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1.
Nutrients ; 16(12)2024 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-38931299

RESUMO

Carpal tunnel syndrome (CTS) is the most common cause of peripheral compressive neuropathy and consists of compression of the median nerve in the wrist. Although there are several etiologies, idiopathic is the most prevalent origin, and among the forms of treatment for CTS, conservative is the most indicated. However, despite the high prevalence in and impact of this syndrome on the healthcare system, there are still controversies regarding the best therapeutic approach for patients. Therefore, noting that some studies point to vitamin D deficiency as an independent risk factor, which increases the symptoms of the syndrome, this study evaluated the role of vitamin D supplementation and its influence on pain control, physical examination and response electroneuromyography to conservative treatment of carpal tunnel syndrome. For this, the sample consisted of 14 patients diagnosed with CTS and hypovitaminosis D, who were allocated into two groups. The control group received corticosteroid treatment, while the experimental group received corticosteroid treatment associated with vitamin D. Thus, from this study, it can be concluded that patients who received vitamin D, when compared to those who did not receive it, showed improvement in the degree of pain intensity, a reduction in symptom severity and an improvement in some electroneuromyographic parameters.


Assuntos
Síndrome do Túnel Carpal , Eletromiografia , Deficiência de Vitamina D , Vitamina D , Humanos , Síndrome do Túnel Carpal/tratamento farmacológico , Vitamina D/uso terapêutico , Feminino , Deficiência de Vitamina D/tratamento farmacológico , Deficiência de Vitamina D/complicações , Masculino , Pessoa de Meia-Idade , Adulto , Resultado do Tratamento , Suplementos Nutricionais , Corticosteroides/administração & dosagem , Nervo Mediano/fisiopatologia , Idoso
2.
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;57: e00802, 2024. graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1535374

RESUMO

ABSTRACT Neural leprosy, which is characterized by nerve involvement without visible skin lesions, presents a diagnostic challenge. This case report examined the significance of diverse diagnostic modalities in the identification of pure neural leprosy. A 28-year-old patient with symptoms of edema, pain, paresthesia, and diminished sensitivity in the lower limbs underwent various tests. A stilt skin smear yielded negative results on bacilloscopy, whereas a Fast ML Flow leprosy test and electroneuromyography supported the diagnosis. This discussion highlights the importance of accessible methods for early investigation. This study emphasizes the multidisciplinary approach and value of the Fast ML Flow leprosy test and electroneuromyography for diagnosing neural leprosy.

3.
Front Med (Lausanne) ; 10: 1304131, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38259847

RESUMO

Introduction: Leprosy is one of the most common infectious cause of peripheral neuropathy in the world and can lead to sequelae and physical disabilities. Electroneuromyography (ENMG) is the gold-standard test for evaluating neural impairment, detecting from subclinical abnormalities to advanced lesions. This study aims to describe the electroneuromyographic findings in patients with leprosy, according to their clinical forms. Methods: The study is a retrospective observational analysis of the medical records of patients with leprosy, of a National Reference Center of Sanitary Dermatology and Leprosy in Brazil between 2014 and 2022. 513 patients underwent ENMG at leprosy diagnosis and also underwent a clinical, serological and molecular evaluation of the disease. Results: The electroneuromyographic findings showed 2,671 altered nerves, with an average of 6.9 (±5.1) altered nerves per patient. The most affected sensory nerves were the superficial peroneal (25.0%; 413/1649), sural (15.1%; 397/2627) and ulnar (13.8%; 363/2627), with average of 4.3 (±3.2) affected sensory nerves per patient. The most affected motor nerves were the ulnar (33.1%; 338/1022) and common peroneal (12.1%; 319/2627), with average of 2.6 (±2.5) motor nerves affected per patient. 126 patients presented normal ENMG and, among the 387 with abnormalities in the exam, 13.2% (51/387) had mononeuropathy and 86.8% (336/387) had multiple mononeuropathy. Axonal involvement was more frequent in primary neural leprosy, borderline-tuberculoid, borderline-lepromatous and lepromatous forms. Discussion: Our findings support that leprosy is a spectral disease, characterized by a balance between host immunity and bacillary load. Therefore, the impairment and electroneuromyographic characteristics are distinct and may vary according to the clinical form.

