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Anterior cruciate ligament (ACL) instability poses a considerable challenge in traumatology and orthopedic medicine, demanding precise diagnostics for optimal treatment. The pivot-shift test, a pivotal assessment tool, relies on subjective interpretation, emphasizing the need for supplementary imaging. This study addresses this limitation by introducing a machine learning classification algorithm integrated into a mobile application, leveraging smartphones' built-in inertial sensors for dynamic rotational stability assessment during knee examinations. Orthopedic specialists conducted knee evaluations on a cohort of 52 subjects, yielding valuable insights. Quantitative analyses, employing the Intraclass Correlation Coefficient (ICC), demonstrated robust agreement in both intraobserver and interobserver assessments. Specifically, ICC values of 0.94 reflected strong concordance in the timing between maneuvers, while signal amplitude exhibited consistency, with the ICC ranging from 0.71 to 0.66. The introduced machine learning algorithms proved effective, accurately classifying 90% of cases exhibiting joint hypermobility. These quantifiable results underscore the algorithm's reliability in assessing knee stability. This study emphasizes the practicality and effectiveness of implementing machine learning algorithms within a mobile application, showcasing its potential as a valuable tool for categorizing signals captured by smartphone inertial sensors during the pivot-shift test.

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Resumen Antecedentes: Las consultas virtuales aumentaron exponencialmente, pero presentan como limitación la imposibilidad de valorar los signos vitales (SV), siendo especialmente útiles en los pacientes con insuficiencia cardiaca (IC) para titular medicación que modifica pronóstico. Este problema podría potencialmente solucionarse mediante una herramienta que pueda medir la presión arterial (PA) y frecuencia cardiaca (FC) de manera precisa, accesible y remota. Los teléfonos móviles equipados con tecnología de imágenes ópticas transdérmicas podrían cumplir con estos requisitos. Objetivo: Evaluar la precisión de una app basada en imagen óptica transdérmica para estimar SV en relación con la valoración clínica en pacientes con IC. Métodos: Estudio de cohorte prospectivo, se incluyeron pacientes evaluados en una unidad ambulatoria de IC de febrero a abril del 2022. Se valoró simultáneamente la PA y FC mediante la app y el examen clínico (PA con un esfigmomanómetro automatizado y FC por palpación braquial). Se realizaron tres mediciones por app y clínica en cada paciente, por dos médicos independientes, encontrándose ciegos a los resultados. Resultados: Se incluyeron 30 pacientes, con 540 mediciones de TA y de FC. Edad media de 66 (± 13) años, el 53.3% de sexo masculino. La fracción de eyección del ventrículo izquierdo media fue de 37 ± 15, con hospitalizaciones previas por IC el 63.3%, en CF II-III el 63.4%. La diferencia media entre la medición de la app y su medición de referencia clínica fue de 3.6 ± 0.5 mmHg para PA sistólica (PAS), 0.9 ± -0.2 mmHg para PA diastólica (PAD) y 0.2 ± 0.4 lpm para FC. Cuando se promedian las diferencias medias emparejadas para cada paciente, la media entre los 30 pacientes es de 2 ± 6 mmHg para PAS, -0.14 ± 4.6 mmHg para PAD y 0.23 ± 4 lpm para FC. Conclusión: La estimación de PA y FC por una app con tecnología de imagen óptica transdérmica fue comparable a la medición no invasiva en pacientes con IC, y cumple los criterios de precisión de la medición de PA en este estudio preliminar. La utilización de esta nueva tecnología de imagen óptica transdérmica brinda datos prometedores, que deberán ser corroborados en cohortes de mayor tamaño.

Abstract Background: Virtual consultations have increased exponentially, but a limitation is the inability to assess vital signs (VS). This is particularly useful in patients with heart failure (HF) for titrating prognosis-modifying medication. This issue could potentially be addressed by a tool capable of measuring blood pressure (BP) and heart rate (HR) accurately, remotely, and conveniently. Mobile phones equipped with transdermal optical imaging technology could meet these requirements. Objective: To evaluate the accuracy of a transdermal optical imaging-based app for estimating VS compared to clinical assessment in patients with HF. Methods: A prospective cohort study included patients evaluated in an HF outpatient unit between February and April 2022. BP and HR were simultaneously assessed using the app and clinical examination (BP with an automated sphygmomanometer and HR by brachial palpation). Three measurements were taken by both the app and clinic for each patient, by two independent blinded physicians. Results: Thirty patients were included, with 540 measurements of BP and HR. The mean age was 66 (± 13) years, 53.3% were male. The mean left ventricular ejection fraction was 37 ± 15, with 63.3% having previous hospitalizations for HF, and 63.4% in NYHA class II-III. The mean difference between the app measurement and its clinical reference measurement was 3.6 ± 0.5 mmHg for systolic BP (SBP), 0.9 ± -0.2 mmHg for diastolic BP (DBP), and 0.2 ± 0.4 bpm for HR. When averaging the paired mean differences for each patient, the mean across the 30 patients was 2 ± 6 mmHg for SBP, -0.14 ± 4.6 mmHg for DBP, and 0.23 ± 4 bpm for HR. Conclusion: The estimation of BP and HR by an app with transdermal optical imaging technology was comparable to non-invasive measurement in patients with HF and met the precision criteria for BP measurement in this preliminary study. The use of this new transdermal optical imaging technology provides promising data, which should be corroborated in larger cohorts.

