RESUMO

Chemical investigation of the aerial parts of Senecio polypodioides lead to the isolation of the new eudesmanoid 1ß-angeloyloxyeudesm-7-ene-4ß,9α-diol (1) and the known dirhamnosyl flavonoid lespidin (3), while from roots, the known 7ß-angeloyloxy-1-methylene-8α-pyrrolizidine (5) and sarracine N-oxide (6), as well as the new neosarracine N-oxide (8), were obtained. The structure of 1 and 8 was elucidated by spectral means. Complete assignments of the (1)H NMR data for 5, 6, sarracine (7), and 8 were made using one-dimensional and two-dimensional NMR experiments and by application of the iterative full spin analysis of the PERCH NMR software.

Assuntos

Raízes de Plantas/química , Alcaloides de Pirrolizidina/isolamento & purificação , Senécio/química , Sesquiterpenos de Eudesmano/isolamento & purificação , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Prótons , Alcaloides de Pirrolizidina/química , Padrões de Referência , Sesquiterpenos de Eudesmano/química , Software