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State policymakers have long sought to improve access to mental health and substance use disorder (MH/SUD) treatment through insurance market reforms. Examining decisions made by innovative policymakers ("policy entrepreneurs") can inform the potential scope and limits of legislative reform. Beginning in 2022, New Mexico became the first state to eliminate cost-sharing for MH/SUD treatment in private insurance plans subject to state regulation. Based on key informant interviews (n = 30), this study recounts the law's passage and intended impact. Key facilitators to the law's passage included receptive leadership, legislative champions with medical and insurance backgrounds, the use of local research evidence, advocate testimony, support from health industry figures, the severity of MH/SUD, and increased attention to MH/SUD during the COVID-19 pandemic. Findings have important implications for states considering similar laws to improve access to MH/SUD treatment.

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Introduction: The different strategies used worldwide to curb the COVID-19 pandemic between 2020 and 2021 had a negative psychosocial impact, which was disproportionately higher for socially and economically vulnerable groups. This article seeks to identify the psychosocial impact of the confinement period during the COVID-19 pandemic for the Colombian population by identifying profiles that predict the levels of different mental health indicators (feelings of fear, positive emotions or feelings during free time, and work impact) and based on them, characterize the risk factors and protection that allows us to propose guidelines for prevention or recovery from future health emergencies. Methods: This is an observational, cross-sectional, retrospective ex post facto study. Multistage cluster probabilistic sampling and binary logistic regression analysis were used to predict extreme levels of various mental health indicators based on psychosocial indicators of the COVID-19 confinement period and to identify risk and protection factors. Results: A relationship was established between the combination of some of the different psychosocial factors evaluated (this combination being the predictive profile identified) with each of the three main variables: feeling of fear (n = 8,247; R = 0.32; p = 0.00; Poverall = 62.4%; 𝜔overall = 0.25; 1-𝛽overall = 1.00), positive emotions or feelings during free time (n = 6,853; R = 0.25; p = 0.00; Poverall = 59.1%; 𝜔overall = 0.18; 1-𝛽overall = 1.00) and labour impact (n = 4,573; R = 0.47; p = 0.63; Poverall = 70.4%; 𝜔overall = 0.41; 1-𝛽overall = 1.00), with social vulnerability determined by sociodemographic factors that were common in all profiles (sex, age, ethnicity and socioeconomic level) and conditions associated with job insecurity (unemployed, loss of health insurance and significant changes to job's requirements) and place of residence (city). Conclusion: For future health emergencies, it is necessary to (i) mitigate the socio-employment impact from emergency containment measures in a scaled and differentiated manner at the local level, (ii) propose prevention and recovery actions through psychosocial and mental health care accessible to the entire population, especially vulnerable groups, (iii) Design and implement work, educational and recreational adaptation programs that can be integrated into confinement processes.

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SUMMARY: Mast cells (MC) are cells of the immune system that regulate cell and tissue homeostasis, are found in low numbers, have an intact plasma membrane, and a cytoplasm with a wide variety of inflammatory chemical mediators. The activation or degranulation of mast cells implies the release of these chemical mediators (interleukins, cytokines, and more), causing tissue actions ranging from the activation of metalloproteinases to the development of anaphylactic hypersensitivity of different degrees, alterations in vascular permeability, and loss of cell homeostasis. This behavior would allow them to act as sentinels responding to pathophysiological processes. During the COVID-19 pandemic, in positive human patients, the available literature reports the presence and degranulation of mast cells in a generalized manner, especially in the respiratory tract. This study aimed to analyze the emerging role of MCs in the pathogenesis of diseases and their projection as biological markers in the treatment of diseases or pandemics. The analysis of human biopsies showed that MCs are observed as cells with diameters between 8 to 20 µm, and in inflamed tissues, degranulation of MCs is observed. The action of MCs degranulation was related to different inflammatory processes of autoimmune diseases. It is concluded that the potential of MC as therapeutic targets and biomarkers could raise new pharmacological targets, as supportive therapy, and possibly of great help in the treatment of future emerging pandemics such as the current monkeypox.

Los mastocitos (MC) son células del sistema inmune que regulan la homeostasis celular y tisular, se encuentran en escasas cantidades, presentan una membrana plasmática íntegra, y un citoplasma con una amplia variedad de mediadores químicos. La activación o degranulación de los mastocitos implica la liberación de estos mediadores químicos (interleuquinas, citoquina y más), provocando acciones tisulares que van desde la activación de metaloproteinasas hasta el desarrollo de hipersensibilidad anafiláctica de distinto grado, provocando la pérdida de la homeostasis celular. Durante la pandemia de la COVID-19, en pacientes humanos positivos, se informa recurrentemente la presencia y degranulación de mastocitos de manera generalizada sobre todo en las vías respiratorias. El análisis de la degranulación de los MCs podría proporcionar información que podría utilizarse en el desarrollo de tratamientos preventivos contra infecciones virales, bacterianas u otros patógenos. Este comportamiento les permitiría actuar como centinelas en respuesta a procesos fisiopatológicos. El objetivo de este trabajo fue analizar el rol emergente de los MCs en la patogenia de enfermedades y su proyección como marcadores biológicos en el tratamiento de enfermedades o pandemias. En análisis de biopsias humanas se muestran que MCs se observan como células con diámetros de entre 8 a 20 µm, en tejidos inflamados se observa degranulación de MCs. Se relacionó el accionar de degranulación de los MCs en diferentes procesos inflamatorios de enfermedades autoinmunes. Se concluye que el potencial de MC como dianas terapéuticas y biomarcadores podrían plantear nuevos objetivos farmacológicos, como terapia de apoyo, y posiblemente de gran ayuda en el tratamiento de futuras pandemias emergentes como la actual viruela del mono.

