RESUMO

Feline sporotrichosis is a zoonotic mycosis caused by fungi belonging to the Sporothrix schenckii complex. In the state of Ceará, there are no reports of isolation of this fungus in cats. This study presents the first report of feline sporotrichosis caused by the species Sporothrix brasiliensis in the state of Ceará - Brazil. The diagnosis was made through cytopathological examination, mycological culture and PCR. The findings were compatible with feline sporotrichosis caused by Sporothrix brasiliensis.

RESUMO

O carcinoma de células escamosas (CCE) é uma neoplasia maligna resultante da diferenciação de ceratinócitos, que acomete principalmente animais de pelagem clara e pouco pigmentados, decorrente da exposição à radiação ultravioleta. Apresentam evolução lenta e baixo caráter metastático, porém, em alguns mais avançados pode ocorrer acometimento metastático de órgãos adjacentes. Os tratamentos utilizados no CCE incluem cirurgia, radioterapia, quimioterapia, crioterapia e eletroquimioterapia (EQT). A eletroquimioterapia se mostra bastante eficaz no tratamento desse tumor, dentre outros e comumente não apresenta efeito colateral. O presente trabalho tem como objetivo relatar o caso de um felino atendido na Clínica Veterinária Bichos S.A. no município de Foz do Iguaçu, diagnosticado com Carcinoma de Células Escamosas e portador do vírus da imunodefiência felina. O tratamento adotado para a neoplasia foi a eletroquimioterapia, resultando em remissão parcial das lesões, após vinte dias da EQT. Com objetivo de investigar possível acometimento ósseo, foi realizada radiografia de face, onde a mesma apresentou área de lise óssea em arco zigomático e maxila esquerda, indicativo de infiltração neoplásica. A radiografia torácica apontou presença de área nodular sobrepondo lobo pulmonar caudal direito, indicativo de processo metastático. Em virtude do prognóstico reservado, os tutores optaram pela eutanásia do mesmo.(AU)

Squamous cell carcinoma (SCC) is a malignant neoplasm resulting from the differentiation of keratinocytes, which mainly affects light-colored and non-pigmented animals due to exposure to ultraviolet radiation. Although they present slow evolution and low metastatic character, in some more advanced cases, metastatic involvement of adjacent organs may occur. The treatments used in SCC include surgery, radiotherapy, chemotherapy, cryotherapy and electrochemotherapy (ECT). Electrochemotherapy is quite effective in the treatment of this type of tumor, among others, and it usually has no side effect. This work aims at reporting the case of a feline treated at the Veterinary Clinic Bichos S.A. in the city of Foz do Iguaçu diagnosed with Squamous Cell Carcinoma and carrying the feline immunodefense virus (FIV). Electrochemotherapy was the treatment of choice for the neoplasia, resulting in partial remission of the lesions after twenty days of treatment. In order to investigate possible bone involvement, an X-ray of the face was performed, where it presented area of bone lysis in the zygomatic arch and left maxilla, signs of neoplastic infiltration. The chest X-ray showed a nodular area overlapping the right caudal pulmonary lobe, an indication of metastatic process. Due to the reserved prognosis, the tutors chose euthanasia of the subject.(AU)

El carcinoma de células escamosas (CEC) es una neoplasia maligna resultante de la diferenciación de queratinocitos, que afecta principalmente a animales de pelaje claro y de poca pigmentación, resultado de la exposición a la radiación ultravioleta. Tienen una evolución lenta y un carácter metastásico bajo, sin embargo, en algunos más avanzados puede producirse afectación metastásica de órganos adyacentes. Los tratamientos utilizados en el CEC incluyen cirugía, radioterapia, quimioterapia, crioterapia y electroquimioterapia (EQT). La electroquimioterapia es muy eficaz en el tratamiento de ese tumor, entre otros y no suele tener efectos secundarios. Este trabajo tiene como objetivo reportar el caso de un felino atendido en la Clínica Veterinária Bichos S.A. de la ciudad de Foz do Iguaçu, diagnosticado con Carcinoma de Células Escamosas y con el virus de la inmunodeficiencia felina. El tratamiento adoptado para la neoplasia fue la electroquimioterapia, resultando en remisión parcial de las lesiones luego de veinte días de EQT. Con el fin de investigar la posible afectación ósea se realizó una radiografía de rostro, donde se presentó un área de lisis ósea en arco cigomático y maxilar izquierdo, indicativo de infiltración neoplásica. La radiografía de tórax mostró la presencia de un área nodular superpuesta al lóbulo pulmonar caudal derecho, lo que indicaba un proceso metastásico. Debido al pronóstico reservado, los tutores optaron por la eutanasia.(AU)

