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1.
Acta sci. vet. (Online) ; 47(suppl.1): Pub. 434, Oct. 27, 2019. ilus
Artigo em Inglês | VETINDEX | ID: vti-25727

RESUMO

Background: Although testicular tumors commonly develop in the genital tract of dogs, only few studies have reportedabout metastatic testicular tumors in dogs to date. Therefore, the present study aimed to describe the gross, histopathological, and immunohistochemical findings in a dog with metastatic interstitial cell tumor.Case: A 6-year-old male Beagle underwent clinical examination due to enlargement of the left testicle and nodules inthe skin of the left inguinal region and of the scrotum. The left testicle was cryptorchid (inguinal), and the right testiclewas intrascrotal. Both testicles and affected skin fragments were surgically removed. The right testicle was normal insize and did not exhibit gross changes. However, the left testicular parenchyma had been completely replaced by a firm,grayish-to-white neoplastic mass with an irregular surface. The inguinal and scrotal skin fragments were thickened by theneoplastic masses. Histologically, the left testicular parenchyma was completely obliterated by a neoplastic mass consistingof round-to-oval and polygonal cells. The neoplastic cells generally had abundant eosinophilic cytoplasm with indistinctcell limits. The nuclei were round and small, with aggregated chromatin. However, some cells exhibited high degrees ofatypia and pleomorphism and large nuclei with granular chromatin. Mitotic figures were observed at high frequenciesof up to 11 per high-power field (400×). The mass in the left testicle was diagnosed as malignant interstitial cell tumor.The sections of the inguinal skin and scrotum presented with neoplastic cells similar to those observed in the left testicle,which is consistent with the metastasis of the malignant testicular interstitial cell tumor. On the basis of necropsy, multiple cutaneous and subcutaneous nodules were randomly distributed throughout the body, primarily in the prepuce, head,and limbs. Histological evaluations of the skin nodules...(AU)


Assuntos
Animais , Masculino , Cães , Tumor de Células de Leydig/patologia , Tumor de Células de Leydig/veterinária , Neoplasias Testiculares/veterinária , Metástase Neoplásica , Neoplasias Cutâneas/veterinária , Imuno-Histoquímica/veterinária
2.
Acta sci. vet. (Impr.) ; 47(suppl.1): Pub.434-2019. ilus
Artigo em Inglês | VETINDEX | ID: biblio-1458198

RESUMO

Background: Although testicular tumors commonly develop in the genital tract of dogs, only few studies have reportedabout metastatic testicular tumors in dogs to date. Therefore, the present study aimed to describe the gross, histopathological, and immunohistochemical findings in a dog with metastatic interstitial cell tumor.Case: A 6-year-old male Beagle underwent clinical examination due to enlargement of the left testicle and nodules inthe skin of the left inguinal region and of the scrotum. The left testicle was cryptorchid (inguinal), and the right testiclewas intrascrotal. Both testicles and affected skin fragments were surgically removed. The right testicle was normal insize and did not exhibit gross changes. However, the left testicular parenchyma had been completely replaced by a firm,grayish-to-white neoplastic mass with an irregular surface. The inguinal and scrotal skin fragments were thickened by theneoplastic masses. Histologically, the left testicular parenchyma was completely obliterated by a neoplastic mass consistingof round-to-oval and polygonal cells. The neoplastic cells generally had abundant eosinophilic cytoplasm with indistinctcell limits. The nuclei were round and small, with aggregated chromatin. However, some cells exhibited high degrees ofatypia and pleomorphism and large nuclei with granular chromatin. Mitotic figures were observed at high frequenciesof up to 11 per high-power field (400×). The mass in the left testicle was diagnosed as malignant interstitial cell tumor.The sections of the inguinal skin and scrotum presented with neoplastic cells similar to those observed in the left testicle,which is consistent with the metastasis of the malignant testicular interstitial cell tumor. On the basis of necropsy, multiple cutaneous and subcutaneous nodules were randomly distributed throughout the body, primarily in the prepuce, head,and limbs. Histological evaluations of the skin nodules...