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INTRODUCTION: The Indigenous population of the Yanomami ethnic group in Brazil is currently facing a public health emergency due to the high number of deaths, mainly of children. Taking that into consideration, this study aims to analyze this crisis impact on the health of this population in the period between 2018 and 2022. METHODS: The data presented were collected from the report called Yanomami Mission ("Missão Yanomami") published by the Brazilian Ministry of Health and, from it, a descriptive analysis of the Indigenous individuals' health was carried out for (i) the geographical distribution; ii) the number of deaths; (iii) the child death rate; (iv) the deaths of Indigenous individuals from preventable causes; (v) the causes of preventable diseases related to hygiene and basic sanitation, and the distribution of diarrheal diseases according to age groups; (vi) evaluation of the nutritional classification; vii) the percentage (%) of the complete vaccination scheme, and (viii) the coverage of prenatal appointments of Indigenous pregnant women. RESULTS: The report included 31,017 individuals belonging to the Yanomami ethnic group, most of the participants were up to 39 years old (N = 26,377; 85.0%) and men (N = 15,836; 51.1%). During the period described in the report, the number of deaths reached 1285/31,017 (4.1%). When analyzing the deaths, the most representative age groups were those of children under 1 year old (505/1285; 39.9%), from 1 to 4 years old (178/1285; 13.8%), and the elderly from 60 to 79 years old (150/1285; 11.6%). The Indigenous individuals from this ethnic group presented a child death rate ~ 1.5 to 3.5 higher than that of the total Indigenous population in the country. Regarding the child death rate, the neonatal component represented 57.8% of the deaths and, in 2022, 93.0% of the pregnant women had less than six prenatal appointments. This population shows a high number of deaths due to preventable causes (N = 538) and cases of illnesses associated with hygiene and sanitation, for example (N = 35,103 cases/notifications). As for vaccination, the full vaccination scheme targeting children below 5 years old has not been met since 2018. CONCLUSION: In the Indigenous population of the Yanomami ethnic group, a high number of deaths was observed, which affected mainly individuals under 1 year old. Among the factors associated with the deaths, mainly in children under 5 years old, most cases have preventable causes, which could be reduced by proper action promoting their health and preventing diseases.

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Introducción: La COVID-19 provocó cambios laborales e influyó en el comportamiento de los docentes universitarios. Objetivo: Describir el bienestar y la salud ocupacional de profesores universitarios en la formación investigativa mediante el teletrabajo. Métodos: Se realizó un análisis sistemático mediante la metodología PRISMA que incluyó todo el año 2022 y los primeros meses del 2023. Con los artículos incluidos se aplicó la herramienta de búsqueda bibliográfica en línea Litmaps. Asimismo, se empleó un cuestionario y posteriormente la escala de Likert. El instrumento se validó con el coeficiente alfa de Cronbach y se consideró la prueba t de una muestra para probar como hipótesis descriptiva si el bienestar y la salud ocupacional desde la formación investigativa en docentes universitarios mediante el teletrabajo eran satisfactorios. Resultados: En el estudio, 41,2 % de los artículos de revisión e investigación seleccionados con la metodología PRISMA correspondieron al año 2022; sin embargo, el 50,0 % de los artículos semillas fueron del 2023, donde su análisis mapa indicó que no hubo citas de correspondencias. En cuanto al resultado de la valoración con la escala de Likert y luego con la prueba de hipótesis, se obtuvo insatisfacción en los profesores respecto a la formación investigativa mediante el teletrabajo. Conclusiones: Existió insatisfacción respecto al bienestar y la salud ocupacional para la formación investigativa desde el teletrabajo porque los docentes universitarios consideraban que las condiciones laborales no fueron favorables.

Introduction: COVID-19 caused job changes and influenced the behavior of university professors. Objective: To describe well-being and occupational health in research training of university professors through teleworking. Methods: A systematic analysis was carried out using the PRISMA methodology that included the entire year 2022 and the first months of 2023. The online bibliographic search tool Litmaps was applied to the included articles. Likewise, a questionnaire was used and subsequently the Likert scale. The instrument was validated with Cronbach's alpha coefficient and the one-sample T-test was considered as a descriptive hypothesis whether well-being and occupational health from research training in university professors through teleworking were satisfactory. Results: In the study, 41.2% of the review and research articles selected with the PRISMA methodology corresponded to the year 2022; however, 50.0% of the seed articles were from 2023, where their map analysis indicated that there were no citations of correspondences. Regarding the result of the assessment with the Likert scale and then with the hypothesis test, dissatisfaction was obtained among professors concerning research training through teleworking. Conclusions: There was dissatisfaction regarding well-being and occupational health for research training through teleworking because university professors considered that working conditions were not favorable.

