RESUMO

BACKGROUND: Evidence has suggested that cognitive decline may be a risk factor for freezing of gait (FOG) in Parkinson's disease (PD). Complex and challenging exercises have been suggested as potential rehabilitation strategies to decrease FOG severity and improve cognition; however, it is unknown whether improvement in cognition would explain decreased FOG severity following exercise. OBJECTIVE: In this secondary analysis, we evaluated the effects of the adapted resistance training with instability (ARTI-complex and challenging exercises) compared with traditional motor rehabilitation (TMR-without challenging exercises) on cognitive function in people with FOG of PD. We also verified whether cognitive improvement explains the decrease in FOG previously published. METHODS: Participants were randomized to either the experimental group (ARTI, n = 17) or the active control group (TMR, n = 15). Both training groups exercised 3 times a week for 12 weeks (80-90 minute each session). FOG severity (FOG ratio from inertial sensors during a 360° turning-in-place task), frontal lobe function (Frontal Assessment Battery [FAB]), global cognition (Montreal Cognitive Assessment [MoCA]), and attention and psychomotor speed (Digit Symbol Substitution Test [DSST]) were evaluated before and after interventions. RESULTS: Only the ARTI group improved FAB, MoCA, and DSST scores at posttraining. In addition, ARTI was more effective than TMR in improving FAB scores at posttraining. The changes in FAB scores explained the changes in FOG ratio following ARTI (R2 = .43, P < .01). CONCLUSIONS: This pilot study suggests that ARTI, a complex and challenging training, improves cognition in people with FOG of PD. Improvements in frontal lobe function with ARTI help explain decreased FOG severity.

RESUMO

Resumen La psicología y las neurociencias ofrecen nuevas perspectivas para comprender el comportamiento económico y del consumidor. La neuroeconomía provee un nuevo marco de referencia para comprender la forma en la que las estructuras neuroanatómicas del cerebro se encuentran implicadas en las decisiones financieras de los individuos. En este contexto, el objetivo de la investigación es identificar la asociación entre la inhibición cognitiva y la cantidad de dinero que gastan los universitarios. Participaron 40 jóvenes universitarios, 47.5 % hombres y 52.5 % mujeres, entre 18 y 25 años, de la Ciudad de Querétaro, México. La inhibición cognitiva se evaluó con el Test de Stroop. Además, se preguntó sobre datos sociodemográficos y los gastos mensuales. Los resultados muestran descriptivamente el nivel de gasto de los jóvenes y las puntuaciones del efecto Stroop. Los jóvenes tienen puntuaciones medias en Palabra, Color, Palabra - Color e Interferencia, acorde a los parámetros establecidos. Respecto al gasto mensual se observa que, en promedio, gastan $ 666 pesos mexicanos (34.04 USD / 31.13 EUR). Adicionalmente, se encontró un déficit en el control inhibitorio relacionado con un aumento en el nivel de gasto realizado por los estudiantes universitarios, es decir, aquellos que gastan y compran, en mayor medida presentan dificultades en su inhibición cognitiva (autocontrol). El control inhibitorio se asoció con la edad y esta, a su vez, con el nivel de dinero gastado. Por último, se profundiza en la utilidad de los resultados dentro de la neuroeconomía en México y demás países latinoamericanos, así como su aporte como línea de investigación.