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BACKGROUND: Virtual consultations have increased exponentially, but a limitation is the inability to assess vital signs (VS). This is particularly useful in patients with heart failure (HF) for titrating prognosis-modifying medication. This issue could potentially be addressed by a tool capable of measuring blood pressure (BP) and heart rate (HR) accurately, remotely, and conveniently. Mobile phones equipped with transdermal optical imaging technology could meet these requirements. OBJECTIVE: To evaluate the accuracy of a transdermal optical imaging-based app for estimating VS compared to clinical assessment in patients with HF. METHODS: A prospective cohort study included patients evaluated in an HF outpatient unit between February and April 2022. BP and HR were simultaneously assessed using the app and clinical examination (BP with an automated sphygmomanometer and HR by brachial palpation). Three measurements were taken by both the app and clinic for each patient, by two independent blinded physicians. RESULTS: Thirty patients were included, with 540 measurements of BP and HR. The mean age was 66 (± 13) years, 53.3% were male. The mean left ventricular ejection fraction was 37 ± 15, with 63.3% having previous hospitalizations for HF, and 63.4% in NYHA class II-III. The mean difference between the app measurement and its clinical reference measurement was 3.6 ± 0.5 mmHg for systolic BP (SBP), 0.9 ± -0.2 mmHg for diastolic BP (DBP), and 0.2 ± 0.4 bpm for HR. When averaging the paired mean differences for each patient, the mean across the 30 patients was 2 ± 6 mmHg for SBP, -0.14 ± 4.6 mmHg for DBP, and 0.23 ± 4 bpm for HR. CONCLUSION: The estimation of BP and HR by an app with transdermal optical imaging technology was comparable to non-invasive measurement in patients with HF and met the precision criteria for BP measurement in this preliminary study. The use of this new transdermal optical imaging technology provides promising data, which should be corroborated in larger cohorts.

ANTECEDENTES: Las consultas virtuales aumentaron exponencialmente, pero presentan como limitación la imposibilidad de valorar los signos vitales (SV), siendo especialmente útiles en los pacientes con insuficiencia cardiaca (IC) para titular medicación que modifica pronóstico. Este problema podría potencialmente solucionarse mediante una herramienta que pueda medir la presión arterial (PA) y frecuencia cardiaca (FC) de manera precisa, accesible y remota. Los teléfonos móviles equipados con tecnología de imágenes ópticas transdérmicas podrían cumplir con estos requisitos. OBJETIVO: Evaluar la precisión de una app basada en imagen óptica transdérmica para estimar SV en relación con la valoración clínica en pacientes con IC. MÉTODOS: Estudio de cohorte prospectivo, se incluyeron pacientes evaluados en una unidad ambulatoria de IC de febrero a abril del 2022. Se valoró simultáneamente la PA y FC mediante la app y el examen clínico (PA con un esfigmomanómetro automatizado y FC por palpación braquial). Se realizaron tres mediciones por app y clínica en cada paciente, por dos médicos independientes, encontrándose ciegos a los resultados. RESULTADOS: Se incluyeron 30 pacientes, con 540 mediciones de TA y de FC. Edad media de 66 (± 13) años, el 53.3% de sexo masculino. La fracción de eyección del ventrículo izquierdo media fue de 37 ± 15, con hospitalizaciones previas por IC el 63.3%, en CF II-III el 63.4%. La diferencia media entre la medición de la app y su medición de referencia clínica fue de 3.6 ± 0.5 mmHg para PA sistólica (PAS), 0.9 ± ­0.2 mmHg para PA diastólica (PAD) y 0.2 ± 0.4 lpm para FC. Cuando se promedian las diferencias medias emparejadas para cada paciente, la media entre los 30 pacientes es de 2 ± 6 mmHg para PAS, ­0.14 ± 4.6 mmHg para PAD y 0.23 ± 4 lpm para FC. CONCLUSIÓN: La estimación de PA y FC por una app con tecnología de imagen óptica transdérmica fue comparable a la medición no invasiva en pacientes con IC, y cumple los criterios de precisión de la medición de PA en este estudio preliminar. La utilización de esta nueva tecnología de imagen óptica transdérmica brinda datos prometedores, que deberán ser corroborados en cohortes de mayor tamaño.

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OBJECTIVE: To develop a mobile application with a standardized routine, to be used by general otolaryngologists for evaluating patients with chronic rhinosinusitis. METHODS: A systematic review was made to identify outcomes, recommendations and what tests that would be used in the routine evaluation of patients with chronic rhinosinusitis; establish an expert consensus on items to be included in this routine evaluation of patients with chronic rhinosinusitis using the Delphi method; development of an application for use on a mobile device, with the routine evaluation of patients with chronic rhinosinusitis. RESULTS: Based on the systematic review, the outcomes used in studies about chronic rhinosinusitis were identified, as well as guidelines recommendations, which showed discrepancies between them. These recommendations and outcomes were presented to specialists in chronic rhinosinusitis, until a consensus was reached. As a result of the Delphi method, the flowchart of the routine evaluation of patients with chronic rhinosinusitis was defined, and then was used for the development of the mobile application. CONCLUSION: The creation of the mobile application for evaluating patients with chronic rhinosinusitis followed an adequate methodology of elaboration made by specialists in the field of chronic rhinosinusitis, standardizing the investigation of these patients. LEVEL OF EVIDENCE: Level 5.