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Resumo A pandemia de COVID-19 teve um imenso impacto nas condições de vida e trabalho de toda a população do país, impactando de modo diferenciado e mais intenso os grupos considerados vulneráveis. O objetivo deste artigo é apresentar um panorama da evolução da pandemia no país segundo os boletins do Observatório Covid-19 Fiocruz, no período entre as declarações de início e de encerramento da Emergência em Saúde Pública de Importância Nacional (ESPIN), fevereiro de 2020 a abril de 2022. Foram utilizados diversos dos indicadores adotados nos 69 boletins publicados para a análise da pandemia, como casos e óbitos por SRAGs e COVID-19, grupos etários, taxas de ocupação de leitos UTI e vacinação, entre outros. A análise da evolução foi organizada entre anos e fases da pandemia, procurando destacar o que caracterizou cada momento. A declaração de encerramento da ESPIN no Brasil coincide com as discussões acerca da transição de pandemia para a endemia, sem que isso represente a eliminação do vírus, das infecções e da doença, colocando-se os desafios de avanços nos processos de vacinação no Brasil e no mundo e da convivência com cenários que poderão exigir a adoção de medidas de proteção temporárias em períodos epidêmicos e de maior risco para grupos vulneráveis.

Abstract The COVID-19 pandemic had a significant impact on the living and working conditions of the entire population of Brazil, having a different and more intense effect on groups considered to be vulnerable. The objective of this article is to present an overview of the evolution of the pandemic in the country according to the bulletins of the Covid-19 Fiocruz Observatory in the period between the declarations of the beginning and end of the Public Health Emergency of National Concern (ESPIN, in Portuguese), February 2020 to April 2022. Several of the indicators adopted in the 69 bulletins published for the analysis of the pandemic were used, such as cases and deaths due to SARIs and COVID-19, age groups, % of occupancy of ICU beds, and vaccination, among others. The evolution analysis was organized between years and phases of the pandemic, seeking to highlight what characterized each moment. The closing statement of ESPIN in Brazil coincides with the discussions on the transition from a pandemic to an endemic scenario, without this representing the elimination of the virus, infections, and disease, posing the challenges of advances in vaccination processes in Brazil and around the world, as well as living with scenarios that may require the adoption of temporary protection measures in epidemic periods and periods of greater risk for vulnerable groups.

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Public health emergencies are extraordinary events of disease spread, with health, economic, and social consequences, which require coordinated actions by governments and society. This work aims to analyze scopes, application possibilities, challenges, and gaps of decision support frameworks in PHE management, using the components of the Health Emergency and Disaster Risk Management Framework (H-EDRM) and the Preparedness, Prevention, Response and Recovery Model (PPRR Model), providing guidelines for the development of new models. A systematic literature review was carried out using the Web of Science, Scopus, and Pubmed knowledge databases on studies published between 2016 and 2023, and thirty-six articles were selected. The outcomes show a concentration of frameworks on short-term emergency response operations, with a limited emphasis on the political and strategic components that drive actors and responsibilities. Management prioritizes monitoring, evaluation, and information management frameworks. However, the models need to overcome the challenges of multisectoral and interdisciplinary action, different levels of decisions and actors, data sharing, and development of common platforms of evidence for decisions fitted to the various emergencies.

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Monkeypox virus (MPXV) is an emerging zoonotic virus that belongs to the Orthopoxvirus genus and presents clinical symptoms similar to those of smallpox, such as fever and vesicular-pustular skin lesions. However, the differential diagnosis between smallpox and monkeypox is that smallpox does not cause lymphadenopathy but monkeypox generates swelling in the lymph nodes. Since the eradication of smallpox, MPXV has been identified as the most common Orthopoxvirus to cause human disease. Despite MPXV being endemic to certain regions of Africa, the current MPXV outbreak, which began in early 2022, has spread to numerous countries worldwide, raising global concern. As of the end of May 2023, over 87,545 cases and 141 deaths have been reported, with most cases identified in non-endemic countries, primarily due to human-to-human transmission. To better understand this emerging threat, this review presents an overview of key aspects of MPXV infection, including its animal reservoirs, modes of transmission, animal models, epidemiology, clinical and immunological features, diagnosis, treatments, vaccines, and prevention strategies. The material presented here provides a comprehensive understanding of MPXV as a disease, while emphasizing the significance and unique characteristics of the 2022 outbreak. This offers valuable information that can inform future research and aid in the development of effective interventions.