4.
Indian J Dermatol Venereol Leprol ; 88(5): 641-644, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34951937

RESUMO

Introduction Neuropathic pain is a common and disabling late complication of leprosy. We investigated the clinical and electrophysiological characteristics of neuropathic pain in leprosy patients by evaluating nerve conduction, sympathetic skin response (SSR) and A-waves. Methods Twenty one leprosy patients with neuropathic pain validated by the Douleur Neuropathique en 4 (DN4)Questionnaire were selected for study. Pain intensity was measured by the visual analog scale. Demographic and clinical data were collected for all patients. Clinical data included appraisal of the median, ulnar, radial, tibial and common peroneal nerves, assessment of the sympathetic skin response and conventional electrophysiological recordings. Results Among all electroneuromyographic presentations, multifocal mononeuropathy was still the most prevalent. Sensory loss was observed more frequently than motor deficits. As most patients presented advanced clinical forms of leprosy and were under treatment, this high mean was found and the ulnar nerve was most frequently affected. The sympathetic skin response was absent in 16 patients. Higher DN4 Questionnaire scores were observed in women and in those receiving corticosteroid therapy. These inferences are possible to be made, but our study's limitations don't allow us to be certain about it. The statistical significance found only permits us to evidence what we related on the textual part of the study. Limitations The small number of patients studied, the lack of sophisticated diagnostic methods for leprosy, as well as the difficulties in assessing nerve conduction were the main limitations of this study. Conclusion The neurophysiological and clinical findings in leprous neuropathy were modest despite the conspicuous neuropathic pain. Although electrophysiological studies are a vital tool to verify nerve damage, variations in the clinical presentation of leprosy neuropathic pain render the diagnosis challenging. Further studies are needed to describe the neurophysiological evolution of this disease.


Assuntos
Hanseníase , Neuralgia , Estudos Transversais , Feminino , Humanos , Hanseníase/complicações , Hanseníase/diagnóstico , Condução Nervosa/fisiologia , Neuralgia/diagnóstico , Neuralgia/epidemiologia , Neuralgia/etiologia , Estudos Prospectivos
5.
ACM arq. catarin. med ; 50(1): 137-143, 13/04/2021.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1354494

RESUMO

A Síndrome de Parsonage-Turner (SPT) é uma doença rara que acomete a musculatura da cintura escapular, acarretando hipotrofia muscular e grande limitação funcional. A etiologia ainda é indeterminada; acredita-se que existam fatores autoimunes e infecciosos envolvidos. No presente caso foi aventada possível relação com a vacina da influenza. Os sintomas da SPT incluem dor abrupta de um lado da cintura escapular, sendo característico o despertar noturno. É uma condição de difícil diagnóstico, podendo ser confundida inicialmente com espondilose cervical, capsulite adesiva, radiculopatia cervical e bursite. Na investigação diagnóstica, foram realizados exames laboratoriais e ressonâncias magnéticas e eletroneuromiografia que auxiliou na definição diagnóstica. O tratamento envolve a abordagem da dor neuropática e reabilitação visando a recuperacao da força e da função muscular. O objetivo dessa descrição é revisar o assunto através de um relato de caso típico mas que, no entanto, não foi inicialmente considerado, servindo de alerta para que diante de quadros de dor aguda em membros superiors seja ponderado o diagnóstico de Parsonage Turner. Dessa forma o assunto se torna mais habitual no ofício médico, facilitando o diagnóstico precoce e oferecendo o prognóstico ao paciente, evitando exames e medicações desnecessárias.


Parsonage-Turner Syndrome (SPT) is a rare disease that affects the musculature of the shoulder girdle, resulting in muscle hypotrophy and functional limitation. The etiology is still undertermined: It is believed that exist autoimune disorders and infections involved. In this case a possible relationship with the influenza vacinne was suggest. The symptoms of SPT include acute onset pain in one side of the shoulder girdle and frequently awakens pacients from sleep, fact that occurred in this report. This disease has difficult diagnostic and can be confused initially with cervical spondylosis, adhesive capsulitis, cervical radiculopathy and bursitis. In the diagnostic investigation, laboratory exams, magnetic resonances and electroneuromyography were performed, of the latter deserves mention for assisting in the definitive diagnosis and determining the extent of the lesion. There is still no protocol for specific treatment, but it should be focused on reducing neuropathic pain and recovering muscle strength and function. The purpose of this description is to review the subject through a typical case report, which, however, was not initially considered, serving as a warning so that in the face of acute pain in upper limbs, the diagnosis of Parsonage Turner should be considered. Thus, the subject becomes more usual in the medical craft making the clinical evaluation more careful so that the diagnosis is early and offers a better prognosis to the patient, avoiding unnecessary exams and medications.