Assuntos

RESUMO

O carcinoma de células escamosas (CCE) é uma neoplasia maligna resultante da diferenciação de ceratinócitos, que acomete principalmente animais de pelagem clara e pouco pigmentados, decorrente da exposição à radiação ultravioleta. Apresentam evolução lenta e baixo caráter metastático, porém, em alguns mais avançados pode ocorrer acometimento metastático de órgãos adjacentes. Os tratamentos utilizados no CCE incluem cirurgia, radioterapia, quimioterapia, crioterapia e eletroquimioterapia (EQT). A eletroquimioterapia se mostra bastante eficaz no tratamento desse tumor, dentre outros e comumente não apresenta efeito colateral. O presente trabalho tem como objetivo relatar o caso de um felino atendido na Clínica Veterinária Bichos S.A. no município de Foz do Iguaçu, diagnosticado com Carcinoma de Células Escamosas e portador do vírus da imunodefiência felina. O tratamento adotado para a neoplasia foi a eletroquimioterapia, resultando em remissão parcial das lesões, após vinte dias da EQT. Com objetivo de investigar possível acometimento ósseo, foi realizada radiografia de face, onde a mesma apresentou área de lise óssea em arco zigomático e maxila esquerda, indicativo de infiltração neoplásica. A radiografia torácica apontou presença de área nodular sobrepondo lobo pulmonar caudal direito, indicativo de processo metastático. Em virtude do prognóstico reservado, os tutores optaram pela eutanásia do mesmo.(AU)

Squamous cell carcinoma (SCC) is a malignant neoplasm resulting from the differentiation of keratinocytes, which mainly affects light-colored and non-pigmented animals due to exposure to ultraviolet radiation. Although they present slow evolution and low metastatic character, in some more advanced cases, metastatic involvement of adjacent organs may occur. The treatments used in SCC include surgery, radiotherapy, chemotherapy, cryotherapy and electrochemotherapy (ECT). Electrochemotherapy is quite effective in the treatment of this type of tumor, among others, and it usually has no side effect. This work aims at reporting the case of a feline treated at the Veterinary Clinic Bichos S.A. in the city of Foz do Iguaçu diagnosed with Squamous Cell Carcinoma and carrying the feline immunodefense virus (FIV). Electrochemotherapy was the treatment of choice for the neoplasia, resulting in partial remission of the lesions after twenty days of treatment. In order to investigate possible bone involvement, an X-ray of the face was performed, where it presented area of bone lysis in the zygomatic arch and left maxilla, signs of neoplastic infiltration. The chest X-ray showed a nodular area overlapping the right caudal pulmonary lobe, an indication of metastatic process. Due to the reserved prognosis, the tutors chose euthanasia of the subject.(AU)