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Purpose: The study aimed to determine the association between family support and coping strategies of people diagnosed with COVID-19. Methods: The study was analytical and cross-sectional. The sample consisted of 500 participants who were selected by non-probabilistic and snowball sampling and included residents of both sexes who belonged to the city of Lima, with a diagnosis of COVID-19, who lived with relatives, and who accepted to participate in the research. For data collection, the scales "family support" and "Coping and Adaptation Process-Coping Adaptation Processing Scale (CAPS)" were used. The technique used was the survey through the home visit and the questionnaire instrument. To measure the relationship of the study variables, binary logistic regression was chosen, considering coping strategies as the dependent variable and socio-demographic data and family support as independent variables. Results: Of the 500 participants, 50.4% were women, and 49.6% were men. The results revealed that most participants presented a high capacity for coping strategies and high perceived family support (97.2% and 81%, respectively). In the bivariate analysis, socio-demographic aspects and family support and their dimensions were related to high or low capacity for coping strategies. Significant differences were verified between marital status (p=0.026), having children (p=0.037), family support (p=0.000), and its dimensions with coping strategies. Finally, the multivariate analysis found that people with COVID-19 who perceived high family support were 33.74 times (95% CI: 7266-156,739) more likely to have a high capacity for coping strategies. Conclusion: Therefore, it is necessary to promote the development of parental and family support skills in the face of the health emergency caused by COVID-19.

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Este artículo describe los perfiles de personalidad de 95 adolescentes de la ciudad del Alto de La Paz. Los datos surgen del proceso empírico realizado en periodo de emergencia sanitaria por la pandemia por COVID -19. Los adolescentes en este contexto buscan nuevas e innovadoras maneras de afrontar esta realidad. Para eso se proyectan a partir de sus cualidades, habilidades, competencias y características que permiten la búsqueda de un proyecto de vida o la elección de una carrera universitaria. Se utilizó técnicas de investigación cuantitativa (Cuestionario Big Fives o Cinco Grandes) para reconocer los índices en cada dimensión, sub dimensión y escala de distorsión de la personalidad y se realizó un abordaje cualitativo en el reconocimiento de los perfiles de personalidad. Se observó que existe una tendencia mayor de adolescentes con predisposición a ser creativos e investigadores y no así realistas, sociales y dirigentes. La conclusión es que los datos permitirán a los adolescentes una perspectiva distinta en la elección de carreras universitarias convencionales.

This article describes the personality profiles of 165 adolescents from the City of Alto de La Paz. In times of health emergency it is a problem to set medium-term objectives. Teenagers must seek new and innovative ways to deal with this reality. For this, it is necessary to recognize the qualities, skills, competencies and characteristics of adolescents who are looking for a life project or the choice of a university career. Quantitative research techniques (Big Fives or Big Five Questionnaire) were used to recognize the levels in each dimension, sub-dimension and personality distortion scale and a qualitative approach was carried out in the recognition of personality profiles. It was observed that there is a greater tendency of adolescents with a predisposition to be creative and investigative and not so realistic, social and leaders. The conclusion is that the data will allow adolescents a different perspective in the choice of conventional university careers.

Este artigo descreve os perfis de personalidade de 165 adolescentes da cidade de Alto de La Paz. Em tempos de emergência sanitária é um problema estabelecer objetivos de médio prazo. Os adolescentes devem buscar formas novas e inovadoras de lidar com essa realidade. Para isso, é necessário reconhecer as qualidades, habilidades, competências e características dos adolescentes que buscam um projeto de vida ou a escolha de uma carreira universitária. Técnicas de pesquisa quantitativa (Big Fives ou Big Five Questionnaire) foram utilizadas para reconhecer os níveis em cada dimensão, subdimensão e escala de distorção de personalidade e uma abordagem qualitativa foi realizada no reconhecimento de perfis de personalidade. Observou-se que há uma maior tendência de adolescentes com predisposição a serem criativos e investigativos e não tão realistas, sociais e líderes. A conclusão é que os dados permitirão aos adolescentes uma perspectiva diferente na escolha das carreiras universitárias convencionais.

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Introducción:el abordaje integral de la salud mental es uno de los retos del país en salud pública, dado que la población colombiana ha presentado un deterioro en ese aspectoen los últimos veinte años de acuerdo con el documentoCONPES 3992del2020.Objetivo:Caracterizar los registros individuales de prestación de servicios en atención desalud mental en unainstitución prestadora de servicios enBogotá,Colombia, entre el 2001 y el2017. Métodos:estudio descriptivo trasversal. Se usaron los registros individuales de prestación de servicios como fuente de informacióny se tuvo en cuentaclasificación internacional de enfermedades (CIE-10) Entotal de registros RIPS en salud mental, por equipo interdisciplinario: médico general, médico psiquiatra, enfermería, psicología, trabajo social y terapia ocupacional. Resultados:se analizaron 2.360.295 registros individuales de prestación de servicios en salud mental de la institución seleccionada. Según los registros,el promedio de edad de las personas atendidas era de 47 añosypredominó el sexo femenino con el 52,5%. Los servicios utilizados fueronhospitalización (49,82%), consulta externa (43,42%), urgencias (4,54%)y hospital de día (0,39%). Elmayor número de registros (64,47%) se presentó en el grupo entre los 18 y 59 años de edad; seguido del grupo de 60 años o más (28,50%)y de menores de 18 años (7,03%). Los grupos de diagnóstico principales fueron trastorno psicótico con el 33,38%,depresióncon el 15,39%y ansiedad con el 13,71%. Conclusiones:Son las mujeres quienes más utilizan el servicio (52.5%). Es la hospitalización el servicio más utilizado (49.82%). Son los adultos entre 18 y 59 años quienes más utilizan los servicios (64.47%). Se observa un progresivo incremento en el número de atenciones. Los trastornos mentales severos esquizofrenia y bipolar son los másatendidos (33.38%) seguidos de trastornos de depresión y ansiedad (29%). Las enfermedades medicas generales se presentaron en el (10.95%)de las atenciones.