Assuntos
Masculino , Animais , Cães , Metástase Neoplásica , Neoplasias Cutâneas/veterinária , Neoplasias Testiculares/veterinária , Tumor de Células de Leydig/patologia , Tumor de Células de Leydig/veterinária , Imuno-Histoquímica/veterinária
3.
Rev. cuba. med. gen. integr ; 34(2)abr.-jun. 2018. ilus
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1093438

RESUMO

Introducción: Conocemos como microlitiasis testicular a la afección en la cual se da la formación de calcificaciones en el interior del testículo. Su etiología es desconocida, y presenta mayor prevalencia en la edad adulta que en la pediátrica. Esta patología muestra su diagnóstico por medio de estudios imagenológicos. Caso clínico: Paciente de 17 años, el cual acude por dolor pélvico de un mes de evolución, y al cual se le diagnostica esta entidad tras los estudios complementarios. En el siguiente estudio se realiza una revisión bibliográfica de los aspectos relevantes de la patología y tratamiento, así como, la relación que existe entra la microlitiasis testicular y la neoplasia de testículo, infertilidad y patologías de base genética, tópicos de sumo interés para el médico general de atención en nivel primario de salud, considerando el manejo de control y prevención que debe aplicarse día a día en la consulta médica. Conclusiones: El conocimiento de las complicaciones que podrían presentarse en el paciente portador de microlitiasis testicular, obligan al médico a mostrar una actitud prudente ante esta patología, considerando el aspecto preventivo de la atención primaria de salud(AU)


Introducción: Conocemos como microlitiasis testicular a la afección en la cual se da la formación de calcificaciones en el interior del testículo. Su etiología es desconocida, y presenta mayor prevalencia en la edad adulta que en la pediátrica. Esta patología muestra su diagnóstico por medio de estudios imagenológicos.m Caso clínico: Paciente de 17 años, el cual acude por dolor pélvico de un mes de evolución, y al cual se le diagnostica esta entidad tras los estudios complementarios. En el siguiente estudio se realiza una revisión bibliográfica de los aspectos relevantes de la patología y tratamiento, así como, la relación que existe entra la microlitiasis testicular y la neoplasia de testículo, infertilidad y patologías de base genética, tópicos de sumo interés para el médico general de atención en nivel primario de salud, considerando el manejo de control y prevención que debe aplicarse día a día en la consulta médica. Conclusiones: El conocimiento de las complicaciones que podrían presentarse en el paciente portador de microlitiasis testicular, obligan al médico a mostrar una actitud prudente ante esta patología, considerando el aspecto preventivo de la atención primaria de salud(AU)


Assuntos
Humanos , Masculino , Adolescente , Atenção Primária à Saúde , Neoplasias Testiculares/complicações , Neoplasias Testiculares/diagnóstico , Neoplasias Testiculares/epidemiologia , Ultrassonografia/métodos
4.
Acta sci. vet. (Impr.) ; 46(supl): 1-7, 2018. ilus
Artigo em Português | VETINDEX | ID: biblio-1457961

RESUMO

Background: In dogs, abdominal testes have higher risk of malignant transformation, and the Sertoli cell tumor is the most common type of testicular cancer in the species. This neoplasia can lead to an increase on estrogen production, causing a paraneoplastic feminization syndrome with dermatologic, behavioral and blood repercussions. When located inside the abdomen, the Sertoli cell tumor can compress adjacent organs, worsening the prognosis. Thus, this study aimed to report a case of an intra-abdominal Sertoli cell tumor in a dog associated to multiple organic complications.Case: A 4-year-old male Shih-tzu was admitted at the Veterinary Hospital of Universidade Federal Rural do Semi-Árido (UFERSA), with a history of abdominal cryptorchidism and the development of dermatological signs, such as alopecia and hyperpigmentation, with an evolution of two months. At physical examination it was observed alopecia on lumbosacral region and on hind limbs, hyperpigmentation, gynecomastia and pendulous prepuce, suggestive of feminization syndrome. A firm mass was palpated on caudal abdomen. The following exams were requested: complete blood cell count, serum biochemistry (alanine aminotransferase, alkaline phosphatase, creatinine and urea), abdominal ultrasonography and fine needle aspiration cytology of the abdominal mass. Hematological and biochemistry profile were within the normal range for the species. On the ultrasonography, regular and rounded structures were observed, suggesting ectopic testes (left testis: 2.37 x 2.95 cm; right testis: 1.92 x 1.38 cm). The left testis presented characteristics of malignant transformation. The cytology of the abdominal mass suggested Sertoli cell tumor. The dog was submitted to an exploratory laparotomy. The right testis was atrophied and its orchiectomy was performed.[...]