El carcinoma de células escamosas (CEC) es una neoplasia maligna resultante de la diferenciación de queratinocitos, que afecta principalmente a animales de pelaje claro y de poca pigmentación, resultado de la exposición a la radiación ultravioleta. Tienen una evolución lenta y un carácter metastásico bajo, sin embargo, en algunos más avanzados puede producirse afectación metastásica de órganos adyacentes. Los tratamientos utilizados en el CEC incluyen cirugía, radioterapia, quimioterapia, crioterapia y electroquimioterapia (EQT). La electroquimioterapia es muy eficaz en el tratamiento de ese tumor, entre otros y no suele tener efectos secundarios. Este trabajo tiene como objetivo reportar el caso de un felino atendido en la Clínica Veterinária Bichos S.A. de la ciudad de Foz do Iguaçu, diagnosticado con Carcinoma de Células Escamosas y con el virus de la inmunodeficiencia felina. El tratamiento adoptado para la neoplasia fue la electroquimioterapia, resultando en remisión parcial de las lesiones luego de veinte días de EQT. Con el fin de investigar la posible afectación ósea se realizó una radiografía de rostro, donde se presentó un área de lisis ósea en arco cigomático y maxilar izquierdo, indicativo de infiltración neoplásica. La radiografía de tórax mostró la presencia de un área nodular superpuesta al lóbulo pulmonar caudal derecho, lo que indicaba un proceso metastásico. Debido al pronóstico reservado, los tutores optaron por la eutanasia.(AU)

Assuntos

RESUMO

The aim of this study were to detect antibodies anti-Leishmania spp. and anti-Trypanosoma cruzi in two different populations of domestic cats (Felis catus domesticus) from North Paraná referred for surgical castration and to determine which characteristics of the animals studied may be associated with seropositivity. Serum samples from 679 cats were analyzed using enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence antibody test (IFAT) in series. Associations between age, sex, race, year of care and animal group were verified using the simple logistic regression. Percentage of 8.5% (58/679) of cats were positive for Leishmania spp. and 7.6% (51/673) for T. cruzi by the tests ELISA and IFAT. Animals collected by non-governmental animal protection organizations presented more seropositivity for Leishmania spp. (p 0.0001). Results shown that Leishmania spp. and T. cruzi are present in domestic cats in the northern part of the state of Paraná, as well as, owners of non-governmental animal protection organizations may be more exposed to leishmaniasis when compared to other animal owners evaluated in the present study.(AU)

O objetivo desse estudo foi detectar a presença de anticorpos IgG anti-Leishmania spp. e anti-Trypanosoma cruzi em duas populações de gatos domésticos (Felis catus domesticus) do Norte do Paraná encaminhados para castração cirúrgica e determinar quais as características dos animais estudados que podem estar associadas à soropositividade. Amostras de soro de 679 gatos foram analisadas utilizando-se os testes imunoenzimático (ELISA) e a reação de imunofluorescência indireta (RIFI), em série. Associações entre idade, sexo, raça, ano de atendimento e grupo animal foram verificadas usando regressão logística simples. Um percentual de 8,5% (58/679) dos gatos apresentou positividade para Leishmania spp. e 7,6% (51/673) para T. cruzi pelos testes ELISA e RIFI. Gatos mantidos em organizações não governamentais de proteção animal apresentaram maior sororeatividade para Leishmania spp. (p 0.0001). As sorologias reativas para Leishmania spp. e Trypanosoma cruzi mostram que esses agentes estão presentes em gatos domésticos na parte norte do estado do Paraná, bem como, os proprietários de organizações não governamentais de proteção animal podem estar mais expostos à leishmaniose quando comparados com outros proprietários de animais avaliados no presente estudo.(AU)

Assuntos

RESUMO

Abstract The aim of this study were to detect antibodies anti-Leishmania spp. and anti-Trypanosoma cruzi in two different populations of domestic cats (Felis catus domesticus) from North Paraná referred for surgical castration and to determine which characteristics of the animals studied may be associated with seropositivity. Serum samples from 679 cats were analyzed using enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence antibody test (IFAT) in series. Associations between age, sex, race, year of care and animal group were verified using the simple logistic regression. Percentage of 8.5% (58/679) of cats were positive for Leishmania spp. and 7.6% (51/673) for T. cruzi by the tests ELISA and IFAT. Animals collected by non-governmental animal protection organizations presented more seropositivity for Leishmania spp. (p<0.0001). Results shown that Leishmania spp. and T. cruzi are present in domestic cats in the northern part of the state of Paraná, as well as, owners of non-governmental animal protection organizations may be more exposed to leishmaniasis when compared to other animal owners evaluated in the present study.