Introduction: The comprehensive approach to mental health is one of the country's public health challenges, as the Colombian population has deteriorated in this area over the past twenty years, according to the CONPES Document 3992, 2020. Objective:To characterize the individual mental health service delivery records at a service provider institution in Bogota, Colombia, between 2001 and 2017. Methods:Descriptive cross-sectional study. Individual service delivery records were used as a source of information, and the International Classification of Diseases (ICD-10) was considered. Total mental health RIPS by interdisciplinary team: general practitioner, psychiatrist, nurse, psychologist, social worker, and occupational therapist. Results:A total of 2,360,295 individualmental health service delivery records from the selected institution were analyzed. According to the records, the average age of the patients was 47 years, and females predominated with 52.5% of the patients. Inpatient (49.82%), outpatient (43.42%), emergency room (4.54%), and day hospital (0.39%) services were used. The highest number of records (64.47 %) were found among the 18-59 years age group, followed by the 60+ year age group (28.50 %) and those under 18 years of age (7.03 %). The main diagnostic groups were psychotic disorder (33.38%), depression (15.39%), and anxiety (13.71%). Conclusions:Women are the main users of the service (52.5%). Hospitalization is the service most frequently used (49.82%). Adults between the ages of 18 and 59 use the services the most (64.47%). There has been a progressive increase in the number of attendances. Severe schizophrenia and bipolar mental disorders are the most treated (33.38%), followed by depression and anxiety (29%). General medical conditions were present in 10.95% of attendances

Introdução:a abordagem integral da saúde mental é um dos desafios do país em saúde pública, visto que a população colombiana tem apresentadouma deterioração neste aspecto nos últimos vinte anos de acordo com o documento Conpes 3992de 2020. Objetivo:Caracterizar os registros individuais de prestação de serviços em saúde mental em uma instituição prestadora de serviços em Bogotá, Colômbia, entre 2001 e 2017. Métodos:estudo descritivo transversal. Usaram-se os registros individuais de prestação de serviços como fonte de informação e considerou-sea classificação internacional de doenças (CID-10). No total de registros RIPS em saúde mental, por equipe interdisciplinar: clínico geral, psiquiatra, enfermagem, psicologia, serviço social e terapia ocupacional. Resultados:Foram analisados 2.360.295 prontuários individuais de prestação de serviço de saúde mental da instituição selecionada. De acordo com os registros, a média de idade das pessoas atendidas foi de 47 anos e o sexo feminino predominou com 52,5%. Os serviços utilizados foram internação (49,82%), ambulatorial (43,42%), emergência (4,54%) e hospital-dia (0,39%). O maior número de registros (64,47%) foi apresentado no grupo entre 18 e 59 anos; seguido pelo grupo de 60 anos ou mais (28,50%) e os menores de 18 anos(7,03%). Os principais grupos diagnósticos foram transtorno psicótico com 33,38%, depressão com 15,39% e ansiedade com 13,71%. Conclusões:As mulheres são as que mais utilizam o serviço (52,5%). A internação é o serviço mais utilizado (49,82%). Os adultosentre 18 e 59 anos são os que mais utilizam os serviços (64,47%). Observa-se um aumento progressivo no número de atenções. Os transtornos mentais graves esquizofrenia e bipolaridadesão os mais atendidos (33,38%) seguidos de depressão e transtornos de ansiedade (29%). Doenças médicas gerais estiveram presentes em (10,95%) dos atendimentos

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Research assessing the trend in online search activity on monkeypox (mpox) and the correlation with the mpox epidemic at the global and national level is scarce. The trend of online search activity and the time-lag correlations between it and daily new mpox cases were estimated by using segmented interrupted time-series analysis and Spearman correlation coefficient (rs), respectively. We found that after the declaration of a Public Health Emergency of International Concern (PHEIC), the proportion of countries or territories with increasing changes in online search activity was lowest in Africa (8.16%, 4/49), and a downward trend in online search activity was highest in North America (8/31, 25.81%). The time-lag effect of global online search activity on daily new cases was significant (rs = 0.24). There were eight countries or territories with significant time-lag effect; the top three countries or territories were Brazil (rs = 0.46), United States (rs = 0.24), and Canada (rs = 0.24). Interest behavior in mpox was insufficient, even after the declaration of PHEIC, especially in Africa and North America. Online search activity could be used as an early indicator of the outbreak of mpox at the global level and in epidemic countries.

