictive validity of different NRS-2002 cut-off points in intensive care unit (ICU). A prospective cohort study was conducted with adult patients who were screened using the NRS-2002. Hospital and ICU length of stay (LOS), hospital and ICU mortality, and ICU readmission were evaluated as outcomes. Logistic and Cox regression analyses were performed to evaluate the prognostic value of NRS-2002, and a receiver operating characteristic curve was constructed to determine the best cut-off point for NRS-2002. 374 patients (61·9 ± 14·3 years, 51·1 % males) were included in the study. Of these, 13·1 % were classified as without NR, 48·9 % and 38·0 % were classified as NR and high NR, respectively. An NRS-2002 score of ≥ 5 was associated with prolonged hospital LOS. The best cut-off point for NRS-2002 was a score ≥ 4, which was associated with prolonged hospital LOS (OR = 2·13; 95 % CI: 1·39, 3·28), ICU readmission (OR = 2·44; 95 % CI: 1·14, 5·22), ICU (HR = 2·91; 95 % CI: 1·47, 5·78) and hospital mortality (HR = 2·01; 95 % CI: 1·24, 3·25), but not with ICU prolonged LOS (P = 0·688). NRS-2002 ≥ 4 presented the most satisfactory predictive validity and should be considered in the ICU setting. Future studies should confirm the cut-off point and its validity in predicting nutrition therapy interaction with outcomes.


Assuntos
Estado Terminal , Nutrição Parenteral , Masculino , Adulto , Humanos , Feminino , Prognóstico , Estudos Longitudinais , Estado Terminal/terapia , Estudos Prospectivos , Estudos Retrospectivos
10.
Cir Cir ; 91(1): 122-130, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36787600

RESUMO

A polytraumatized patient is defined as one who has multiple lesions involving different organs and systems, which are usually serious and lead to life-threatening respiratory or circulatory dysfunction. Traumatic stress in the polytraumatized patient results in many metabolic changes that are evident from the first days, but usually persist for weeks, requiring adequate nutritional support as they influence outcomes. Nutritional treatment should be a priority in the comprehensive treatment of polytraumatized patients since it attenuates the metabolic response to trauma and prevents the deterioration of body reserves. It should be noted that some patients present previous nutritional risk. Nutritional intervention should be considered at the same level as any other therapy that supports organic functions, especially in patients in the intensive care unit. Nutritional intervention in polytraumatized patients is a pillar of treatment that has multiple benefits and can improve prognosis. All efforts must be aimed at the early detection of malnourished patients at nutritional risk and providing timely therapies that improve clinical outcomes.


El paciente politraumatizado se define como aquel que tiene múltiples lesiones que involucran diferentes órganos y sistemas, suelen ser graves y conllevan una disfunción respiratoria o circulatoria que pone en riesgo la vida. El estrés traumático en el paciente politraumatizado da lugar a muchos cambios metabólicos que son evidentes desde los primeros días, pero suelen persistir durante semanas y exigen un adecuado soporte nutricional, ya que influyen en los desenlaces. El tratamiento nutricional debe ser una prioridad en el tratamiento integral de los pacientes politraumatizados, porque atenúa la respuesta metabólica al trauma y evita el deterioro de las reservas corporales (cabe mencionar que algunos pacientes presentan riesgo nutricional previo). La intervención nutricional debe considerarse al mismo nivel que cualquier otra terapia que apoye las funciones orgánicas, sobre todo en pacientes en la unidad de terapia intensiva. La intervención nutricional en pacientes politraumatizados es un pilar en el tratamiento que tiene múltiples beneficios y puede mejorar el pronóstico. Todo esfuerzo debe ir encaminado a la detección temprana de pacientes desnutridos o en riesgo nutricional, y proporcionar de manera oportuna terapias que mejores los desenlaces clínicos.


Assuntos
Unidades de Terapia Intensiva , Humanos , Prognóstico , Estudos Retrospectivos
11.
Front Nutr ; 10: 1183058, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38235441