6.
Rev Bras Ortop (Sao Paulo) ; 56(1): 69-73, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33627902

RESUMO

Objective To verify whether there is an association between the results of the severity in electroneuromyography and the positivity in ultrasound in the diagnosis of carpal tunnel syndrome. Methods Sixty-eight patients were included in the study, 61 women and 7 men, with a mean age of 54.4 years. The ultrasound results (positive or negative) were crossed with the results of electroneuromyography (mild, moderate or severe), and the existence of association was verified. Results One hundred and thirty-six hands with suspicion or symptoms of carpal tunnel syndrome were evaluated. Positive ultrasound diagnosis was observed in 72 hands and negative in 64; 123 hands presented positive electroneuromyography for carpal tunnel syndrome, and there were 13 negative results. The severe degree in electroneuromyography was prevalent. Conclusion There was a statistically significant association between electroneuromyography and ultrasonography ( p < 0.05), and ultrasound positivity was higher for more severe levels of carpal tunnel syndrome given by electroneuromyography.

7.
Rev. Bras. Ortop. (Online) ; 56(1): 69-73, Jan.-Feb. 2021. tab
Artigo em Inglês | LILACS | ID: biblio-1288659

RESUMO

Abstract Objective To verify whether there is an association between the results of the severity in electroneuromyography and the positivity in ultrasound in the diagnosis of carpal tunnel syndrome. Methods Sixty-eight patients were included in the study, 61 women and 7 men, with a mean age of 54.4 years. The ultrasound results (positive or negative) were crossed with the results of electroneuromyography (mild, moderate or severe), and the existence of association was verified. Results One hundred and thirty-six hands with suspicion or symptoms of carpal tunnel syndrome were evaluated. Positive ultrasound diagnosis was observed in 72 hands and negative in 64; 123 hands presented positive electroneuromyography for carpal tunnel syndrome, and there were 13 negative results. The severe degree in electroneuromyography was prevalent. Conclusion There was a statistically significant association between electroneuromyography and ultrasonography (p < 0.05), and ultrasound positivity was higher for more severe levels of carpal tunnel syndrome given by electroneuromyography.


Resumo Objetivo Verificar se existe associação entre os resultados da gravidade da eletroneuromiografia e a positividade da ultrassonografia no diagnóstico da síndrome do túnel do carpo. Métodos Sessenta e oito pacientes foram incluídos no estudo, sendo 61 mulheres e 7 homens, com média de idade de 54,4 anos. Os resultados da ultrassonografia (positivo ou negativo) foram cruzados com os resultados da eletroneuromiografia (leve, moderado ou grave) e verificada a existência de associação. Resultados Cento e trinta e seis mãos com suspeita ou sintomas de síndrome do túnel do carpo foram avaliadas. O diagnóstico ultrassonográfico positivo foi observado em 72 mãos e negativo em 64; 123 mãos apresentaram eletroneuromiografia positiva para síndrome do túnel do carpo e 13 apresentaram resultado negativo. O grau grave da eletroneuromiografia foi prevalente. Conclusão Houve associação estatisticamente significativa entre eletroneuromiografia e ultrassonografia (p < 0,05), sendo que a positividade da ultrassonografia foi maior para níveis mais graves de síndrome do túnel do carpo dados pela eletroneuromiografia.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Sinais e Sintomas , Síndrome do Túnel Carpal , Ultrassonografia , Resultados Negativos
8.
Cureus ; 12(11): e11464, 2020 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-33329961