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In Brazil, the epicenter of the Zika crisis, brown, black, and indigenous poor women living in municipalities with scarce resources were disproportionally affected. The gendered consequences of the epidemic exposed how intersectional lenses are central to understand the impact of public health emergencies in the lives of women and girls. The demand for Zika-affected children and women to be research participants is relevant for an ethical analysis of participant protection procedures during a crisis. We investigated how women experienced research participation by analyzing their narratives. Two-year-long longitudinal qualitative study in Brazilian sites located in the epidemic's epicenter was performed using mixed methods: ethnography with women from two distinct states and individual semi-structured interviews with five women in different Zika-affected states, four of which were community leaders. All women in the study were mothers or grandmothers of Zika-affected children. Thematic analysis was used for data evaluation. Women perceived being pressured to participate in research and a lack of benefit sharing. Structural determinants of gender inequality, such as its effect on power distribution, were found to impact research participant protection. Formal procedures for research protocols approvals were insufficient in protecting participants because these instruments were unable to account for structural aspects. Communitarian mobilization, through WhatsApp groups, was found to be an important mechanism to create conditions to challenge oppressive structures. Strengthening public health, effective community-based participation in research planning and implantation of ethical strategies that promotes gender equality can have transformative effect on unequal power structures and promote participant protection.

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Resumo Este artigo aborda a participação do BRICS na produção e distribuição de vacinas contra covid-19 durante 2020 e 2021, e o compromisso com a priorização do acesso aos países do Sul Global. Faz, ainda, uma reflexão sobre como o grupo lidou com os desafios do compartilhamento de tecnologias e do empoderamento econômico dos países periféricos, sinalizando a disputa de espaço entre a diplomacia da vacina e os interesses econômicos das nações. A análise se deu com base em relatórios institucionais, dados documentais jornalísticos e científicos, e no diálogo destes com os conhecimentos da Diplomacia da Saúde e da Cooperação Internacional em Saúde, demonstrando a complexidade e os desafios do mundo após o surgimento do vírus SARS-CoV-2 e suas variantes.

Abstract This study describes the participation of the BRICS in the production and distribution of COVID-19 vaccines in 2020 and 2021 and its commitment to prioritizing access by the countries of the Global South. It also reflects on how the Group dealt with the challenges of technology sharing and the economic empowerment of peripheral countries, signaling the space dispute between vaccine diplomacy and the economic interests of nations. This analysis was based on institutional reports, journalistic and scientific documentary data, and their dialogue with the knowledge of Health Diplomacy and International Health Cooperation, showing the complexity and challenges of the world after the emergence of the SARSCoV-2 virus and its variables.

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En mayo 2023, la OMS levanta la declaratoria de emergencia sanitaria internacional por Covid-19, pero Bolivia continúa manteniendo la declaratoria de emergencia sanitaria nacional. Objetivo: describir la situación epidemiológica por Covid-19 en Bolivia en comparación a los países sudamericanos. Metodología: Estudio observacional de tipo ecológico; con datos agregados a nivel departamental y nacional, provenientes de los reportes del Ministerio de Salud de Bolivia y la OMS. Se reportan frecuencias absolutas, porcentajes y tasas de incidencia, mortalidad, letalidad y las coberturas de vacunación, desagregadas por países, departamentos. Resultados: A nivel sudamericano, Bolivia ocupa el 6to lugar en el número de casos confirmados (n=1,198,404); 7mo en número de fallecidos (n=22,383), 5to en letalidad (1,9%), y penúltimo en cobertura de vacunación (52,08%). En Bolivia; se observa una tendencia decreciente de casos entre la primera (n=144,592) y 6ta ola (n=88,859); Santa Cruz reportó más casos (n=4037.908) y Pando el más bajo (n=15,081). La tasa de incidencia fue más alta en Tarija y más baja en Potosí. La tasa de Letalidad fue mayor en la primera ola (6,20%) y más baja en la sexta ola (0,20%). La cobertura de vacunación con al menos una dosis fue mayor en Tarija (75,10%), y la más bajas en Beni (57,10%). Conclusión: Bolivia presenta un descenso significativo en el número total de casos nuevos reportados, con disminución de la tasa de mortalidad y letalidad; sin embargo, las coberturas de vacunación en esquema completo y dosis de refuerzo siguen siendo una de las más bajas a nivel sudamericano.

In May 2023, the WHO lifts the declaration of an international health emergency due to Covid-19, but Bolivia continues to maintain the declaration of a national health emergency. Objective: describe the epidemiological situation by Covid-19 in Bolivia compared to South American countries. Methodology: Observational study of ecological type was conducted; with aggregated data at the departmental and national level, from the reports of the Bolivian Ministry of Health and the WHO. Absolute frequencies, percentages, and rates of incidence, mortality, lethality, and vaccination coverage are reported, broken down by country and department. Results: In the South American context, Bolivia ranks 6th in the number of cumulative confirmed cases (n=1,198,404); 7th in the number of deaths (n=22,383), 5th in lethality (1.9%), and 9th in vaccination coverage (52.08%) from ten countries. A decreasing trend is observed in Bolivia, between the first epidemic wave (n=144,592) to the 6th wave (n=88,859); Santa Cruz reported the most cases (n=4037,908) and Pando the lowest (n=15,081). The incidence rate was highest in Tarija and lowest in Potosí. The fatality rate was higher in the first wave (6.20%) and lower in the sixth wave (0.20%). Vaccination coverage with at least one dose was higher in Tarija (75.10%), and the lowest in Beni (57.10%). Conclusion: Bolivia presents a significant decrease in the total number of new cases reported, with a decrease in the mortality and lethality rate; however, full-schedule vaccination coverage and booster doses continue to be one of the lowest in South America.