RESUMO

Introduction: The aim of the present study was to use cluster analysis and ensemble methods to evaluate the association between quality of life, socio-demographic factors to predict nutritional risk in community-dwelling Brazilians aged 80 and over. Methods: This cross-sectional study included 104 individuals, both sexes, from different community locations. Firstly, the participants answered the sociodemographic questionnaire, and were sampled for anthropometric data. Subsequently, the Mini-Mental State Examination (MMSE) was applied, and Mini Nutritional Assessment Questionnaire (MAN) was used to evaluate their nutritional status. Finally, quality of life (QoL) was assessed by a brief version of World Health Organizations' Quality of Life (WHOQOL-BREF) questionnaire and its older adults' version (WHOQOL-OLD). Results: The K-means algorithm was used to identify clusters of individuals regarding quality-of-life characteristics. In addition, Random Forest (RF) and eXtreme Gradient Boosting (XGBoost) algorithms were used to predict nutritional risk. Four major clusters were derived. Although there was a higher proportion of individuals aged 80 and over with nutritional risk in cluster 2 and a lower proportion in cluster 3, there was no statistically significant association. Cluster 1 showed the highest scores for psychological, social, and environmental domains, while cluster 4 exhibited the worst scores for the social and environmental domains of WHOQOL-BREF and for autonomy, past, present, and future activities, and intimacy of WHOQOL-OLD. Conclusion: Handgrip, household income, and MMSE were the most important predictors of nutritional. On the other hand, sex, self-reported health, and number of teeth showed the lowest levels of influence in the construction of models to evaluate nutritional risk. Taken together, there was no association between clusters based on quality-of-life domains and nutritional risk, however, predictive models can be used as a complementary tool to evaluate nutritional risk in individuals aged 80 and over.

12.
Clin Nutr ; 41(10): 2325-2332, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-36099668

RESUMO

BACKGROUND & AIMS: The Global Leadership Initiative on Malnutrition (GLIM) proposed a two-step approach for the malnutrition diagnosis: screening to identify "at risk" patients by any validated nutritional screening tool (NST), followed by a detailed nutritional assessment for diagnosis and grading the severity of malnutrition. Since there are several validated NST, this study aimed to evaluate the complementarity of five NST to GLIM criteria for malnutrition diagnosis in a sample of hospitalized patients. METHODS: A secondary analysis of a longitudinal study. Data collection occurred within 48 h of hospital admission and included clinical, sociodemographic and nutritional data. We applied five tools for nutritional risk (NR) screening: Malnutrition Screening Tool (MST), Malnutrition Universal Screening Tool (MUST), Nutritional Risk in Emergency-2017 (NRE-2017), Nutritional Risk Screening - 2002 (NRS-2002), and Short Nutritional Assessment Questionnaire (SNAQ). GLIM criteria were applied to malnutrition diagnosis considering all five criteria. Patients were followed up until discharge to assess hospital length of stay (LOS) and in-hospital mortality and contacted six months post-discharge to assess hospital readmission and death. We calculated the sensitivity, specificity, predictive positive and negative values (PPV and NPV), and kappa. We grouped patients according to NR and malnutrition status in four categories [i.e. NR(+)/GLIM(+)] and investigated their associations with the clinical outcomes in regression models adjusted to the Charlson Comorbidity Index. RESULTS: Among the 601 patients included (55.8 ± 14.8 years, 51.4% males), 41.6% were malnourished by GLIM criteria. The frequency of NR ranged from 24.0% (NRE-2017) to 35.8% (NRS-2002). MUST had the highest sensitivity (73.6%), NPV (83.6%) and PPV (93.4%). All NST presented specificity higher than 90%, except NRS-2002. The accuracy of NST ranged from 76.3% (SNAQ) to 86.8% (MUST). NR (+)/GLIM (+) by NRE-2017, MST, and MUST increased the risk of in-hospital mortality (HR ranged from 5.34 to 10.10). NR (+)/GLIM (+) increased the odds of LOS ≥10 days (RR between 2.11 and 3.01), readmission (RR between 1.51 and 1.80), and mortality six months after discharge (RR between 3.91 and 5.12), regardless of the NST applied. CONCLUSION: MUST presented the highest metrics of accuracy in comparison to GLIM criteria and was an independent predictor of worse clinical outcomes when nutritional risk was combined to malnutrition diagnosis. So, risk screening by MUST is suggested as the first step of the GLIM approach.