Resumo O objetivo desse estudo foi detectar a presença de anticorpos IgG anti-Leishmania spp. e anti-Trypanosoma cruzi em duas populações de gatos domésticos (Felis catus domesticus) do Norte do Paraná encaminhados para castração cirúrgica e determinar quais as características dos animais estudados que podem estar associadas à soropositividade. Amostras de soro de 679 gatos foram analisadas utilizando-se os testes imunoenzimático (ELISA) e a reação de imunofluorescência indireta (RIFI), em série. Associações entre idade, sexo, raça, ano de atendimento e grupo animal ​​foram verificadas usando regressão logística simples. Um percentual de 8,5% (58/679) dos gatos apresentou positividade para Leishmania spp. e 7,6% (51/673) para T. cruzi pelos testes ELISA e RIFI. Gatos mantidos em organizações não governamentais de proteção animal apresentaram maior sororeatividade para Leishmania spp. (p<0.0001). As sorologias reativas para Leishmania spp. e Trypanosoma cruzi mostram que esses agentes estão presentes em gatos domésticos na parte norte do estado do Paraná, bem como, os proprietários de organizações não governamentais de proteção animal podem estar mais expostos à leishmaniose quando comparados com outros proprietários de animais avaliados no presente estudo.

Assuntos

RESUMO

A castração é um procedimento cirúrgico que visa a remoção dos órgãos reprodutivo de machos e fêmeas de um animal. É uma das principais formas de controle populacional de uma espécie. Além do controle reprodutivo, a castração possuir efeitos no comportamento e na biologia do animal castrado. Um dos animais que mais vivenciam este procedimento é o gato doméstico, seja para controlar o número de animais errantes, reduzir encontros agonísticos, diminuir a área de uso, proporcionar a guarda responsável e reduzir a ocorrência de comportamentos entendidos como indesejáveis que levariam a atos como abandono e maus-tratos. De um modo geral entende-se que a prática proporciona condições para elevação do bem-estar do gato doméstico. Todavia, questionamentos éticos e clínicos sobre a sua execução e os efeitos biológicos e comportamentais são importantes. O objetivo do presente estudo portanto é discutir se a castração é defensável sob o ponto de vista do bem-estar do gato doméstico levando-se em consideração questões biológicas, comportamentais, éticas e ecológicas.(AU) 

Castration is a surgical procedure aimed to remove reproductive organs of males and females animals. It is one of the main forms of population control. In addition to reproductive control, castration haseffects on the behavior and biology. One of the animals that most experience this procedure is the domestic cat, to control the number of abandoned animals, diminish agonistic encounters, to reduce the area of use, to provide responsible care and to reduce the occurrence of undesirable behaviors that would lead to acts such as neglect and mistreatment. In general,it is understood that the practice provides conditions for raising the welfare of the domestic cat. However, ethical andclinical questions and the biological and behavioral effects are important. The objective of the present study is therefore to discuss whether castration is defensible from the point of view of domestic cat welfare taking into account biological, behavioral, ethical and ecological issues.(AU)

Assuntos

RESUMO

A castração é um procedimento cirúrgico que visa a remoção dos órgãos reprodutivo de machos e fêmeas de um animal. É uma das principais formas de controle populacional de uma espécie. Além do controle reprodutivo, a castração possuir efeitos no comportamento e na biologia do animal castrado. Um dos animais que mais vivenciam este procedimento é o gato doméstico, seja para controlar o número de animais errantes, reduzir encontros agonísticos, diminuir a área de uso, proporcionar a guarda responsável e reduzir a ocorrência de comportamentos entendidos como indesejáveis que levariam a atos como abandono e maus-tratos. De um modo geral entende-se que a prática proporciona condições para elevação do bem-estar do gato doméstico. Todavia, questionamentos éticos e clínicos sobre a sua execução e os efeitos biológicos e comportamentais são importantes. O objetivo do presente estudo portanto é discutir se a castração é defensável sob o ponto de vista do bem-estar do gato doméstico levando-se em consideração questões biológicas, comportamentais, éticas e ecológicas.