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Resumo Nesta entrevista, Sonia Guajajara, coordenadora executiva da Articulação dos Povos Indígenas do Brasil (APIB), aborda as análises e estratégias desenvolvidas pelo movimento indígena para o enfrentamento da pandemia da COVID-19. Entre os pontos destacados, estão as estratégias de comunicação, vigilância e monitoramento da COVID-19, o apoio aos territórios indígenas, as iniciativas no Legislativo e no Judiciário, a incidência internacional e a articulação com a academia. Torna-se evidente o importante protagonismo do movimento indígena nas ações de contenção da emergência sanitária e na defesa dos direitos dos povos indígenas, em uma conjuntura de embate com o governo federal e de retrocessos nas políticas públicas.

Abstract In this interview, Sonia Guajajara, the executive coordinator of the Brazil's Indigenous Peoples Articulation (APIB), addresses the analyzis and strategies developed by the Indigenous movement to face the COVID-19 pandemic. Among other topics, she highlights some of the movement's strategies concerning communication, surveillance, and the monitoring of COVID-19, as well as its actions to support Indigenous territories, the initiatives carried out in the Legislative and Judiciary realms, the movement's international incidence, and its articulation with academia. Sonia shows the important role played by the Indigenous movement to control the health emergency and to defend the rights of the Indigenous peoples, in the framework of intense conflicts with the federal government and setbacks in public policies.

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Resumo O estudo da definição de agendas e prioridades da saúde global tem sido, nos últimos anos, uma das prioridades de uma literatura crítica que visa identificar as dimensões políticas da governança global em saúde, e que enfatiza os pontos de tensão, exclusão e desigualdade. O presente ensaio se posiciona nesta leitura crítica da saúde global, focando a construção da categoria de emergência de importância internacional. Considerando em específico o caso do surto de zika e de síndromes congênitas no Brasil, em 2016, explora as condições que possibilitam a construção de uma emergência. Questionamos os fatores e condições em torno desse evento de saúde pública que eventualmente foram considerados no processo decisório, e que vão além dos dados materiais mais objetivos relativos à epidemiologia do zika, à sua morbi-mortalidade ou à sua associação com as malformações congênitas. Concluímos que o contexto securitário e a crescente importância do risco na saúde global são condições importantes para entender as declarações de emergência.

Abstract The study of global health agenda-setting and issue-prioritization has been one of the key aspects of a critical literature that, in recent years, has aimed to identify the political dimensions of global health governance and to shed light on points of tension, exclusion, and inequality. This essay speaks to this critical global health literature, focusing on the construction of the category of emergencies of international concern. Considering the case of the outbreak of zika and congenital syndrome in Brazil in 2016, it explores the conditions enabling the construction of an emergency. We question the factors and conditions around this public health event that were considered during the decision-making process and that transcended material, more objective data regarding zika's epidemiology, its morbimortality, or its association with congenital malformations. We conclude that the securitized context and the growing relevance of risk to global health are important conditions for understanding emergency declarations.

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La pandemia de COVID-19 pone en evidencia la importancia de los aspectos psicológicos y de salud mental para la prevención y afrontamiento de sus consecuencias. En este contexto se requiere de un modelo de Seguridad Psicológica (SP) que fundamente teórica y metodológicamente su gestión en una situación de emergencia sanitaria. El problema de la SP, visto desde una perspectiva transdisciplinar, intercepta aspectos relacionados con la epistemología y la sociología de la ciencia: análisis crítico del concepto a la luz de los aportes de otras disciplinas; relaciones entre el nivel de acceso al conocimiento y el funcionamiento de los equipos de trabajos; y contradicción entre la gestión neoliberal de la pandemia y la necesidad de un afrontamiento humanista. El objetivo del artículo es analizar, desde la perspectiva sociológica y epistemológica, la SP del personal de la salud en emergencias sanitarias, para lo cual se desarrolló una revisión narrativa. Como resultado, se presentan las reflexiones desarrolladas acerca del tema estructuradas en dos momentos: la aproximación crítica a la epistemología del concepto de SP y el impacto de la SP en los equipos de trabajo visto desde la concepción de la sociedad del conocimiento. Se enfoca la SP como un campo transdisciplinario y se valoran los antecedentes y aportes de otras disciplinas para su empleo en situaciones de emergencia y desastres. También se contrasta el afrontamiento a la COVID-19 desde la gestión neoliberal con su afrontamiento humanista. Finalmente, se presenta una nueva perspectiva de la SP para la gestión de la salud mental del personal de la salud involucrado en la respuesta a emergencias y desastres