Assuntos
Desnutrição , Avaliação Nutricional , Assistência ao Convalescente , Feminino , Humanos , Liderança , Estudos Longitudinais , Masculino , Desnutrição/diagnóstico , Desnutrição/epidemiologia , Estado Nutricional , Alta do Paciente
13.
J Clin Exp Hepatol ; 12(5): 1333-1348, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36157148

RESUMO

Alcohol-associated liver disease is one of the main causes of chronic liver disease. It comprises a clinical-histologic spectrum of presentations, from steatosis, steatohepatitis, to different degrees of fibrosis, including cirrhosis and severe necroinflammatory disease, called alcohol-associated hepatitis. In this focused update, we aim to present specific therapeutic interventions and strategies for the management of alcohol-associated liver disease. Current evidence for management in all spectra of manifestations is derived from general chronic liver disease recommendations, but with a higher emphasis on abstinence and nutritional support. Abstinence should comprise the treatment of alcohol use disorder as well as withdrawal syndrome. Nutritional assessment should also consider the presence of sarcopenia and its clinical manifestation, frailty. The degree of compensation of the disease should be evaluated, and complications, actively sought. The most severe acute form of this disease is alcohol-associated hepatitis, which has high mortality and morbidity. Current treatment is based on corticosteroids that act by reducing immune activation and blocking cytotoxicity and inflammation pathways. Other aspects of treatment include preventing and treating hepatorenal syndrome as well as preventing infections although there is no clear evidence as to the benefit of probiotics and antibiotics in prophylaxis. Novel therapies for alcohol-associated hepatitis include metadoxine, interleukin-22 analogs, and interleukin-1-beta antagonists. Finally, granulocyte colony-stimulating factor, microbiota transplantation, and gut-liver axis modulation have shown promising results. We also discuss palliative care in advanced alcohol-associated liver disease.

14.
Rev. chil. nutr ; 49(3)jun. 2022.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1388611

RESUMO

RESUMEN Introducción: La desnutrición hospitalaria es un proceso multicausal y de alta prevalencia. La intervención nutricional temprana mejora el pronóstico de los pacientes afectados y reduce los costos sanitarios. Objetivo: Estimar la diferencia de costo efectividad de la atención de rutina comparado con la intervención nutricional temprana, en pacientes en riesgo nutricional, en un Hospital Universitario de alta complejidad entre marzo y octubre de 2012. Materiales y métodos: Estudio de evaluación económica en 165 pacientes adultos hospitalizados de especialidades médicas y quirúrgicas. Se tomó como referencia la información de un estudio de intervención cuasi experimental realizado en el año 2012. Se estratificaran los pacientes de acuerdo a días de estancia hospitalaria, complicaciones y estado nutricional según grupo de intervención y se obtuvieron los costos sanitarios. Resultados: La mediana en el costo por paciente con complicaciones fue de US$ 3.950 en el grupo de intervención nutricional temprana comparado con US$ 5.301 por la atención de rutina; para la estancia hospitalaria fue de US$ 2.462 vs US$ 4.201 y para los recursos derivados de optimización del peso fue de US$ 3.627 vs US$ 5.132 respectivamente. Conclusión: La intervención nutricional temprana en los pacientes en riesgo nutricional, disminuyó los costos derivados de complicaciones, estancia hospitalaria y optimización del estado nutricional.


ABSTRACT Introduction: Hospital malnutrition is a highly prevalent process with multiple causes. Early nutritional intervention improves the prognosis of affected patients and reduces health costs. Objective: To estimate the cost-effectiveness of routine care compared with early nutritional intervention, in patients at nutritional risk, in a high complexity university hospital between March and October 2012. Materials and methods: Economic evaluation study in 165 adult hospitalized medical and surgical specialty patients. The information from a quasi-experimental intervention study conducted in 2012 was taken as a reference. Patients were stratified by intervention group according to days of hospital stay, complications and nutritional status; health costs were also obtained. Results: For the early nutritional intervention group compared to routine care, the median cost per patient with complications was US$ 3,950 vs US$ 5,301; US$ 2,462 vs US$ 4,201 for hospital stay and US$ 3,627 vs US$ 5,132 for resources derived from weight optimization, respectively. Conclusion: The early nutritional intervention in patients at nutritional risk, decreased the costs derived from complications, hospital stay, and optimization of nutritional status.

15.
Med. infant ; 29(1): 30-37, Marzo 2022. Tab, ilus
Artigo em Espanhol | LILACS, UNISALUD, BINACIS | ID: biblio-1367046