Assuntos
Masculino , Animais , Cães , Neoplasias Testiculares/veterinária , Tumor de Células de Sertoli/complicações , Tumor de Células de Sertoli/diagnóstico por imagem , Tumor de Células de Sertoli/veterinária , Criptorquidismo/complicações , Criptorquidismo/veterinária
5.
Acta sci. vet. (Online) ; 46(supl): 1-7, 2018. ilus
Artigo em Português | VETINDEX | ID: vti-19011

RESUMO

Background: In dogs, abdominal testes have higher risk of malignant transformation, and the Sertoli cell tumor is the most common type of testicular cancer in the species. This neoplasia can lead to an increase on estrogen production, causing a paraneoplastic feminization syndrome with dermatologic, behavioral and blood repercussions. When located inside the abdomen, the Sertoli cell tumor can compress adjacent organs, worsening the prognosis. Thus, this study aimed to report a case of an intra-abdominal Sertoli cell tumor in a dog associated to multiple organic complications.Case: A 4-year-old male Shih-tzu was admitted at the Veterinary Hospital of Universidade Federal Rural do Semi-Árido (UFERSA), with a history of abdominal cryptorchidism and the development of dermatological signs, such as alopecia and hyperpigmentation, with an evolution of two months. At physical examination it was observed alopecia on lumbosacral region and on hind limbs, hyperpigmentation, gynecomastia and pendulous prepuce, suggestive of feminization syndrome. A firm mass was palpated on caudal abdomen. The following exams were requested: complete blood cell count, serum biochemistry (alanine aminotransferase, alkaline phosphatase, creatinine and urea), abdominal ultrasonography and fine needle aspiration cytology of the abdominal mass. Hematological and biochemistry profile were within the normal range for the species. On the ultrasonography, regular and rounded structures were observed, suggesting ectopic testes (left testis: 2.37 x 2.95 cm; right testis: 1.92 x 1.38 cm). The left testis presented characteristics of malignant transformation. The cytology of the abdominal mass suggested Sertoli cell tumor. The dog was submitted to an exploratory laparotomy. The right testis was atrophied and its orchiectomy was performed.[...](AU)


Assuntos
Animais , Masculino , Cães , Tumor de Células de Sertoli/complicações , Tumor de Células de Sertoli/diagnóstico por imagem , Tumor de Células de Sertoli/veterinária , Neoplasias Testiculares/veterinária , Criptorquidismo/complicações , Criptorquidismo/veterinária
6.
Horiz. méd. (Impresa) ; 17(1): 66-71, ene.-mar. 2017. ilus
Artigo em Espanhol | LILACS | ID: biblio-989898

RESUMO

La leucemia linfoblástica aguda es una neoplasia predominante en pediatría, corresponde al 11% de las leucemias. En Colombia hay una incidencia anual en adultos de 1 por cada 100.000 habitantes. La recaída testicular es rara alcanzando solo del 0.9 a 8.8% de todos los casos y representa un signo de recurrencia que puede ser confundida con otros padecimientos testiculares. Se reporta el caso de un paciente masculino de 23 años de edad, con cuadro de 2 meses de evolución consistente en dolor y aumento de tamaño testicular, posterior a trauma, con antecedente de leucemia linfoblástica aguda tratada hace 4 años. Se realiza ecografía testicular que sugiere hidrocele a tensión. Es llevado a cirugía, donde se aprecia testículo con características neoplásicas por lo cual se realiza orquiectomía. Resultado de anatomía patológica concluye masa 12 cm correspondiente a infiltración por leucemia aguda, CD10 y CD34 positivo y Tdt negativo. El testículo es considerado santuario de células leucémicas, sin embargo excepcionalmente puede observarse formación de una masa simulando un tumor testicular


Acute lymphoblastic leukemia is a common pediatric neoplasia, comprising 11% of all leukemias. In Colombia, the annual incidence in adults is 1 out of 100,000 people. Testicular relapse is rare (accounting for only 0.9-8.8% of all cases) and represents a sign of recurrence which can be confused with other testicular conditions. We report the case of a 23-year- old male with testicular pain and swelling for 2 months after a trauma, and a history of acute lymphoblastic leukemia treated 4 years before. A testicular ultrasound suggested tension hydrocele. The patient was taken to surgery where a testis with neoplastic features was observed. Therefore, an orchiectomy was performed. The pathological anatomy revealed a 12-cm mass consisting of infiltration by leukemic cells, showing a positive expression for CD19, CD10, and a negative expression for TdT. The testes are considered a sanctuary site for leukemic cells. However, the formation of a mass that mimic a testicular tumor may exceptionally be observed

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