The COVID-19 pandemic highlights the importance of psychological and mental health aspects for preventing and coping with its consequences. In this context, a model of Psychological Safety (PS) is required that theoretically and methodologically bases its management in a health emergency situation. The problem of PS, seen from a transdisciplinary perspective, intercepts aspects related to the epistemology and sociology of science: the critical analysis of the concept in light of the contributions of other disciplines; the relationships between the level of access to knowledge and the functioning of work teams and the contradiction between the neoliberal management of the pandemic and the need for a humanistic approach. The objective of the article is to analyze, from the sociological and epistemological perspective, the PS of health personnel in health emergencies, for which a narrative review was developed. As a result, the reflections developed on the subject structured in various moments are presented: the critical approach to the epistemology of the concept of PS; the impact of PS on work teams seen from the conception of the knowledge society. PS is approached as a transdisciplinary field and the antecedents and contributions of other disciplines are valued for its use in emergency situations and disasters. The coping with COVID-19 is also contrasted from that of neoliberal management with its humanistic coping. Finally, a new perspective of the PS is presented for the management of the mental health of the health personnel involved in the response to emergencies and disasters

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Introducción: La pandemia de la COVID-19 es una emergencia de salud pública que ha modificado sustancialmente la educación médica por pasar de una modalidad presencial a una en línea. Objetivo: Evaluar la Satisfacción Académica antes y durante la pandemia de la COVID-19 en una muestra de estudiantes universitarios de ciencias de la salud del Perú. Material y Método: Estudio observacional, de diseño comparativo y corte transversal. Se utilizó una ficha sociodemográfica ad hoc con preguntas; ¿Cómo calificarías tu rendimiento académico en la universidad? Antes de la pandemia, habías llevado cursos virtuales, ¿su conexión de internet en su casa es?, ¿ha desaprobado algún curso el semestre pasado?, ¿ocupación? Y la Escala de Satisfacción Académica (ESA) compuesta por ocho ítems. Todas las preguntas fueron aplicadas mediante un formulario, que se encontró vigente durante dos semanas en la plataforma virtual de la universidad y fue realizado en junio de 2019 (primera evaluación) y agosto del 2020 (segunda evaluación). Resultados: Dentro de las variables sociodemográficas evaluadas la mala calidad de la conectividad a internet (dCohen = -0,65) y autoevaluación rendimiento como muy alto (dCohen = -0,72) presentan diferencias moderadas entre 2019 y 2020. Conclusiones: Los cambios en la Satisfacción Académica del estudiante de Ciencias de la Salud durante la emergencia sanitaria por la COVID-19, tienen una fluctuación considerable cuando la conectividad del internet es mala y el estudiante se evalúa a sí mismo como una persona con alto rendimiento, variables que pueden ser tenidas en cuenta al momento de diseñar estrategias curriculares en estudiantes de Ciencias de la Salud(AU)

Introduction: The COVID-19 pandemic is a public health emergency that has substantially modified medical education from face-to-face to online teaching modalities. Objective: To evaluate academic satisfaction before and during the COVID-19 pandemic in a sample of university students of health sciences in Peru. Material and Methods: Observational, cross-sectional, and comparative study. An ad hoc sociodemographic form was used; the following questions were included: How would you rate your academic performance at the university? Had you taken any virtual courses before the pandemic? Do you have internet connection at home? Did you fail any course last semester? What is your occupation? The Academic Satisfaction Scale (ASE), which was composed of eight items, was also used. All the questions were asked using a form that was valid on the virtual platform of the university for two weeks and applied in June 2019 (first evaluation) and August 2020 (second evaluation). Results: Among the sociodemographic variables evaluated, the poor quality of internet connectivity (Cohen's d = -0,65) and self-assessment of performance as very high (Cohen's d = -0,72) show moderate differences between 2019 and 2020. Conclusions: The academic satisfaction among health sciences students during the COVID-19 health emergency change considerably when the Internet connectivity is poor and the students evaluate themselves as high achievers, variables that can be considered when designing curricular strategies for health sciences students(AU)

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OBJECTIVE: The COVID-19 protective motivation scale (EMP-COVID-19) has been developed for the assessment of protective motivation. This study aims to examine the psychometric properties of the EMP-COVID-19 for its application in the Peruvian community. METHODS: This is an observational, cross-sectional, instrumental design study, 483 adults (≥18 years) participated in the study, in 2 samples of 81 and 402 participants from the different macro-regions of Peru through an online survey using non-probabilistic sampling. Content validation was performed through expert judgment. Exploratory factor analysis (EFA) to evaluate the factor model of the EMP-COVID-19 was performed with the first sample. The confirmatory factor analysis (CFA) to verify the goodness of fit of the analysis found in the EFA was performed with the second sample. The examination of convergent and discriminant validity included peer evaluations of each EMP-COVID-19 dimension. Finally, the reliability of the instrument was evaluated using Cronbach's Alpha coefficient. RESULTS: The 3-factor related model presents better fit indices (CFI = 0.99; TLI = 0.99; RMSEA = 0.077 [90% CI 0.069-0.085]) versus a unidimensional model (CFI = 0.91; TLI = 0.90; RMSEA = 0.206 [90% CI 0.199-0.213]). The scale present convergent and discriminant validity in all the dimensions Threat Appraisal (AVE = .57), Coping Appraisal (AVE = .81), and Response Costs (AVE = .67). The Coping Appraisal (α = .97; ω = .97), Threat Appraisal (α = .88; ω = .74), and Response Costs (α = .80; ω = .76) dimensions were also found to have adequate reliability indices. CONCLUSIONS: The EMP-COVID-19 scale demonstrated adequate reliability and validity based on internal structure in the study sample.

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