RESUMO

Introducción: La malnutrición es un estado de deficiencia o exceso de nutrientes que provoca efectos nocivos y puede alterar el crecimiento aumentando la morbi-mortalidad. Materiales y métodos: estudio retrospectivo, descriptivo. Incluyó niños/as de 1-18 años hospitalizados entre 2016-2018. Se obtuvieron datos de caracterización de la muestra y antropométricos. La herramienta de tamizaje nutricional pediátrico (HTNP) se utilizó para detectar riesgo nutricional y en este subgrupo se analizó: variación de peso, intervención nutricional, complicaciones infecciosas y estadía hospitalaria. El análisis de variables se realizó con SPSS Statistics 20. Resultados: Se evaluaron 745 pacientes, 373 niñas (50,1%). Mediana de edad 7,3 años. Estancia hospitalaria media de 4 días (1-123). Se observó 5,9% emaciados, 56,4% eutróficos, 16,8% sobrepeso y 20,9% obesidad. Con baja talla 13%. Se detectó riesgo nutricional con HTNP en 50,7% de los ingresos. Las patologías de base más frecuentes fueron cardiopatías y neoplasias. En pacientes con riesgo nutricional: estadía hospitalaria media de 5 días, 13,5% cursó con infecciones intrahospitalarias, 68% mantuvo o aumentó de peso durante la internación, 13,5% requirió apoyo nutricional (más utilizado el gavage en 59%). Conclusiones: El niño hospitalizado se encuentra en una situación de vulnerabilidad, por lo que el tamizaje y evaluación nutricional resultan acciones claves para prevenir el deterioro nutricional. En los niños con malnutrición las acciones llevadas a cabo por el Nutricionista Clínico como integrante del equipo de atención, revisten un rol clave para promover y garantizar el derecho de los pacientes a la alimentación adecuada y así mejorar su condición nutricional. (AU)


Introduction: Malnutrition is a state of nutrient deficiency or excess that causes harmful effects and can alter growth increasing morbidity and mortality. Materials and methods: retrospective, descriptive study. Children aged 1-18 years admitted to the hospital between 2016-2018 were included. Sample characterization and anthropometric data were collected. The pediatric nutritional screening tool (PNST) was used to identify nutritional risk and in this subgroup we analyzed: weight variation, nutritional intervention, infectious complications, and length of hospital stay. The analysis of variables was performed with SPSS Statistics 20. Results: 745 patients were evaluated, 373 were girls (50.1%). Median age was 7.3 years. Mean hospital stay was 4 days (1- 123). Among the patients, 5.9% were emaciated, 56.4% eutrophic, 16.8% overweight, and 20.9% obese. Thirteen percent of the patients had short stature. Nutritional risk was detected using HTNP in 50.7% of the admitted patients. The most frequent underlying diseases were heart disease and cancer. In patients at nutritional risk: mean hospital stay was 5 days, 13.5% had hospital-acquired infections, 68% maintained or gained weight during the hospital stay, 13.5% required nutritional support (gavage was the most frequently used in 59%). Conclusions: Hospitalized children are in a vulnerable situation, therefore nutritional screening and evaluation are key actions to prevent nutritional deterioration. In children with malnutrition, the Clinical Nutritionist, as a member of the health care team, plays a key role in promoting and guaranteeing the right of patients to adequate food and thus improve their nutritional condition (AU)


Assuntos
Humanos , Lactente , Pré-Escolar , Criança , Adolescente , Transtornos da Nutrição Infantil/diagnóstico , Transtornos da Nutrição Infantil/dietoterapia , Avaliação Nutricional , Criança Hospitalizada , Programas de Rastreamento/métodos , Estado Nutricional , Hospitais Pediátricos , Estudos Retrospectivos , Fatores de Risco
16.
Aging Clin Exp Res ; 34(5): 1165-1169, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34993907

RESUMO

BACKGROUND: The prevalence of malnutrition in hospitalized elderly patients (HEP) is high. OBJECTIVE: To investigate the behavior of several nutritional indicators and predictors of unfavorable clinical outcome. METHODS: Retrospective study with hospitalized elderly patients (N = 322). Nutritional instruments, indicators and outcome were investigated. Chi-square, Fisher and Mann-Whitney tests and univariate and multiple logistic regression analysis were used. RESULTS: The variables that, jointly, were associated with hospital stay longer than 7 days, include: the presence of complications (p = 0.0328; OR 1.946; IC95% 1.056; 3.585) and nutritional risk according to the NRS-2002 (p = 0.0016; OR 2.080; IC95% 1.322; 3.275). The variable that remained associated with complications in the multiple model was the nutritional risk according to the NRS-2002 (p = 0.0018; OR 2.587; IC95% 1.423; 4.703). CONCLUSION: Nutritional risk using the NRS-2002 is a predictor of clinical outcome in hospitalized elderly patients.