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Aim: This study aimed to assess the interest of dental students, clinicians and professors in a mobile app for calculating dosages of medicines for use in Pediatric Dentistry. Methods: The cross-sectional survey involved a random sample of undergraduate and postgraduate pediatric dental students, clinical pediatric dentists and professors. Initially, participants watched a video about an early version of the app. They then answered a questionnaire about their clinical experience, calculation routine, and interest in the app. Descriptive analyses were carried out. Results: Of the 41 participants (20 students, 10 clinicians and 11 professors), 87.8% recognized the need to adjust doses of medicines used in pediatric dentistry, but only 56.1% felt confident in doing so. Almost a fifth of participants (19.5%) admitted errors in prescribing medicines for pediatric dental patients. After seeing the app's functionalities, 92.7% considered it relevant, and 87.8% were interested in the full version. Conclusion: The app is deemed relevant, necessary, and of significant interest to the target audience, indicating potential for investment and full development.

Objetivo:Este estudo buscou avaliar o interesse de estudantes de odontologia, clínicos e professores em um aplicativo móvel para calcular dosagens de medicamentos para uso em Odontopediatria. Métodos: A pesquisa transversal envolveu uma amostra aleatória de estudantes de odontologia pediátrica de graduação e pós-graduação, odontopediatras clínicos e professores. Inicialmente, os participantes assistiram a um vídeo sobre uma versão inicial do aplicativo. Em seguida, eles responderam a um questionário sobre sua experiência clínica, rotina de cálculos e interesse no aplicativo. Análises descritivas foram realizadas. Resultados:Dos 41 participantes (20 estudantes, 10 clínicos e 11 professores), 87,8% reconheceram a necessidade de ajustar as doses de medicamentos usados em Odontopediatria, mas apenas 56,1% se sentiam confiantes para fazê-lo. Quase um quinto dos participantes (19,5%) admitiu erros na prescrição de medicamentos para pacientes odontopediátricos. Após verem as funcionalidades do aplicativo, 92,7% o consideraram relevante, e 87,8% demonstraram interesse na versão completa. Conclusão: A conclusão é que o aplicativo é relevante, necessário e de interesse para o público-alvo, indicando potencial para investimento e desenvolvimento completo.

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Abstract Objective To develop a mobile application with a standardized routine, to be used by general otolaryngologists for evaluating patients with chronic rhinosinusitis. Methods A systematic review was made to identify outcomes, recommendations and what tests that would be used in the routine evaluation of patients with chronic rhinosinusitis; establish an expert consensus on items to be included in this routine evaluation of patients with chronic rhinosinusitis using the Delphi method; development of an application for use on a mobile device, with the routine evaluation of patients with chronic rhinosinusitis. Results Based on the systematic review, the outcomes used in studies about chronic rhinosinusitis were identified, as well as guidelines recommendations, which showed discrepancies between them. These recommendations and outcomes were presented to specialists in chronic rhinosinusitis, until a consensus was reached. As a result of the Delphi method, the flowchart of the routine evaluation of patients with chronic rhinosinusitis was defined, and then was used for the development of the mobile application. Conclusion The creation of the mobile application for evaluating patients with chronic rhinosinusitis followed an adequate methodology of elaboration made by specialists in the field of chronic rhinosinusitis, standardizing the investigation of these patients. Level of evidence: Level 5.

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OBJECTIVE: To assess whether using a Dietary Approaches to Stop Hypertension (DASH) diet recommendation application increases primary care physicians' knowledge and dietary counseling skills. DESIGN: A randomized controlled trial. SETTING: Brazilian public primary care service. PARTICIPANTS: Two hundred and twenty-two physicians (intervention group: n = 111; control group: n = 111). INTERVENTION: Thirty days of using the Dieta Dash application. The application provides information about nutritional recommendations for hypertension management. MAIN OUTCOME MEASURES: Nutrition knowledge score. SECONDARY OUTCOMES: self-assessment of knowledge, self-confidence, assessment of eating habits, and barriers to dietary counseling. ANALYSIS: Linear mixed-effects models for repeated measures and generalized estimating equations for comparing changes between groups. RESULTS: A total of 66.2% of participants completed the follow-up. There was no significant difference between the groups regarding the mean knowledge score (P = 0.15). The prevalence of high knowledge increased by 12% (prevalence ratio [PR] = 1.12; 95% confidence interval [CI], 1.00-1.25) in the intervention group and showed an improvement in the self-confidence assessment (PR = 1.21; 95% CI, 1.02-1.44), and increased assessment of eating habits (PR = 1.26; 95% CI, 1.10-1.55). CONCLUSIONS AND IMPLICATIONS: The Dieta Dash application helped address dietary counseling, improving knowledge and self-confidence. However, innovative strategies are needed to minimize the primary care barriers.

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Strategies to stir and mix reagents in microfluid devices have evolved concomitantly with advancements in manufacturing techniques and sensing. While there is a large array of reported designs to combine and homogenize liquids, most of the characterization has been focused on setups with two inlets and one outlet. While this configuration is helpful to directly evaluate the effects of features and parameters on the mixing degree, it does not portray the conditions for experiments that involve more than two substances required to be subsequently combined. In this work, we present a mixing characterization methodology based on particle tracking as an alternative to the most common approach to measure homogeneity using the standard deviation of pixel intensities from a grayscale image. The proposed algorithm is implemented on a free and open-source mobile application (MIQUOD) for Android devices, numerically tested on COMSOL Multiphysics, and experimentally tested on a bidimensional split and recombine micromixer and a three-dimensional micromixer with sinusoidal grooves for different Reynolds numbers and geometrical features for samples with fluids seeded with red, blue, and green microparticles. The application uses concentration field data and particle track data to evaluate up to eleven performance metrics. Furthermore, with the insights from the experimental and numerical data, a mixing index for particles (mp) is proposed to characterize mixing performance for scenarios with multiple input reagents.