RESUMO

Spinal muscular atrophy (SMA) is a rare, inherited autosomal recessive disease. Histopathological shreds of evidence related to the condition have suggested degenerative changes at the level of the spinal cord and brain stem. Deletions or mutations in the survival motor neuron 1 (SMN1) gene are the underlying cause of this disease. It is characterized by hypotonia, muscular atrophy, areflexia, fasciculations, and flaccid paralysis. It is further classified into five variants, depending upon the patient's age and clinical features. In this report, we present a rare case of SMA type 2 in a one-year-old female infant who presented with generalized hypotonia and axial body weakness. Besides clinical evaluation, her genetic analysis confirmed that she had a deletion of one of the SMN1 genes. Hence, the diagnosis of SMA type 2 was confirmed. Our study aims to emphasize that clinicians must consider this rare entity whenever a patient presents with the signs and symptoms mentioned above. As the most common cause of death in this disease is respiratory depression, an early diagnosis would prevent complications and help in the parents' genetic counseling.

9.
Photobiomodul Photomed Laser Surg ; 38(8): 477-480, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32716761

RESUMO

Background: Paralysis of the facial muscles produces functional and aesthetic disturbance that has a negative impact for the patient's quality of life. Objective: To evaluate the effects of a photobiomodulation (PBM) with low-level laser (LLL) on the treatment of a patient with 8 years of facial paralysis. Methods: PBM with two different wavelengths of LLL (660 and 808 nm), applied only on the affected side, three times a week for 8 consecutive weeks. Evaluations were performed before starting treatments, after the 12th session of treatment and after the 24th session, using the House-Brackmann scale and electroneuromyography. Results: The House-Brackmann and electroneuromyography tests showed improvements in the movement of the facial muscles when tested in the middle and at the end of the treatment with LLL. Conclusions: PBM with LLL at the wavelength of 660 and 808 nm with the parameters used in this case report was an effective and noninvasive treatment for facial paralysis in this long-standing, chronic case of 8 years.


Assuntos
Paralisia Facial/terapia , Terapia com Luz de Baixa Intensidade/métodos , Adulto , Doença Crônica , Eletromiografia , Músculos Faciais/efeitos da radiação , Nervo Facial/efeitos da radiação , Paralisia Facial/diagnóstico , Feminino , Humanos , Movimento , Fatores de Tempo
10.
Adv Rheumatol ; 59(1): 42, 2019 10 10.
Artigo em Inglês | MEDLINE | ID: mdl-31601261

RESUMO

BACKGROUND: This research is recommended by the Myopathy Committee of the Brazilian Society of Rheumatology for the investigation and diagnosis of systemic autoimmune myopathies. BODY: A systematic literature review was performed in the Embase, Medline (PubMed) and Cochrane databases, including studies published until October 2018. PRISMA was used for the review, and the articles were evaluated, based on the Oxford levels of evidence. Ten recommendations were developed addressing different aspects of systemic autoimmune myopathy investigation and diagnosis. CONCLUSIONS: The European League Against Rheumatism/ American College of Rheumatology (EULAR/ACR) classification stands out for the diagnosis of systemic autoimmune myopathies. Muscular biopsy is essential, aided by muscular magnetic resonance images and electroneuromyography in complementary research. Analysis of the factors related to prognosis with the evaluation of extramuscular manifestations, and comorbidities and intense investigation regarding differential diagnoses are mandatory.


Assuntos
Doenças Autoimunes/diagnóstico , Doenças Musculares/diagnóstico , Autoanticorpos/sangue , Doenças Autoimunes/tratamento farmacológico , Doenças Autoimunes/patologia , Biópsia , Brasil , Creatina Quinase/sangue , Dermatomiosite/diagnóstico , Eletromiografia/métodos , Humanos , Imageamento por Ressonância Magnética , Metanálise como Assunto , Debilidade Muscular/complicações , Músculo Esquelético/patologia , Doenças Musculares/tratamento farmacológico , Doenças Musculares/imunologia , Doenças Musculares/patologia , Miosite/diagnóstico , Miosite/imunologia , Miosite/patologia , Neoplasias/diagnóstico , Ensaios Clínicos Controlados Aleatórios como Assunto , Reumatologia , Sensibilidade e Especificidade , Sociedades Médicas
11.
Adv Rheumatol ; 59: 42, 2019. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1088587