Castration is a surgical procedure aimed to remove reproductive organs of males and females animals. It is one of the main forms of population control. In addition to reproductive control, castration haseffects on the behavior and biology. One of the animals that most experience this procedure is the domestic cat, to control the number of abandoned animals, diminish agonistic encounters, to reduce the area of use, to provide responsible care and to reduce the occurrence of undesirable behaviors that would lead to acts such as neglect and mistreatment. In general,it is understood that the practice provides conditions for raising the welfare of the domestic cat. However, ethical andclinical questions and the biological and behavioral effects are important. The objective of the present study is therefore to discuss whether castration is defensible from the point of view of domestic cat welfare taking into account biological, behavioral, ethical and ecological issues.

Assuntos

RESUMO

Abstract Toxoplasmosis is an infectious, zoonotic and parasitic disease, caused by Toxoplasma gondii. In this manucript, two cases of infection with T. gondii in captive animals from a zoological park in the central region of Chile are described. One case was a red kangaroo (Macropus rufus), which is highly susceptible to the infection, and the other was a Patagonian mara (Dolichotis patagonum), a rodent in which there is no previous report of the infection. Both animals had myocarditis, with the presence of intralesional tachizoites and cysts suggestive of infection with T. gondii. This infection was confirmed by immunohistochemistry in both animals. The origin of the infection is unknown, but it is likely that free ranging domestic felines were associated with the dissemination of the parasites. This highlights the importance of controlling the domestic animal populations in zoological parks. To the best of our knowledge, this is the first time that T. gondii infection is described in a Patagonian mara, adding a new host for this infectious agent.

Resumo Toxoplasmose é uma doença parasitária infecciosa e zoonótica causada por Toxoplasma gondii. São descritos dois animais com toxoplasmose, mantidos em cativeiro, em um zoológico na região central do Chile. Um destes foi um canguru vermelho (Macropus rufus), o qual é altamente suscetível à infecção; o outro foi uma mara (Dolichotis patagonum), um roedor sem relato prévio de infecção por T. gondii. Ambos os animais tinham miocardite associada a organismos protozoários intralesionais, sugestivos de infecção por Toxoplasma gondii. Esta infecção foi confirmada pela imuno-histoquímica, nos dois animais. A origem da infecção é desconhecida, mas é provável que felinos domésticos errantes estejam associados com a disseminação do protozoário. Isso destaca a importância do controle populacional de animais domésticos em zoológicos. Até onde se sabe, esta é a primeira vez que a infecção por T. gondii é descrita em uma mara, adicionando um novo hospedeiro para este agente infeccioso.

Assuntos

RESUMO

Abstract Toxoplasmosis is an infectious, zoonotic and parasitic disease, caused by Toxoplasma gondii. In this manucript, two cases of infection with T. gondii in captive animals from a zoological park in the central region of Chile are described. One case was a red kangaroo (Macropus rufus), which is highly susceptible to the infection, and the other was a Patagonian mara (Dolichotis patagonum), a rodent in which there is no previous report of the infection. Both animals had myocarditis, with the presence of intralesional tachizoites and cysts suggestive of infection with T. gondii. This infection was confirmed by immunohistochemistry in both animals. The origin of the infection is unknown, but it is likely that free ranging domestic felines were associated with the dissemination of the parasites. This highlights the importance of controlling the domestic animal populations in zoological parks. To the best of our knowledge, this is the first time that T. gondii infection is described in a Patagonian mara, adding a new host for this infectious agent.(AU)

Resumo Toxoplasmose é uma doença parasitária infecciosa e zoonótica causada por Toxoplasma gondii. São descritos dois animais com toxoplasmose, mantidos em cativeiro, em um zoológico na região central do Chile. Um destes foi um canguru vermelho (Macropus rufus), o qual é altamente suscetível à infecção; o outro foi uma mara (Dolichotis patagonum), um roedor sem relato prévio de infecção por T. gondii. Ambos os animais tinham miocardite associada a organismos protozoários intralesionais, sugestivos de infecção por Toxoplasma gondii. Esta infecção foi confirmada pela imuno-histoquímica, nos dois animais. A origem da infecção é desconhecida, mas é provável que felinos domésticos errantes estejam associados com a disseminação do protozoário. Isso destaca a importância do controle populacional de animais domésticos em zoológicos. Até onde se sabe, esta é a primeira vez que a infecção por T. gondii é descrita em uma mara, adicionando um novo hospedeiro para este agente infeccioso.(AU)