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Introducción: El predominio y asequibilidad actual de los teléfonos móviles inteligentes han permitido una amplia difusión de variedad de aplicaciones a nivel mundial para el monitoreo del crecimiento y del estado nutricional de los lactantes. No obstante, la mayoría de estos recursos no son lo suficientemente completos para proveer una interfaz amigable de seguimiento del crecimiento, combinada con una adecuada educación parental en materia de nutrición y alimentación complementaria. Objetivos: Este trabajo pretende presentar el desarrollo y evaluación de la aplicación propuesta "Baby Home", con el fin de estudiar su potencial como herramienta digital de apoyo a padres y cuidadores en el cuidado nutricional de sus niños desde el hogar. Materiales y métodos: Baby Home integra una interfaz de seguimiento interactivo del crecimiento del bebé con una serie de contenidos educativos alimentarios, posibilitando al usuario consultar las prácticas recomendadas según el estado nutricional estimado de su bebé. Un conjunto de 7 jueces expertos fue reunido para evaluar la validez de estos contenidos consignados en la aplicación. Posteriormente, se llevó a cabo un estudio de prueba piloto con 8 madres participantes, las cuales aportaron en las fortalezas y debilidades de las funcionalidades propuestas. Resultados: la aplicación desarrollada muestra una aprobación positiva por los especialistas consultados y una aceptación satisfactoria entre las madres participantes gracias a su diseño amigable y funcionalidades de fácil uso. Los recursos visuales implementados prueban ser adecuados para la apropiación de los contenidos alimentarios y el empoderamiento del usuario en torno a los cuidados nutricionales que requieren sus niños. Conclusiones: Baby Home se ubica como un soporte práctico y accesible para el cuidado nutricional del lactante, otorgando seguridad y confianza al usuario en la alimentación de su niño y disponiendo la posibilidad de detectar oportunamente problemas de crecimiento.

Introduction: The current prevalence and affordability of smartphones have enabled a broad diffusion of a variety of mobile applications worldwide for monitoring infant's growth and nutritional status. However, most of these resources are not comprehensive enough to provide a user-friendly interface for growth tracking combined with proper parental education on nutrition and complementary feeding. Objectives: This work aims to present the development and evaluation of the proposed application "Baby Home", in order to study its potential as a digital tool for supporting parents and caregivers in the nutritional care of their children from home. Materials and methods: Baby Home integrates an interactive baby growth monitoring interface with a collection of educational content on infant feeding, allowing the user to check the recommended practices based on the estimated nutritional status of their baby. A panel of seven expert judges was assembled to evaluate the validity of these contents included in the application. Subsequently, a pilot study was carried out with eight participating mothers who contributed to the strengths and weaknesses of the proposed functionalities. Results: The developed application received positive feedback by the consulted specialists and a satisfactory acceptance within the participating mothers thanks to its friendly design and easy-to-use functionalities. The implemented visual resources proved to be well suited for the user's appropriation of feeding contents and their empowerment regarding the nutritional care required by their children. Conclusions: Baby Home is positioned as a practical and accessible support for the nutritional care of infants, providing safeness and confidence to the user in their child's feeding and the possibility of timely detection of growth problems.

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INTRODUCTION: Medical students are a population at increased risk for anxiety due to their demanding schedule and concerns about potential stigmatization, which often leads to discouragement when seeking help. COVID-19 pandemic has been reported to worsen this issue by restricting social interaction and mobility. To address this problem, an innovative method known as Asynchronous Digital Cognitive Education GAMA-AIMS (DCE GAMA-AIMS) has been introduced. Compared to traditional therapy, this modality can be accessed independently without the guidance of a therapist. OBJECTIVES: To compare the effectiveness of DCE GAMA-AIMS in reducing anxiety scores compared to guided brief Cognitive Behavioral Therapy (guided bCBT). METHODS: A non-blinding RCT was conducted on 66 medical students. The participants were equally divided into two groups, namely intervention and control. The intervention group was given DCE GAMA-AIMS, while the control was administered with guided bCBT. The data obtained were analyzed using independent t-test and ANOVAs. RESULTS: The application had a significant effect on reducing anxiety scores from the 2nd week (M TMAS = 18) to the 8th week (M TMAS = 13). A faster and more significant improvement was observed in the intervention group from the 1st to the 2nd week compared to the control, which began to improve in the 4th week. Furthermore, the intervention group had larger effect sizes (1.32) compared to the control (0.79) from the 1st to 8th week. CONCLUSION: Asynchronous DCE GAMA-AIMS and guided bCBT could reduce TMAS scores in medical students with anxiety, but DCE GAMA-AIMS yielded a greater effect size.