RESUMO

Abstract Background: This research is recommended by the Myopathy Committee of the Brazilian Society of Rheumatology for the investigation and diagnosis of systemic autoimmune myopathies. Body: A systematic literature review was performed in the Embase, Medline (PubMed) and Cochrane databases, including studies published until October 2018. PRISMA was used for the review, and the articles were evaluated, based on the Oxford levels of evidence. Ten recommendations were developed addressing different aspects of systemic autoimmune myopathy investigation and diagnosis. Conclusions: The European League Against Rheumatism/ American College of Rheumatology (EULAR/ACR) classification stands out for the diagnosis of systemic autoimmune myopathies. Muscular biopsy is essential, aided by muscular magnetic resonance images and electroneuromyography in complementary research. Analysis of the factors related to prognosis with the evaluation of extramuscular manifestations, and comorbidities and intense investigation regarding differential diagnoses are mandatory.

12.
Arq. bras. med. vet. zootec. (Online) ; 70(6): 1754-1758, nov.-dez. 2018. graf
Artigo em Português | LILACS, VETINDEX | ID: biblio-970331

RESUMO

Diversos fármacos são utilizados no tratamento da epilepsia e, assim como outros medicamentos, podem induzir a ocorrência de efeitos adversos, alguns tão graves que geram a necessidade de descontinuidade e substituição da terapia. A carbamazepina pode levar a alterações nos sistemas cardiovascular, respiratório e neurológico, sendo descritos na literatura casos de indução de miastenia gravis como distúrbio neuromuscular. Este estudo relata o caso de um cão que desenvolveu polirradiculoneuropatia desmielinizante, tendo como provável desencadeante a terapia com carbamazepina. O paciente apresentou tetraplegia, ausência de reflexos espinhais nos quatro membros, fraqueza cervical, diminuição do reflexo palpebral bilateral e esforço respiratório. A eletroneuromiografia demonstrou sinais de desmielinização. Este, portanto, é o primeiro relato de associação entre carbamazepina e polirradiculoneuropatia desmielinizante em cão.(AU)


Different drugs are used in the treatment of epilepsy and, like other drugs, may induce the occurrence of adverse effects, some of them so severe that the drug must be discontinued and replaced. Carbamazepine may lead to changes in the cardiovascular, respiratory, and neurological systems, and cases of induction of myasthenia gravis as a neuromuscular disorder have been described in the literature. This paper reports the case of a dog that developed demyelinating polyradiculoneuropathy, probably triggered by carbamazepine. The patient presented tetraplegia, absence of spinal reflexes in the four limbs, cervical weakness, decreased bilateral eyelid reflex and respiratory effort. Electroneuromyography showed signs of demyelination. This, therefore, is the first report of association between carbamazepine and demyelinating polyradiculoneuropathy in dogs.(AU)


Assuntos
Animais , Cães , Polirradiculoneuropatia/veterinária , Carbamazepina/administração & dosagem , Cães/anormalidades
13.
Arq. bras. med. vet. zootec. (Online) ; 70(6): 1754-1758, nov.-dez. 2018. graf
Artigo em Português | VETINDEX | ID: vti-21307

RESUMO

Diversos fármacos são utilizados no tratamento da epilepsia e, assim como outros medicamentos, podem induzir a ocorrência de efeitos adversos, alguns tão graves que geram a necessidade de descontinuidade e substituição da terapia. A carbamazepina pode levar a alterações nos sistemas cardiovascular, respiratório e neurológico, sendo descritos na literatura casos de indução de miastenia gravis como distúrbio neuromuscular. Este estudo relata o caso de um cão que desenvolveu polirradiculoneuropatia desmielinizante, tendo como provável desencadeante a terapia com carbamazepina. O paciente apresentou tetraplegia, ausência de reflexos espinhais nos quatro membros, fraqueza cervical, diminuição do reflexo palpebral bilateral e esforço respiratório. A eletroneuromiografia demonstrou sinais de desmielinização. Este, portanto, é o primeiro relato de associação entre carbamazepina e polirradiculoneuropatia desmielinizante em cão.(AU)