Abstract Psychology and neuroscience offer new perspectives to understand consumer and economic behaviour. Neuroeconomics provides a new frame of reference to understand the way in which the neuroanatomical structures of the brain are involved in the financial decisions of people. Currently, measurement scales are an application alternative to assess people's executive functions and cognitive inhibition quickly. In the present study for the evaluation of cognitive inhibition we will use the Stroop Test (Golden, 1994), which examines the cognitive processes associated with cognitive flexibility; the interference resistance from external stimuli and its effect on behaviour. The plates that make up the Stroop test present different possibilities for analysis and interpretation. Within neuroeconomics, there is an area that investigates how cognitive and affective regulation is critical to achieve economic results, in addition to investigating the problems caused by consumption and spending that people have in their daily lives. There is research shown that individuals who make compulsive purchases show cognitive deficiencies and difficulties in inhibiting their responses. Furthermore, compulsive purchases correlate with financial executive functioning, particularly with impulse control, organization and planning, showing that compulsive purchases are not limited only to impulse control. In Latin America and particularly in Mexico, there are few studies on neuroeconomics or consumer neuroscience, so consider that this research is an innovative contribution to the subject in our region. In this context, the objective of the research is to identify the association between cognitive inhibition and the money university students spend. This research evaluated the association between cognitive inhibition and the money university students spend. A total of 40 university students participated, 47.5 % men and 52.5 % women, between 18 and 25 years, from the City of Querétaro, Mexico. Cognitive inhibition was evaluated with the Stroop Test. In addition, sociodemographic data and monthly expenses were asked. The results descriptively detailed the level of youth spending and the Stroop effect variables. Young people have mean scores in Word, Colour, Word - Colour and Interference, according to the established parameters. Regarding monthly expenses, it is observed that on average they spend $ 666 Mexican pesos (34.04 USD / 31.13 EUR). In addition, a deficit was found in the inhibitory control related to an increase in the level of expenditure made by university students, that is, those who spend and buy more have difficulties in their cognitive inhibition (self-control). Inhibitory control is associated with age and this time with the level of money spent. Additionally, the inhibition processes allows us to assume certain activity in the orbitofrontal cortex (OFC) and the dorsolateral prefrontal cortex (DLFC), while they are ready to spend and who has problems with the control of their money, they cannot realize the excessive expenses that it does not recognize the symptoms that drive it to compulsive buying. The findings provide evidence to the neuroeconomy, as well as to the posture of cognitive control. Furthermore, it is corroborated that performance tests are an alternative in the detection of executive functioning deficiencies in a short time of application and provide evidence in the approach to neuroeconomics through this form of measurement. This offers a novel vision to understand the personal finances of Mexicans and their economic behaviour. Financial and consumer behaviour has become our main line of research from a neuroeconomic perspective; in the future, we intend to continue this study by incorporating affective and neurobehavioral factors involved in financial decisions in young people of our country. Finally, the usefulness of the results within the neuroeconomics in Mexico and Latin America is deepened, as well as its contribution as a line of research.

RESUMO

Inhibition constitutes one of the main executive functions and it is important to more complex skills such as fluid intelligence. Actually, there is an agreement on distinguishing three inhibitory types: perceptual, cognitive and response inhibition. Several studies show the differential engagement of these inhibitory types in different skills. However, there is no registered evidence about the differential relation of inhibitory types with fluid intelligence. This inquiry is especially important during the first school years, since in this stage, inhibitory processes would already be differentiated, and inhibitory processes and fluid intelligence are linked to the performance of children in the school setting. For these reasons, the goal of this work is to study the relation and contribution of perceptual, cognitive, and response inhibition with fluid intelligence, in children in the first years of primary school. For that purpose, a sample of children from six to eight years old (N = 178) was tested with a perceptual inhibition task (perception of similarities and differences task); a cognitive inhibition task (proactive interference task); a response inhibition task (stop signal task); and a fluid intelligence task (progressive matrices task). We observed significant correlations between perceptual and response inhibition and fluid intelligence (controlling for age), but only perceptual inhibition explains significantly part of the performance in the fluid intelligence task. This study provides data about the specific contribution, during childhood, of an inhibitory type to fluid intelligence and contributes empirical evidence in support of the non-unitary approach of inhibition.