Assuntos

RESUMO

The aim of this study was to characterize the renal morphology and anatomical variations of the renal pedicle in domestic shorthaired cats. Dissections were performed in 40 adult cats, obtained from the necropsy unit without macroscopic renal pathology. Kidney dimensions (length, width, and thickness) and the length and origin of the renal arteries and main branches were measured. The length, width and thickness of the right kidney (cm) were 3.83±0.46, 2.42±0.22, and 2.22±0.33 in males, and 3.61±0.53, 2.28±0.38, and 2.13±0.40 in females, respectively. In the left kidney, these measures were 3.82±0.32, 2.48±0.31, and 2.37±0.32 in males, and 3.48±0.47, 2.39±0.26, and 2.15±0.34 in females, respectively. The left kidneys of males were significantly bigger than those of females. There was a positive linear correlation between the rostrum-sacral length and ellipsoid volume of the left kidney only in males. Most of the kidneys were situated ventrally between the third to fifth lumbar vertebras. The right renal artery was situated ventrally to third lumbar vertebra and the left artery to the fourth. The results of the present study contribute to the field of comparative and applied anatomy.(AU)

O objetivo deste estudo foi caracterizar a morfologia renal e as variações anatômicas do pedículo renal em gatos de pelo curto brasileiro. As dissecções foram realizadas em 40 gatos adultos, obtidos de necropsias sem evidência de patologia renal macroscópica. Medidas renais (comprimento, largura e espessura), comprimento e origem das artérias renais e ramos principais foram obtidos. O comprimento, a largura e a espessura do rim direito (cm) foram 3,83 ± 0,46, 2,42 ± 0,22 e 2,22 ± 0,33 em machos e 3,61 ± 0,53, 2,28 ± 0,38 e 2,13 ± 0,40 em fêmeas, respectivamente. No rim esquerdo, essas medidas foram 3,82 ± 0,32, 2,48 ± 0,31 e 2,37 ± 0,32 em machos e 3,48 ± 0,47, 2,39 ± 0,26 e 2,15 ± 0,34 em fêmeas, respectivamente. O rim esquerdo dos machos foi maior do que o das fêmeas. Houve correlação linear positiva entre o comprimento rostrossacral e o volume elipsoide do rim esquerdo apenas em machos. A maioria dos rins estão situados ventralmente entre a terceira e quinta vértebras lombares. A artéria renal direita está situada ventralmente na terceira vértebra lombar, e a artéria renal esquerda na quarta. Os resultados do presente estudo contribuem para a anatomia comparada e aplicada.(AU)

Assuntos

RESUMO

The aim of this study was to characterize the renal morphology and anatomical variations of the renal pedicle in domestic shorthaired cats. Dissections were performed in 40 adult cats, obtained from the necropsy unit without macroscopic renal pathology. Kidney dimensions (length, width, and thickness) and the length and origin of the renal arteries and main branches were measured. The length, width and thickness of the right kidney (cm) were 3.83±0.46, 2.42±0.22, and 2.22±0.33 in males, and 3.61±0.53, 2.28±0.38, and 2.13±0.40 in females, respectively. In the left kidney, these measures were 3.82±0.32, 2.48±0.31, and 2.37±0.32 in males, and 3.48±0.47, 2.39±0.26, and 2.15±0.34 in females, respectively. The left kidneys of males were significantly bigger than those of females. There was a positive linear correlation between the rostrum-sacral length and ellipsoid volume of the left kidney only in males. Most of the kidneys were situated ventrally between the third to fifth lumbar vertebras. The right renal artery was situated ventrally to third lumbar vertebra and the left artery to the fourth. The results of the present study contribute to the field of comparative and applied anatomy.(AU)