Assuntos
Desnutrição , Avaliação Nutricional , Idoso , Hospitalização , Humanos , Tempo de Internação , Desnutrição/diagnóstico , Desnutrição/epidemiologia , Estado Nutricional , Estudos Retrospectivos , Fatores de Risco
17.
Nutr Rev ; 80(6): 1392-1418, 2022 05 09.
Artigo em Inglês | MEDLINE | ID: mdl-34679168

RESUMO

CONTEXT: Nutritional screening tools (NSTs) are used to identify patients who are at risk of nutritional status (NS) deterioration and associated clinical outcomes. Several NSTs have been developed for hospitalized children; however, none of these were specifically developed for Pediatric Intensive Care Unit (PICU) patients. OBJECTIVE: A systematic review of studies describing the development, application, and validation of NSTs in hospitalized children was conducted to critically appraise their role in PICU patients. DATA SOURCES: PubMed, Embase, Web of Science, Scopus, SciELO, LILACS, and Google Scholar were searched from inception to December 11, 2020. DATA EXTRACTION: The review included 103 studies that applied NSTs at hospital admission. The NST characteristics collected included the aims, clinical setting, variables, and outcomes. The suitability of the NSTs in PICU patients was assessed based on a list of variables deemed relevant for this population. DATA ANALYSIS: From 19 NSTs identified, 13 aimed to predict NS deterioration. Five NSTs were applied in PICU patients, but none was validated for this population. NSTs did not include clinical, NS, laboratory, or dietary variables that were deemed relevant for the PICU population. CONCLUSION: None of the available NSTs were found to be suitable for critically ill children, so a new NST should be developed for this population. AQ6. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration no. CRD42020167898.


Assuntos
Estado Terminal , Estado Nutricional , Criança , Humanos , Unidades de Terapia Intensiva Pediátrica , Programas de Rastreamento , Avaliação Nutricional
18.
Natal; s.n; 20220000. 278 p. tab, graf, ilus.
Tese em Português | LILACS, BBO - Odontologia | ID: biblio-1435099

RESUMO

A doença causada pelo novo coronavírus (COVID-19) é atualmente o mais grave problema de saúde pública no mundo. Considerando a magnitude da doença, bem como os impactos psicossociais e econômicos, avaliar a distribuição temporal e os fatores associados com a mortalidade por COVID-19 em públicos distintos pode fornecer evidências sobre a dinâmica temporal e os grupos com maior risco de óbito. Com as medidas adotadas para o enfrentamento da pandemia, foram verificadas mudanças na prática de profissionais de saúde e professores, sendo importante avaliar o impacto na saúde mental. Nesse contexto, o objetivo deste estudo foi avaliar a morbidade e mortalidade por COVID-19 no Brasil e discutir evidencias sobre impacto da pandemia na saúde mental de profissionais de saúde e professores. Para responder a este objetivo, foram desenvolvidos quatro estudos. No primeiro, de corte transversal, foram incluídos 8.402 crianças e adolescentes de 0 a 19 anos com Síndrome Respiratório Aguda Grave (SRAG) por COVID-19. A taxa de incidência e de mortalidade foi 13,74 e 1,35 por 100.000, respectivamente, com letalidade de 9,81%. Na análise multivariada pela Regressão de Poisson com variância robusta, os fatores associados com maior risco de óbito foram faixa etária < 1 ano, cardiopatia, doenças imunossupressoras, doenças neurológicas e síndrome de Down. No segundo artigo, de revisão sistemática, foi identificado que os instrumentos Mini Nutritional Assessment (MNA), MNA-short form, o Geriatric Nutrition Risk Index, o Nutritional Risk Screening 2002, o Malnutrition Universal Screening Tool, o modified Nutrition Risk in Critically Ill (NUTRIC) score e o Subjective Global Assessmen apresentam elevada sensibilidade para identificação de risco nutricional em idosos com COVID-19. No terceiro artigo, de revisão sistemática sobre a saúde mental de professores em tempos de COVID-19, foi verificado que a prevalência de ansiedade variou de dez a 49,4%, para depressão, de 15,9 a 28,9%, e, para estresse, de 12,6 a 50,6%. Atuar em escolas (em comparação com universidades), ser do sexo feminino e estar vivenciando o retorno às aulas presenciais foram fatores relacionados com maior risco de alterações emocionais. No quarto artigo, uma revisão sistemática com metanálise sobre a ansiedade em profissionais de saúde, foi identificada prevalência de 35% (IC95%: 29-40), sendo maior nas mulheres e nos enfermeiros. Atuar na linha de frente, estar infectado com coronavírus e apresentar doenças crônicas também foram fatores associados com maior risco de ansiedade. Os resultados desta tese evidenciam que apesar de menos prevalente que em idosos, a COVID-19 também acomete considerável quantidade de crianças e adolescentes no Brasil, com maior razão de prevalência para óbito nos que apresentam cardiopatia, doenças imunossupressoras, doenças neurológicas e síndrome de Down. Para os idosos, foi verificado que os instrumentos de triagem nutricional são úteis para a identificação de risco nutricional. Foi registrada elevada prevalência de alterações do estado emocional em profissionais de saúde e professores, havendo a necessidade de medidas em saúde coletiva que visem à prevenção destas alterações nestes profissionais. Há a necessidade de inclusão desta pauta em Vigilância em Saúde, especificamente Saúde do Trabalhador (AU).