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CONTEXT: Arterial Hypertension (AH) and Diabetes Mellitus (DM) are diseases that are getting worse all over the world. Linked to this advance, is the growing digital health market with numerous mobile health applications, which aim to help patients and professionals in the proper management of chronic diseases. The aim of this study was to analyze, through a systematic review and meta-analysis, the effectiveness of using mobile health applications in monitoring AH and/or DM in the adult and elderly population. METHODS: The systematic review and meta-analysis was carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Metanalyses guidelines and involved searching five databases - Medline/PubMed, Embase, CINAHL, Virtual Library in Health and Cochrane Library. The review included randomized and cohort clinical trials testing the effects of the intervention on changing biochemical parameters and clinical efficacy in people treated for AH and/or DM. The quality of the selected studies was assessed based on the evaluation criteria of the Joanna Briggs Institute tool. The random effects meta-analysis method was used to explain effect distribution between studies, by Stata® software (version 11.0) and publication bias was examined by visual inspection of graphs and Egger test. RESULTS: We included 26 studies in the systematic review and 17 in the meta-analysis. These studies were published between 2014 to 2022 in 14 countries. Were reported improvement in knowledge and self-management of AH and DM, social motivation with treatment and behavioral change, reduction in glycated hemoglobin values, fasting glucose and blood pressure, improvement in adherence to drug treatment, among others. The result of the meta-analysis showed that there is evidence that the use of mobile applications can help reduce glycated hemoglobin by 0.39% compared to the usual care group. CONCLUSIONS: Monitoring and self-monitoring of behaviors and health care related to AH and DM in adults and the elderly through mobile applications, has clinically significant effectiveness in reducing glycated hemoglobin levels. Future studies should provide more evidence and recommendations for best practices and development of digital health interventions. TRIAL REGISTRATION: PROSPERO. International Prospective Registry of Systematic Reviews. CRD42022361928.

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OBJECTIVE: The purpose of this interdisciplinary study was to determine Dominican adolescents' preferences for the content, functionality (i.e. food's glycemic index list, and amount of insulin based on foods' carbohydrate count), and design of a culturally and linguistically relevant mobile application (app) for type 1 diabetes mellitus (T1DM) self-management. The app would facilitate T1DM self-management education and support by addressing providers' challenges in monitoring patients' disease progression and promoting patient adherence to recommended lifestyle changes. Findings inform an app development process that considers the linguistic and cultural values, norms, and structures of people with T1DM and their providers in the Dominican Republic. METHODS: Phone interviews were conducted with 23 adolescents (14 to 18 years of age), using a semistructured questionnaire. The research team conducted the data analysis using NVivo through a deductive and inductive approach. RESULTS: The findings suggest that, regardless of the context, adolescents with T1DM desire similar features and functionalities in a self-management app. Overall, participants preferred an app with a graphic format that has accessible information, a straightforward design, and instructional videos. Participants also desired that an app provide information and reminders about proper eating and insulin administration timing and be a vehicle to access a social network to foster mutual support and encouragement. CONCLUSIONS: Our study highlights adolescents' perspectives on components for inclusion in an app for T1DM self-management. Participants' recommendations for the app's potential usability, contents, and design features will be used to guide the development of a new app to promote engagement and foster better health outcomes.

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Health guidelines inform recommendations for different clinical practices or public health policies. They are a simple way to organize and retrieve relevant information that can impact patient care. Although these documents are easy to use, most are not user-friendly because they are difficult to access. Our work aims to present the developing approach for a decision-making tool based on health guidelines to assist health professionals in caring for patients with tuberculosis. This tool is being developed for use on mobile devices and as a web-based system, which will transform a passive and declarative health guideline document into an interactive tool that will provide data, information, and knowledge. User tests with functional prototypes developed for the Android platform show that this application has the potential to be applied in TB healthcare facilities in the future.

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Traditional learning techniques have evolved slowly and have yet to adapt the course content delivery to today's students' approaches to acquiring new knowledge. However, micro-learning has become popular in e-Learning environments as a course design technique due to short attention spans, demand for small chunks of information, and time constraints. Hence, it has been selected for creating reading mobile applications provided to the nature of its learning approach. In order to describe the multiple iterations of design, development, and evaluation of this general framework, a methodology named Design-Based Research (DBR) is implemented. First, the article presents the abstract framework components and a cloud-based software architecture that allows a modular approach to creating such applications. The pathway developed through adapting the iPAC framework, which involves personalization, authenticity, and collaboration, is part of the methodology used to design the app under pedagogical and technological considerations. The process demanded the following phases: analysis and exploration, design and construction, evaluation and reflection, redesign and reconstruction, and final critical reflections. Four applied instruments also validate the framework implementation: The iPAC Rubric, an aphorisms checklist, a pre and post-test, a focus group, and a usability test taken by 28 students in a private university in Colombia. Findings indicated that Design-Based Research (DBR) methodology emerged as an appropriate tool to encounter the needs behind reading applications design due to its sequence of operations yields results successively closer to adequate usability standards and smooth implementation. They also reveal the positive impact of new types of texts on students' motivation and awareness toward other reading strategies and micro-learning. This impact indeed proved the proposed framework's effectiveness for designing micro-learning applications.