Different drugs are used in the treatment of epilepsy and, like other drugs, may induce the occurrence of adverse effects, some of them so severe that the drug must be discontinued and replaced. Carbamazepine may lead to changes in the cardiovascular, respiratory, and neurological systems, and cases of induction of myasthenia gravis as a neuromuscular disorder have been described in the literature. This paper reports the case of a dog that developed demyelinating polyradiculoneuropathy, probably triggered by carbamazepine. The patient presented tetraplegia, absence of spinal reflexes in the four limbs, cervical weakness, decreased bilateral eyelid reflex and respiratory effort. Electroneuromyography showed signs of demyelination. This, therefore, is the first report of association between carbamazepine and demyelinating polyradiculoneuropathy in dogs.(AU)


Assuntos
Animais , Cães , Polirradiculoneuropatia/veterinária , Carbamazepina/administração & dosagem , Cães/anormalidades
14.
Rev. dor ; 17(supl.1): 23-26, 2016. tab, graf
Artigo em Inglês | LILACS | ID: lil-795158

RESUMO

ABSTRACT BACKGROUND AND OBJECTIVES: Neuropathic pain is defined as pain induced by injury or disease involving the somatosensory system. Dysfunctions in anatomic regions responsible for the processing of pain may involve peripheral and central nervous system components. A careful history and clinical evaluation with special attention to neurologic propaedeutics are critical for the syndromic, anatomic and etiologic diagnosis of neuropathic pain. However, diagnosis is not always simple and often depends on additional tests. This chapter aimed at reviewing most commonly used additional tests in the clinical practice to help diagnosing neuropathic pain. CONTENTS: Electroneuromyography is primarily indicated for topographic, etiologic and prognostic diagnosis of peripheral nervous system diseases and for the differential diagnosis between neurogenic, myopathic and neuromuscular junction diseases. It gives real time information on what is going on in the nerve and the muscle, being fundamentally important for differential neuromuscular disease diagnosis. Some imaging methods, such as computerized tomography and magnetic resonance, for their spatial resolution, give details of anatomic structures. Other methods, such as positron emission tomography scan and functional magnetic resonance, in addition to anatomic details, also provide data on metabolic and functional measurements. In addition, imaging techniques such as spectroscopy and diffusion tensor magnetic resonance, allow the study of brain biochemical changes and conectivities with different temporal and spatial resolutions. Other additional tests, such as sensory quantification test and microneurography are seldom used in the clinical practice. CONCLUSION: Additional tests, together with careful history and neurological evaluation focused on neurologic propaedeutics, may provide important data for the diagnosis of neuropathic pain and are often used in the clinical practice.


RESUMO JUSTIFICATIVA E OBJETIVOS: Dor neuropática é definida como a dor causada por lesão ou doença envolvendo o sistema somatossensitivo. Disfunções em regiões anatômicas responsáveis pelo processamento da dor podem envolver componentes do sistema nervoso periférico e central. Uma anamnese cuidadosa e um exame clínico com particular atenção na propedêutica neurológica são fundamentais para o diagnóstico sindrômico, anatômico e etiológico das dores neuropáticas. Entretanto, o diagnóstico nem sempre é simples e frequentemente depende do auxílio de exames complementares. O objetivo deste capítulo foi rever os exames complementares mais usados na prática clínica para o auxílio diagnóstico na dor neuropática. CONTEÚDO: O exame eletroneuromiográfico tem sua principal indicação no diagnóstico topográfico, etiológico e prognóstico das afecções do sistema nervoso periférico e no diagnóstico diferencial entre afecções neurogênicas, miopáticas e da junção neuromuscular. Ele pode fornecer informações em tempo real do que está ocorrendo no nervo e no músculo, sendo de fundamental importância no diagnóstico diferencial das afecções neuromusculares. Existem várias modalidades não invasivas de estudo por imagem que podem auxiliar no diagnóstico de quadros de dores neuropáticas. Alguns métodos por imagem como a tomografia computadorizada, ressonância magnética, pela sua resolução espacial, fornecem detalhamento sobre as estruturas anatômicas. Outros métodos como a tomografia computadorizada por emissão de pósitrons, ressonância magnética funcional fornecem além do detalhamento anatômico, dados sobre mensurações metabólicas e funcionais. Além disso, técnicas de imagem como espectroscopia e tensor de difusão por ressonância magnética, permitem estudar alterações bioquímicas e conectividades cerebrais com diferentes resoluções temporais e espaciais. Outros exames complementares como teste de quantificação sensitiva e microneurografia são pouco utilizados na prática clínica. CONCLUSÃO: Exames complementares, em conjunto com uma anamnese cuidadosa e exame neurológico focado na propedêutica neurológica, podem fornecer dados importantes para o diagnóstico de dor neuropática e são frequentemente utilizados na prática clínica.