The disease caused by the new coronavirus (COVID-19) is currently the most serious public health problem in the world. Considering the magnitude of the disease, as well as the psychosocial and economic impacts, assessing the temporal distribution and factors associated with mortality from COVID-19 in different publics can provide evidence about the temporal dynamics and the groups with the highest risk of death. With the measures adopted to face the pandemic, changes were observed in the professional practice of health professionals and teachers, and it is important to assess the impact on mental health. In this context, the aim of this study was to assess morbidity and mortality from COVID-19 in Brazil and the impact of the pandemic on the mental health of health professionals and teachers. To respond to this objective, four studies were developed. In the first, a cross-sectional study, 8,402 children and adolescents aged 0 to 19 years with Severe Acute Respiratory Syndrome (SARS) due to COVID-19 were included. The incidence and mortality rates were 13.74 and 1.35 per 100,000, respectively, with a mortality rate of 9.81%. In the multivariate analysis using Poisson Regression with robust variance, the factors associated with a higher risk of death were age group < 1 year, heart disease, immunosuppressive diseases, neurological diseases and Down syndrome. In the second article, a systematic review, it was identified that the instruments Mini Nutritional Assessment (MNA), MNA-short form, the Geriatric Nutrition Risk Index, the Nutritional Risk Screening 2002, the Malnutrition Universal Screening Tool, the modified Nutrition Risk in Critically Ill (NUTRIC) score and the Subjective Global Assessmen have high sensitivity for identifying nutritional risk in older adults with COVID19. In the third article, a systematic review on the mental health of teachers in times of COVID-19, it was found that the prevalence of anxiety ranged from ten to 49.4%, for depression, from 15.9 to 28.9%, and, for stress, from 12.6 to 50.6%. Working in schools (compared to universities), being female and experiencing a return to face-to-face classes were factors related to a higher risk of emotional changes. In the fourth article, a systematic review with meta-analysis on anxiety in health professionals, a prevalence of 35% (95%CI: 29-40) was identified, being higher in women and nurses. Working on the front lines, being infected with the coronavirus and having chronic illnesses were also factors associated with a higher risk of anxiety. The results of this thesis show that despite being less prevalent than in the elderly, COVID-19 also affects a considerable number of children and adolescents in Brazil, with a higher prevalence ratio for death in those with heart disease, immunosuppressive diseases, neurological diseases and Down syndrome. A high prevalence of alterations in the emotional state was registered in health professionals and teachers, with the need for collective health measures aimed at preventing these alterations in these professionals. There is a need to include this agenda in Health Surveillance, specifically Occupational Health (AU).


Assuntos
Humanos , Masculino , Feminino , Avaliação Nutricional , Saúde Mental , Morbidade , COVID-19/transmissão , Brasil/epidemiologia , Estudos Transversais/métodos , Análise Multivariada , Mortalidade , Distribuição Temporal
19.
Natal; s.n; 20220000. 278 p. tab, graf, ilus, maps.
Tese em Português | LILACS, BBO - Odontologia | ID: biblio-1442978