La inhibición constituye una de las principales funciones ejecutivas, siendo fundamental para otras habilidades más complejas, tales como la inteligencia fluida. Actualmente, existe acuerdo en distinguir tres procesos inhibitorios: inhibición perceptual, cognitiva y de la respuesta. Distintos estudios muestran que los tipos inhibitorios participan de manera diferencial en diversas habilidades, aunque no se registra evidencia sobre la relación diferencial de los mismos con la inteligencia fluida. Su estudio es especialmente importante durante los primeros años de la escuela primaria, donde los procesos inhibitorios estarían diferenciados y tanto ellos como la inteligencia fluida se vinculan con el desempeño de los niños en el ámbito escolar. Por estos motivos, este trabajo se propuso analizar la relación y contribución de la inhibición perceptual, cognitiva y de la respuesta con la inteligencia fluida en niños en los primeros años de la escuela primaria. Para ello, una muestra de niños de seis a ocho años de edad (N = 178) fue evaluada con una tarea de inhibición perceptual (test de percepción de diferencias y similitudes), una tarea de inhibición cognitiva (tarea de interferencia proactiva), una tarea de inhibición de la respuesta (basada en el paradigma stop signal ) y una tarea de inteligencia fluida (test de matrices progresivas). Se encontraron correlaciones significativas entre la inhibición perceptual y de la respuesta con la inteligencia fluida (controlando la edad), pero solo la inhibición perceptual explica de manera significativa parte del rendimiento en la tarea de inteligencia fluida. Este estudio aporta datos específicos sobre la contribución de un tipo inhibitorio a la inteligencia fluida durante la niñez, así como evidencia empírica a favor del modelo no-unitario de la inhibición.

RESUMO

BACKGROUND: Exercises with motor complexity induce neuroplasticity in individuals with Parkinson's disease (PD), but its effects on freezing of gait are unknown. The objective of this study was to verify if adapted resistance training with instability - exercises with motor complexity will be more effective than traditional motor rehabilitation - exercises without motor complexity in improving freezing-of-gait severity, outcomes linked to freezing of gait, and brain function. METHODS: Freezers were randomized either to the adapted resistance training with instability group (n = 17) or to the active control group (traditional motor rehabilitation, n = 15). Both training groups performed exercises 3 times a week for 12 weeks. The primary outcome was the New Freezing of Gait Questionnaire. Secondary outcomes were freezing of gait ratio (turning task), cognitive inhibition (Stroop-III test), motor signs (Unified Parkinson's Disease Rating Scale part-III [UPDRS-III]), quality of life (PD Questionnaire 39), anticipatory postural adjustment (leg-lifting task) and brain activation during a functional magnetic resonance imaging protocol of simulated anticipatory postural adjustment task. Outcomes were evaluated before and after interventions. RESULTS: Only adapted resistance training with instability improved all the outcomes (P < 0.05). Adapted resistance training with instability was more effective than traditional motor rehabilitation (in improving freezing-of-gait ratio, motor signs, quality of life, anticipatory postural adjustment amplitude, and brain activation; P < 0.05). Our results are clinically relevant because improvement in the New Freezing of Gait Questionnaire (-4.4 points) and UPDRS-III (-7.4 points) scores exceeded the minimally detectable change (traditional motor rehabilitation group data) and the moderate clinically important difference suggested for PD, respectively. The changes in mesencephalic locomotor region activation and in anticipatory postural adjustment amplitude explained the changes in New Freezing of Gait Questionnaire scores and in freezing-of-gait ratio following adapted resistance training with instability, respectively. CONCLUSIONS: Adapted resistance training with instability is able to cause significant clinical improvement and brain plasticity in freezers. © 2020 International Parkinson and Movement Disorder Society.

Assuntos

RESUMO

We studied cognitive inhibitory processes and verbal regulation of behavior of individuals with different levels of education (including adult illiterates) in Brazil (N = 136) and in Estonia (N = 560) with person-oriented methods of data analysis. Our aim was to discover whether dominant type of word meaning structure (WMS) can define the "Great Divide", the single breaking point that universally defines certain direction of subsequent to it cultural evolution. We found that both cognitive inhibition of irrelevant for the task at hand information or actions as well as correct activation of relevant information or actions is significantly more common in individuals who rely predominantly on logical concepts in their thinking. The higher level of education was also associated with more efficient cognitive inhibition and activation. The patterns of test performance also suggest that there can be a qualitative difference in the efficiency of cognitive inhibition-activation processes between everyday conceptual and logical conceptual thinkers. The former group of individuals may achieve much higher performance levels than any individual in the former group. We also discuss cognitive similarities and differences between adults with low or no formal education on the one hand and children and educated adults with brain damage on the other. The results are in agreement with the theory of unilineal hierarchic cultural evolution. Individual psychic development and cultural evolution can be both understood in terms of the WMS development.