O objetivo deste estudo foi caracterizar a morfologia renal e as variações anatômicas do pedículo renal em gatos de pelo curto brasileiro. As dissecções foram realizadas em 40 gatos adultos, obtidos de necropsias sem evidência de patologia renal macroscópica. Medidas renais (comprimento, largura e espessura), comprimento e origem das artérias renais e ramos principais foram obtidos. O comprimento, a largura e a espessura do rim direito (cm) foram 3,83 ± 0,46, 2,42 ± 0,22 e 2,22 ± 0,33 em machos e 3,61 ± 0,53, 2,28 ± 0,38 e 2,13 ± 0,40 em fêmeas, respectivamente. No rim esquerdo, essas medidas foram 3,82 ± 0,32, 2,48 ± 0,31 e 2,37 ± 0,32 em machos e 3,48 ± 0,47, 2,39 ± 0,26 e 2,15 ± 0,34 em fêmeas, respectivamente. O rim esquerdo dos machos foi maior do que o das fêmeas. Houve correlação linear positiva entre o comprimento rostrossacral e o volume elipsoide do rim esquerdo apenas em machos. A maioria dos rins estão situados ventralmente entre a terceira e quinta vértebras lombares. A artéria renal direita está situada ventralmente na terceira vértebra lombar, e a artéria renal esquerda na quarta. Os resultados do presente estudo contribuem para a anatomia comparada e aplicada.(AU)

Assuntos

RESUMO

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemic disease (FCV-VSD), which has not yet been reported in Brazil. The aim of the present study was to investigate the presence of antibodies against FCV and FeHV-1 in the population of domestic felines from some counties of the Rio Grande do Sul State (RS), using a virus neutralizing (VN) assay. Materials, Methods & Results: A total of 630 feline serum samples collected between the years 2007 and 2011 were analyzed to detect antibodies against FCV and FeHV-1 by a VN assay. The serum samples came from cats admitted in veterinary clinics, household cats and cats examined in veterinary hospitals at three universities from Rio Grande do Sul State (RS) [UFRGS, UFSM and UPF]. The serum samples were classified according to the origin, gender, age and vaccination status of the cat. All animal handling procedures were performed under veterinary supervision and following the recommendations of the Brazilian Committee on Animal Experimentation. The feline cell line CRFK (Crandell-Rees feline kidne

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemic disease (FCV-VSD), which has not yet been reported in Brazil. The aim of the present study was to investigate the presence of antibodies against FCV and FeHV-1 in the population of domestic felines from some counties of the Rio Grande do Sul State (RS), using a virus neutralizing (VN) assay. Materials, Methods & Results: A total of 630 feline serum samples collected between the years 2007 and 2011 were analyzed to detect antibodies against FCV and FeHV-1 by a VN assay. The serum samples came from cats admitted in veterinary clinics, household cats and cats examined in veterinary hospitals at three universities from Rio Grande do Sul State (RS) [UFRGS, UFSM and UPF]. The serum samples were classified according to the origin, gender, age and vaccination status of the cat. All animal handling procedures were performed under veterinary supervision and following the recommendations of the Brazilian Committee on Animal Experimentation. The feline cell line CRFK (Crandell-Rees feline kidne

RESUMO

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemic disease (FCV-VSD), which has not yet been reported in Brazil. The aim of the present study was to investigate the presence of antibodies against FCV and FeHV-1 in the population of domestic felines from some counties of the Rio Grande do Sul State (RS), using a virus neutralizing (VN) assay. Materials, Methods & Results: A total of 630 feline serum samples collected between the years 2007 and 2011 were analyzed to detect antibodies against FCV and FeHV-1 by a VN assay. The serum samples came from cats admitted in veterinary clinics, household cats and cats examined in veterinary hospitals at three universities from Rio Grande do Sul State (RS) [UFRGS, UFSM and UPF]. The serum samples were classified according to the origin, gender, age and vaccination status of the cat. All animal handling procedures were performed under veterinary supervision and following the recommendations of the Brazilian Committee on Animal Experimentation. The feline cell line CRFK (Crandell-Rees feline kidne