RESUMO

A doença causada pelo novo coronavírus (COVID-19) é atualmente o mais grave problema de saúde pública no mundo. Avaliar a distribuição temporal e os fatores associados com a mortalidade por COVID-19 em públicos distintos pode fornecer evidências sobre a dinâmica temporal e os grupos com maior risco de óbito. Ademais, com as medidas adotadas para o enfrentamento da pandemia, foram verificadas mudanças na prática profissional de profissionais de saúde e professores, sendo importante avaliar o impacto na saúde mental. Nesse contexto, o objetivo deste estudo foi avaliar a morbidade e mortalidade por COVID-19 no Brasil e o impacto da pandemia na saúde mental de profissionais de saúde e professores. Para responder a este objetivo, foram desenvolvidos quatro estudos. No primeiro, de corte transversal, foram incluídos 8.402 crianças e adolescentes de 0 a 19 anos com SRAG por COVID-19. A taxa de incidência e de mortalidade foi 13,74 e 1,35 por 100.000, respectivamente, com letalidade de 9,81%. Na análise multivariada pela Regressão de Poisson com variância robusta, os fatores associados com maior risco de óbito foram faixa etária < 1 ano, cardiopatia, doenças imunossupressoras, doenças neurológicas e síndrome de Down. No segundo artigo, de revisão sistemática, foi identificado que os instrumentos Mini Nutritional Assessment (MNA), MNA-short form, o Geriatric Nutrition Risk Index, o Nutritional Risk Screening 2002, o Malnutrition Universal Screening Tool, o modified Nutrition Risk in Critically Ill (NUTRIC) score e o Subjective Global Assessmen apresentam elevada sensibilidade para identificação de risco nutricional em idosos com COVID-19. No terceiro artigo, de revisão sistemática sobre a saúde mental de professores em tempos de COVID-19, foi verificado que a prevalência de ansiedade variou de dez a 49,4%, para depressão, de 15,9 a 28,9%, e, para estresse, de 12,6 a 50,6%. Atuar em escolas (em comparação com universidades), ser do sexo feminino e estar vivenciando retorno às aulas presenciais foram fatores relacionados com maior risco de alterações emocionais. No quarto artigo, uma revisão sistemática com metanálise sobre a ansiedade em profissionais de saúde, foi identificada prevalência de 35% (IC95%: 29-40), sendo maior nas mulheres e nos enfermeiros. Atuar na linha de frente, estar infectado com coronavírus e apresentar doenças crônicas também foram fatores associados com maior risco de ansiedade. Os resultados desta tese evidenciam que apesar de menos prevalência que em idosos, a COVID-19 também acomete considerável quantidade de crianças e adolescentes no Brasil. Para os idosos, foi verificado que os instrumentos de triagem nutricional são úteis para a identificação de risco nutricional. Foi registrada elevada prevalência de alterações do estado emocional em profissionais de saúde e professores, havendo a necessidade de medidas em saúde coletiva que visem à prevenção destas alterações nestes profissionais. Há a necessidade de inclusão desta pauta em Vigilância em Saúde, especificamente Saúde do Trabalhador (AU).


The disease caused by the new coronavirus (COVID-19) is currently the most serious public health problem in the world. Considering the magnitude of the disease, as well as the psychosocial and economic impacts, assessing the temporal distribution and factors associated with mortality from COVID-19 in different publics can provide evidence about the temporal dynamics and the groups with the highest risk of death. With the measures adopted to face the pandemic, changes were observed in the professional practice of health professionals and teachers, and it is important to assess the impact on mental health. In this context, the aim of this study was to assess morbidity and mortality from COVID-19 in Brazil and the impact of the pandemic on the mental health of health professionals and teachers. To respond to this objective, four studies were developed. In the first, a cross-sectional study, 8,402 children and adolescents aged 0 to 19 years with Severe Acute Respiratory Syndrome (SARS) due to COVID-19 were included. The incidence and mortality rates were 13.74 and 1.35 per 100,000, respectively, with a mortality rate of 9.81%. In the multivariate analysis using Poisson Regression with robust variance, the factors associated with a higher risk of death were age group < 1 year, heart disease, immunosuppressive diseases, neurological diseases and Down syndrome. In the second article, a systematic review, it was identified that the instruments Mini Nutritional Assessment (MNA), MNA-short form, the Geriatric Nutrition Risk Index, the Nutritional Risk Screening 2002, the Malnutrition Universal Screening Tool, the modified Nutrition Risk in Critically Ill (NUTRIC) score and the Subjective Global Assessmen have high sensitivity for identifying nutritional risk in older adults with COVID19. In the third article, a systematic review on the mental health of teachers in times of COVID-19, it was found that the prevalence of anxiety ranged from ten to 49.4%, for depression, from 15.9 to 28.9%, and, for stress, from 12.6 to 50.6%. Working in schools (compared to universities), being female and experiencing a return to face-to-face classes were factors related to a higher risk of emotional changes. In the fourth article, a systematic review with meta-analysis on anxiety in health professionals, a prevalence of 35% (95%CI: 29-40) was identified, being higher in women and nurses. Working on the front lines, being infected with the coronavirus and having chronic illnesses were also factors associated with a higher risk of anxiety. The results of this thesis show that despite being less prevalent than in the elderly, COVID-19 also affects a considerable number of children and adolescents in Brazil, with a higher prevalence ratio for death in those with heart disease, immunosuppressive diseases, neurological diseases and Down syndrome. A high prevalence of alterations in the emotional state was registered in health professionals and teachers, with the need for collective health measures aimed at preventing these alterations in these professionals. There is a need to include this agenda in Health Surveillance, specifically Occupational Health (AU).