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INTRODUCTION: Stroke is highly prevalent in Latin America and one of the leading causes of morbidity and mortality in the world. Educating children about stroke has been established as an effective method to detect symptoms early, reduce hospital visits, and raise awareness among adults. OBJECTIVE: To analyze the effectiveness of a mobile application to improve knowledge and understanding of stroke among children. METHOD: We conducted a focus group session including 12 children in order to analyze the behavior of 6 questions previously validated by expert neurologists. Subsequently, 105 primary school students between the ages of 7 and 12 completed a questionnaire on stroke symptoms and how to contact the emergency services before and after using an application on stroke symptoms. Qualitative analyses and the Student t test were used to verify the existence of differences between pre- and post-intervention test results. RESULTS: After a single 40-min working session with the application, between 50% and 67% of the children were able to identify the signs of stroke, and 96.2% knew the national emergency services telephone number. Statistical analysis revealed statistically significant differences before and after the intervention with the digital application (t=19.54; p<0.001) and intragroup differences in the post-intervention test results (t=40.71; p<0.001). CONCLUSION: Primary school children who used our digital application increased their knowledge, understanding, and learning of stroke symptoms.

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This article presents original findings from a longitudinal qualitative study on changes in individual and family life associated with safety and health measures implemented during the COVID-19 pandemic in three regions of Chile. We developed a methodological approach based on multimodal diaries in a mobile application, in which participants submitted photographs and texts to express changes in their daily lives under residential confinement. Content and semiotic visual analyses show a significant loss in instances of collective recreation, partially compensated through new personal and productive activities performed at home. Our results suggest that modal diaries serve as potential tools to capture people's perceptions and meanings as their lives go through exceptional and traumatic times. We assert that using digital and mobile technologies in qualitative studies could allow subjects to actively participate in the co-construction of fieldwork and produce quality knowledge from their situated perspectives. Supplementary Information: The online version contains supplementary material available at 10.1007/s11133-023-09531-z.

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A odontologia é uma área de conhecimento fortemente caracterizada por seu aspecto técnico-científico além da forma artesanal com que é desempenhada. Nos últimos anos, alguns fenômenos como a aplicação massiva de tecnologia em seus processos além da ampliação do campo de atuação dos profissionais têm modernizado o setor sem, no entanto, alterar o fato de que a maior parte dos dentistas segue exercendo suas atividades em ambientes clínicos, o que gera demandas por realização de negócios entre pares e profissionais de suporte. Há, contudo, uma significativa barreira à eficácia de transações dessa natureza: a forma descentralizada com que a atuação clínica do dentista se dá, o que mantém esses profissionais recorrendo ao método tradicional da indicação por colegas próximos para comprar, alugar e contratar, reduzindo, dessa forma, as possibilidades de concretização de bons negócios. Em uma sociedade em que "conexão" é uma palavra-chave para o sucesso, torna-se necessária e urgente a modernização da forma como as relações comerciais se dão entre profissionais da odontologia para que esse nicho de oportunidades se torne um relevante mercado nesse setor. Assim, o objetivo desse trabalho foi desenvolver um aplicativo móvel com o propósito de conectar profissionais da odontologia que desejam vender, alugar ou prestar serviços àqueles que desejam comprar, alugar ou contratar de forma ágil, efetiva e confiável em todo o território nacional. Baseada em pesquisas sobre fundamentos, dinâmica e tendências do comércio eletrônico, economia compartilhada, plataformas bilaterais e mercado odontológico, essa ferramenta foi criada por meio da metodologia low-code de desenvolvimento com customização realizada utilizando-se HTML como linguagem de programação, resultando em um aplicativo móvel cujo conteúdo é apresentado sob a forma de anúncios, divididos em 8 categorias e 16 subcategorias. A ferramenta pode ser acessada sem necessidade de download e conta com recursos de busca e ordenação de visualização personalizada, o que confere rapidez à experiência do usuário. Como forma de monetização, será realizada a taxação por anúncio publicado, que poderá receber destaque, sendo exibido em áreas destinadas a esse fim no layout do produto. Tendo recebido o nome de Odontolinks, o aplicativo já está disponível para acesso em sua versão teste e pode ser acessado pelo endereço: https://app.vc/odontolinks. Espera-se que a plataforma Odontolinks se torne a maior referência brasileira em negócios bilaterais no setor odontológico, constituindo-se em uma ferramenta pioneira, efetiva, moderna e segura, promovendo aumento da lucratividade de negócios em odontologia e, consequentemente, de todo o setor além de fomentar a geração de empregos e a consolidação da comunidade odontológica em todo o país(AU)

Dentistry is an area of knowledge strongly characterized by its technical-scientific aspect in addition to the artisanal way in which it is performed. In recent years, some phenomena such as the massive application of technology in its processes in addition to the expansion of the professionals' field of activity have modernized the sector without, however, changing the fact that the majority of dentists continue to carry out their activities in clinical environments. , which generates demands for conducting business between peers and support professionals. There is, however, a significant barrier to the effectiveness of transactions of this nature: the decentralized way in which the dentist's clinical work takes place, which keeps these professionals resorting to the traditional method of being recommended by close colleagues to buy, rent and hire, reducing, thus, the possibilities of achieving good business. In a society where "connection" is a keyword for success, it is necessary and urgent to modernize the way in which commercial relationships occur between dental professionals so that this niche of opportunities becomes a relevant market in this sector. Thus, the objective of this work was to develop a mobile application with the purpose of connecting dental professionals who wish to sell, rent or provide services to those who wish to buy, rent or hire in an agile, effective and reliable way throughout the national territory. Based on research into the fundamentals, dynamics and trends of e-commerce, sharing economy, bilateral platforms and the dental market, this tool was created using a lowcode development methodology with customization carried out using HTML as a programming language, resulting in an application mobile device whose content is presented in the form of advertisements, divided into 8 categories and 16 subcategories. The tool can be accessed without the need for download and has search and sorting features for personalized viewing, which adds speed to the user experience. As a form of monetization, taxation will be carried out per published advertisement, which may be highlighted and displayed in areas designated for this purpose in the product layout. Having received the name Odontolinks, the application is now available for access in its trial version and can be accessed at: https://app.vc/odontolinks. It is expected that the Odontolinks platform will become the biggest Brazilian reference in bilateral business in the dental sector, constituting a pioneering, effective, modern and safe tool, promoting increased profitability of dentistry businesses and, consequently, of the entire sector in addition to promotingjob creation and the consolidation of the dental community across the country (AU)