15.
Rev. bras. neurol ; 46(3)jul.-set. 2010. ilus
Artigo em Português | LILACS | ID: lil-564325

RESUMO

As amiotrofias espinhais progressivas (AEP) são um grupo de desordens geneticamente determinadas marcadas pela depleção dos neurônios da ponta anterior da medula espinhal e, frequentemente, núcleos de nervos cranianos (bulbares). A forma mais comum de AEP usualmente compromete os músculos proximais dos membros. Entretanto, existe uma forma incomum, usualmente esporádica, que envolve somente a região distal braquial. A proposta do presente relato é apresentar os achados clínicos e eletrofisiológicos de um paciente com AEP crônica e com comprometimento dos músculos do terço distal dos membros superiores. A eletroneumiografia revelou anormalidades neurogênicas e potenciais de desnervação com velocidade de condução sensitiva e motora normais. Descrevemos algumas teorias acerca da fisiopatologia. O reconhecimento dessa forma infrequente é muito importante para uma ótima abordagem terapêutica nesses pacientes.


The spinal muscular atrophies (SMA) are a group of genetically determined disorders in which the primary defect is a loss of the anterior horn neurons of the spinal cord and, commonly, of nuclei of cranial nerves (medulla). A more common chronic form of SMA usually affects proximal limb muscles. However, there is an uncommon form, frequently sporadic, involving only the distal part of upper limbs. The purpose of the present report is to describe the clinical and electrophysiological features of a patient with chronic SMA affecting the muscles of the distal third of the upper limbs. Electroneuromyography revealed neurogenic anomalies and denervation potentials with normal motor and sensory nerve conduction velocities. We describe some theories concerning its pathophysiology. The recognition of this infrequent form is very important for an optimized therapeutical approach of this kind of patients.


Assuntos
Humanos , Masculino , Adulto , Antebraço/fisiopatologia , Atrofia Muscular Espinal/complicações , Atrofia Muscular Espinal/diagnóstico , Mãos/fisiopatologia , Eletromiografia
16.
Artigo em Português | LILACS-Express | VETINDEX | ID: biblio-1488880

RESUMO

Although history, clinical findings, and neurological exams can be used to determine an interim diagnosis of neurological diseases, final confirmation usually requires additional diagnostic tests. This article describes electrodiagnostic tests such as electromyography and nerve stimulation studies, which have become an invaluable tool to evaluate muscles, neuromuscular junctions, peripheral nerves and the spinal cord.


Apesar de a história clínica associada aos achados do exame físico e neurológico permitirem o diagnóstico de uma doença neurológica, muitas vezes a confirmação do quadro necessita de exames complementares específicos. Este artigo descreve os testes eletrodiagnósticos que tem sido utilizados para avaliar a musculatura esquelética, as junções neuromusculares, os nervos periféricos e a medula espinhal, tais como a eletromiografia e os estudos de estimulação nervosa.

17.
Artigo em Português | VETINDEX | ID: vti-455138

RESUMO

Although history, clinical findings, and neurological exams can be used to determine an interim diagnosis of neurological diseases, final confirmation usually requires additional diagnostic tests. This article describes electrodiagnostic tests such as electromyography and nerve stimulation studies, which have become an invaluable tool to evaluate muscles, neuromuscular junctions, peripheral nerves and the spinal cord.


Apesar de a história clínica associada aos achados do exame físico e neurológico permitirem o diagnóstico de uma doença neurológica, muitas vezes a confirmação do quadro necessita de exames complementares específicos. Este artigo descreve os testes eletrodiagnósticos que tem sido utilizados para avaliar a musculatura esquelética, as junções neuromusculares, os nervos periféricos e a medula espinhal, tais como a eletromiografia e os estudos de estimulação nervosa.

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