RESUMO
Introducción: La lesión por quemadura es uno de los eventos más traumáticos y devastadores que puede sufrir un ser humano. Este evento térmico produce profundas alteraciones en los mecanismos sistémicos de defensa del huésped. Las complicaciones en grandes quemados comienzan en la fase inmediata de la inflamación producida tras sufrir la agresión térmica. Las complicaciones en los pacientes quemados se han asociado con un mal pronóstico, con una alta morbilidad y mortalidad. Objetivo: Describir las complicaciones en los pacientes quemados. Métodos: Se realizó un estudio descriptivo, retrospectivo, de corte transversal para describir las complicaciones en los pacientes quemados que ingresaron en la sala de Caumatología del Hospital Universitario Manuel Ascunce Domenech de la ciudad Camagüey en el período comprendido desde enero de 2021 hasta febrero de 2022. Se estudiaron 32 pacientes en quienes se tuvieron en cuenta las variables: índice de gravedad, complicaciones generales, las complicaciones hidroelectrolíticas y acido básicas, así el estado al egreso de los pacientes. Resultados: Hubo un predominio de pacientes con complicaciones en aquellos lesionados con insulto térmico severo, presentes en 24 pacientes para un 75 %. La infección de la lesión por quemaduras, la hiperglucemia, la anemia y los estados de deshidratación fueron las complicaciones que mayormente se presentaron en los pacientes estudiados. La totalidad de los fallecidos fueron del grupo de pacientes que presentaron complicaciones, ocho pacientes para un 25 %. Conclusiones: La infección de las quemaduras es la principal complicación del paciente quemado. La mayoría de los pacientes de esta serie egresaron vivos.
Introduction: Burn injury is one of the most traumatic and devastating events that a human being can suffer. This thermal event produces profound alterations in the host's systemic defense mechanisms. Complications in major burns begin in the immediate phase of inflammation produced after suffering thermal aggression. Complications in the burned patients are associated with a bad prognosis with a high morbility and mortality. Objective: To decribe the complications in burned patient. Methods: A descriptive, retrospective, cross-section study was carried out to determine the complications in the burned patients that were admitted in the service of Caumatology, of the Universitary Hospital Manuel Ascunce Domenech in Camagüey city between January, 2021 and February, 2022. 32 patients were studied and the following variables were evaluated: severity rate, general complications, and acid-basic and hydroelectrolytic complications, as well as the state at discharge of the patients. Results: There was a predominance of patients with complications, in those injured persons with thermic harsh insult, present in 24 patients for 75 %. The infection of the injury for burns, the hyperglycemia, the anemia and the states of dehydration were the complications that largely showed up in the studied patients. All of the dead persons belonged to patient's group that had complications, eight patients showed (25 %). Conclusions: The infection of the burns continues to be the main complication of the burned patient. Most of the patients in this series were discharged alive.
RESUMO
Abstract Objective: To identify risk factors for chronic kidney disease progression in Brazilian children and to evaluate the interactions between factors. Methods: This was a multicenter prospective cohort in São Paulo, involving 209 children with CKD stages 3-4. The study outcome included: (a) death, (b) start of kidney replacement therapy, (c) eGFR decrease >50% during the followup. Thirteen risk factors were tested using univariate regression models, followed by multivariable Cox regression models. The terms of interaction between the variables showing significant association with the outcome were then introduced to the model. Results: After a median follow-up of 2.5 years (IQR = 1.4-3.0), the outcome occurred in 44 cases (21%): 22 started dialysis, 12 had >50% eGFR decrease, seven underwent transplantation, and three died. Advanced CKD stage at onset (HR = 2.16, CI = 1.14-4.09), nephrotic proteinuria (HR = 2.89, CI = 1.49-5.62), age (HR = 1.10, CI = 1.01-1.17), systolic blood pressure Z score (HR = 1.36, CI = 1.08-1.70), and anemia (HR = 2.60, CI = 1.41-4.77) were associated with the outcome. An interaction between anemia and nephrotic proteinuria at V1 (HR = 0.25, CI = 0.06-1.00) was detected. Conclusions: As the first CKD cohort in the southern hemisphere, this study supports the main factors reported in developed countries with regards to CKD progression, affirming the potential role of treatments to slow CKD evolution. The detected interaction suggests that anemia may be more deleterious for CKD progression in patients without proteinuria and should be further studied.
Resumo Objetivo: Identificar os fatores de risco para progressão da DRC em crianças do Brasil e avaliar as interações entre os fatores. Métodos: Coorte prospectiva multicêntrica em São Paulo, envolvendo 209 crianças com DRC em estágios 3-4. O desfecho do estudo incluiu: a) óbito, b) início da terapia de substituição renal, c) redução de > 50% na taxa estimada de filtração glomerular (eGFR) durante o acompanhamento. Foram testados 13 fatores de risco com o modelo de regressão univariada seguido do modelo de regressão multivariado de Cox. Os termos de interação entre as variáveis mostraram associação significativa e foram introduzidos ao modelo. Resultados: Após média de acompanhamento de 2,5 anos (IIQ = 1,4 a 3,0), 44 casos (21%) apresentaram desfecho: 22 iniciaram diálise, 12 apresentaram redução de > 50% na eGFR, sete foram submetidos a transplante e três morreram. Estágio avançado de DRC no acometimento (RR = 2,16, IC = 1,14-4,09), proteinúria nefrótica (RR = 2,89, IC = 1,49-5,62), idade (RR - 1,10, IC = 1,01-1,17), escore Z da pressão arterial sistólica (RR = 1,36, IC = 1,08-1,70) e anemia (RR = 2,60, IC - 1,41-4,77) foram associados ao resultado. Foi detectada interação entre anemia e proteinúria nefrótica na primeira visita (V1) (RR = 0,25, IC = 0,06-1,00). Conclusões: Como a primeira coorte de DRC no hemisfério sul, este estudo é concordante com os principais fatores relatados em países desenvolvidos com relação à progressão da DRC, afirmando o possível papel dos tratamentos para mostrar a evolução da DRC. A interação detectada sugere que a anemia pode ser mais nociva na progressão da DRC em pacientes sem proteinúria e deve ser ainda mais estudada.
Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Adolescente , Progressão da Doença , Insuficiência Renal Crônica/fisiopatologia , Fatores Socioeconômicos , Estudos Prospectivos , Fatores de Risco , Estudos de CoortesRESUMO
OBJECTIVE: To identify risk factors for chronic kidney disease progression in Brazilian children and to evaluate the interactions between factors. METHODS: This was a multicenter prospective cohort in São Paulo, involving 209 children with CKD stages 3-4. The study outcome included: (a) death, (b) start of kidney replacement therapy, (c) eGFR decrease >50% during the followup. Thirteen risk factors were tested using univariate regression models, followed by multivariable Cox regression models. The terms of interaction between the variables showing significant association with the outcome were then introduced to the model. RESULTS: After a median follow-up of 2.5 years (IQR=1.4-3.0), the outcome occurred in 44 cases (21%): 22 started dialysis, 12 had >50% eGFR decrease, seven underwent transplantation, and three died. Advanced CKD stage at onset (HR=2.16, CI=1.14-4.09), nephrotic proteinuria (HR=2.89, CI=1.49-5.62), age (HR=1.10, CI=1.01-1.17), systolic blood pressure Z score (HR=1.36, CI=1.08-1.70), and anemia (HR=2.60, CI=1.41-4.77) were associated with the outcome. An interaction between anemia and nephrotic proteinuria at V1 (HR=0.25, CI=0.06-1.00) was detected. CONCLUSIONS: As the first CKD cohort in the southern hemisphere, this study supports the main factors reported in developed countries with regards to CKD progression, affirming the potential role of treatments to slow CKD evolution. The detected interaction suggests that anemia may be more deleterious for CKD progression in patients without proteinuria and should be further studied.
Assuntos
Progressão da Doença , Insuficiência Renal Crônica/fisiopatologia , Adolescente , Criança , Pré-Escolar , Estudos de Coortes , Feminino , Humanos , Lactente , Masculino , Estudos Prospectivos , Fatores de Risco , Fatores SocioeconômicosRESUMO
A doença renal crônica, frequentemente silenciosa, pode resultar em mudanças consideráveis na vida do indivíduo, e, dependendo do seu estágio, requer internações para tratamento clínico ou cirúrgico, o que demanda horas de enfermagem na assistência. Trata-se de um estudo descritivo, quantitativo que objetivou descrever o perfil dos pacientes internados na unidade de nefrologia e mensurar a carga de trabalho de enfermagem. Para a coleta de dados, foi utilizado o Nursing Activities Score,durante 47 dias consecutivos. Os pacientes foram, em sua maioria, do sexo masculino, adulto jovem, em estágio crônico da doença e internados para transplante renal. A média da carga foi de 52%, correspondendo a 12,5 horas de assistência, por paciente, nas 24 horas. Esse perfil se assemelha aos pacientes assistidos na unidade de terapia intensiva, tornando importante para o gerente de enfermagem reavaliar o quadro de pessoal para a assistência, e outros estudos serão necessários para reavaliar a carga requerida por esse perfil de pacientes.
Chronic kidney failure (CKF), which is frequently silent, can lead to considerable changes in the lives of patients. Depending on the stage, hospitalization and hours of nursing care are required to ensure medical and surgical treatment. The aim of this descriptive and quantitative study is to measure nursing workload at a nephrology unit based on daily application of the Nursing Activities Score (NAS) for 47 consecutive days. Patients were mostly young male adults in the chronic stage of the disease or admitted for kidney transplant. A total of 833 observations were obtained from 62 patients. The resulting NAS workload upon admission was 52%, corresponding to 12.5 hours of care per patient for 24 hours, which is similar to the workload found in intensive care units. This profile allows calculation of nursing work hours required for each patient, and is a valuable tool for nursing managers when determining the number of staff members required to ensure assistance. Other studies should be conducted for clinical validation.
La enfermedad renal crónica (ERC), frecuentemente silenciosa, puede resultar en cambios considerables en la vida del individuo y dependiendo de su etapa exige hospitalización para el tratamiento médico o quirúrgico, que necesita horas de atención de la enfermería. Estudio descriptivo, cuantitativo con objeto de describir el perfil de los pacientes hospitalizados en la unidad de nefrología y mensurar la carga de trabajo de enfermería, con la aplicación diaria del Nursing Activities Score (NAS) durante 47 días consecutivos. Los pacientes eran en su mayoría hombres jóvenes de mayor edad, en etapa crónica de la enfermedad y hospitalizados por trasplante de riñón. La carga de trabajo resultante del NAS fue del 52%, correspondiente a 12,5 horas de atención, por cliente, por 24 horas. Este perfil es similar al de los pacientes tratados en la unidad de cuidados intensivos a ser importante que la enfermera gestora evalúe al personal de asistencia y si necesitan otros estudios para evaluar la carga exigida por este perfil de pacientes.