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemic disease (FCV-VSD), which has not yet been reported in Brazil. The aim of the present study was to investigate the presence of antibodies against FCV and FeHV-1 in the population of domestic felines from some counties of the Rio Grande do Sul State (RS), using a virus neutralizing (VN) assay. Materials, Methods & Results: A total of 630 feline serum samples collected between the years 2007 and 2011 were analyzed to detect antibodies against FCV and FeHV-1 by a VN assay. The serum samples came from cats admitted in veterinary clinics, household cats and cats examined in veterinary hospitals at three universities from Rio Grande do Sul State (RS) [UFRGS, UFSM and UPF]. The serum samples were classified according to the origin, gender, age and vaccination status of the cat. All animal handling procedures were performed under veterinary supervision and following the recommendations of the Brazilian Committee on Animal Experimentation. The feline cell line CRFK (Crandell-Rees feline kidne

RESUMO

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemic disease (FCV-VSD), which has not yet been reported in Brazil. The aim of the present study was to investigate the presence of antibodies against FCV and FeHV-1 in the population of domestic felines from some counties of the Rio Grande do Sul State (RS), using a virus neutralizing (VN) assay. Materials, Methods & Results: A total of 630 feline serum samples collected between the years 2007 and 2011 were analyzed to detect antibodies against FCV and FeHV-1 by a VN assay. The serum samples came from cats admitted in veterinary clinics, household cats and cats examined in veterinary hospitals at three universities from Rio Grande do Sul State (RS) [UFRGS, UFSM and UPF]. The serum samples were classified according to the origin, gender, age and vaccination status of the cat. All animal handling procedures were performed under veterinary supervision and following the recommendations of the Brazilian Committee on Animal Experimentation. The feline cell line CRFK (Crandell-Rees feline kidney) was used for viral amplification and for the VN assay. The viruses used in the assay were the isolate SV65/90 of FCV, and the isolate SV534/00 of FeHV-1, from the Setor de Virologia/ UFSM; which were well characterized in a previous study by our group. The serum samples were tested against 100-200 TCID 50/mL (tissue cellular infection dose 50/mL) of both viruses in the VN assay, and a serial dilution of the serum was performed, starting at 1:5 up to > 1:1280 for FCV and at 1:2 to > 1:256 for FeHV-1 in 96 wells plates. Neutralization titers were calculated as the reciprocal of the highest serum dilution able to inhibit the cytopathic effect. Concerning to the results obtained, the groups with the highest number of collected samples were the group of the male cats (44%, 277/630), the group of the cats with ages among one to five years old (36.3%, 229/630) and the group of non-vaccinated cats (94%, 592/630). Neutralizing antibodies against one or both viruses were detected in 53.6% (338/630) of the 630 cats sampled; 23% (145/630) of the cats were seropositive only to FCV, 14.4% (91/630) were seropositive only to FeHV-1 and 16.2% (102/630) were seropositive for both, FCV and FeHV1. Regarding the groups, a higher percentage of positive samples was found for the group of female cats (85.6%) and the group of cats over fi ve years old for both viruses (82.3%). Considering vaccination status, only 6% of the cats were vaccinated against FCV and/or FeHV-1, however not all vaccinated cats had neutralizing antibodies against the viruses, since only 50% of the vaccinated population were seropositive against FCV and 42.1% of them were seropositive for FeHV-1. Discussion: The data showed in the present study demonstrated that both viruses are circulating in the feline population sampled; and, it also revealed that FCV seems to be more prevalent among this population since the presence of antibodies against FCV were detected more frequently than antibodies against FeHV-1. The high number of non-reagent serum and non-vaccinated cats indicates that there is yet a large percentage of the cat population that is susceptible to infection. The application of vaccination programs according of the recommendations could help to prevent the infection and change the situation among the feline population sampled.

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