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O pé diabético é um crescente problema de saúde pública por ser uma complicação incapacitante, mas com caráter prevenível, de 50 a 70% das úlceras de pés são evitáveis, diminuindo o risco de amputações. Para tanto, requer dos profissionais da saúde vigilância constante e ensino das mudanças no comportamento de autocuidado com os pés das pessoas com diabetes mellitus. Nesta direção, há carência de recursos tecnológicos de aplicação móvel para a promoção de hábitos de autoexame e autocuidado com os pés. Desta forma, o objetivo foi o desenvolvimento do protótipo de aplicação móvel "Pés em dia" baseado na metodologia centrada no usuário a fim de apoiar a pessoa com diabetes no autocuidado e autoexame dos pés. Como também, realizar a validação de conteúdo do protótipo por peritos da área de saúde mediado pelo instrumento Suitability Assessment of Materials (SAM) e a validação de usabilidade por peritos da área de tecnologia e informática e as pessoas e familiares com diabetes mellitus mediado pelo Smartphone Usability QuestionnaiRe (SURE). Na elaboração o protótipo teve sua apresentação estrutural e virtual com 21 telas e seu conteúdo organizado em nove telas primárias no menu, doze telas na área dos usuários com os agendamentos, as checagens de autocuidado e autoexame planejados de modo individual. As telas principais oferecem: "Cuide-se" a apresentação, o funcionamento, utilização e créditos, o "Autoexame" e diferenciam as situações dos pés em "pés sem ferida" e "pés com ferida cicatrizadas". E em outra tela "Passos do Autoexame" com textos informativos, multimídias de apoio, achados no autoexame, vídeos do teste do toque para sensibilidade, imagens dos testes de circulação, recursos domésticos, e o reconhecimento das deformidades comuns no contexto da pessoa com DM. O estudo foi realizado na Escola de Enfermagem de Ribeirão Preto, e no desenvolvimento realizou grupos focais com usuários e equipe desenvolvedora para elencar as necessidades do protótipo. Utilizou-se a engenharia de software com compatibilidade para o sistema Android, a linguagem KOTLIN, a estrutura Activity e Fragments e o recurso Navigation Drawer Layout, disponível em Android Studio vídeos e elementos gráficos no Camtasia Studio e Adobe Fireworks, que foram exportados em MP4, JPG e PNG, e armazenados no banco de dados MySQL. Para a validação de conteúdo, os 22 juízes foram selecionados pela expertise e técnica de snowballing, idade média de 37,8 anos (+-7,8), a maioria era do sexo feminino 15 (68,2%), 19 (86,4%) enfermeiros, 9 (40,9%) possuíam mestrado, e 19 (86,3%) participava de grupos de pesquisas nas temáticas de interesse. As respostas dos juízes no instrumento SAM validaram como adequado o protótipo, com o total de 40,3 pontos, (91,7%), a média de 1,85 nas seis categorias, IVCt 0,98 e Alfa de Cronbach 0,936. A maior pontuação nas respostas e IVC foi nas categorias de conteúdo, estimulação/motivação do aprendizado e ilustrações. Quanto a validação de usabilidade, os 22 juízes foram selecionados pela expertise em tecnologia de informática e validação de instrumentos e a técnica de snowballing, a maioria era do sexo masculino 16 (72,7), 6 (27,3%) graduados em Tecnologia da Informática ou Sistema de Informação, 6 (27,3%) Análise de Sistemas ou Programação de Sistemas, 7 (31,8%) com especialização acadêmica, 19 (86,4%) possuíam experiência com a temática. As respostas dos juízes expertise em informática no instrumento SURE consideraram o protótipo pertinente (nível 70 e 80) pois responderam a pontuação 104,8 na média, 22 itens foram avaliados em 100% de concordância, IVCt 0,98, Alfa de Cronbach 0,867, considerado como adequado. A validação de usabilidade pelo público alvo de pessoas com diabetes e seus familiares foi selecionada pela técnica de snowballing, participaram 37 (100%) pessoas, idade média de 48,1 anos (+-13,3), sendo que dessas 21 (56,8%) eram do sexo masculino, 26 (70,3%) com diabetes, tempo médio de 11,5 anos, e 11 (29,7%) eram familiares, 35 (94,6%) não possuía algum tipo de ferida nos pés naquele momento e 24 (64,9%) responderam que não tinham costume de utilizar este tipo de tecnologia. As respostas variaram de 75% a 94,6% de concordância, Alfa de Cronbach 0,989, considerado como adequado. Desta forma, apresenta-se um protótipo móvel "Pés em dia" para promover o autocuidado e autoexame com os pés e validado com o conteúdo e usabilidade adequadas para a literatura e disponíveis gratuitamente para a sociedade.