Assuntos

RESUMO

La inhibición y la flexibilidad cognitiva son funciones ejecutivas principales, mientras la primera aportaría al funcionamiento de la segunda. Actualmente, se identifican distintos procesos inhibitorios -inhibición perceptual, cognitiva y de la respuesta- que presentarían relaciones diferenciales con diversas habilidades. Sin embargo, no se registran estudios sobre tales relaciones con la flexibilidad cognitiva durante los primeros años escolares, donde estas funciones están en desarrollo y contribuyen con el desempeño escolar. Este trabajo se propuso estudiar la relación y contribución de cada proceso inhibitorio a la flexibilidad cognitiva en niños escolares de 6 a 8 años. Los participantes (N=171) efectuaron tareas inhibitorias y de flexibilidad cognitiva. Los resultados muestran una relación baja entre la inhibición perceptual y la flexibilidad cognitiva y ausencia de relaciones con los otros procesos inhibitorios. Ello aporta evidencia al modelo no-unitario de la inhibición y permite discutir sobre la relación de los procesos durante el desarrollo(AU)

Inhibition and cognitive flexibility are basic executive functions, and inhibition would contribute to performance of cognitive flexibility. Actually, different inhibitory processes are identified ­perceptual, cognitive and response inhibition. They engagement differentially in diverse skills; however, studies about differential relationships between inhibitory processes and cognitive flexibility during first years of school period are not registered. At this stage, all of these functions are in development and are essential for children's academic performance. The goal of this work is to study the relation and contribution of each inhibitory process with the cognitive flexibility, in scholar children from 6 to 8 years-old. The participants (N=171) carried out inhibitory and cognitive flexibility tasks. The results show low relation between perceptual inhibition and cognitive flexibility, and absence of relations with other inhibitory processes. The study contributes evidence in support of the non-unitary approach of inhibition, and allows discuss about relationships between these functions during the development(AU)

Assuntos

RESUMO

Resumen La atención selectiva es la función cognitiva que orienta la atención hacia los objetos o estímulos que resultan relevantes evitando la distracción frente a aquellos que son irrelevantes. En general, la literatura indica que el desempeño de la atención selectiva mejora notablemente con la edad, sin embargo, las diferencias vinculadas a esta variable no se cumplen para todas las condiciones de cantidad de estímulos distractores ni para todos los grupos de edad. Asimismo, aún no se ha explorado la contribución del control inhibitorio y la velocidad de procesamiento a esta mejora progresiva. Por este motivo, y debido a la escasez de estudios en población infantil, se propuso analizar la contribución relativa de la velocidad de procesamiento y de la inhibición al desempeño en una tarea de atención selectiva y búsqueda visual en esta etapa evolutiva. Para ello, se administró una tarea de búsqueda de conjunciones y una tarea simple de velocidad de respuesta a 295 niños de 6 a 13 años de edad. Los resultados permitieron plantear dos conclusiones principales: por un lado, que la atención selectiva mejora consistentemente durante la niñez y, por otro lado, que no existe un mecanismo general y exclusivo capaz de explicar estas diferencias durante esta etapa vital. Así, tanto la velocidad de procesamiento como el control inhibitorio contribuyen al desarrollo de la atención selectiva y ambos mecanismos cognitivos actúan de manera complementaria más que excluyente.

Abstract Selective attention allows directs attention to relevant objects or stimuli, while avoiding distraction from those that are irrelevant. The literature indicates that performance in CVS tasks improves markedly with age. However, age-related differences are not met neither for every number of distractor conditions nor for all age groups. In addition, the contribution of inhibitory control and processing speed to this progressive improvement has not yet been explored. For this reason, and due to the scarcity of studies using CVS paradigm to evaluate selective attention in children, the present study aimed to analyze the relative contribution of processing speed and inhibition to performance during this evolutionary period in a selective attention and CVS task. To do this, a CVS and a simple response speed task were administered to 295 children aged 6-13 years old. Results offered two conclusions: first, selective attention improves during childhood; second, there is no general and exclusive mechanism capable of explaining these differences during this period. Thus, both processing speed and inhibitory control contribute to development of selective attention, and they seem to be more complementary mechanisms than excluding ones.