Assuntos
Humanos , Saúde Mental , Morbidade , Pessoal de Saúde/psicologia , COVID-19/epidemiologia , Brasil/epidemiologia , Estudos Transversais/métodos , Análise Multivariada , Distribuição Temporal
20.
Pediátr Panamá ; 50(2): 5-10, 1 October 2021.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1343236

RESUMO

Introducción: La desnutrición intrahospitalaria tiene grandes implicaciones socio-económicas para los países. Sus manifestaciones dependen del grado, tiempo de evolución, déficit ponderal y edad del niño. El objetivo de este estudio es conocer el riesgo nutricional de los pacientes hospitalizados en la Sala de Medicina del Hospital de Especialidades Pediátricas. Métodos: Estudio descriptivo, transversal, pacientes de ambos sexos de 1 mes a 15 años de edad, ingresados a la sala de medicina del Hospital de Especialidades Pediátricas en noviembre de 2014. Se aplicaron dos métodos de tamizaje nutricional, Screening Tool for Assessment of Malnutrition in Paediatrics (STAMP) y Screening Tool for Risk On Nutritionational status and Growth (STRONGKIDS) y se estableció el riesgo nutricional de cada sujeto en estudio. Resultados: 147 pacientes participaron en el estudio. La edad promedio fue de 4,5 años (DE: 4,8), la mayoría eran lactantes (50,3%), con predominio del sexo masculino (56%). Se encontró desnutrición al momento del ingreso en el 12,8% y sobrepeso-obesidad en el 26,6%. STAMP clasificó al 18,3% de la muestra con riesgo nutricional elevado. Dicho método mostró una sensibilidad 57,8% y una especificidad del 87,5%. En cuanto a la prueba de tamizaje STRONGKIDS identificó a un 12,2% con riesgo elevado, con una sensibilidad de 47,3% y especificidad del 92,3%. La concordancia (k) entre STAMP y la evaluación nutricional fue de 0,38 y en el caso de STRONGKIDS fue de 0,41. Conclusiones: Podemos concluir que la prevalencia de desnutrición al momento del ingreso fue del 12,8%. Ambas pruebas de tamizaje nutricional mostraron una buena especificidad (>80%). El riesgo nutricional se correlaciona con las medidas antropométricas principalmente en STRONGKIDS.


Introduction: Malnutrition in hospitalized patients is a prevalent condition and is associated with many adverse outcomes. It depends on the degree, time of evolution, weight deficit and age of the child. There is a direct relationship between nutritional deterioration and longer hospitalization time, causing an increase in the frequency of complications and increased mortality. The objective of this study is to know the nutritional risk of hospitalized patients at Hospital de Especialidades Pediátricas Omar Torrijos Herrera. Methods and materials: Cross-sectional descriptive study with patients evaluated within 48 hours of admission. Patients were aged 1 month or older, both sexes, admitted to the medicine room at Hospital de Especialidades Pediátricas in November 2014. Nutritional risk was assessed by two nutritional screening methods: STAMP and STRONGKIDS. Nutritional status was classified through anthropometrics measurements. The study was approved by the Research Ethics Committee and the signing of the informed consent was required before its inclusion in the study. Results: We evaluated 147 patients aged 4.5 ± 4.8 years, 50.3% were infants and with a predominance of males (56%). The prevalence of malnutrition was 12.8% and for overweight-obesity was 26.6%. STAMP classified 18.3% of patients as high nutritional risk. This method showed a sensitivity of 57.8% and a specificity of 87.5%. Regarding, STRONGKIDS identified 12.2% of patients at high risk, with a sensitivity of 47.3% and specificity of 92.3%. The concordance (k) between STAMP and nutritional evaluation was 0.38 and in the case of STRONGKIDS it was 0.41. Conclusion: The prevalence of malnutrition at the time of admission was 12.8%. STAMP and STRONG KIDS demonstrated high specificity. Nutritional risk is correlated with anthropometric measures mainly in STRONGKIDS. Further studies are required to analyze these tools and nutritional interventions derived from them.

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