The diabetic foot is a growing public health problem due to its crippling complication, but with a preventable feature, 50 to 70% of the foot ulcers are preventable, decreasing the risk of amputations. Therefore, it requires constant supervision from health professionals and teaching about changes in self-care behavior with the feet of people with diabetes mellitus (DM). In this sense, there is a lack of technological resources for mobile applications to foment self-examination and self-care habits with the feet. In this way, the objective was the development of the mobile application prototype "Pés em dia" based on the user-focused methodology in order to support, with self-care and self-examination of the feet, the person with diabetes, as well as performing the content validation of the prototype by health-area experts mediated by the Suitability Assessment of Materials (SAM) tool and the usability validation by experts in technology and information technology, as well people and family members with diabetes mellitus mediated by Smartphone Usability QuestionnaiRe (SURE). In the elaboration, the prototype had its structural and virtual presentation with 21 content-organized screens in nine primary screens in the menu and twelve screens in the user's area with the schedules and self-care and self-examination checks individually planned. The mains screens offer: "Take care" as the presentation, operation, using and credits, the "Self-examination" and they differentiate the feet condition in "Feet without wounds" and "Feet with healed wounds" and in another screen "Steps of the self-examination" with informative texts and supporting multimedia and discoveries in the self-examination, touch test videos for sensitivity and images of the circulation testes, the household resources, the recognition of common deformities in the context of the person with DM. The study was conducted at the Ribeirao Preto School of Nursing. For its development, focus groups with users and the development team were carried out to list the requirements of the prototype. Software engineering with Android system compatibility was used, the KOTLIN programming language, the Activity and Fragments structure and the Navigation Drawer Layout resource, available in Android Studio, graphic and video elements in Camtasia Studio and Adobe Fireworks, in which the files were exported in MP4, JPG and PNG, and they were stored in the MySQL database. For the content validation, 22 judges were selected for their expertise and snowballing technique, average age of 37.8 years (+/- 7.8), the most were female (15 women - 68,2%), 19 nurses (86.4%), 9 had a master's degree (40,9%) and 19 (86.3%) participated in research groups on topics of interest. The answers of the judges in the SAM tool validated the prototype as adequate, with a total of 40.3 points (91.7%), an average of 1.85 in the six categories, IVCt 0.98 and Cronbach's alpha 0.936. The highest score in the responses and IVC was in the categories of content, stimulation/motivation of learning and illustrations. Regarding the usability validation, the 22 judges were selected for their expertise in computer technology and tool validation and the snowballing technique, the most of them was male (16 - 72.7%), 6 were graduated in Computer Technology or Information Systems (27,3%), 7 with academic specializations (27.3%), 19 had experience in the subject (86.4%). The answers of the computer-expert judges in the SURE tool considered the prototype relevant levels 70 and 80) as they answered to an average score of 104.8, 22 items were evaluated at 100% agreement, IVCt 0.98, Cronbach's alpha 0.867, which is considered as suitable. The usability validation by the target audience made up of people with diabetes and their families was selected by the snowballing technique, 37 people participated in (100%), average age of 48.1 (+/- 13.3), in which 21 were male (56.8%), 26 had diabetes (70.3%), average time of 11.5 years, 11 were family members (29.7%), 35 did not have any type of feet wound at the moment (94.6%)and 24 answered that they were not acquainted to this technology (64.9%). The answers ranged from 75 to 94.6% agreement, Cronbach's alpha 0.989, which was considered adequate. So, "Pés em dia" mobile prototype is presented to promote self-care and self-examination of the feet and it was validated as adequate content and usability for the literature available at no charge to society.

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Abstract Objective We describe the development and structure of a novel mobile application in a mixed model of prenatal care, in the context of the COVID-19 pandemic. Furthermore, we assess the acceptability of this mobile app in a cohort of patients. Methods First, we introduced a mixed model of prenatal care; second, we developed a comprehensive, computer-based clinical record to support our system. Lastly, we built a novel mobile app as a tool for prenatal care. We used Flutter Software version 2.2 to build the app for Android and iOS smartphones. A cross-sectional study was carried out to assess the acceptability of the app. Results A mobile app was also built with the main attribute of being connected in real-time with the computer-based clinical records. The app screens detail information about activities programmed and developed in the prenatal care according to gestational age. A downloadable maternity book is available and some screens show warning signs and symptoms of pregnancy. The acceptability assessment was mostly rated positively regarding the characteristics of the mobile app, by 50 patients. Conclusion This novel mobile app was developed as a tool among pregnant patients to increase the information available about their pregnancies in the provision of a mixed model of prenatal care in the context of the COVID-19 pandemic. It was fully customized to the needs of our users following the local protocols. The introduction of this novel mobile app was highly accepted by the patients.

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The high prevalence of mental health problems among university students poses a challenge when developing effective interventions, with digital technologies emerging as a potential resource to address this problem. The inclusion of student input in the design and development of such interventions is critical to improving their impact. This study contributed to the initial phase of a research project that aims to adapt and evaluate the feasibility and acceptability of an early intervention for anxiety and depression based on digital technologies for university students. Three participatory workshops were conducted with 13 university students in Chile to inquire about the features and content that a mental health mobile app should include to meet their needs and preferences. The workshop transcripts were analysed using inductive thematic analysis. The results of this study highlight the value of modifications such as the personalisation of some features of the app. The students recommended incorporating topics related to university life and the possibility of contacting a mental health professional, as well as the inclusion of peer interaction or other forms of support.